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1. 发明授权

US08999129B2 Liquid and gel electrodes for transverse free flow electrophoresis 有权
标题翻译：用于横向自由电泳的液体和凝胶电极
公开(公告)号：US08999129B2
公开(公告)日：2015-04-07
申请号：US13413161
申请日：2012-03-06
申请人： Byoungsok Jung , Klint A. Rose , Maxim Shusteff , Alexandre Persat , Juan Santiago
发明人： Byoungsok Jung , Klint A. Rose , Maxim Shusteff , Alexandre Persat , Juan Santiago
IPC分类号： G01N27/447 , B01D57/02 , B01D43/00
CPC分类号： B01D43/00 , B01D57/02 , G01N27/44769
摘要： The present invention provides a mechanism for separating or isolating charged particles under the influence of an electric field without metal electrodes being in direct contact with the sample solution. The metal electrodes normally in contact with the sample are replaced with high conductivity fluid electrodes situated parallel and adjacent to the sample. When the fluid electrodes transmit the electric field across the sample, particles within the sample migrate according to their electrophoretic mobility.
摘要翻译：本发明提供了一种用于在没有金属电极与样品溶液直接接触的电场的影响下分离或分离带电粒子的机理。通常与样品接触的金属电极被替换为与样品平行且相邻的高导电性流体电极。当流体电极跨越样品传播电场时，样品内的颗粒根据其电泳迁移率而迁移。

2. 发明申请

US20120228141A1 LIQUID AND GEL ELECTRODES FOR TRANSVERSE FREE FLOW ELECTROPHORESIS 有权
标题翻译：液体和凝胶电极用于横向自由流动电泳
公开(公告)号：US20120228141A1
公开(公告)日：2012-09-13
申请号：US13413161
申请日：2012-03-06
申请人： Byoungsok Jung , Klint A. Rose , Maxim Shusteff , Alexandre Persat , Juan Santiago
发明人： Byoungsok Jung , Klint A. Rose , Maxim Shusteff , Alexandre Persat , Juan Santiago
IPC分类号： C25B9/00 , B01D43/00
CPC分类号： B01D43/00 , B01D57/02 , G01N27/44769
摘要： The present invention provides a mechanism for separating or isolating charged particles under the influence of an electric field without metal electrodes being in direct contact with the sample solution. The metal electrodes normally in contact with the sample are replaced with high conductivity fluid electrodes situated parallel and adjacent to the sample. When the fluid electrodes transmit the electric field across the sample, particles within the sample migrate according to their electrophoretic mobility.
摘要翻译：本发明提供了一种用于在没有金属电极与样品溶液直接接触的电场的影响下分离或分离带电粒子的机理。通常与样品接触的金属电极被替换为与样品平行且相邻的高导电性流体电极。当流体电极跨越样品传播电场时，样品内的颗粒根据其电泳迁移率而迁移。

3. 发明授权

US08727129B2 Microfluidic ultrasonic particle separators with engineered node locations and geometries 有权
标题翻译：具有工程节点位置和几何形状的微流体超声波颗粒分离器
公开(公告)号：US08727129B2
公开(公告)日：2014-05-20
申请号：US13571640
申请日：2012-08-10
申请人： Klint A. Rose , Karl A. Fisher , Douglas A. Wajda , Raymond P. Mariella, Jr. , Christopher Bailey , Dietrich Dehlinger , Maxim Shusteff , Byoungsok Jung , Kevin D. Ness
发明人： Klint A. Rose , Karl A. Fisher , Douglas A. Wajda , Raymond P. Mariella, Jr. , Christopher Bailey , Dietrich Dehlinger , Maxim Shusteff , Byoungsok Jung , Kevin D. Ness
IPC分类号： B03B5/00
CPC分类号： B01L3/50273 , B01D21/28 , B01D21/283 , B01D2221/10 , B01L3/502761 , B01L2200/0631 , B01L2200/0636 , B01L2200/0652 , B01L2300/0816 , B01L2300/0864 , B01L2400/0439 , B01L2400/0487 , G01N1/4077 , G01N33/48728 , G01N33/491 , G01N2001/4094
摘要： An ultrasonic microfluidic system includes a separation channel for conveying a sample fluid containing small particles and large particles, flowing substantially parallel, adjacent to a recovery fluid, with which it is in contact. An acoustic transducer produces an ultrasound standing wave, that generates a pressure field having at least one node of minimum pressure amplitude. An acoustic extension structure is located proximate to said separation channel for positioning said acoustic node off center in said acoustic area and concentrating the large particles in said recovery fluid stream.
摘要翻译：超声波微流体系统包括用于输送包含小颗粒和大颗粒的样品流体的分离通道，所述样品流体基本上平行于与其接触的回收流体相邻流动。声换能器产生超声驻波，其产生具有至少一个最小压力振幅节点的压力场。声学延伸结构位于所述分离通道附近，用于将所述声音节点偏离所述声学区域的中心，并将大颗粒集中在所述回收流体流中。

