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1. 发明授权

US06842484B2 Method and apparatus for random forced intra-refresh in digital image and video coding 有权
标题翻译：用于数字图像和视频编码中的随机强制内部刷新的方法和装置
公开(公告)号：US06842484B2
公开(公告)日：2005-01-11
申请号：US09902438
申请日：2001-07-10
申请人： Bhavan Gandhi , Kevin O'Connell , David Nicozisin
发明人： Bhavan Gandhi , Kevin O'Connell , David Nicozisin
IPC分类号： H04N7/26 , H04N7/50 , H04N7/12
CPC分类号： H04N19/423 , H04N19/107 , H04N19/17 , H04N19/61
摘要： A method and apparatus for reducing error propagation in digital video signals using random forced intra-refresh of macroblocks. One or more predetermined regions are defined for each digital video frame. Within each predetermined region, a number of macroblocks are selected according to a random permutation of the macroblocks within the region. The selected macroblocks are intra-coded, while the remaining macroblocks are coded according to a standard video compression protocol. This approach provides an efficient method for mitigating error propagation in a decoder. Interior regions may be smaller than exterior regions, providing higher quality for the interior regions, where sensitivity to errors is higher.
摘要翻译：一种使用宏块的随机强制内部刷新来减少数字视频信号中的误差传播的方法和装置。为每个数字视频帧定义一个或多个预定区域。在每个预定区域内，根据该区域内的宏块的随机排列选择多个宏块。所选择的宏块是帧内编码的，而剩余的宏块根据标准视频压缩协议进行编码。这种方法提供了一种用于减轻解码器中的错误传播的有效方法。内部区域可以小于外部区域，为内部区域提供更高的质量，其中误差的敏感性更高。

2. 发明授权

US06836514B2 Method for the detection and recovery of errors in the frame overhead of digital video decoding systems 有权
标题翻译：用于检测和恢复数字视频解码系统的帧开销中的错误的方法
公开(公告)号：US06836514B2
公开(公告)日：2004-12-28
申请号：US09901809
申请日：2001-07-10
申请人： Bhavan Gandhi , Kevin O'Connell , Faisal Ishtiaq , Raghavan Subramaniyan
发明人： Bhavan Gandhi , Kevin O'Connell , Faisal Ishtiaq , Raghavan Subramaniyan
IPC分类号： H04N718
CPC分类号： H04L1/20
摘要： The disclosed invention is a method to detect candidate errors within the picture start code, picture header, and picture timestamp. Upon detection, these errors may be confirmed and the impacts mitigated. An error within the timestamp bit field is adaptively detected by the use of a threshold comparison, and a mechanism for concealing the timestamp information leaves only a small timestamp anomaly. An error within the picture start code (PSC) is determined by adaptively analyzing the number of bits and the macro-block location of the next slice or GOB. If a PSC is suspected to have been overrun due to an error, this method allows for data beyond the first GOB or slice to be recovered in the frame. Depending on the extent of use of slices and GOBs, the method can recover a majority of the frame that otherwise would have been completely lost. A candidate error within the picture header is evaluated by utilizing the first slice or GOB of the frame and analyzing information from a previous frame to check whether the current frame's header information should be replaced with the previous frame's header information. Replacing the erred frame header can result in a majority of the data within the frame being recovered that would otherwise be discarded if the header was not replaced.
摘要翻译：所公开的发明是检测图像起始码，图像头部和图像时间戳内的候选误差的方法。经检测，可能会确认这些错误，并减轻影响。通过使用阈值比较来自适应地检测时间戳位字段内的错误，并且用于隐藏时间戳信息的机制仅留下小的时间戳异常。通过自适应地分析下一个切片或GOB的位数和宏块位置来确定图像起始码（PSC）内的错误。如果PSC被怀疑由于错误而被超载，则该方法允许超出第一个GOB或切片的数据在帧中被恢复。根据切片和GOB的使用范围，该方法可以恢复否则将完全丢失的大部分帧。通过利用帧的第一片或GOB并分析来自前一帧的信息来评估图片头中的候选错误，以检查当前帧的标题信息是否应该被前一帧的标题信息替换。更换错误的帧头可能会导致正在恢复的帧内的大部分数据，否则如果未更换标题，则将被丢弃。

