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1. 发明授权

US06986992B2 P450 single nucleotide polymorphism biochip analysis 失效
标题翻译： P450单核苷酸多态性生物芯片分析
公开(公告)号：US06986992B2
公开(公告)日：2006-01-17
申请号：US10114908
申请日：2002-04-01
申请人： Buena Chui , Robert Elghanian , Vineet Gupta , Krishnamurthy Jayaraman , Gretchen Kiser , Changming Li , Chang-Gong Liu , Kenneth R. Luehrsen , Abhijit Mazumder , Ramesh Ramakrishnan , Arkadiy Silbergleyt , Todd Tuggle , Carl Yamashiro , Handy Yowanto , Ekaterina Pestova , David R. Fermin , David G. Wang , Zhijie John Gu
发明人： Buena Chui , Robert Elghanian , Vineet Gupta , Krishnamurthy Jayaraman , Gretchen Kiser , Changming Li , Chang-Gong Liu , Kenneth R. Luehrsen , Abhijit Mazumder , Ramesh Ramakrishnan , Arkadiy Silbergleyt , Todd Tuggle , Carl Yamashiro , Handy Yowanto , Ekaterina Pestova , David R. Fermin , David G. Wang , Zhijie John Gu
IPC分类号： C12Q1/68
CPC分类号： B82Y30/00 , C12Q1/6837 , C12Q1/6881 , C12Q1/6883 , C12Q2600/156 , C12Q2600/172 , C12Q2535/125
摘要： This invention relates to methods and compositions for determining single nucleotide polymorphisms (SNPs) in P450 genes. In preferred embodiments, self extension of interrogation probes is prevented by using novel non self-extension probes and/or methods, thereby improving the specificity and efficiency of P450 SNP detection in target samples with minimal false positive results. The invention thus describes a variety of methods to decrease self-extension of interrogation probes. In addition, this invention provides a unique collection of P450 SNP probes on one assay, primer sequences for specific amplification of each of the seven P450 genes and amplicon control probes to evaluate whether the intended p450 gene targets were amplified successfully. The invention also describes a variety of array platforms for performing the assays of the invention; for example: CodeLink™, eSensor™, multiplex arrays with cartridges etc., all described herein.
摘要翻译：本发明涉及用于测定P450基因单核苷酸多态性（SNPs）的方法和组合物。在优选的实施方案中，通过使用新的非自扩增探针和/或方法来阻止询问探针的自身延伸，从而以最小的假阳性结果提高目标样品中P450 SNP检测的特异性和效率。因此，本发明描述了减少询问探针自身延伸的各种方法。此外，本发明在一个测定中提供P450 SNP探针的独特收集，用于七个P450基因和扩增子对照探针中的每一个的特异性扩增的引物序列，以评估是否成功扩增了预期的p450基因靶标。本发明还描述了用于进行本发明测定的各种阵列平台; 例如：CodeLink TM，eSensor TM，带有墨盒的多重阵列等。

2. 发明申请

US20070144354A1 AUTOMATED MONITORING OF THE CONDITION OF AN AIR FILTER IN AN ELECTRONICS SYSTEM 审中-公开
标题翻译：自动监测电子系统中空气过滤器的状况
公开(公告)号：US20070144354A1
公开(公告)日：2007-06-28
申请号：US11460639
申请日：2006-07-28
申请人： P. Keith Muller , David G. Wang
发明人： P. Keith Muller , David G. Wang
IPC分类号： B01D50/00
CPC分类号： B01D46/0086 , B01D46/4254 , B01D46/448 , B01D2273/30
摘要： A technique for use in monitoring the condition of an air filter in an electronics system involves receiving temperature readings gathered over time by a temperature sensor located in the electronics system that houses the air filter, concluding that at least one of the readings exceeds a reference temperature, concluding that a rate of change of at least some of the readings does not exceed a reference rate, and generating an alarm message indicating that the air filter needs attention.
摘要翻译：用于监测电子系统中的空气过滤器的状况的技术涉及通过位于容纳空气过滤器的电子系统中的温度传感器接收随时间收集的温度读数，认为读数中的至少一个超过参考温度得出结论，至少一些读数的变化率不超过参考速率，并产生指示空气过滤器需要注意的报警消息。