4. 发明申请

US20130043170A1 Microfluidic ultrasonic particle separators with engineered node locations and geometries 有权
标题翻译：具有工程节点位置和几何形状的微流体超声波颗粒分离器
公开(公告)号：US20130043170A1
公开(公告)日：2013-02-21
申请号：US13571640
申请日：2012-08-10
申请人： Klint A. Rose , Karl A. Fisher , Douglas A. Wajda , Raymond P. Mariella, JR. , Christopher Bailey , Dietrich Dehlinger , Maxim Shusteff , Byoungsok Jung , Kevin D. Ness
发明人： Klint A. Rose , Karl A. Fisher , Douglas A. Wajda , Raymond P. Mariella, JR. , Christopher Bailey , Dietrich Dehlinger , Maxim Shusteff , Byoungsok Jung , Kevin D. Ness
IPC分类号： B03B5/60
CPC分类号： B01L3/50273 , B01D21/28 , B01D21/283 , B01D2221/10 , B01L3/502761 , B01L2200/0631 , B01L2200/0636 , B01L2200/0652 , B01L2300/0816 , B01L2300/0864 , B01L2400/0439 , B01L2400/0487 , G01N1/4077 , G01N33/48728 , G01N33/491 , G01N2001/4094
摘要： An ultrasonic microfluidic system includes a separation channel for conveying a sample fluid containing small particles and large particles, flowing substantially parallel, adjacent to a recovery fluid, with which it is in contact. An acoustic transducer produces an ultrasound standing wave, that generates a pressure field having at least one node of minimum pressure amplitude. An acoustic extension structure is located proximate to said separation channel for positioning said acoustic node off center in said acoustic area and concentrating the large particles in said recovery fluid stream.
摘要翻译：超声波微流体系统包括用于输送包含小颗粒和大颗粒的样品流体的分离通道，所述样品流体基本上平行于与其接触的回收流体相邻流动。声换能器产生超声驻波，其产生具有至少一个最小压力振幅节点的压力场。声学延伸结构位于所述分离通道附近，用于将所述声音节点偏离所述声学区域的中心，并将大颗粒集中在所述回收流体流中。

5. 发明申请

US20110259745A1 Three Dimensional Microelectrode System For Dielectrophoresis 有权
标题翻译：用于电泳的三维微电极系统
公开(公告)号：US20110259745A1
公开(公告)日：2011-10-27
申请号：US12843269
申请日：2010-07-26
申请人： Dietrich A. Dehlinger , Klint A. Rose , Maxim Shusteff , Christopher G. Bailey , Raymond P. Mariella, JR.
发明人： Dietrich A. Dehlinger , Klint A. Rose , Maxim Shusteff , Christopher G. Bailey , Raymond P. Mariella, JR.
IPC分类号： B03C5/02
CPC分类号： B03C5/005 , B01L2400/0424 , B03C5/026 , G01N27/447
摘要： A dielectrophoresis apparatus for separating particles from a sample, including an apparatus body; a dielectrophoresis channel in the apparatus body, the dielectrophoresis channel having a central axis, a bottom, a top, a first side, and a second side; a first mesa projecting into the dielectrophoresis channel from the bottom and extending from the first side across the dielectrophoresis channel to the second side, the first mesa extending at an angle to the central axis of the dielectrophoresis channel; a first electrode extending along the first mesa; a second mesa projecting into the dielectrophoresis channel from the bottom and extending from the first side across the dielectrophoresis channel to the second side, the second mesa extending at an angle to the central axis of the dielectrophoresis channel; a space between at least one of the first electrode and the second side or the second electrode and the second side; and a gap between the first electrode and the second electrode.
摘要翻译：一种用于从样品中分离颗粒的介电电泳装置，包括装置体; 所述设备主体中的介电电泳通道，所述介电电泳通道具有中心轴线，底部，顶部，第一侧面和第二侧面; 第一台面从底部突出到介电电泳通道中并且从第一侧穿过介电电泳通道延伸到第二侧，第一台面以与介电电泳通道的中心轴线成一定角度延伸; 沿第一台面延伸的第一电极; 第二台面从底部突出到介电电泳通道中，并从第一侧穿过介电电泳通道延伸到第二侧，第二台面以与介电电泳通道的中心轴成一定角度延伸; 第一电极和第二电极和第二电极和第二侧中的至少一个之间的空间; 以及第一电极和第二电极之间的间隙。