3. 发明申请

US20140056942A1 LIQUID STABLE VIRUS VACCINES 有权
标题翻译：液体稳定的病毒疫苗
公开(公告)号：US20140056942A1
公开(公告)日：2014-02-27
申请号：US13967847
申请日：2013-08-15
申请人： Zhisong Qiao , Kevin O'Connell
发明人： Zhisong Qiao , Kevin O'Connell
IPC分类号： A61K47/42 , A61K39/155 , A61K39/175 , A61K47/10 , A61K47/18 , A61K47/20 , A61K47/22 , A61K47/26 , A61K39/23 , A61K39/235
CPC分类号： A61K39/235 , A61K9/08 , A61K39/0225 , A61K39/12 , A61K39/145 , A61K39/155 , A61K39/175 , A61K39/23 , A61K47/10 , A61K47/183 , A61K47/20 , A61K47/22 , A61K47/26 , A61K47/42 , A61K2039/521 , A61K2039/5252 , A61K2039/5254 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N2710/10034 , C12N2750/14034 , C12N2750/14322 , C12N2760/18034 , C12N2760/18434 , C12N2760/18634
摘要： The present invention discloses liquid stable vaccines that comprise a live attenuated virus, 10-30% sugar additive, and an amino acid. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines.
摘要翻译：本发明公开了包含活减毒病毒，10-30％糖添加剂和氨基酸的液体稳定疫苗。本发明还公开了通过这种疫苗的施用来制备这种疫苗和保护动物的方法。

4. 发明申请

US20180154090A1 Sprayer Technology 审中-公开
公开(公告)号：US20180154090A1
公开(公告)日：2018-06-07
申请号：US15530096
申请日：2016-12-01
申请人： Mark L. Anderson , John Harmon , Brian Husby , Kevin O'Connell
发明人： Mark L. Anderson , John Harmon , Brian Husby , Kevin O'Connell
IPC分类号： A61M11/00 , A61M15/08 , A61K39/145 , C12N7/00
CPC分类号： A61M11/007 , A61K39/12 , A61K2039/543 , A61K2039/552 , A61M15/0025 , A61M15/08 , A61M2250/00 , C12N2760/16034 , C12N2760/16134
摘要： A spray apparatus adapted to be connected to a fluid supply such as a syringe to spray a predetermined pattern of spray fluid to a target area such as the tissues of an animal or human. The sprayer is particularly well suited to delivering a predetermined dose of a medicament, vaccine or the like to the nasal or other cavity of an animal or human patient. The sprayer includes a base member and a cap member which is connected to the base member. The base member is connectible to the fluid supply. Spray is discharged from the distal or outward end of the cap member. The base member has a central, longitudinal lumen having a predetermined configuration. Fluid traverses the lumen and is discharged through a central aperture of the cap, which also has a predetermined configuration. The cap central lumen and spray discharge aperture are aligned with the base lumen. Methods of use, including animal vaccination, and manufacture are also disclosed.

5. 发明授权

US08980283B2 C. perfringens alpha toxoid vaccine 有权
标题翻译：产气荚膜梭菌α类毒素疫苗
公开(公告)号：US08980283B2
公开(公告)日：2015-03-17
申请号：US11405198
申请日：2006-04-17
申请人： Huchappa Jayappa , Kevin O'Connell
发明人： Huchappa Jayappa , Kevin O'Connell
IPC分类号： A61K39/08 , A61K39/02 , A61K39/00 , A61K39/38 , A61K39/40 , A61K45/00 , A61K47/00
CPC分类号： A61K39/08 , A61K39/0258 , A61K2039/55 , A61K2039/552 , A61K2039/70
摘要： The present invention describes vaccines that comprise C. perfringens Type alpha toxoids, antigenic fragments thereof, inactivated antigenic fragments of C. perfringens Type alpha toxins, or any combination thereof. The present invention further describes methods of using with these vaccines to protect animals against clostridial diseases. The present invention also describes methods of making these vaccines.
摘要翻译：本发明描述了包含产气荚膜梭菌α型类毒素，其抗原性片段，产气荚膜梭菌型α毒素的灭活抗原片段或其任何组合的疫苗。本发明还描述了与这些疫苗一起使用以保护动物免受梭菌病的方法。本发明还描述了制备这些疫苗的方法。