3. 发明授权

US06920797B1 Selecting an airflow generator for a system 失效
标题翻译：选择系统的气流发生器
公开(公告)号：US06920797B1
公开(公告)日：2005-07-26
申请号：US10202806
申请日：2002-07-25
申请人： David G. Wang
发明人： David G. Wang
IPC分类号： G01F1/00
CPC分类号： G01F1/00
摘要： A test apparatus includes a plurality of sensors placed proximate an airflow generator (e.g. a fan) to measure flow rates in respective sub-regions. The test apparatus also includes a controller (e.g., test software) to calculate an operating point of the airflow generator based on flow rate data from the sensors and to determine if the operating print falls within a predefined operating range of the airflow generator. Based on this determination, the controller is able to indicate if the airflow generator is appropriate for use in a given system chassis.
摘要翻译：测试装置包括靠近气流发生器（例如风扇）放置的多个传感器，以测量各个子区域中的流量。测试装置还包括基于来自传感器的流量数据计算气流发生器的操作点的控制器（例如，测试软件），并且确定操作打印是否落在气流发生器的预定操作范围内。基于该确定，控制器能够指示气流发生器是否适合在给定的系统底盘中使用。

4. 依法登记的发明

USH2220H1 Identification and mapping of single nucleotide polymorphisms in the human genome 有权
公开(公告)号：USH2220H1
公开(公告)日：2008-07-01
申请号：US10301480
申请日：2002-11-21
申请人： David G. Wang
发明人： David G. Wang
IPC分类号： C07H21/02
摘要： The invention relates to the role of genes in human diseases. More particularly, the invention relates to compositions and methods for identifying genes that are involved in human disease conditions. The invention provides identification and mapping of a very large number of SNPs throughout the entire human genome. This contribution allows scientists to isolate and identify genes that are relevant to the prevention, causation, or treatment of human disease conditions.

5. 依法登记的发明

USH2191H1 Identification and mapping of single nucleotide polymorphisms in the human genome 有权
公开(公告)号：USH2191H1
公开(公告)日：2007-06-05
申请号：US09925065
申请日：2001-08-08
申请人： David G. Wang
发明人： David G. Wang
IPC分类号： C12Q1/68
摘要： The invention relates to the role of genes in human diseases. More particularly, the invention relates to compositions and methods for identifying genes that are involved in human disease conditions. The invention provides identification and mapping of a very large number of SNPs throughout the entire human genome. This contribution allows scientists to isolate and identify genes that are relevant to the prevention, causation, or treatment of human disease conditions.

6. 发明授权

US06760222B1 Dissipating heat using a heat conduit 失效
标题翻译：使用热导管散热
公开(公告)号：US06760222B1
公开(公告)日：2004-07-06
申请号：US10153331
申请日：2002-05-21
申请人： David G. Wang
发明人： David G. Wang
IPC分类号： H05K720
CPC分类号： H01L23/427 , H01L2924/0002 , H01L2924/00
摘要： A heat dissipation apparatus has an elongated heat conduit (such as a heat pipe) in thermal communication with a heat spreader for thermally contacting a heat-generating device. The heat spreader has a phase-change mechanism to spread heat within the heat spreader. In one implementation, the phase-change mechanism includes paths for heated vapor flow and cooled liquid flow.
摘要翻译：散热装置具有与用于热接触发热装置的散热器热连通的细长的热导管（例如热管）。散热器具有在散热器内扩散热量的相变机构。在一个实施方案中，相变机构包括用于加热的蒸气流和冷却的液体流的路径。

7. 发明授权

US08892389B1 Determining a condition of a system based on plural measurements 有权
标题翻译：基于多个测量确定系统的状况
公开(公告)号：US08892389B1
公开(公告)日：2014-11-18
申请号：US12058895
申请日：2008-03-31
申请人： P. Keith Muller , David G. Wang
发明人： P. Keith Muller , David G. Wang
IPC分类号： G01K5/66 , G06F11/00 , G06F15/00 , G06F11/30
CPC分类号： G06F11/3003 , G06F11/0706 , G06F11/079 , G06F11/3058
摘要： To determine a system condition, temperature information from at least one temperature sensor in the system is received, along with second information from at least a second type of sensor in the system. An out-of-range temperature condition is detected according to the received temperature information. According to the second information, one of plural potential causes of the out-of-range temperature condition is selected.
摘要翻译：为了确定系统状态，接收来自系统中的至少一个温度传感器的温度信息以及来自系统中的至少第二类型的传感器的第二信息。根据接收的温度信息检测超出范围的温度条件。根据第二信息，选择超出范围温度条件的多个潜在原因之一。

