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1. 发明申请

US20150366608A1 MEDICAL DEVICE FOR SYMPATHETIC NERVE ABLATION WITH PRINTED COMPONENTS 审中-公开
标题翻译：与打印组件同步神经消融的医疗设备
公开(公告)号：US20150366608A1
公开(公告)日：2015-12-24
申请号：US14745311
申请日：2015-06-19
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： JAN WEBER , JEFFREY S. LINDQUIST , STEVEN R. LARSEN , ERIC M. PETERSEN , MARTIN R. WILLARD
IPC分类号： A61B18/14 , A61B18/04 , A61B18/16
摘要： A medical device for sympathetic nerve ablation may include an elongate shaft and an expandable member. A printed ablation electrode assembly may be disposed on an outer surface of the expandable member, the printed ablation electrode assembly including a positive electrical pathway and a ground electrical pathway printed directly on the outer surface of the expandable member. A temperature sensor may be printed directly on the outer surface of the expandable member. A method of manufacturing a medical device for sympathetic nerve ablation may include printing a conductive ink network directly on a surface of a polymeric balloon material in a flat configuration, printing at least one temperature sensor directly on the surface of the polymeric balloon material, forming the polymeric balloon material into an inflatable balloon, and attaching the inflatable balloon to an elongate catheter shaft.
摘要翻译：用于交感神经消融的医疗装置可以包括细长轴和可扩张构件。印刷的消融电极组件可以设置在可扩张构件的外表面上，印刷的消融电极组件包括正电通路和直接印在可扩张构件的外表面上的接地电路径。温度传感器可以直接印刷在可扩张构件的外表面上。用于交感神经消融的医疗装置的制造方法可以包括将导电油墨网络直接印刷在聚合物球囊材料的表面上，在平坦构型中，将至少一个温度传感器直接印刷在聚合物球囊材料的表面上，形成聚合气囊材料成为可充气球囊，并将可充气球囊附接到细长的导管轴上。

2. 发明申请

US20180221086A1 MEDICAL DEVICE BALLOON 审中-公开
公开(公告)号：US20180221086A1
公开(公告)日：2018-08-09
申请号：US15942863
申请日：2018-04-02
申请人： Boston Scientific Scimed, Inc.
发明人： JEFFREY S. LINDQUIST , CASS A. HANSON , PATRICK A. HAVERKOST , DANIEL J. HORN , MARTIN R. WILLARD , DEREK C. SUTERMEISTER
IPC分类号： A61B18/14 , A61B18/00
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/1465 , A61B2018/1467 , A61B2018/1475
摘要： Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter shaft. An expandable member may be coupled to the catheter shaft. The expandable member may be capable of shifting between a folded configuration and an expanded configuration. A plurality of flexible elements may be attached to the expandable member, with a plurality of electrode assemblies disposed on the flexible elements. The flexible elements may have a grooved substrate.

3. 发明申请

US20150297292A1 DEVICES AND METHODS FOR THERAPEUTIC HEAT TREATMENT 审中-公开
标题翻译：用于治疗热处理的装置和方法
公开(公告)号：US20150297292A1
公开(公告)日：2015-10-22
申请号：US14689363
申请日：2015-04-17
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： DEREK C. SUTERMEISTER , PATRICK A. HAVERKOST , TIMOTHY A. OSTROOT , CASS ALEXANDER HANSON , JEFFREY S. LINDQUIST , JOSEPH ALAN KRONSTEDT , JAN WEBER , JAMES M. ANDERSON , MARTIN R. WILLARD
IPC分类号： A61B18/14
摘要： Methods and devices (e.g., for nerve modulation) may include at least one thermistor and a balloon having a balloon wall. In one or more embodiments, the medical device is configured and arranged to transfer heat to the medical device surroundings. In one or more embodiments, the at least one thermistor is a portion of a thermistor array disposed on the balloon wall, the thermistor array including a plurality of thermistors and operatively engaged with a source of electric current. In one or more embodiments, the device includes at least one flexible circuit mounted on the outer surface of the expandable balloon, the at least one flexible circuit including at least one temperature-sensing device that includes at least one thermistor, wherein at least a portion of a conductive layer is electronically coupled to the thermistor, with the proviso that no electrode is associated with the conductive layer.
摘要翻译：方法和装置（例如，用于神经调制）可以包括至少一个热敏电阻和具有气球壁的球囊。在一个或多个实施例中，医疗装置被配置和布置成将热量传递到医疗装置周围环境。在一个或多个实施例中，所述至少一个热敏电阻是设置在气球壁上的热敏电阻阵列的一部分，热敏电阻阵列包括多个热敏电阻并且与电流源可操作地接合。在一个或多个实施例中，该装置包括安装在可膨胀气囊的外表面上的至少一个柔性电路，所述至少一个柔性电路包括至少一个包括至少一个热敏电阻的温度感测装置，其中至少一部分导电层的电极电耦合到热敏电阻，条件是没有电极与导电层相关联。

