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1. 发明授权

US06178357B1 Electrode pad system and defibrillator electrode pad that reduces the risk of peripheral shock 有权
标题翻译：电极垫系统和除颤器电极垫，减少外围冲击的风险
公开(公告)号：US06178357B1
公开(公告)日：2001-01-23
申请号：US09143701
申请日：1998-08-28
申请人： Bradford E. Gliner , Stephen M. Dillon , Kent W. Leyde
发明人： Bradford E. Gliner , Stephen M. Dillon , Kent W. Leyde
IPC分类号： A61N105
CPC分类号： A61N1/046 , A61N1/0492
摘要： This invention is directed to a medical electrode system having a flexible substrate with two electrodes in electrical communication disposed at either end along its length. The electrode system also has one or more sensors for detecting the rate and pressure at which CPR is administered. The electrode is adjustable in length and protects the user from the potential of incidental shock when using the electrode in conjunction with a defibrillator.
摘要翻译：本发明涉及一种具有柔性基底的医疗电极系统，其中两个电极沿着其长度设置在两端。电极系统还具有一个或多个用于检测施用CPR的速率和压力的传感器。电极的长度是可调节的，并且当使用电极与除颤器一起使用时，可以保护使用者避免偶然的冲击的可能性。

2. 发明授权

US06374137B1 Method and apparatus for reducing defibrillation energy 失效
标题翻译：降低除颤能量的方法和装置
公开(公告)号：US06374137B1
公开(公告)日：2002-04-16
申请号：US09417269
申请日：1999-10-13
申请人： Carlton B. Morgan , Bradford E. Gliner , Dawn Jorgenson , Kent W. Leyde
发明人： Carlton B. Morgan , Bradford E. Gliner , Dawn Jorgenson , Kent W. Leyde
IPC分类号： A61N139
CPC分类号： A61N1/3937 , A61N1/3931
摘要： An energy reduction unit is removably connectable to an external defibrillator to reduce the defibrillation energy delivered by the defibrillator to a patient. Use of the energy reduction unit is particularly suited to defibrillating pediatric patients (infants and children under 8) with an automatic or semi-automatic external defibrillator (AED). In one embodiment, the energy reduction unit includes an attenuator which partially dissipates energy produced by the AED. The attenuator is advantageously designed to present an impedance to the AED which, when connected to the patient, is approximately equal to the patient's impedance. The energy reduction unit may include a presence-detect function which enables the defibrillator to modify analysis of ECG signals to account for differences heart rhythms of pediatric and adult patients. In a second embodiment, the energy reduction unit includes an energy control modifier circuit which affects the charging operations performed internal to the AED. Other than being attached to the defibrillation equipment, the energy reduction unit does not otherwise change how an operator uses the equipment.
摘要翻译：能量减少单元可拆卸地连接到外部除颤器，以减少除颤器向患者传递的除颤能量。能量减少装置的使用特别适用于使用自动或半自动外部除颤器（AED）除纤维化的儿科患者（8岁以下的婴儿和8岁以下的儿童）。在一个实施例中，能量减少单元包括部分耗散由AED产生的能量的衰减器。衰减器有利地被设计成向AED呈现阻抗，其在连接到患者时大致等于患者的阻抗。能量减少单元可以包括存在检测功能，其使除颤器能够修改ECG信号的分析，以解决儿科和成人患者的心律的差异。在第二实施例中，能量减少单元包括影响在AED内部执行的充电操作的能量控制修正器电路。除了附着到除颤设备之外，能量减少单元不会改变操作者如何使用设备。