6. 发明申请

US20140017318A1 METHOD TO PRODUCE A MEDICINAL PRODUCT COMPRISING A BIOLOGICALLY ACTIVE PROTEIN AND THE RESULTING PRODUCT 审中-公开
标题翻译：生产包含生物活性蛋白质和结果产品的药物产品的方法
公开(公告)号：US20140017318A1
公开(公告)日：2014-01-16
申请号：US13936500
申请日：2013-07-08
申请人： Kevin O'Connell , Sandhya Buchanan
发明人： Kevin O'Connell , Sandhya Buchanan
IPC分类号： A61K47/36 , A61K38/00
CPC分类号： A61K9/19 , A61K38/00 , A61K39/155 , A61K39/175 , A61K39/235 , A61K47/26 , A61K47/36 , A61K2039/5254 , C12N2710/10334 , C12N2760/18434 , C12N2760/18711
摘要： The present invention pertains to a method for producing a medicinal product comprising a biologically active protein comprising the steps of providing an aqueous composition comprising a solvent, the biologically active protein and between 20% w/w and 60% w/w of a non-polymeric sugar, freezing the composition, thereby forming at least one frozen body comprising the solvent in frozen form, putting the frozen body in a drying apparatus while being carried by a support, the support comprising one or more restraining elements that define one or more boundaries of the support, wherein at most 30% of the surface of the body is contiguous with the one or more restraining elements, reducing the pressure in the drying apparatus below atmospheric pressure, providing heat to the body in order to sublimate the frozen solvent of the body and obtain a dried body. The invention also pertains to a product obtainable by this method.
摘要翻译：本发明涉及一种生产包含生物活性蛋白质的药用产品的方法，包括以下步骤：提供包含溶剂，生物活性蛋白质和20％w / w至60％w / w的非水性组合物的水性组合物，聚合糖，冷冻组合物，从而形成至少一个包含冷冻形式的溶剂的冷冻体，将冷冻的身体放在干燥装置中同时被支撑物携带，所述支撑体包括限定一个或多个边界的一个或多个约束元件的载体，其中至少30％的身体表面与一个或多个约束元件邻接，将干燥装置中的压力降低到大气压力以下，为身体提供热量，以使冷冻溶剂升华身体并获得干燥的身体。本发明还涉及通过该方法可获得的产品。

7. 发明申请

US20110305114A1 SEISMIC SURVEY COMMUNICATION SYSTEMS AND METHODS 审中-公开
标题翻译：地震调查通信系统与方法
公开(公告)号：US20110305114A1
公开(公告)日：2011-12-15
申请号：US13156723
申请日：2011-06-09
申请人： Daniel Golparian , Guillaume Tamboise , Sharath Babu Musunoori , Kevin O'Connell
发明人： Daniel Golparian , Guillaume Tamboise , Sharath Babu Musunoori , Kevin O'Connell
IPC分类号： G01V1/22
CPC分类号： G01V1/003
摘要： An embodiment of the invention may extend the range of wireless communications in a seismic acquisition survey. The embodiment may leverage the infrastructure of a hard-wired communications backbone by appending wireless cells to the hard-wired communications. This may allow, for example, a recording truck to control remotely located seismic sources via wireless communications in the spread. Another embodiment includes a communication system for servicing field equipment. The embodiment provides for a fully or semi automated process for communicating equipment failures between survey personnel (e.g., recording truck operators and line observers). The embodiment establishes an end-to-end channel between, for example, the recording truck and field crew members. Other embodiments are disclosed herein.
摘要翻译：本发明的实施例可以扩展地震采集调查中无线通信的范围。该实施例可以通过将无线小区附加到硬连线通信来利用硬连线通信骨干网的基础设施。这可以允许例如记录卡车通过传播中的无线通信来控制远程定位的地震源。另一个实施例包括用于维护现场设备的通信系统。该实施例提供了用于在测量人员（例如记录卡车操作员和线路观察者）之间通信设备故障的完全或半自动化过程。该实施例在例如记录卡车和现场机组成员之间建立端到端通道。本文公开了其它实施例。