4. 发明申请

US20150105774A1 MEDICAL DEVICE BALLOON 有权
标题翻译：医疗器械气球
公开(公告)号：US20150105774A1
公开(公告)日：2015-04-16
申请号：US14513101
申请日：2014-10-13
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： JEFFREY S. LINDQUIST , CASS A. HANSON , PATRICK A. HAVERKOST , DANIEL J. HORN , MARTIN R. WILLARD , DEREK C. SUTERMEISTER
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/1465 , A61B2018/1467 , A61B2018/1475
摘要： Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter shaft. An expandable member may be coupled to the catheter shaft. The expandable member may be capable of shifting between a folded configuration and an expanded configuration. A plurality of flexible elements may be attached to the expandable member, with a plurality of electrode assemblies disposed on the flexible elements. The flexible elements may have a grooved substrate.
摘要翻译：公开了用于制造和使用医疗装置的医疗装置和方法。示例性医疗装置可以包括导管轴。可膨胀构件可以联接到导管轴。可膨胀构件可能能够在折叠构型和膨胀构型之间移动。多个柔性元件可以附接到可膨胀构件，多个电极组件设置在柔性元件上。柔性元件可以具有开槽衬底。

5. 发明申请

US20210000539A1 MEDICAL DEVICES WITH FLEXIBLE CIRCUIT ASSEMBLIES 有权
公开(公告)号：US20210000539A1
公开(公告)日：2021-01-07
申请号：US17031099
申请日：2020-09-24
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： PATRICK A. HAVERKOST , MARTIN R. WILLARD , DEREK C. SUTERMEISTER , JOEL N. GROFF , JEFFREY S. LINDQUIST , ROBERT N. SQUIRE
IPC分类号： A61B18/14 , A61F7/00 , A61F7/12 , H05K1/02
摘要： Medical devices for sympathetic nerve modulation are disclosed. An example medical device for sympathetic nerve modulation may include a catheter shaft having a distal region. An expandable member may be coupled to the distal region. A flexible circuit assembly may be attached to the expandable member. The flexible circuit assembly may include a first electrode strip, a second electrode strip, and a sensor strip disposed between the first electrode strip and the second electrode strip. The first electrode strip may include a first electrode. The second electrode strip may include a second electrode. The first electrode and the second electrode may define a pair of bipolar electrodes.

6. 发明申请

US20150265339A1 NERVE ABLATION DEVICES AND RELATED METHODS OF USE AND MANUFACTURE 审中-公开
标题翻译：神经消融装置及其相关使用和制造方法
公开(公告)号：US20150265339A1
公开(公告)日：2015-09-24
申请号：US14657622
申请日：2015-03-13
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： JEFFREY S. LINDQUIST , JOSEPH ZIELINSKI , MARK S. SMITH , KEVIN MARTIN , JOEL R. MUNSINGER
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00136 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511
摘要： A medical device for sympathetic nerve ablation includes a catheter shaft and an expandable member disposed on the catheter shaft. The balloon is configured to be able to shift between an unexpanded configuration and an expanded configuration. The medical device includes an elongate electrode assembly constructed as a flexible circuit and a protective bumper member. The elongate electrode assembly may have an outer edge and may be disposed on an outer surface of the balloon. The protective bumper member may cover at least a portion of the outer edge of the elongate electrode assembly.
摘要翻译：用于交感神经消融的医疗装置包括导管轴和布置在导管轴上的可扩张构件。气球被配置为能够在未扩展配置和扩展配置之间移动。医疗装置包括构造为柔性电路的细长电极组件和保护性保险杠构件。细长电极组件可以具有外边缘并且可以设置在气球的外表面上。保护保险杠构件可以覆盖细长电极组件的外边缘的至少一部分。

7. 发明申请

US20150190195A1 TEAR RESISTANT FLEX CIRCUIT ASSEMBLY 审中-公开
标题翻译：抗振动电路总成
公开(公告)号：US20150190195A1
公开(公告)日：2015-07-09
申请号：US14590667
申请日：2015-01-06
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： CASS A. HANSON , DEREK C. SUTERMEISTER , TIMOTHY A. OSTROOT , ROBERT N. SQUIRE , JAMES M. ANDERSON , MARTIN R. WILLARD , PATRICK A. HAVERKOST , JAN WEBER , JEFFREY S. LINDQUIST , DANIEL J. HORN
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00059 , A61B2018/0016 , A61B2018/0022 , A61B2018/00434 , A61B2018/00505 , A61B2018/00577
摘要： A medical device for sympathetic nerve ablation may include a catheter shaft, an expandable member disposed on or coupled to the catheter shaft, and a plurality of elongate electrode assemblies each constructed as a flexible circuit having a plurality of layers. The expandable member may be configured to shift between an unexpanded configuration and an expanded configuration. The plurality of electrode assemblies may be disposed on an outer surface of the expandable member. Each of the plurality of electrode assemblies may include enhanced tear resistance properties such as through the inclusion of a reinforcement structure with one or more of the layers of the electrode assemblies.
摘要翻译：用于交感神经消融的医疗装置可以包括导管轴，设置在导管轴上或联接到导管轴上的可扩张构件，以及多个细长电极组件，每个构造为具有多个层的柔性电路。可扩展构件可以被配置为在未膨胀构型和膨胀构型之间移动。多个电极组件可以设置在可扩张构件的外表面上。多个电极组件中的每一个可以包括增强的抗撕裂特性，例如通过包括具有电极组件的一个或多个层的加强结构。

