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1. 发明授权

US08865752B2 Cytochrome P450 inhibitors and uses thereof 有权
标题翻译：细胞色素P450抑制剂及其用途
公开(公告)号：US08865752B2
公开(公告)日：2014-10-21
申请号：US13935517
申请日：2013-07-04
申请人： Bijoy Panicker , Dong Sung Lim , Rama K. Mishra , Lambertus J. W. M. Oehlen , James G. Tarrant , Xiaokang Zhu , Dawoon Jung
发明人： Bijoy Panicker , Dong Sung Lim , Rama K. Mishra , Lambertus J. W. M. Oehlen , James G. Tarrant , Xiaokang Zhu , Dawoon Jung
IPC分类号： C07D417/12 , A61K31/428 , C07D417/06 , C07D417/04 , C07D417/14
CPC分类号： C07D417/06 , C07D417/04 , C07D417/12 , C07D417/14
摘要： The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.
摘要翻译：本发明提供具有一般结构式（I）的化合物及其药学上可接受的衍生物，如本文中一般和本类和亚类所述，并且另外提供其药物组合物，以及用于治疗任何一种涉及纤维化和增殖的病症或疾病，其中抗纤维化或抗增殖活性是有益的。

2. 发明授权

US08513291B2 Cytochrome P450 inhibitors and uses thereof 有权
标题翻译：细胞色素P450抑制剂及其用途
公开(公告)号：US08513291B2
公开(公告)日：2013-08-20
申请号：US13700730
申请日：2011-06-01
申请人： Bijoy Panicker , Lambertus J. W. M. Oehlen , James G. Tarrant , Dong Sung Lim , Xiaokang Zhu , Dawoon Jung , Rama K. Mishra
发明人： Bijoy Panicker , Lambertus J. W. M. Oehlen , James G. Tarrant , Dong Sung Lim , Xiaokang Zhu , Dawoon Jung , Rama K. Mishra
IPC分类号： C07D277/66 , C07D277/74 , C07D277/82 , A61K31/428
CPC分类号： C07D417/06 , C07D417/04 , C07D417/12 , C07D417/14
摘要： The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.
摘要翻译：本发明提供具有一般结构式（I）的化合物及其药学上可接受的衍生物，如本文中一般和本类和亚类所述，并且另外提供其药物组合物，以及用于治疗任何一种涉及纤维化和增殖的病症或疾病，其中抗纤维化或抗增殖活性是有益的。

3. 发明申请

US20150158853A1 CYTOCHROME P450 INHIBITORS AND USES THEREOF 审中-公开
标题翻译：细胞色素P450抑制剂及其用途
公开(公告)号：US20150158853A1
公开(公告)日：2015-06-11
申请号：US14493976
申请日：2014-09-23
申请人： Bijoy Panicker , Dong Sung Lim , Rama K. Mishra , Lambertus J.W.M. Oehlen , James G. Tarrant , Xiaokang Zhu , Dawoon Jung
发明人： Bijoy Panicker , Dong Sung Lim , Rama K. Mishra , Lambertus J.W.M. Oehlen , James G. Tarrant , Xiaokang Zhu , Dawoon Jung
IPC分类号： C07D417/06 , C07D417/14
CPC分类号： C07D417/06 , C07D417/04 , C07D417/12 , C07D417/14
摘要： The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.
摘要翻译：本发明提供具有一般结构式（I）的化合物及其药学上可接受的衍生物，如本文中一般和本类和亚类所述，并且另外提供其药物组合物，以及用于治疗任何一种涉及纤维化和增殖的病症或疾病，其中抗纤维化或抗增殖活性是有益的。

4. 发明申请

US20130102643A1 CYTOCHROME P450 INHIBITORS AND USES THEREOF 有权
公开(公告)号：US20130102643A1
公开(公告)日：2013-04-25
申请号：US13700730
申请日：2011-06-01
申请人： Bijoy Panicker , Lambertus J.W.M. Oehlen , James G. Tarrant , Dong Sung Lim , Xiaokang Zhu , Dawoon Jung , Rama K. Mishra
发明人： Bijoy Panicker , Lambertus J.W.M. Oehlen , James G. Tarrant , Dong Sung Lim , Xiaokang Zhu , Dawoon Jung , Rama K. Mishra
IPC分类号： C07D417/06
CPC分类号： C07D417/06 , C07D417/04 , C07D417/12 , C07D417/14
摘要： The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.

