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1. 发明授权

US08029511B2 Multi-stage biomaterial injection system for spinal implants 失效
标题翻译：用于脊柱植入物的多级生物材料注射系统
公开(公告)号：US08029511B2
公开(公告)日：2011-10-04
申请号：US10984493
申请日：2004-11-09
申请人： Bruce R. Bowman , Rob Kohler , Erik Martz , Dan Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Garryl Hudgins
发明人： Bruce R. Bowman , Rob Kohler , Erik Martz , Dan Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Garryl Hudgins
IPC分类号： A61B17/58 , A61B17/60 , A61F2/00
CPC分类号： A61B17/8805 , A61B17/8827 , A61B17/8836 , A61B2090/064 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61F2002/30062 , A61F2002/3008 , A61F2002/30583 , A61F2002/4627 , A61F2002/465 , A61F2002/4663 , A61F2002/467 , A61F2002/4677 , A61F2002/4688 , A61F2002/4693 , A61F2002/4694 , A61F2210/0004 , A61F2210/0085 , A61F2250/0098
摘要： A method and apparatus for fluidly coupling a reservoir containing a flowable biomaterial to a mold. The flow of the flowable biomaterial into the mold is controlled in accordance with a first operating parameter. At least one injection condition is monitored. The flow of the flowable biomaterial is controlled in accordance with a second operating parameter in response to one or more of the injection conditions reaching a threshold level. The second operating parameter is maintained during at least a portion of the curing of the flowable biomaterial. In some embodiments, the second operating parameter may optionally include permitting a portion of the flowable biomaterial to be expelled from the mold.
摘要翻译：一种用于将包含可流动的生物材料的容器流体耦合到模具的方法和装置。根据第一操作参数控制可流动的生物材料流入模具的流动。至少监测一个注射条件。响应于达到阈值水平的一个或多个注入条件，可流动生物材料的流动根据第二操作参数来控制。在可流动的生物材料的固化的至少一部分期间维持第二操作参数。在一些实施例中，第二操作参数可以可选地包括允许可流动的生物材料的一部分从模具中排出。

2. 发明申请

US20090076518A1 METHOD AND SYSTEM FOR STABILIZING ADJACENT VERTEBRAE 审中-公开
标题翻译：用于稳定相邻VERTEBRAE的方法和系统
公开(公告)号：US20090076518A1
公开(公告)日：2009-03-19
申请号：US12266301
申请日：2008-11-06
申请人： Bruce R. Bowman , Rob Kohler , Erik Martz , Dan Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Garryl Hudgins
发明人： Bruce R. Bowman , Rob Kohler , Erik Martz , Dan Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Garryl Hudgins
IPC分类号： A61B17/58 , A61B19/00
CPC分类号： A61B17/8805 , A61B17/8827 , A61B17/8836 , A61B2090/064 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61F2002/30062 , A61F2002/3008 , A61F2002/30583 , A61F2002/4627 , A61F2002/465 , A61F2002/4663 , A61F2002/467 , A61F2002/4677 , A61F2002/4688 , A61F2002/4693 , A61F2002/4694 , A61F2210/0004 , A61F2210/0085 , A61F2250/0098
摘要： A method of stabilizing adjacent vertebrae including the steps of forming at least one annulotomy in an annulus. At least a portion of the nucleus material is removed through the annulotomy to form a cavity in an intervertebral disc space between the adjacent vertebrae. A reservoir containing a flowable biomaterial is fluidly coupled to the intervertebral disc space. A flowable biomaterial is delivered to the cavity. The delivery of the flowable biomaterial into the intervertebral disc space is controlled in accordance with at least a first operating parameter. The biomaterial is at least partially cured to stabilize the adjacent vertebrae.
摘要翻译：一种稳定相邻椎骨的方法，包括在环空中形成至少一个瓣膜切开术的步骤。至少一部分细胞核材料通过瓣膜切开术去除以在相邻椎骨之间的椎间盘间隙中形成空腔。包含可流动的生物材料的储存器流体耦合到椎间盘空间。可流动的生物材料被输送到空腔。根据至少第一操作参数控制可流动的生物材料输送到椎间盘空间中。生物材料至少部分固化以稳定相邻的椎骨。