8. 发明申请

US20130172872A1 DEVICE AND METHODS FOR NERVE MODULATION USING A NOVEL ABLATION CATHETER WITH POLYMERIC ABLATIVE ELEMENTS 有权
标题翻译：使用新型吸收管与聚合物元素进行神经调制的装置和方法
公开(公告)号：US20130172872A1
公开(公告)日：2013-07-04
申请号：US13711231
申请日：2012-12-11
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： RAJ SUBRAMANIAM , ZAYA TUN , DANIEL J. HORN , DEREK C. SUTERMEISTER , JAMES M. ANDERSON , JEFFREY S. LINDQUIST , KENT D. HARRISON
IPC分类号： A61M25/10 , A61B18/18
CPC分类号： A61B18/00 , A61B18/1492 , A61B18/18 , A61B2018/00077 , A61B2018/00083 , A61B2018/00136 , A61B2018/0016 , A61B2018/00166 , A61B2018/0022 , A61B2018/00238 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00791 , A61B2018/1435 , A61B2018/147 , A61B2018/1472 , A61B2218/002 , A61M25/10
摘要： The disclosure pertains to an intravascular catheter for nerve modulation, comprising an elongate member having a proximal end and a distal end, a balloon having a lumen and a balloon wall, the balloon wall comprising RF permeable sections and non-electrically conductive sections, an electrode disposed within the balloon and extending distally to the furthest distal RF permeable section. The RF permeable sections may comprise a plurality of RF permeable windows, each window having a greater circumferential dimension than an axial dimension. The intravascular system is suited for modulation of renal nerves.
摘要翻译：本发明涉及用于神经调节的血管内导管，包括具有近端和远端的细长构件，具有内腔和球囊壁的球囊，所述球囊壁包括RF可渗透部分和非导电部分，电极设置在球囊内并向远端延伸到最远的远端可透射部分。 RF透射部分可以包括多个RF可透过窗口，每个窗口具有比轴向尺寸更大的周向尺寸。血管内系统适用于肾神经的调节。

9. 发明申请

US20150342673A1 NERVE MODULATION DEVICES WITH COOLING CAPABILITIES 审中-公开
标题翻译：具有冷却能力的神经调制装置
公开(公告)号：US20150342673A1
公开(公告)日：2015-12-03
申请号：US14723000
申请日：2015-05-27
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： ROBERT N. SQUIRE , ADAM J. ROYER , DEREK C. SUTERMEISTER , CASS A. HANSON , JEFFREY S. LINDQUIST
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00029 , A61B2018/0016 , A61B2018/0022 , A61B2018/00226 , A61B2018/00232 , A61B2018/00285 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/1407 , A61B2018/1435 , A61B2018/1465
摘要： Medical devices and methods and making and using medical devices are disclosed. An example medical device may include an elongate shaft having a distal region. An expandable member may be coupled to the distal region. The expandable member may be capable of shifting between a first configuration and an expanded configuration. The expandable member may have a distal portion, a proximal portion, and a body portion disposed between the distal portion and the proximal portion. The body portion may have a projection formed therein that projects radially outward from the body portion. A flexible electrode assembly may be coupled to the projection.
摘要翻译：公开了医疗装置和方法以及制造和使用医疗装置。示例性医疗装置可以包括具有远侧区域的细长轴。可扩张构件可以联接到远端区域。可扩展构件可以能够在第一构造和扩展构型之间移动。可扩张构件可以具有远侧部分，近端部分和设置在远端部分和近端部分之间的主体部分。主体部分可以具有形成在其中的从主体部分径向向外突出的突起。柔性电极组件可以联接到突起。

10. 发明申请

US20150190194A1 SYMPATHETIC NERVE ABLATION DEVICES WITH AN EXPANSION-LIMITING MEMBER 审中-公开
标题翻译：具有扩张限制性成员的同步神经消融装置
公开(公告)号：US20150190194A1
公开(公告)日：2015-07-09
申请号：US14589516
申请日：2015-01-05
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： JAN WEBER , MARTIN R. WILLARD , JEFFREY S. LINDQUIST
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2017/00526 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00791 , A61B2018/1465
摘要： Medical devices for sympathetic nerve modulation are disclosed. An example medical device for sympathetic nerve modulation may include a catheter shaft having a distal region. A compliant balloon may be coupled to the distal region. A flexible circuit assembly may be coupled to the compliant balloon. The flexible circuit assembly may include one or more electrodes. An expansion-limiting member may be coupled to the compliant balloon.
摘要翻译：公开了用于交感神经调节的医疗装置。用于交感神经调节的示例医疗装置可以包括具有远端区域的导管轴。顺应性球囊可以联接到远侧区域。柔性电路组件可以耦合到柔性气囊。柔性电路组件可以包括一个或多个电极。膨胀限制构件可以联接到顺应性球囊。

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