5. 发明申请

US20140018401A1 CYTOCHROME P450 INHIBITORS AND USES THEREOF 有权
标题翻译：细胞色素P450抑制剂及其用途
公开(公告)号：US20140018401A1
公开(公告)日：2014-01-16
申请号：US13935517
申请日：2013-07-04
申请人： Bijoy Panicker , Dong Sung Lim , Rama K. Mishra , Lambertus J.W.M. Oehlen , James G. Tarrant , Xiaokang Zhu , Dawoon Jung
发明人： Bijoy Panicker , Dong Sung Lim , Rama K. Mishra , Lambertus J.W.M. Oehlen , James G. Tarrant , Xiaokang Zhu , Dawoon Jung
IPC分类号： C07D417/12
CPC分类号： C07D417/06 , C07D417/04 , C07D417/12 , C07D417/14
摘要： The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.
摘要翻译：本发明提供具有一般结构式（I）的化合物及其药学上可接受的衍生物，如本文中一般和本类和亚类所述，并且另外提供其药物组合物，以及用于治疗任何一种涉及纤维化和增殖的病症或疾病，其中抗纤维化或抗增殖活性是有益的。

6. 发明授权

US09040555B2 Antifibrotic compounds and uses thereof 有权
标题翻译：抗纤维化合物及其用途
公开(公告)号：US09040555B2
公开(公告)日：2015-05-26
申请号：US14374210
申请日：2013-01-26
申请人： Bijoy Panicker , Rama K. Mishra , Dong Sung Lim , Lambertus J. W. M. Oehlen , Dawoon Jung
发明人： Bijoy Panicker , Rama K. Mishra , Dong Sung Lim , Lambertus J. W. M. Oehlen , Dawoon Jung
IPC分类号： C07D401/02 , C07D401/10 , C07D401/14 , A61K31/4353 , A61K31/437 , C07D471/04
CPC分类号： A61K31/4353 , A61K31/437 , A61K31/496 , A61K31/5377 , C07D401/02 , C07D401/14 , C07D471/04
摘要： The present invention provides compounds having the general structural formula (I), and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving abnormal or excessive fibrosis.
摘要翻译：本发明提供具有一般结构式（I）的化合物及其药学上可接受的衍生物，如本文中一般和本领域和亚类所述，并且另外提供其药物组合物及其用于治疗任何涉及异常或过度纤维化的病情或疾病数。

7. 发明申请

US20110098304A1 Small molecule inhibitors of PARP activity 审中-公开
标题翻译： PARP活性的小分子抑制剂
公开(公告)号：US20110098304A1
公开(公告)日：2011-04-28
申请号：US12592163
申请日：2009-11-19
申请人： Bijoy Panicker , Dawoon Jung , Xiaokang Zhu , David E. Smith , Dong Sung Lim
发明人： Bijoy Panicker , Dawoon Jung , Xiaokang Zhu , David E. Smith , Dong Sung Lim
IPC分类号： A61K31/502 , C07D237/32 , A61P25/16 , A61P9/10 , A61P25/28 , A61P9/12 , A61P3/10 , A61P13/12 , A61P1/16
CPC分类号： C07D237/32 , A61K31/502
摘要： Componds and pharmaceutical compositions are provided that inhibit the activity of poly ADP-ribose synthetase (PARP). Such componds are useful in the treatment of various diseases, conditions and injuries such as stroke, myocardial infarction, ischemia-perfusion injury in various organs, traumatic brain injury, atherosclerosis, inflammatory diseases and cancer.
摘要翻译：提供了抑制聚ADP-核糖合成酶（PARP）的活性的组合物和药物组合物。这样的化合物可用于治疗各种疾病，病症和损伤，例如中风，心肌梗死，各种器官中的缺血灌注损伤，创伤性脑损伤，动脉粥样硬化，炎性疾病和癌症。

