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1. 发明申请

US20170071740A1 SYSTEMS AND METHODS FOR DEPLOYING A CARDIAC ANCHOR 审中-公开
标题翻译：用于分配心脏锚的系统和方法
公开(公告)号：US20170071740A1
公开(公告)日：2017-03-16
申请号：US15259375
申请日：2016-09-08
申请人： BioVentrix, Inc.
发明人： Kevin Van Bladel , Meir Moshe , Michael S. Dana
IPC分类号： A61F2/24 , A61M25/00 , A61M25/01 , A61B17/34
CPC分类号： A61F2/2487 , A61B17/0401 , A61B17/3468 , A61B2017/00243 , A61B2017/00323 , A61B2017/0409 , A61B2017/0411 , A61B2017/0417 , A61B2017/0464 , A61F2002/249 , A61M25/0074 , A61M25/0082 , A61M25/0136 , A61M2025/015
摘要： A heart implant alignment and delivery device includes an elongate body having an opening that is disposed near a distal end of the elongate body. The opening is configured so that a heart implant is positionable within the opening with the heart implant exposed to a surrounding environment and so that the heart implant is substantially aligned with the distal end of the elongate body. The device also includes an implant reposition member, such as a cable, that is releasably coupleable with the heart implant and that is operationally coupled with the elongate body so that a first operation of the implant reposition member causes the heart implant to be retractably deployed from the opening of the elongate body. The first operation of the implant reposition member may be effected via a handle mechanism that is attached to a proximal end of the elongate body.
摘要翻译：心脏植入物对准和递送装置包括细长体，其具有设置在细长体的远端附近的开口。开口构造成使得心脏植入物可定位在开口内，其中心脏植入物暴露于周围环境，并且使得心脏植入物基本上与细长体的远端对准。该装置还包括植入物重新定位构件，例如电缆，其可释放地与心脏植入物联接并且可操作地与细长主体联接，使得植入物重新定位构件的第一操作使得心脏植入物可从细长体的开口。植入物重新定位构件的第一操作可以通过附接到细长体的近端的手柄机构来实现。

2. 发明申请

US20160051240A1 TISSUE PROTECTING DEVICES FOR TREATMENTOF CONGESTIVE HEART FAILURE AND OTHER CONDITIONS 审中-公开
标题翻译：用于治疗心绞痛及其他症状的组织保护装置
公开(公告)号：US20160051240A1
公开(公告)日：2016-02-25
申请号：US14835608
申请日：2015-08-25
申请人： BioVentrix, Inc.
发明人： Kevin Van Bladel , Aaron Weiss , Lon Annest , Gilbert Mata, JR.
IPC分类号： A61B17/00 , A61F2/24
摘要： According to one embodiment, a protective device for use in congestive heart failure treatments, and other treatments, includes a control mechanism, an elongate shaft, and a protective plate. The control mechanism is coupled with a proximal end of the elongate shaft and the protective plate is pivotably coupled with a distal end of the elongate shaft. The elongate shaft enables the protective plate to be inserted within a body and navigated distally of a heart wall. The protective plate has a relatively wide and thin body portion and is pivotable relative to the elongate shaft by operation of the control mechanism. Pivoting and/or navigating of the protective plate within the body allows the protective plate to be positioned adjacent the heart wall to shield body organs or tissue surrounding the heart wall from being damaged by surgical instruments inserted through the heart wall.
摘要翻译：根据一个实施例，用于充血性心力衰竭治疗的保护装置和其他治疗包括控制机构，细长轴和保护板。控制机构与细长轴的近端连接，并且保护板与细长轴的远端可枢转地联接。细长轴使得保护板能够插入到身体内并在心脏壁的远端导航。保护板具有相对宽且薄的主体部分，并且通过控制机构的操作可相对于细长轴枢转。在身体内的保护板的枢转和/或导航允许保护板邻近心脏壁定位，以屏蔽围绕心脏壁的身体器官或组织免受通过心脏壁插入的外科器械的损伤。

