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1. 发明申请

US20050214413A1 Methods and compositions for modified release of nutritional supplements 审中-公开
标题翻译：营养补充剂修饰释放的方法和组合物
公开(公告)号：US20050214413A1
公开(公告)日：2005-09-29
申请号：US11072005
申请日：2005-03-03
申请人： Bill McAnalley , Eileen Vennum , Shayne McAnalley , C. Koepke , Josh Edwards
发明人： Bill McAnalley , Eileen Vennum , Shayne McAnalley , C. Koepke , Josh Edwards
IPC分类号： A23K1/175 , A23L1/00 , A23L1/22 , A23L1/30
CPC分类号： A23K20/00 , A23K20/20 , A23K40/20 , A23L27/72 , A23L33/10 , A23L33/105 , A23L33/145 , A23L33/15 , A23L33/175 , A23P10/30
摘要： The present invention relates to the modified release of nutritional supplements by combining one or more isolated and purified long-chain polysaccharides and one or more nutritional supplements selected from anti-oxidants, vitamins, minerals, amino acids, nucleic acids, mixtures and combinations thereof, wherein the supplement is compressed at a pressure greater that 100 psi.
摘要翻译：本发明涉及通过组合一种或多种分离和纯化的长链多糖和选自抗氧化剂，维生素，矿物质，氨基酸，核酸，其混合物和组合的一种或多种营养补充剂来调节营养补充剂的释放，其中补充物在大于100psi的压力下被压缩。

2. 发明申请

US20050087452A1 Antioxidant sensor, methods and compositions 审中-公开
标题翻译：抗氧化剂传感器，方法和组成
公开(公告)号：US20050087452A1
公开(公告)日：2005-04-28
申请号：US10918704
申请日：2004-08-16
申请人： Bill McAnalley , Eileen Vennum , Shayne McAnalley , C. Koepke
发明人： Bill McAnalley , Eileen Vennum , Shayne McAnalley , C. Koepke
IPC分类号： A61K31/353 , A61K31/355 , A61K31/7048 , A61K36/24 , A61K36/82 , A61K36/87 , C12Q1/00 , G01F1/64 , G01N27/26 , G01N33/50
CPC分类号： A61K31/355 , A61K31/353 , A61K31/7048 , A61K36/24 , A61K36/82 , A61K36/87 , G01N33/1806 , Y10S514/904 , Y10T436/142222 , A61K2300/00
摘要： The present invention includes an apparatus and method for detecting directly the antioxidant activity of both lipophilic and lipophobic anti-oxidants that uses an oxygen radical sensitive sensor in fluid communication with a sample in a solvent/water/surfactant mixture; wherein the oxygen radical sensitive sensor concurrently detects both lipophilic and lipophobic anti-oxidants in the solvent/water/surfactant mixture.
摘要翻译：本发明包括一种用于直接检测亲脂性和疏脂性抗氧化剂的抗氧化活性的装置和方法，其使用在溶剂/水/表面活性剂混合物中与样品流体连通的氧自由基敏感传感器; 其中氧自由基敏感传感器同时检测溶剂/水/表面活性剂混合物中的亲脂性和疏脂性抗氧化剂。

3. 发明申请

US20050048143A1 Antioxidant compositions and methods thereto 有权
标题翻译：抗氧化剂组合物及其方法
公开(公告)号：US20050048143A1
公开(公告)日：2005-03-03
申请号：US10648047
申请日：2003-08-26
申请人： Bill McAnalley , Eileen Vennum , Shayne McAnalley , C. Koepke
发明人： Bill McAnalley , Eileen Vennum , Shayne McAnalley , C. Koepke
IPC分类号： A61K31/353 , A61K31/355 , A61K31/7048 , A61K36/24 , A61K36/82 , A61K36/87 , A61K35/78
CPC分类号： A61K31/355 , A61K31/353 , A61K31/7048 , A61K36/24 , A61K36/82 , A61K36/87 , G01N33/1806 , Y10S514/904 , Y10T436/142222 , A61K2300/00
摘要： The present invention provides a performance assay that measures the total antioxidant activity of a composition using oxygen uptake in contrast to prior art methods that measure antioxidant capacity by indirectly measuring degradation of a fluorescent compound by following the disappearance of fluorescence. Using the performance antioxidant assay of the present invention, an antioxidant composition having synergistic activity is provided by the present inventors that includes flavonoids such as the flavonol quercetin, mixed tocopherols or tocotrienols, grape skin extract, green tea extract and bush plum. The antioxidant activity of the present composition exceeds 6,000 micromoles Trolox equivalent units per gram using the present invention.
摘要翻译：本发明提供一种性能测定法，其与通过间接测量荧光化合物的降解以测量抗氧化能力的现有技术方法相比，测量组合物使用氧吸收的总抗氧化活性。使用本发明的性能抗氧化剂测定法，本发明人提供了具有协同活性的抗氧化剂组合物，其包括类黄酮如黄酮醇槲皮素，混合生育酚或生育三烯酚，葡萄皮提取物，绿茶提取物和布梅。使用本发明，本发明组合物的抗氧化活性超过6,000微摩尔Trolox当量单位/克。

