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1. 发明申请

US20060173179A1 Azabenzoxazoles for the treatment of CNS disorders 审中-公开
标题翻译：用于治疗CNS疾病的Azabenzoxazoles
公开(公告)号：US20060173179A1
公开(公告)日：2006-08-03
申请号：US11273657
申请日：2005-11-14
申请人： Bruce Rogers , Allen Duplantier , Christopher O'Donnell , Lei Zhang , Alisher Khasanov
发明人： Bruce Rogers , Allen Duplantier , Christopher O'Donnell , Lei Zhang , Alisher Khasanov
IPC分类号： C07D487/04
CPC分类号： C07D519/00 , C07D498/04
摘要： The present invention relates to α7 nicotinic receptor agonists of formula I as described herein and to a method for treating disorders of the Central Nervous System (CNS) such as cognitive deficits in schizophrenia, by administering to a mammal an α7 nicotinic receptor agonist of formula I.
摘要翻译：本发明涉及如本文所述的式I的α7烟碱受体激动剂和通过向哺乳动物施用式I的α7烟碱受体激动剂治疗中枢神经系统（CNS）的障碍的精神分裂症认知缺陷的方法，。

2. 发明申请

US20060166974A1 Azabenzoxazoles for the treatment of CNS disorders 审中-公开
标题翻译：用于治疗CNS疾病的Azabenzoxazoles
公开(公告)号：US20060166974A1
公开(公告)日：2006-07-27
申请号：US11271245
申请日：2005-11-11
申请人： Bruce Rogers , Allen Duplantier , Christopher O'Donnell , Lei Zhang
发明人： Bruce Rogers , Allen Duplantier , Christopher O'Donnell , Lei Zhang
IPC分类号： A61K31/551 , C07D487/04
CPC分类号： C07D519/00
摘要： The present invention relates to α7 nicotinic receptor agonists of formula I as described herein and to a method for treating disorders of the Central Nervous System (CNS) such as cognitive deficits in schizophrenia, by administering to a mammal an α7 nicotinic receptor agonist of formula I as shown herein.
摘要翻译：本发明涉及如本文所述的式I的α7烟碱受体激动剂和通过向哺乳动物施用式I的α7烟碱受体激动剂治疗中枢神经系统（CNS）的障碍的精神分裂症认知缺陷的方法，如本文所示。

3. 发明申请

US20070099904A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CNS AND OTHER DISORDERS 失效
标题翻译：用于治疗CNS和其他疾病的药物组合物
公开(公告)号：US20070099904A1
公开(公告)日：2007-05-03
申请号：US11559957
申请日：2006-11-15
申请人： Brian O'Neill , Jotham Coe , Christopher O'Donnell
发明人： Brian O'Neill , Jotham Coe , Christopher O'Donnell
IPC分类号： A61K31/551 , C07D487/04 , C07D491/04 , C07D498/04
CPC分类号： C07D471/08
摘要： The present invention relates to compounds of formula I The substituent designations are as disclosed. At least one of B Q, D and E is nitrogen. The present invention also provides a method of treating disorders of the Central Nervous System such as schizophrenia and cognitive dysfunction.
摘要翻译：本发明涉及式I化合物。取代基名称如所公开。 B Q，D和E中的至少一个是氮。本发明还提供了治疗中枢神经系统疾病如精神分裂症和认知功能障碍的方法。

4. 发明申请

US20050176720A1 Pharmaceutical composition for the treatment of CNS and other disorders 审中-公开
公开(公告)号：US20050176720A1
公开(公告)日：2005-08-11
申请号：US11106778
申请日：2005-04-15
申请人： Brian O'Neill , Jotham Coe , Christopher O'Donnell
发明人： Brian O'Neill , Jotham Coe , Christopher O'Donnell
IPC分类号： A61K31/551 , A61K45/00 , A61P1/04 , A61P3/04 , A61P9/06 , A61P9/08 , A61P9/10 , A61P9/12 , A61P21/02 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/10 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P25/32 , A61P25/34 , A61P25/36 , C07D471/08 , C07D519/00 , A61K31/498
CPC分类号： C07D471/08
摘要： The present invention relates to a method of treating disorders of the Central Nervous System (CNS) and other disorders in a mammal, including a human, by administering to the mammal a CNS-penetrant α7 nicotinic receptor agonist. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier and a CNS-penetrant α7 nicotinic receptor agonist.