6. 发明授权

US08524064B2 Three dimensional microelectrode system for dielectrophoresis 有权
标题翻译：用于介电电泳的三维微电极系统
公开(公告)号：US08524064B2
公开(公告)日：2013-09-03
申请号：US12843269
申请日：2010-07-26
申请人： Dietrich A. Dehlinger , Klint A. Rose , Maxim Shusteff , Christopher G. Bailey , Raymond P. Mariella, Jr.
发明人： Dietrich A. Dehlinger , Klint A. Rose , Maxim Shusteff , Christopher G. Bailey , Raymond P. Mariella, Jr.
IPC分类号： G01N27/26 , G01N27/453 , B03C5/02 , B01D57/02
CPC分类号： B03C5/005 , B01L2400/0424 , B03C5/026 , G01N27/447
摘要： A dielectrophoresis apparatus for separating particles from a sample, including an apparatus body; a dielectrophoresis channel in the apparatus body, the dielectrophoresis channel having a central axis, a bottom, a top, a first side, and a second side; a first mesa projecting into the dielectrophoresis channel from the bottom and extending from the first side across the dielectrophoresis channel to the second side, the first mesa extending at an angle to the central axis of the dielectrophoresis channel; a first electrode extending along the first mesa; a second mesa projecting into the dielectrophoresis channel from the bottom and extending from the first side across the dielectrophoresis channel to the second side, the second mesa extending at an angle to the central axis of the dielectrophoresis channel; a space between at least one of the first electrode and the second side or the second electrode and the second side; and a gap between the first electrode and the second electrode.
摘要翻译：一种用于从样品中分离颗粒的介电电泳装置，包括装置体; 所述设备主体中的介电电泳通道，所述介电电泳通道具有中心轴线，底部，顶部，第一侧面和第二侧面; 第一台面从底部突出到介电电泳通道中并且从第一侧穿过介电电泳通道延伸到第二侧，第一台面以与介电电泳通道的中心轴线成一定角度延伸; 沿第一台面延伸的第一电极; 第二台面从底部突出到介电电泳通道中，并从第一侧穿过介电电泳通道延伸到第二侧，第二台面以与介电电泳通道的中心轴成一定角度延伸; 第一电极和第二电极和第二电极和第二侧中的至少一个之间的空间; 以及第一电极和第二电极之间的间隙。