3. 发明授权

US6134468A Method and apparatus for reducing defibrillation energy 失效
公开(公告)号：US6134468A
公开(公告)日：2000-10-17
申请号：US113803
申请日：1998-07-09
申请人： Carlton B. Morgan , Bradford E. Gliner , Dawn Jorgenson , Kent W. Leyde
发明人： Carlton B. Morgan , Bradford E. Gliner , Dawn Jorgenson , Kent W. Leyde
IPC分类号： A61N1/39
CPC分类号： A61N1/3937 , A61N1/3931
摘要： An energy reduction unit is removably connectable to an external defibrillator to reduce the defibrillation energy delivered by the defibrillator to a patient. Use of the energy reduction unit is particularly suited to defibrillating pediatric patients (infants and children under 8) with an automatic or semi-automatic external defibrillator (AED). In one embodiment, the energy reduction unit includes an attenuator which partially dissipates energy produced by the AED. The attenuator is advantageously designed to present an impedance to the AED which, when connected to the patient, is approximately equal to the patient's impedance. The energy reduction unit may include a presence-detect function which enables the defibrillator to modify analysis of ECG signals to account for differences heart rhythms of pediatric and adult patients. In a second embodiment, the energy reduction unit includes an energy control modifier circuit which affects the charging operations performed internal to the AED. Other than being attached to the defibrillation equipment, the energy reduction unit does not otherwise change how an operator uses the equipment.

4. 发明授权

US06241751B1 Defibrillator with impedance-compensated energy delivery 有权
标题翻译：具有阻抗补偿能量输送的除颤器
公开(公告)号：US06241751B1
公开(公告)日：2001-06-05
申请号：US09299455
申请日：1999-04-22
申请人： Carlton B. Morgan , Bradford E. Gliner , Kent W. Leyde , Thomas D. Lyster
发明人： Carlton B. Morgan , Bradford E. Gliner , Kent W. Leyde , Thomas D. Lyster
IPC分类号： A61N139
CPC分类号： A61N1/3943 , A61N1/39
摘要： A defibrillator having an energy storage capacitor network with multiple configurations selected according to patient impedance and desired energy level for delivery of an impedance-compensated defibrillation pulse is provided. The set of configurations may include series, parallel, and series/parallel combinations of energy storage capacitors within the energy storage capacitor network. The impedance-compensated defibrillation pulse may be delivered over an expanded range of energy levels while limiting the peak current to levels that are safe for the patient using configurations tailored for lower impedance patients and limiting the range of defibrillation pulse durations and providing adequate current levels for higher impedance patients. Configurations of the energy storage capacitor network may be readily added to extend the range of energy levels well above 200 joules.
摘要翻译：提供一种除颤器，其具有根据患者阻抗选择的多种配置的能量存储电容器网络和用于递送阻抗补偿除颤脉冲的期望能量水平。该组配置可以包括能量存储电容器网络内的能量存储电容器的串联，并联和串联/并联组合。阻抗补偿的除颤脉冲可以在能量水平的扩展范围内递送，同时将峰值电流限制到对于患者使用适合于较低阻抗患者的配置的安全性的水平，并且限制除颤脉冲持续时间的范围并提供足够的电流水平阻力较高的患者。可以容易地添加能量存储电容器网络的配置以扩展远高于200焦耳的能量范围。

5. 发明授权

US09643019B2 Neurological monitoring and alerts 有权
公开(公告)号：US09643019B2
公开(公告)日：2017-05-09
申请号：US13026961
申请日：2011-02-14
申请人： Jason A. Higgins , Michael Bland , Kent W. Leyde , W. Douglas Sheffield , John F. Harris , David M. Himes
发明人： Jason A. Higgins , Michael Bland , Kent W. Leyde , W. Douglas Sheffield , John F. Harris , David M. Himes
IPC分类号： A61B5/04 , A61N1/372 , A61B5/00 , A61N1/00 , A61N1/05
CPC分类号： A61N1/37258 , A61B5/4094 , A61N1/00 , A61N1/0529 , G16H40/67
摘要： A system for providing alerts of neurological events occurring in a human subject is provided. The system includes: a monitoring module adapted to detect and sample a neurological signal; an event detection module coupled to the monitoring module for detecting one or more types of predetermined reportable events based on the detected neurological signal; and an alert module coupled to the event detection module, wherein upon the detection of a reportable event by the event detection module, said alert module selects a first alert contact from a plurality of contacts contained in a contact list, and generates a first alert communication to the first alert contact.