5. 发明申请

US20050020616A1 Aryl fused azapolycyclic compounds 审中-公开
标题翻译：芳基稠合的氮杂多环化合物
公开(公告)号：US20050020616A1
公开(公告)日：2005-01-27
申请号：US10889343
申请日：2004-07-12
申请人： Jotham Coe , Christopher O'Donnell
发明人： Jotham Coe , Christopher O'Donnell
IPC分类号： A61P25/00 , C07D221/22 , C07D223/14 , C07D471/08 , C07D498/08 , C07D513/08 , A61K31/4745
CPC分类号： C07D221/22 , C07D223/14 , C07D471/08 , C07D513/08
摘要： This invention is directed to compounds of the formula (I): and their pharmaceutically acceptable salts, wherein R1, R2, R3 and Z are as defined herein; intermediates for the synthesis of such compounds, pharmaceutical compositions containing such compounds; and methods of using such compounds in the treatment of neurological and psychological disorders.
摘要翻译：本发明涉及式（I）化合物及其药学上可接受的盐，其中R 1，R 2，R 3和Z如本文所定义; 用于合成这些化合物的中间体，含有这些化合物的药物组合物; 以及使用这些化合物治疗神经和心理障碍的方法。

6. 发明申请

US20060058361A1 Therapeutic diphenyl ether ligands 审中-公开
标题翻译：治疗二苯醚配体
公开(公告)号：US20060058361A1
公开(公告)日：2006-03-16
申请号：US11223516
申请日：2005-09-09
申请人： Anton Fliri , Christopher O'Donnell , Michelle Claffey , Randall Gallaschun
发明人： Anton Fliri , Christopher O'Donnell , Michelle Claffey , Randall Gallaschun
IPC分类号： A61K31/428 , A61K31/423 , A61K31/421 , A61K31/4184 , A61K31/277 , A61K31/137
CPC分类号： A61K31/137 , A61K31/277 , A61K31/4184 , A61K31/421 , A61K31/423 , A61K31/428 , C07C217/90 , C07C317/32 , C07C323/32 , C07C2602/08 , C07D239/74 , C07D261/20 , C07D307/87 , C07D333/50 , C07D333/72
摘要： This invention is directed to compounds of formula Ia, Ib or Ic and to pharmaceutical compositions thereof: or a prodrug thereof and a pharmaceutically acceptable carrier, wherein the R groups are defined in the specification; and, in which the dashed line represents an optional double bond. The invention is also directed to methods of treating, diagnosing, and preventing disorders of the central nervous system that are associated with 5HT receptors, including obesity, attention deficit disorder, migraine, depression, epilepsy, anxiety, Alzheimer's disease, withdrawal from drug abuse, pain, schizophrenia, stress-related disorders, panic disorder, sleep disorders, phobias, obsessive compulsive disorder, post-traumatic-stress syndrome, immune system depression, stress-induced gastrointestinal dysfunction, stress-induced cardiovascular dysfunction, and sexual dysfunction.
摘要翻译：本发明涉及式Ia，Ib或Ic化合物及其药物组合物：

7. 发明申请

US20130056142A1 DECORATIVE DECAL FOR RECESSED LIGHT TRIM 审中-公开
标题翻译：装饰灯装饰装饰
公开(公告)号：US20130056142A1
公开(公告)日：2013-03-07
申请号：US13602740
申请日：2012-09-04
申请人： Joseph W. Fiore , Christopher O'Donnell
发明人： Joseph W. Fiore , Christopher O'Donnell
IPC分类号： B32B38/10 , B32B33/00 , F21V21/00 , B32B7/12
CPC分类号： B44C1/17 , F21W2121/00 , Y10T428/1476
摘要： A decorative decal assembly for application to a trim of a recessed light assembly having a planar, generally ring-shaped decal which has an outer peripheral edge and an inner peripheral edge, a front surface and an opposite rear surface. The rear surface has an adhesive for adhering the decal to the trim of the recessed lighting. The assembly also including a planar release strip, removably attached to the rear surface of the decal via the adhesive. The release strip is removable from the decal, to permit the rear surface of the decal to be affixed to the trim of the recessed light assembly via the adhesive.
摘要翻译：一种装饰贴花组件，用于应用于具有平坦的大致环形贴花的嵌入式灯组件的装饰，所述凹形灯具具有外周边缘和内周边缘，前表面和相对的后表面。后表面具有用于将贴花贴合到嵌入式照明装饰件的粘合剂。组件还包括平面释放带，通过粘合剂可移除地附接到贴花的后表面。剥离条可以从贴花去除，以允许贴花的后表面通过粘合剂固定到嵌入式灯组件的饰边上。