7. 发明申请

US20130306481A1 THREE DIMENSIONAL MICROELECTRODE SYSTEM FOR DIELECTROPHORESIS 有权
标题翻译：三维微电子系统用于电介质
公开(公告)号：US20130306481A1
公开(公告)日：2013-11-21
申请号：US13945768
申请日：2013-07-18
申请人： Dietrich A. Dehlinger , Klint A. Rose , Maxim Shusteff , Christopher G. Bailey , Raymond P. Mariella, JR.
发明人： Dietrich A. Dehlinger , Klint A. Rose , Maxim Shusteff , Christopher G. Bailey , Raymond P. Mariella, JR.
IPC分类号： B03C5/00
CPC分类号： B03C5/005 , B01L2400/0424 , B03C5/026 , G01N27/447
摘要： A dielectrophoresis apparatus for separating particles from a sample, including an apparatus body; a dielectrophoresis channel in the apparatus body, the dielectrophoresis channel having a central axis, a bottom, a top, a first side, and a second side; a first mesa projecting into the dielectrophoresis channel from the bottom and extending from the first side across the dielectrophoresis channel to the second side, the first mesa extending at an angle to the central axis of the dielectrophoresis channel; a first electrode extending along the first mesa; a second mesa projecting into the dielectrophoresis channel from the bottom and extending from the first side across the dielectrophoresis channel to the second side, the second mesa extending at an angle to the central axis of the dielectrophoresis channel; a space between at least one of the first electrode and the second side or the second electrode and the second side; and a gap between the first electrode and the second electrode.
摘要翻译：一种用于从样品中分离颗粒的介电电泳装置，包括装置体; 所述设备主体中的介电电泳通道，所述介电电泳通道具有中心轴线，底部，顶部，第一侧面和第二侧面; 第一台面从底部突出到介电电泳通道中并且从第一侧穿过介电电泳通道延伸到第二侧，第一台面以与介电电泳通道的中心轴线成一定角度延伸; 沿第一台面延伸的第一电极; 从底部突出到介电电泳通道的第二台面，并且从第一侧穿过介电电泳通道延伸到第二侧，第二台面以与介电电泳通道的中心轴线成一定角度延伸; 第一电极和第二电极和第二电极和第二侧中的至少一个之间的空间; 以及第一电极和第二电极之间的间隙。

8. 发明授权

US11072160B2 System and method for stimulated emission depletion projection stereolithography 有权
公开(公告)号：US11072160B2
公开(公告)日：2021-07-27
申请号：US15244605
申请日：2016-08-23
申请人： Ryan Hensleigh , Bryan D. Moran , Julie A. Jackson , Eric Duoss , Brett Kelly , Maxim Shusteff , Hayden Taylor , Christopher Spadaccini
发明人： Ryan Hensleigh , Bryan D. Moran , Julie A. Jackson , Eric Duoss , Brett Kelly , Maxim Shusteff , Hayden Taylor , Christopher Spadaccini
IPC分类号： B33Y30/00 , B33Y10/00 , B29C64/129 , B29C64/135
摘要： The present disclosure relates to a system for forming a three dimensional (3D) part. The system may incorporate a beam delivery subsystem for generating optical signals, and a mask subsystem that receives the optical signals and generates optical images therefrom. A first one of the optical images activates a polymerization species of a photo-sensitive resin in accordance with illuminated areas thereof, to thus cause polymerization of select portions of the photo-sensitive resin to help form a layer of the 3D part. A second one of the optical images causes stimulated emission depletion of subportions of the polymerization species, simultaneously, over various areas of the layer, to enhance resolution of at least one subportion of the select portions of the photo-sensitive resin.

9. 发明授权

US10647061B2 System and method for computed axial lithography (CAL) for 3D additive manufacturing 有权
公开(公告)号：US10647061B2
公开(公告)日：2020-05-12
申请号：US15593947
申请日：2017-05-12
申请人： Brett Kelly , Robert Panas , Maxim Shusteff , Christopher Spadaccini , Hayden Taylor , Indrasen Bhattacharya
发明人： Brett Kelly , Robert Panas , Maxim Shusteff , Christopher Spadaccini , Hayden Taylor , Indrasen Bhattacharya
IPC分类号： B29C64/30 , B29C64/393 , B29C64/129 , B29C64/277 , B33Y50/02 , B29C64/245 , B29C64/241 , B29C64/264 , B29C64/232 , B33Y10/00 , B33Y30/00
摘要： A method of forming a three dimensional (3D) object is disclosed. The method may involve providing a volume of photo-curable resin contained within an optically transparent resin container, and simultaneously directing optical projections from an optical subsystem at a plurality of angles θ through the volume of photo-curable resin. The optical beams are directed about a z axis extending through the volume of photo-curable resin. Each of the projections is provided with a calculated 2D spatial intensity function which creates a 3D intensity map. The projections act over a fixed temporal exposure period, during which the net exposure dose is sufficient to cure select portions of the volume of photo-curable resin, and to leave other portions uncured, to form a desired 3D part.

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