8. 发明申请

US20080058312A1 Modulators of hepatocyte growth factor/c-Met activity 审中-公开
标题翻译：肝细胞生长因子/ c-Met活性调节剂
公开(公告)号：US20080058312A1
公开(公告)日：2008-03-06
申请号：US11651926
申请日：2007-01-10
申请人： David Zembower , Jasbir Singh , Rama Mishra , Dawoon Jung , Xiaokang Zhu
发明人： David Zembower , Jasbir Singh , Rama Mishra , Dawoon Jung , Xiaokang Zhu
IPC分类号： A61K31/517 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K31/55 , A61P19/02 , A61P35/00
CPC分类号： C07D239/95 , C07D239/48 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D405/12 , C07D409/12 , C07D413/04
摘要： This invention is directed to compounds and compositions that have biological properties useful for modulating HGF/SF activity. In certain embodiments, said compounds and compositions may be used in the treatment and prophylaxis of cancer or other dysproliferative diseases and inflammatory diseases such as rheumatoid arthritis.
摘要翻译：本发明涉及具有可用于调节HGF / SF活性的生物学特性的化合物和组合物。在某些实施方案中，所述化合物和组合物可用于治疗和预防癌症或其它增生性疾病和炎性疾病如类风湿性关节炎。

9. 发明申请

US20070213319A1 Modulators of hepatocyte growth factor/c-Met activity 审中-公开
标题翻译：肝细胞生长因子/ c-Met活性调节剂
公开(公告)号：US20070213319A1
公开(公告)日：2007-09-13
申请号：US11651927
申请日：2007-01-10
申请人： David Zembower , Jasbir Singh , Rama Mishra , Dawoon Jung , Xiaokang Zhu
发明人： David Zembower , Jasbir Singh , Rama Mishra , Dawoon Jung , Xiaokang Zhu
IPC分类号： A61K31/55 , A61K31/5377 , A61K31/517 , C07D413/02 , C07D405/02 , C07D403/02
CPC分类号： C07D239/95 , C07D239/48 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D405/12 , C07D409/12 , C07D413/04
摘要： This invention is directed to compounds and compositions that have biological properties useful for modulating HGF/SF activity. In certain embodiments, said compounds and compositions may be used in the treatment and prophylaxis of cancer or other dysproliferative diseases, as well as inflammatory diseases such as rheumatoid arthritis.
摘要翻译：本发明涉及具有可用于调节HGF / SF活性的生物学特性的化合物和组合物。在某些实施方案中，所述化合物和组合物可用于治疗和预防癌症或其它增生性疾病，以及炎性疾病如类风湿性关节炎。

10. 发明授权

US09292551B2 Storage device and stream filtering method thereof 有权
标题翻译：存储设备及其流过滤方法
公开(公告)号：US09292551B2
公开(公告)日：2016-03-22
申请号：US14021081
申请日：2013-09-09
申请人： Jeonguk Kang , Dawoon Jung , Chanik Park
发明人： Jeonguk Kang , Dawoon Jung , Chanik Park
IPC分类号： G06F17/30
CPC分类号： G06F17/30312 , G06F17/30516
摘要： A storage device may include a main storage part including memories; and a controller configured to control an overall operation of the main storage part. The controller includes a filter manager configured to store data format information and a filtering condition provided from a host; stream filters configured to search and project data stored in the memories in parallel in response to a control of the filter manager to produce searched and projected data; and a merge filter configured to merge the searched and projected data of the stream filters in response to the control of the filter manager.
摘要翻译：存储装置可以包括包括存储器的主存储部分; 以及控制器，被配置为控制主存储部的整体操作。控制器包括被配置为存储从主机提供的数据格式信息和滤波条件的滤波器管理器; 流滤波器，被配置为响应于过滤器管理器的控制并行地搜索和投影存储在存储器中的数据，以产生搜索和投影的数据; 以及合并过滤器，其被配置为响应于过滤器管理器的控制来合并流过滤器的搜索和投影数据。

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