6. 发明授权

US08849390B2 Processing for multi-channel signals 有权
公开(公告)号：US08849390B2
公开(公告)日：2014-09-30
申请号：US12649098
申请日：2009-12-29
申请人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
发明人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
IPC分类号： A61B5/04 , A61B5/0476 , A61B5/00
CPC分类号： A61B5/0476 , A61B5/4094
摘要： Method and apparatus for improved processing for multi-channel signals. In an exemplary embodiment, an anomaly metric is computed for a multi-channel signal over a time window. The magnitude of the anomaly metric may be used to determine whether an anomaly is present in the multi-channel signal over the time window. In an exemplary embodiment, the anomaly metric may be a condition number associated with the singular values of the multi-channel signal over the time window, as further adjusted by the number of channels to produce a data condition number. Applications of the anomaly metric computation include the scrubbing of signal archives for epileptic seizure detection/prediction/counter-prediction algorithm training, pre-processing of multi-channel signals for real-time monitoring of bio-systems, and boot-up and/or adaptive self-checking of such systems during normal operation.

7. 发明授权

US08786624B2 Processing for multi-channel signals 有权
标题翻译：多通道信号处理
公开(公告)号：US08786624B2
公开(公告)日：2014-07-22
申请号：US12792582
申请日：2010-06-02
申请人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
发明人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
IPC分类号： G06T11/20 , G09G5/02 , G06F19/00 , G06F17/18
CPC分类号： A61B5/0476 , A61B5/076 , A61B5/4094 , A61B2560/0271 , G06K9/00536 , G06T11/206
摘要： Method and apparatus for improved processing for multi-channel signals. In an exemplary embodiment, an anomaly metric is computed for a multi-channel signal over a time window. The magnitude of the anomaly metric may be used to determine whether an anomaly is present in the multi-channel signal over the time window. In an exemplary embodiment, the anomaly metric may be a condition number associated with the singular values of the multi-channel signal over the time window, as further adjusted by the number of channels to produce a data condition number. Applications of the anomaly metric computation include the scrubbing of signal archives for epileptic seizure detection/prediction/counter-prediction algorithm training, pre-processing of multi-channel signals for real-time monitoring of bio-systems, and boot-up and/or adaptive self-checking of such systems during normal operation.
摘要翻译：用于改善多通道信号处理的方法和装置。在示例性实施例中，针对时间窗口上的多信道信号计算异常度量。可以使用异常度量的大小来确定在时间窗口上的多通道信号中是否存在异常。在示例性实施例中，异常度量可以是与时间窗口上的多信道信号的奇异值相关联的条件数，如通过产生数据条件数的信道数进一步调整的。异常度量计算的应用包括擦除用于癫痫发作检测/预测/反预测算法训练的信号档案，用于实时监测生物系统的多通道信号的预处理，以及启动和/或这种系统在正常运行期间的自适应自检。

8. 发明申请

US20110213222A1 Communication Error Alerting in an Epilepsy Monitoring System 有权
标题翻译：癫痫监测系统通信错误警报
公开(公告)号：US20110213222A1
公开(公告)日：2011-09-01
申请号：US13070333
申请日：2011-03-23
申请人： Kent W. Leyde , John F. Harris
发明人： Kent W. Leyde , John F. Harris
IPC分类号： A61B5/00 , A61B5/04
CPC分类号： A61B5/0476 , A61B5/0006 , A61B5/0031 , A61B5/4094 , A61B2560/0271 , A61M5/14276 , A61N1/36082 , A61N1/37247 , A61N1/37258 , A61N1/37282 , G06F19/3418
摘要： Systems and methods for monitoring neurological signals in a patient are provided. The system includes: an implantable sensor adapted to collect neurological signals; an implantable assembly configured to sample the neurological signals collected by the sensor; and a rechargeable communication device external to the patient's body, said communication device configured to wirelessly communicate with the implantable assembly and to transmit a communication error alert to a caregiver advisory device in the event of a communication error between the implantable assembly and the communication device.
摘要翻译：提供了用于监测患者神经信号的系统和方法。该系统包括：适于收集神经信号的可植入传感器; 植入式组件，被配置为对由所述传感器收集的神经信号进行采样; 以及在患者身体外部的可充电通信设备，所述通信设备被配置为与可植入组件进行无线通信，并且在可植入组件和通信设备之间发生通信错误的情况下向通知设备发送通信错误警报。