3. 发明申请

US20130090523A1 REMOTE PERICARDIAL HEMOSTASIS FOR VENTRICULAR ACCESS AND RECONSTRUCTION OR OTHER ORGAN THERAPIES 有权
标题翻译：用于心室通道和重建或其他器官治疗的远端周围血栓形成
公开(公告)号：US20130090523A1
公开(公告)日：2013-04-11
申请号：US13632103
申请日：2012-09-30
申请人： BIOVENTRIX, INC.
发明人： Kevin Van Bladel , Lon Annest , John Stiggelbout , Rovil Arcia
IPC分类号： A61B19/00
CPC分类号： A61F2/2487 , A61B17/00 , A61B17/00234 , A61B17/0057 , A61B17/0401 , A61B17/0485 , A61B17/12013 , A61B17/3417 , A61B17/3478 , A61B34/70 , A61B2017/00243 , A61B2017/00323 , A61B2017/00561 , A61B2017/0406 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/042 , A61B2017/0422 , A61B2017/0464 , A61B2017/0496 , A61B2017/22038 , A61B2017/22065 , A61B2017/2215 , A61B2017/306 , A61B2017/3458 , A61B2017/3488 , A61B2018/1425 , A61M29/02
摘要： Embodiments described herein provide devices, systems, and methods that reduce the distance between two locations in tissue, often for treatment of congestive heart failure. For example, an anchor of an implant system may, when the implant system is fully deployed, reside within the right ventricle in engagement with the ventricular septum. The anchor may be deployed into the heart through a working lumen of a minimally invasive access tool. The minimally invasive access tool may have a plurality of grippers near a distal end of the working lumen. The grippers may engage epicardial tissue of the heart and may be moved radially inwardly relative so as to provide stabilization of the epicardial tissue and/or hemostasis near an access site where the anchor is inserted through the epicardium. The minimally invasive access tool may minimize blood loss from the access site and improve anchor implant processes.
摘要翻译：本文描述的实施例提供减少组织中两个位置之间距离的装置，系统和方法，通常用于治疗充血性心力衰竭。例如，当植入物系统完全展开时，植入物系统的锚固件可以驻留在与心室隔膜接合的右心室内。锚可以通过微创入侵工具的工作内腔部署到心脏中。微创入口工具可以在工作腔的远端附近具有多个夹持器。夹持器可以接合心脏的心外膜组织，并且可相对于径向向内移动，以便提供靠近插入心外膜的进入部位的心外膜组织和/或止血的稳定性。微创入侵工具可以使来自接入部位的血液丢失最小化并改善锚固植入过程。

4. 发明授权

US11559212B2 Cardiac tissue penetrating devices, methods, and systems for treatment of congestive heart failure and other conditions 有权
公开(公告)号：US11559212B2
公开(公告)日：2023-01-24
申请号：US16413247
申请日：2019-05-15
申请人： BioVentrix, Inc.
发明人： Kevin Van Bladel , Meir Moshe , Lon Annest
IPC分类号： A61B5/0215 , A61F2/24 , A61B17/04 , A61B1/005 , A61B5/06 , A61B17/00 , A61B17/06
摘要： According to one embodiment, a tissue penetrating device includes an elongate shaft having a proximal end, a distal end, and a lumen extending there between. A first needle is disposed within the lumen of the elongate shaft and is extendable therefrom between a first configuration and a second configuration. In the first configuration, the first needle is disposed within the elongate shaft's lumen and is substantially aligned with an axis of the lumen. In the second configuration, the first needle extends distally of the elongate shaft's distal end and bends away from the lumen's axis. A second needle is disposed within a lumen of the first needle and is extendable therefrom when the first needle is positioned in the first configuration and when the first needle is positioned in the second configuration. The second needle may be extended from the first needle to penetrate tissue of a patient.

5. 发明授权

US11478353B2 Percutaneous arterial access to position trans-myocardial implant devices and methods 有权
公开(公告)号：US11478353B2
公开(公告)日：2022-10-25
申请号：US15418152
申请日：2017-01-27
申请人： BioVentrix, Inc.
发明人： Kevin Van Bladel , Serjan Nikolic , Lon Annest , Rovil Arcia
IPC分类号： A61F2/24 , A61B17/04 , A61B17/00
摘要： A system for treating a heart includes a catheter that is advanceable into a chamber of the heart and that is repositionable within the chamber between a septal wall and an external wall to enable penetration of the septal and external walls via a needle that is disposed within a lumen of the catheter. A first guidewire is deliverable through the penetration of the septal wall so that a distal end of the first guidewire is disposed within another chamber of the heart. A second guidewire is deliverable through the penetration of the external wall so that a distal end of the second guidewire is disposed externally of the external wall. The first guidewire is connectable to the second guidewire to join or form a path within the chamber that extends between the septal wall and the external wall.

6. 发明申请

US20220000622A1 TRANS-CATHETER VENTRICULAR RECONSTRUCTION STRUCTURES, METHODS, AND SYSTEMS FOR TREATMENT OF CONGESTIVE HEART FAILURE AND OTHER CONDITIONS 有权
公开(公告)号：US20220000622A1
公开(公告)日：2022-01-06
申请号：US17350668
申请日：2021-06-17
申请人： BioVentrix, Inc.
发明人： Kevin Van Bladel , Lon Annest , Murray Sheldon , Ernie Heflin , Andrew Wechsler , John Stiggelbout , Rovil Arcia , John Bower
IPC分类号： A61F2/24 , A61B34/00 , A61B17/00 , A61M29/02 , A61B17/04 , A61B17/12
摘要： Embodiments described herein include devices, systems, and methods for reducing the distance between two locations in tissue. In one embodiment, an anchor may reside within the right ventricle in engagement with the septum. A tension member may extend from that anchor through the septum and an exterior wall of the left ventricle to a second anchor disposed along a surface of the heart. Perforating the exterior wall and the septum from an epicardial approach can provide control over the reshaping of the ventricular chamber. Guiding deployment of the implant from along the epicardial access path and another access path into and through the right ventricle provides control over the movement of the anchor within the ventricle. The joined epicardial pathway and right atrial pathway allows the tension member to be advanced into the heart through the right atrium and pulled into engagement along the epicardial access path.