8. 发明申请

US20070076700A1 Alternative Means for Public Telephone Information Services 审中-公开
标题翻译：公共电话信息服务的其他手段
公开(公告)号：US20070076700A1
公开(公告)日：2007-04-05
申请号：US11609161
申请日：2006-12-11
申请人： Christopher O'Donnell
发明人： Christopher O'Donnell
IPC分类号： H04L12/66
CPC分类号： H04M17/02 , H04L12/66 , H04M3/42306 , H04M3/4931 , H04M7/006 , H04M15/08 , H04M2203/2083 , H04M2215/0192 , H04M2215/62
摘要： A method is provided for managing network services between a plurality of networks comprising receiving an Internet Protocol data packet with a corresponding address from a first network source, wherein the Internet Protocol data packet comprises a header and a payload and the payload of said Internet Protocol data packet contains at least a portion of a destination address; translating the destination address; and delivering the Internet Protocol data packet to a destination node on a second network based on said translating.
摘要翻译：提供了一种用于管理多个网络之间的网络服务的方法，包括从第一网络源接收互联网协议数据分组与相应地址，其中所述因特网协议数据分组包括报头和有效载荷以及所述因特网协议数据的有效载荷分组包含目的地地址的至少一部分; 翻译目的地址; 以及基于所述翻译将所述因特网协议数据分组递送到第二网络上的目的地节点。

9. 发明授权

US07149294B2 Alternative means for public telephone information services 有权
标题翻译：公共电话信息服务的替代手段
公开(公告)号：US07149294B2
公开(公告)日：2006-12-12
申请号：US10449675
申请日：2003-06-02
申请人： Christopher O'Donnell
发明人： Christopher O'Donnell
IPC分类号： H04M15/00 , H04M3/42
CPC分类号： H04M3/4931 , H04M3/42306 , H04M3/4878 , H04M3/493 , H04M15/08 , H04M17/02 , H04M2203/2083 , H04M2215/0192 , H04M2215/62
摘要： A method is described to provide an alternative telephone information service implemented by a service provider other than the telecommunication service used in the connection of the call. This independent information service provides the caller information services at a minimal or at no cost to the caller. The cost of the call to the caller is subsidized or entirely paid by promotion message sponsors in exchange for the caller listening, with possible interaction by the caller and rewards to the caller, to at least one sponsored promotional message prior to connection to the requested information. This service information includes telephone listings, weather, date/time, local/national news, traffic conditions, airplane schedules, text to voice translated caller e-mail, account member mailbox messages or other information of interest to the local or national caller.
摘要翻译：描述了一种方法来提供除了在呼叫的连接中使用的电信服务之外的服务提供商实现的替代电话信息服务。这种独立的信息服务以最小或免费的方式为呼叫者提供呼叫者信息服务。呼叫者的呼叫费用由促销消息赞助者补充或完全支付，以换取呼叫者在连接到所请求的信息之前，呼叫者可能与呼叫者进行交互以及对呼叫者的奖励至少一个赞助的促销消息。该服务信息包括电话列表，天气，日期/时间，本地/国家新闻，交通条件，飞机时刻表，语音翻译呼叫者电子邮件文本，帐户成员信箱消息或本地或国家呼叫者感兴趣的其他信息。

10. 发明申请

US20060014750A1 Pharmaceutical compositions for the treatment of CNS and other disorders 审中-公开
标题翻译：用于治疗CNS和其他疾病的药物组合物
公开(公告)号：US20060014750A1
公开(公告)日：2006-01-19
申请号：US11228449
申请日：2005-09-15
申请人： Christopher O'Donnell , Brian O'Neill
发明人： Christopher O'Donnell , Brian O'Neill
IPC分类号： A61K31/498
CPC分类号： C07D213/30 , C07D231/12 , C07D233/56 , C07D249/08 , C07D471/08
摘要： The present invention relates to a method of treating disorders of the central nervous system (CNS) and other disorders in a mammal, including a human, by administering to the mammal a CNS-penetrant α7 nicotinic receptor agonist. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier and a CNS-penetrant α7 nicotinic receptor agonist.
摘要翻译：本发明涉及一种通过向哺乳动物施用CNS渗透剂α7烟碱受体激动剂来治疗哺乳动物（包括人）中的中枢神经系统（CNS）和其它疾病的疾病的方法。它还涉及含有药学上可接受的载体和CNS渗透剂α7烟碱受体激动剂的药物组合物。

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