4. 发明申请

US20090036413A1 Compositions, uses, and method of making wound care products from naturally occurring food ingredients 审中-公开
标题翻译：从天然食品成分制作伤口护理产品的组合物，用途和方法
公开(公告)号：US20090036413A1
公开(公告)日：2009-02-05
申请号：US12220854
申请日：2008-07-29
申请人： Shayne McAnalley , Bill McAnalley , Erik Aguayo
发明人： Shayne McAnalley , Bill McAnalley , Erik Aguayo
IPC分类号： A61K31/60 , A61K31/11 , A61P17/02
CPC分类号： A61L15/20 , A61K9/0014 , A61K9/006 , A61K9/06 , A61L15/34 , A61L15/60
摘要： Rationally designed wound care products made entirely of naturally occurring food ingredients that can be standardized and made available for the mass market using good manufacturing practice (GMP) guidelines, optionally, a safe food additive can be added. These products: are safe and effective; have an osmotic pressure compatible with optimal healing; are buffered to maintain optimal pH throughout the healing process; provide a protective barrier from further irritation and insult; control bacteria, viruses and fungi found in the skin and mucosa; nourish wounds; control excessive prolonged inflammation and thereby minimize scarring; minimize allergenic and irritation potential; are easy to use or apply; pass the preservative challenge test required for products intended for multiple use; contain fragrant essential oils to take advantage of the benefits provided by aromatherapy; can be individually optimized based on the diet of an individual or group of people.
摘要翻译：合理设计的伤口护理产品完全由完全由天然存在的食品成分制成，可以使用良好的制造实践（GMP）指南（可选地，安全的食品添加剂）可以标准化并提供给大众市场。这些产品：安全有效; 具有与最佳愈合相适应的渗透压; 被缓冲以在愈合过程中保持最佳pH; 提供防止进一步刺激和侮辱的保护屏障; 控制皮肤和粘膜中发现的细菌，病毒和真菌; 滋养伤口控制过度延长的炎症，从而减少瘢痕形成; 尽量减少过敏和刺激的潜力; 易于使用或应用; 通过旨在多用途的产品所需的防腐剂挑战测试; 含有芳香精油，以利用芳香疗法提供的好处; 可以根据个人或一群人的饮食进行单独优化。

5. 发明授权

US08231914B2 Antioxidant compositions and methods thereto 有权
标题翻译：抗氧化剂组合物及其方法
公开(公告)号：US08231914B2
公开(公告)日：2012-07-31
申请号：US13170769
申请日：2011-06-28
申请人： Bill H. McAnalley , Eileen P. Vennum , Shayne McAnalley , C. Michael Koepler
发明人： Bill H. McAnalley , Eileen P. Vennum , Shayne McAnalley , C. Michael Koepler
IPC分类号： A61K36/82 , A61K31/355
CPC分类号： A61K31/355 , A61K31/353 , A61K31/7048 , A61K36/24 , A61K36/82 , A61K36/87 , G01N33/1806 , Y10S514/904 , Y10T436/142222 , A61K2300/00
摘要： The present invention provides a performance assay that measures the total antioxidant activity of a composition using oxygen uptake in contrast to prior art methods that measure antioxidant capacity by indirectly measuring degradation of a fluorescent compound by following the disappearance of fluorescence. Using the performance antioxidant assay of the present invention, an antioxidant composition having synergistic activity is provided by the present inventors that includes flavonoids such as the flavonol quercetin, mixed tocopherols or tocotrienols, grape skin extract, green tea extract and bush plum. The antioxidant activity of the present composition exceeds 6,000 micromoles Trolox equivalent units per gram using the present invention.
摘要翻译：本发明提供一种性能测定法，其与通过间接测量荧光化合物的降解以测量抗氧化能力的现有技术方法相比，测量组合物使用氧吸收的总抗氧化活性。使用本发明的性能抗氧化剂测定法，本发明人提供了具有协同活性的抗氧化剂组合物，其包括类黄酮如黄酮醇槲皮素，混合生育酚或生育三烯酚，葡萄皮提取物，绿茶提取物和布梅。使用本发明，本发明组合物的抗氧化活性超过6,000微摩尔Trolox当量单位/克。

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