8. 发明授权

US11141545B2 Sprayer technology 有权
公开(公告)号：US11141545B2
公开(公告)日：2021-10-12
申请号：US15530096
申请日：2016-12-01
申请人： Mark L. Anderson , John Harmon , Brian Husby , Kevin O'Connell
发明人： Mark L. Anderson , John Harmon , Brian Husby , Kevin O'Connell
IPC分类号： A61M11/00 , A61M15/08 , A61K39/00 , A61K39/12 , A61M15/00
摘要： A spray apparatus adapted to be connected to a fluid supply such as a syringe to spray a predetermined pattern of spray fluid to a target area such as the tissues of an animal or human. The sprayer delivers a predetermined dose of a medicament, vaccine or the like to the nasal or other cavity of an animal or human patient. The sprayer includes a base member and a cap member which is connected to the base member. The base member is connectible to the fluid supply. Spray is discharged from the distal or outward end of the cap member. The base member has a central, longitudinal lumen having a predetermined configuration. Fluid traverses the lumen and is discharged through a central aperture of the cap, which also has a predetermined configuration. The cap central lumen and spray discharge aperture are aligned with the base lumen.

9. 发明申请

US20140271709A1 BOVINE VIRUS VACCINES THAT ARE LIQUID STABLE 有权
标题翻译：牛肝病毒液体液体稳定
公开(公告)号：US20140271709A1
公开(公告)日：2014-09-18
申请号：US14202454
申请日：2014-03-10
申请人： Brad Eddy , Zhisong QIAO , Kevin O'Connell
发明人： Brad Eddy , Zhisong QIAO , Kevin O'Connell
IPC分类号： A61K39/12 , A61K47/18 , A61K39/215 , A61K47/26 , A61K39/245 , A61K39/155
CPC分类号： A61K39/39 , A61K39/02 , A61K39/0208 , A61K39/102 , A61K39/12 , A61K39/155 , A61K39/215 , A61K39/245 , A61K39/265 , A61K47/183 , A61K47/26 , A61K2039/5254 , A61K2039/552 , A61K2039/55583 , A61K2039/70 , C12N7/00 , C12N2710/16734 , C12N2760/12234 , C12N2760/18034 , C12N2760/18634 , C12N2770/20034 , C12N2770/24333 , C12N2770/24334
摘要： The present invention discloses liquid stable bovine vaccines that comprise a live attenuated virus, and a sugar alcohol. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines.
摘要翻译：本发明公开了包含活减毒病毒和糖醇的液体稳定的牛疫苗。本发明还公开了通过这种疫苗的施用来制备这种疫苗和保护动物的方法。

10. 发明申请

US20120069706A1 Land Seismic Cable and Method 审中-公开
标题翻译：陆地地震电缆和方法
公开(公告)号：US20120069706A1
公开(公告)日：2012-03-22
申请号：US12886319
申请日：2010-09-20
申请人： Nicolas Goujon , Emmanuel Coste , Qinglin Liu , Kevin O'Connell , Jostein Fonneland , Kazuya Yoshida , Hitoshi Tashiro
发明人： Nicolas Goujon , Emmanuel Coste , Qinglin Liu , Kevin O'Connell , Jostein Fonneland , Kazuya Yoshida , Hitoshi Tashiro
IPC分类号： G01V1/18 , F16L1/028
CPC分类号： G01V1/201
摘要： A seismic cable for use in land applications is described. The cable includes seismic sensors for measuring seismic signals reflected from subterranean or subsea formations. The cable may be deployed in trenches dug in the survey region to provide adequate sensor coupling to ground. Sensor units may be inline with the cable and may further be disposed in slim casings, thus facilitating handling and deployment.
摘要翻译：描述了用于陆地应用的地震电缆。电缆包括用于测量地下或海底地层反射的地震信号的地震传感器。电缆可以部署在调查区域挖出的沟槽中，以提供足够的传感器耦合到地面。传感器单元可以与电缆线对齐，并且可以进一步放置在细长的外壳中，从而便于处理和展开。

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