8. 发明授权

US07295444B1 Delivering chilled air to components in a hardware cabinet 有权
标题翻译：将冷却空气送入硬件柜内的组件
公开(公告)号：US07295444B1
公开(公告)日：2007-11-13
申请号：US10749582
申请日：2003-12-31
申请人： David G. Wang
发明人： David G. Wang
IPC分类号： H05K5/00
CPC分类号： H05K7/20736
摘要： A hardware cabinet includes a chassis that is designed for mounting multiple heat-generating electronic systems and a door that allows access into the cabinet. The door has a solid face that extends from the top portion of the door along the majority of the door's length. An opening formed in a lower portion of the door allows chilled air to enter the cabinet. The chassis is structured so that, when electronic systems are mounted in the cabinet, a plenum is formed between the door and the electronic systems. The plenum allows air entering the cabinet to rise between the door and the electronic systems.
摘要翻译：硬件柜包括设计用于安装多个发热电子系统的机箱和允许进入机柜的门。门具有从门的顶部延伸的坚实的面，沿门的大部分长度。形成在门的下部的开口允许冷空气进入柜体。底盘结构使得当电子系统安装在机柜中时，在门和电子系统之间形成一个通风室。通风室允许进入机柜的空气在门和电子系统之间上升。

9. 发明授权

US07236362B2 Minimization of cooling air preheat for maximum packaging density 有权
标题翻译：最小化冷却空气预热，最大限度地提高包装密度
公开(公告)号：US07236362B2
公开(公告)日：2007-06-26
申请号：US10992451
申请日：2004-11-18
申请人： David G. Wang , P. Keith Muller
发明人： David G. Wang , P. Keith Muller
IPC分类号： H05K7/20
CPC分类号： H05K7/20572
摘要： An electronic hardware cabinet includes a forced-air component positioned to force a stream of air to move through the cabinet and at least two electronic assemblies mounted within the cabinet, each of which includes a heat-generating component. The electronic assemblies are positioned so that a portion of the stream of air is heated by a first one of the heat-generating components and, thereafter, that portion of the stream of air moves toward a second one of the heat-generating components. An airflow diverter is positioned between the electronic assemblies to deflect that portion of the stream of air heated by the first heat-generating component to prevent it from reaching the second heat-generating component.
摘要翻译：电子硬件柜包括强制空气部件，该强制空气部件被定位成迫使空气流移动通过机壳，以及安装在机柜内的至少两个电子组件，每个电子组件包括发热部件。电子组件被定位成使得空气流的一部分被第一个发热部件加热，此后，空气流的那部分向第二个发热部件移动。气流分流器定位在电子组件之间，以偏转由第一发热部件加热的空气流的部分，以防止其到达第二发热部件。

10. 发明授权

US07124806B1 Heat sink for enhanced heat dissipation 失效
标题翻译：散热器用于增强散热
公开(公告)号：US07124806B1
公开(公告)日：2006-10-24
申请号：US10016624
申请日：2001-12-10
申请人： David G. Wang , P. Keith Muller
发明人： David G. Wang , P. Keith Muller
IPC分类号： F28F7/00
CPC分类号： F28D15/04 , F28D15/0266 , F28D15/0275 , F28D2021/0029 , F28F1/32 , F28F7/02 , F28F2013/001 , F28F2215/08 , H01L23/427 , H01L23/467 , H01L2924/0002 , H01L2924/00
摘要： A heat sink assembly includes a block formed of a thermally conductive material. For example, the thermally conductive material includes thermally conductive polymer. A heat conduit (e.g., a heat pipe) extends through a substantial portion of the block. In one example arrangement, airflow channels extend through portions of the block.
摘要翻译：散热器组件包括由导热材料形成的块体。例如，导热材料包括导热聚合物。热导管（例如，热管）延伸穿过块的大部分。在一个示例性布置中，气流通道延伸穿过块的一部分。

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