3. 发明申请

US20050209602A1 Multi-stage biomaterial injection system for spinal implants 审中-公开
标题翻译：用于脊柱植入物的多级生物材料注射系统
公开(公告)号：US20050209602A1
公开(公告)日：2005-09-22
申请号：US10984566
申请日：2004-11-09
申请人： Bruce Bowman , Robert Kohler , Erik Martz , Daniel Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Hudgins
发明人： Bruce Bowman , Robert Kohler , Erik Martz , Daniel Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Hudgins
IPC分类号： A61B17/88 , A61B19/00 , A61F2/00 , A61F2/02 , A61F2/30 , A61F2/44 , A61F2/46
CPC分类号： A61B17/8805 , A61B17/8827 , A61B17/8836 , A61B2090/064 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61F2002/30062 , A61F2002/3008 , A61F2002/30583 , A61F2002/4627 , A61F2002/465 , A61F2002/4663 , A61F2002/467 , A61F2002/4677 , A61F2002/4688 , A61F2002/4693 , A61F2002/4694 , A61F2210/0004 , A61F2210/0085 , A61F2250/0098
摘要： A method and apparatus for fluidly coupling a reservoir containing a flowable biomaterial to a mold. The flow of the flowable biomaterial into the mold is controlled in accordance with a first operating parameter. At least one injection condition is monitored. The flow of the flowable biomaterial is controlled in accordance with a second operating parameter in response to one or more of the injection conditions reaching a threshold level. The second operating parameter is maintained during at least a portion of the curing of the flowable biomaterial. In some embodiments, the second operating parameter may optionally include permitting a portion of the flowable biomaterial to be expelled from the mold.
摘要翻译：一种用于将包含可流动的生物材料的容器流体耦合到模具的方法和装置。根据第一操作参数控制可流动的生物材料流入模具的流动。至少监测一个注射条件。响应于达到阈值水平的一个或多个注入条件，可流动生物材料的流动根据第二操作参数来控制。在可流动的生物材料的固化的至少一部分期间维持第二操作参数。在一些实施例中，第二操作参数可以可选地包括允许可流动的生物材料的一部分从模具中排出。

4. 发明申请

US20050209601A1 Multi-stage biomaterial injection system for spinal implants 失效
公开(公告)号：US20050209601A1
公开(公告)日：2005-09-22
申请号：US10984493
申请日：2004-11-09
申请人： Bruce Bowman , Robert Kohler , Erik Martz , Daniel Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Hudgins
发明人： Bruce Bowman , Robert Kohler , Erik Martz , Daniel Melink , Khin Myint , Michael Ahrens , Jean-Charles Lehuec , John Sherman , Scott Hook , Dennis Johnson , Qi-Bin Bao , Robert Hudgins
IPC分类号： A61B17/88 , A61B19/00 , A61F2/00 , A61F2/02 , A61F2/30 , A61F2/44 , A61F2/46
CPC分类号： A61B17/8805 , A61B17/8827 , A61B17/8836 , A61B2090/064 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61F2002/30062 , A61F2002/3008 , A61F2002/30583 , A61F2002/4627 , A61F2002/465 , A61F2002/4663 , A61F2002/467 , A61F2002/4677 , A61F2002/4688 , A61F2002/4693 , A61F2002/4694 , A61F2210/0004 , A61F2210/0085 , A61F2250/0098
摘要： A method and apparatus for fluidly coupling a reservoir containing a flowable biomaterial to a mold. The flow of the flowable biomaterial into the mold is controlled in accordance with a first operating parameter. At least one injection condition is monitored. The flow of the flowable biomaterial is controlled in accordance with a second operating parameter in response to one or more of the injection conditions reaching a threshold level. The second operating parameter is maintained during at least a portion of the curing of the flowable biomaterial. In some embodiments, the second operating parameter may optionally include permitting a portion of the flowable biomaterial to be expelled from the mold.

