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    • 1. 发明授权
    • Smart pipette for cell manipulation and cell manipulation method for using the smart pipette
    • 用于细胞操作的智能移液器和使用智能移液器的细胞操作方法
    • US07501096B2
    • 2009-03-10
    • US10805871
    • 2004-03-22
    • Byung-Kyu KimYoung-Ho KimDeok-Ho KimJong-Oh Park
    • Byung-Kyu KimYoung-Ho KimDeok-Ho KimJong-Oh Park
    • B01L3/02
    • C12M33/04B01L3/021
    • The present invention relates to a smart pipette for bio-cell manipulation which can freely change orientation of a bio-cell subject to the manipulation by using mechanical friction and applying instantaneous impact when penetrating the subject bio-cell while receiving real-time feedback of force/torque information of the bio-cell. Further, the present invention relates to a bio-cell manipulation method and system using a smart pipette, through which a bio-cell may be manipulated upon the application of the force/torque information generated during the cell manipulation to the smart pipette control. According to the present invention, injection position can be recognized precisely and conveniently regardless of the proficiency of the manipulating person. Thus, the bio-cell manipulation may be automated. Further, the smart pipette quantifies force/torque information feed-backed through the sensor unit and compares it with data acquired in advance through experiments on the same bio-cell. Further, through conducting impact driving when necessary, the present invention makes it possible to conduct bio-cell manipulation with minimum physical damage.
    • 本发明涉及用于生物细胞操作的智能移液器,其可以通过使用机械摩擦自由地改变受到操纵的生物体的取向,并且在接受实时反馈的力时穿透受试者生物细胞时施加瞬时冲击 /生物细胞的扭矩信息。 此外,本发明涉及使用智能移液器的生物细胞操作方法和系统,通过该智能移液管,可以在将细胞操作期间产生的力/扭矩信息应用于智能移液管控制时操纵生物体。 根据本发明,无论操纵者的熟练程度如何,都可以精确而方便地识别注射位置。 因此,生物细胞操作可以是自动化的。 此外,智能移液器量化通过传感器单元反馈的力/扭矩信息,并将其与通过在相同生物细胞上的实验预先获得的数据进行比较。 此外,通过在必要时进行冲击驱动,本发明能够以最小的物理损伤进行生物细胞操作。
    • 2. 发明授权
    • Methods and apparatuses of separating cells using magnets and droplet type cell suspension
    • 使用磁体和液滴型细胞悬浮液分离细胞的方法和装置
    • US07189560B2
    • 2007-03-13
    • US10878357
    • 2004-06-28
    • Young-Ho KimByeong-Kwon JuSeok YunYu-Ri KangKyeong-Kap PaekJin-Woo LeeByung Kyu KimJong Oh Park
    • Young-Ho KimByeong-Kwon JuSeok YunYu-Ri KangKyeong-Kap PaekJin-Woo LeeByung Kyu KimJong Oh Park
    • C12M1/42
    • C12M47/04C12M47/02C12N1/02
    • Disclosed are methods and apparatuses for separating cells using magnets and droplet type cell suspension according to the present invention, which may effectively separate cells by forming droplet type cell suspension with cell suspension sample containing cells to which magnetic beads are coupled and applying magnetic force to the droplet type cell suspension.The apparatus of separating cells according to the present invention includes: a droplet type cell suspension forming part for forming a droplet type cell suspension under a lower part of the droplet type cell suspension forming part with cell suspension sample containing cells to which magnetic beads are coupled; a cell suspension inlet for supplying the droplet type cell suspension forming part with the cell suspension sample; a magnet for applying magnetic force to the droplet type cell suspension; a cell buffer inlet for supplying the droplet type cell suspension with cell buffer; and a temperature maintaining part for maintaining a temperature of the droplet type cell suspension.
    • 公开了根据本发明的使用磁体和液滴型细胞悬浮液分离细胞的方法和装置,其可以通过用含有磁珠耦合的细胞的细胞悬液样品形成液滴型细胞悬浮液来有效地分离细胞,并将磁力施加到 液滴型细胞悬浮液。 根据本发明的分离细胞的装置包括:液滴型细胞悬浮液形成部分,用于在液滴型细胞悬浮液形成部分的下部形成液滴型细胞悬浮液,其中细胞悬液样品含有磁珠偶合的细胞 ; 用于向液滴型细胞悬浮液形成部分供应细胞悬液样品的细胞悬液入口; 用于向液滴型细胞悬浮液施加磁力的磁体; 用于向液滴型细胞悬液提供细胞缓冲液的细胞缓冲液入口; 以及用于保持液滴型细胞悬浮液的温度的温度保持部。
    • 6. 发明申请
    • LIQUID CRYSTAL DISPLAY DEVICE AND METHOD OF DRIVING THE SAME
    • 液晶显示装置及其驱动方法
    • US20120146967A1
    • 2012-06-14
    • US13314698
    • 2011-12-08
    • Min-Kyu KimYoung-Ho KimSung-Jo Koo
    • Min-Kyu KimYoung-Ho KimSung-Jo Koo
    • G06F3/038
    • G09G3/3614G09G3/3688G09G2310/0283G09G2310/0286
    • The liquid crystal display device includes a display panel for displaying a picture thereon, first to (n)th upper data drive ICs for supplying pixel voltages to one side of each data line in the display panel, first to (n)th bottom data drive ICs for supplying pixel voltages to the other side of each data line, a first timing controller for generating an upper data control signal and for controlling operation of the upper data drive ICs, and a second timing controller for generating a bottom data control signal and for controlling operation of the bottom data drive ICs wherein at least one of the first and second timing controllers analyzes the picture data applied thereto and controls the polarities of the pixel voltages to be forwarded from the upper data drive ICs and the bottom data drive ICs with reference to the result of the analysis.
    • 液晶显示装置包括用于在其上显示图像的显示面板,第一至第(n)个用于向显示面板中的每条数据线的一侧提供像素电压的上部数据驱动IC,第一至第(n)个底部数据驱动 用于将像素电压提供给每条数据线的另一侧的IC,用于产生上数据控制信号并用于控制上数据驱动IC的操作的第一定时控制器,以及用于产生下数据控制信号的第二定时控制器, 控制底部数据驱动IC的操作,其中第一和第二定时控制器中的至少一个分析施加到其上的图像数据,并且以参考的方式控制要从上部数据驱动IC和底部数据驱动IC转发的像素电压的极性 分析结果。