9. 发明申请

US20110172554A1 Patient Entry Recording in an Epilepsy Monitoring System 审中-公开
标题翻译：癫痫监测系统中的患者进入记录
公开(公告)号：US20110172554A1
公开(公告)日：2011-07-14
申请号：US13070357
申请日：2011-03-23
申请人： Kent W. Leyde , John F. Harris
发明人： Kent W. Leyde , John F. Harris
IPC分类号： A61B5/048
CPC分类号： A61B5/0476 , A61B5/0006 , A61B5/0031 , A61B5/4094 , A61B2560/0271 , A61M5/14276 , A61N1/36082 , A61N1/37247 , A61N1/37258 , A61N1/37282 , G06F19/3418
摘要： Systems and methods for monitoring a patient are provided. The system includes: an implantable sensor adapted to collect neurological signals; an implantable assembly configured to sample the neurological signals collected by the sensor; and a rechargeable external assembly configured to wirelessly receive the sampled neurological signals from the implantable assembly, said external assembly being further configured to record a patient entry in response to receiving an input from the patient. The method includes: collecting neurological signals with a sensor implanted in the patient; sampling the neurological signals collected by the sensor with an implantable assembly implanted in the patient; and transmitting the sampled neurological signals from the implantable assembly to a rechargeable external assembly external to the patient; and recording a patient entry in response to receiving an input from the patient.
摘要翻译：提供了用于监测患者的系统和方法。该系统包括：适于收集神经信号的可植入传感器; 植入式组件，被配置为对由所述传感器收集的神经信号进行采样; 以及可充电外部组件，其被配置为从所述可植入组件无线地接收所述取样的神经信号，所述外部组件还被配置为响应于接收到来自所述患者的输入而记录患者入口。该方法包括：用植入患者的传感器收集神经信号; 用植入患者的可植入组件对由传感器收集的神经信号进行采样; 以及将所述取样的神经信号从所述可植入组件传输到患者外部的可再充电外部组件; 以及响应于从患者接收到输入而记录患者入口。

10. 发明申请

US20100302270A1 Processing for Multi-Channel Signals 有权
标题翻译：多通道信号处理
公开(公告)号：US20100302270A1
公开(公告)日：2010-12-02
申请号：US12792582
申请日：2010-06-02
申请人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
发明人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
IPC分类号： G06T11/20 , G09G5/02 , G06F19/00 , G06F17/18
CPC分类号： A61B5/0476 , A61B5/076 , A61B5/4094 , A61B2560/0271 , G06K9/00536 , G06T11/206
摘要： Method and apparatus for improved processing for multi-channel signals. In an exemplary embodiment, an anomaly metric is computed for a multi-channel signal over a time window. The magnitude of the anomaly metric may be used to determine whether an anomaly is present in the multi-channel signal over the time window. In an exemplary embodiment, the anomaly metric may be a condition number associated with the singular values of the multi-channel signal over the time window, as further adjusted by the number of channels to produce a data condition number. Applications of the anomaly metric computation include the scrubbing of signal archives for epileptic seizure detection/prediction/counter-prediction algorithm training, pre-processing of multi-channel signals for real-time monitoring of bio-systems, and boot-up and/or adaptive self-checking of such systems during normal operation.
摘要翻译：用于改善多通道信号处理的方法和装置。在示例性实施例中，针对时间窗口上的多信道信号计算异常度量。可以使用异常度量的大小来确定在时间窗口上的多通道信号中是否存在异常。在示例性实施例中，异常度量可以是与时间窗口上的多信道信号的奇异值相关联的条件数，如通过产生数据条件数的信道数进一步调整的。异常度量计算的应用包括擦除用于癫痫发作检测/预测/反预测算法训练的信号档案，用于实时监测生物系统的多通道信号的预处理，以及启动和/或这种系统在正常运行期间的自适应自检。

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