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    • 4. 发明申请
    • Method of using differential measurement in two or more channels to improve sensitivity
    • 在两个或多个通道中使用差分测量以提高灵敏度的方法
    • US20080038711A1
    • 2008-02-14
    • US11500626
    • 2006-08-08
    • Bo U. CurryRene P. Helbing
    • Bo U. CurryRene P. Helbing
    • C12Q1/00C12Q1/68G06F19/00
    • G01N33/582G01N33/558
    • A method to calibrate measurements of a test analyte in a test sample including measuring at least one test-light level responsive to reactions of at least one reagent group and at least one reactive test analyte in the test sample and measuring at least one control-light level responsive to reactions of at least one reagent group and at least one control analyte in a control sample. Each control analyte is a known amount of at least one reactive test analyte. The method further includes determining a presence of the reactive test analyte in the test sample based on the measured test-light levels and control-light levels. The reagent group and the reactive test analyte react by attaching to each other.
    • 校准测试样品中测试分析物的测量的方法,包括测量响应于至少一种试剂组和至少一种反应性测试分析物在测试样品中的反应的至少一种测试光级,并测量至少一种对照光 响应于对照样品中至少一个试剂组和至少一个对照分析物的反应。 每个对照分析物是已知量的至少一种反应性测试分析物。 所述方法还包括基于测量的测试光水平和控制光水平来确定测试样品中反应性测试分析物的存在。 试剂组和反应性试验分析物通过彼此连接而反应。
    • 6. 发明授权
    • Ferroelectric liquid crystal light doubler with temperature and voltage controlled tilt angle
    • US06198523B1
    • 2001-03-06
    • US09429246
    • 1999-10-28
    • Rene P. Helbing
    • Rene P. Helbing
    • C09K1902
    • G02B5/3025G02F1/133382G02F1/13471G02F1/141G09G3/36G09G3/3614G09G3/3651G09G2300/0809G09G2320/041G09G2320/0606G09G2320/066
    • A ferroelectric liquid crystal-based switchable half-wave plate with improved alignment control, a ferroelectric liquid crystal-based light valve system with improved contrast control, and a method of improving contrast in a ferroelectric liquid crystal-based light valve system. The switchable half-wave plate with improved alignment control includes a layer of ferroelectric liquid crystal material sandwiched between a first transparent electrode and a second transparent electrode. The switchable half-wave plate also includes an electric field direction switching circuit configured to switch the electric field across the liquid crystal material between the forward direction and the reverse direction in response to a control signal. The switchable half-wave plate additionally includes an electric field magnitude control circuit to adjust the tilt angle in response to a signal received at a alignment control signal input. The ferroelectric liquid crystal-based light valve system according to the invention includes at least one ferroelectric liquid crystal-based spatial light modulator, an analyzer having a direction of minimum transmissivity, a ferroelectric liquid crystal-based switchable half-wave plate, and an adjustable voltage source. The voltage source is configured to adjust the magnitude of the electric field in at least one of the forward direction and reverse direction as the output voltage level is adjusted in response to a user interface or a light intensity sensor and a feedback circuit. The method of improving contrast in a ferroelectric light valve system according to the invention includes providing a ferroelectric liquid crystal-based spatial light modulator, an analyzer, a ferroelectric liquid crystal based switchable half-wave plate, and a video signal. In response to the video signal, a pixel electric field across each of the plurality of pixels is switched. Also an electric field across the switchable half-wave plate is periodically switched and the magnitude of the half-wave plate electric field is adjusted to align one of the first and the second half-wave plate director angles with one of the first and the second modulator director angles.