5. 发明申请

US20060265076A1 Catheter holder for spinal implant 审中-公开
标题翻译：导管支架用于脊柱植入
公开(公告)号：US20060265076A1
公开(公告)日：2006-11-23
申请号：US11268876
申请日：2005-11-08
申请人： Benjamin Carter , Erik Martz , Scott Hook , Mark Rydell , Ronald Burke , Robert Kohler , Steven Healy , Bruce Bowman , John Sherman , Jean-Charles Lehuec
发明人： Benjamin Carter , Erik Martz , Scott Hook , Mark Rydell , Ronald Burke , Robert Kohler , Steven Healy , Bruce Bowman , John Sherman , Jean-Charles Lehuec
IPC分类号： A61F2/44
CPC分类号： A61F2/4611 , A61B1/3135 , A61B17/3415 , A61B90/50 , A61B2017/00261 , A61B2017/3405 , A61B2017/3445 , A61B2017/3447 , A61B2017/3488 , A61F2/441 , A61F2002/4627 , A61M25/04 , A61M25/0662
摘要： A catheter holder designed to deliver a curable biomaterial to an intervertebral disc space. By securing the catheter to the catheter holder, the depth of insertion of the catheter into the disc space can be accurately controlled. The catheter holder optionally helps with insertion of a optional mold through the annulotomy and into the disc space created by the nuclectomy. The catheter holder helps keep the mold from being drawn too far into the disc space or pushed too far out of the disc space during polymer injection.
摘要翻译：设计用于将可固化生物材料递送到椎间盘空间的导管支架。通过将导管固定到导管支架上，可以精确地控制导管插入椎间盘空间的深度。导管支架可选择地有助于插入可选模具通过瓣膜切开术并进入由切除切割术产生的椎间盘空间。在聚合物注射期间，导管支架有助于保持模具不被太吸引到盘片空间中或被推到太远的盘片空间。

6. 发明申请

US20060135959A1 Nuclectomy method and apparatus 审中-公开
标题翻译：核结肠切除术方法和装置
公开(公告)号：US20060135959A1
公开(公告)日：2006-06-22
申请号：US11304053
申请日：2005-12-15
申请人： Hansen Yuan , Scott Hook , Erik Martz
发明人： Hansen Yuan , Scott Hook , Erik Martz
IPC分类号： A61B17/88 , A61F2/44
CPC分类号： A61B17/1606 , A61B34/10 , A61B2017/00261
摘要： A nuclectomy method for creating a nuclear cavity in an annulus located in an intervertebral disc space and for preparing the nuclear cavity to receive an intervertebral prosthesis. An annulotomy is formed in the annulus along an annular axis to provide access to a nucleus. A portion of the nucleus is removed in a first region surrounding the annular axis using at least a first surgical tool. Another portion of the nucleus is removed from a second region using at least a second surgical tool. An evaluation mold is positioned in the nuclear cavity and a fluid is delivered to the evaluation mold so that the mold substantially fills the nuclear cavity. The amount of nucleus removed from the annulus is estimated. One or more of the removing steps are optionally repeated as necessary until an adequate amount of the nucleus is removed from the annulus.
摘要翻译：一种用于在位于椎间盘空间中的环中产生核腔并用于准备核腔以接收椎间假体的核切除术方法。在环形环中沿环形轴线形成瓣膜切开术以提供对细胞核的接近。至少使用第一外科手术工具，在包围环形轴的第一区域中移除核的一部分。使用至少第二外科手术工具从第二区域移除细胞核的另一部分。评估模具定位在核腔中，并将流体输送到评估模具，使得模具基本上填充核腔。估计从环带移除的核的量。根据需要可选地重复一个或多个除去步骤，直到从环空中除去足够量的细胞核。

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