7. 发明授权

US11051941B2 Over-the-wire cardiac implant delivery system for treatment of CHF and other conditions 有权
公开(公告)号：US11051941B2
公开(公告)日：2021-07-06
申请号：US14930608
申请日：2015-11-02
申请人： BIOVENTRIX, INC.
发明人： Lon Annest , Murray Sheldon , Kevin Van Bladel , Ernie Heflin , William Butler , Andrew Wechsler , John Bower , Rovil Arcia
IPC分类号： A61F2/24 , A61B34/00 , A61B17/00 , A61M29/02 , A61B17/04 , A61B17/12 , A61B17/221 , A61B17/22 , A61B17/30 , A61B17/34 , A61B18/14
摘要： Medical devices, systems, and methods reduce the distance between two locations in tissue in a minimally invasive manner, often for treatment of congestive heart failure. In one embodiment, an anchor of an implant system may, when the implant system is fully deployed, reside within the right ventricle in engagement with the ventricular septum. A tension member may extend from that anchor through the septum and an exterior wall of the left ventricle to a second anchor disposed along an epicardial surface of the heart. Deployment of the anchor within the right ventricle may be performed by inserting a guidewire through the septal wall into the right ventricle. The anchor may be inserted into the right ventricle over the guidewire and through a lumen of a delivery catheter. Delivering the anchor over the guidewire may provide improved control in the delivery and placement of the anchor within the right ventricle.

8. 发明申请

US20200163664A1 CARDIAC TISSUE ANCHORING DEVICES, METHODS, AND SYSTEMS FOR TREATMENT OF CONGESTIVE HEART FAILURE AND OTHER CONDITIONS 审中-公开
公开(公告)号：US20200163664A1
公开(公告)日：2020-05-28
申请号：US16776751
申请日：2020-01-30
申请人： BioVentrix, Inc.
发明人： Meir Moshe , Lon S. Annest , Kevin Van Bladel
IPC分类号： A61B17/04
摘要： A heart tissue gripping device may include a body portion, an elongate shaft, and a tissue gripping member that is attached to the distal end of the elongate shaft. The tissue gripping member being may be positioned adjacent a heart surface by insertion through an incision in the body. The tissue gripping member may releasably attach to tissue of the heart surface to facilitate a surgical instrument in performing one or more procedures. A coupling of the tissue gripping member may releasably attach the surgical device to the tissue gripping member to allow the device to access the tissue of the heart surface.

9. 发明授权

US10575953B2 Heart anchor positioning devices, methods, and systems for treatment of congestive heart failure and other conditions 有权
公开(公告)号：US10575953B2
公开(公告)日：2020-03-03
申请号：US14473556
申请日：2014-08-29
申请人： BioVentrix, Inc.
发明人： Kevin Van Bladel , Lon Annest , Ernest Heflin , Gilbert Mata , Lawrence Crainich , Brian LaRose
IPC分类号： A61F2/24
摘要： According to one embodiment, a heart anchor tensioning device includes a main body and an elongate shaft. A tension member or tether may be inserted through a lumen of the elongate shaft to allow the shaft to be advanced over the tension member and within a body while the main body is positioned outside of the body. The device also includes an anchor coupling mechanism that is configured to engage a heart anchor and move the heart anchor into engagement with a first wall of the heart. The anchor coupling mechanism is able to lock the heart anchor to inhibit proximal movement of the heart anchor along the tension member. The device further includes a tension indicating mechanism that provides an indication of a force being applied to the heart anchor by the device.

10. 发明授权

US10179049B2 Trans-catheter ventricular reconstruction structures, methods, and systems for treatment of congestive heart failure and other conditions 有权
公开(公告)号：US10179049B2
公开(公告)日：2019-01-15
申请号：US15495842
申请日：2017-04-24
申请人： BioVentrix, Inc.
发明人： Kevin Van Bladel , Lon Annest , Murray Sheldon , Ernie Heflin , Andrew Wechsler , John Stiggelbout , Rovil Arcia , John Bower
IPC分类号： A61F17/00 , A61F2/24 , A61B17/00 , A61B17/04 , A61B17/12 , A61B17/22
摘要： Embodiments described herein include devices, systems, and methods for reducing the distance between two locations in tissue. In one embodiment, an anchor may reside within the right ventricle in engagement with the septum. A tension member may extend from that anchor through the septum and an exterior wall of the left ventricle to a second anchor disposed along a surface of the heart. Perforating the exterior wall and the septum from an epicardial approach can provide control over the reshaping of the ventricular chamber. Guiding deployment of the implant from along the epicardial access path and another access path into and through the right ventricle provides control over the movement of the anchor within the ventricle. The joined epicardial pathway and right atrial pathway allows the tension member to be advanced into the heart through the right atrium and pulled into engagement along the epicardial access path.

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