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1. 发明授权

US09943622B2 Minimizing biological lipid deposits on contact lenses 有权
公开(公告)号：US09943622B2
公开(公告)日：2018-04-17
申请号：US14427928
申请日：2013-09-24
申请人： Bausch & Lomb Incorporated
发明人： X. Michael Liu , Joseph A. Chinn , George L. Grobe, III , E. Peter Maziarz
IPC分类号： A61L12/14 , C11D1/62 , C11D3/00 , C11D3/48 , A61K9/00
CPC分类号： A61L12/143 , A61K9/0051 , A61L12/14 , A61L12/145 , C11D1/62 , C11D3/0078 , C11D3/48
摘要： Method for minimizing the sorption of tear lipids on frequent replacement, or extended-wear, contact lenses, the method comprising (a) contacting the contact lens selected from the group consisting of senofilcon A, lotrafilcon A, lotrafilcon B, and comfilcon A B with a lens care solution for a period of at least three hours to minimize the accumulation of tear lipids on the contact lens. The lens care solution comprises 0.5 ppm to 10 ppm α-[4-tris(2-hydroxyethyl)-ammonium chloride-2-butenyl]poly[1-dimethyl ammonium chloride-2-butenyl]-ω-tris(2-hydroxyethyl) ammonium chloride; citrate, citric acid or a mixture thereof; and 0.005 wt. % to 0.05 wt. % hyaluronic acid. The method also includes (b) inserting the soaked contact lens into one's eye, and (c) repeating steps (a) and (b).

2. 发明申请

US20160022860A1 MINIMIZING BIOLOGICAL LIPID DEPOSITS ON CONTACT LENSES 有权
标题翻译：最小化接触眼镜上的生物脂质沉积
公开(公告)号：US20160022860A1
公开(公告)日：2016-01-28
申请号：US14427928
申请日：2013-09-24
申请人： BAUSCH & LOMB INCORPORATED
发明人： X. Michael Liu , Joseph A. Chinn , George L. Grobe , E. Peter Maziarz
IPC分类号： A61L12/14
CPC分类号： A61L12/143 , A61K9/0051 , A61L12/14 , A61L12/145 , C11D1/62 , C11D3/0078 , C11D3/48
摘要： Method for minimizing the sorption of tear lipids on frequent replacement, or extended-wear, contact lenses, the method comprising (a) contacting the contact lens selected from the group consisting of senofilcon A, lotrafilcon A, lotrafilcon B, and comfilcon A B with a lens care solution for a period of at least three hours to minimize the accumulation of tear lipids on the contact lens. The lens care solution comprises 0.5 ppm to 10 ppm α-[4-tris(2-hydroxyethyl)-ammonium chloride-2-butenyl]poly[1-dimethyl ammonium chloride-2-butenyl]-ω-tris(2-hydroxyethyl) ammonium chloride; citrate, citric acid or a mixture thereof; and 0.005 wt. % to 0.05 wt. % hyaluronic acid. The method also includes (b) inserting the soaked contact lens into one's eye, and (c) repeating steps (a) and (b).
摘要翻译：用于最大限度地减少频繁更换或延长磨损的隐形眼镜对泪液的吸附的方法，所述方法包括（a）将选自由以下组成的组的接触镜片接触：塞芬芬康A，lotrafilcon A，lotrafilcon B和comfilcon AB与晶状体护理溶液至少3小时，以尽量减少泪液在隐形眼镜上的积累。镜片护理液包含0.5ppm至10ppm的α-[4-三（2-羟乙基） - 氯化铵-2-丁烯基]聚[1-二甲基氯化铵-2-丁烯基]-ω-三（2-羟乙基）氯化铵; 柠檬酸盐，柠檬酸或其混合物; 和0.005wt。％〜0.05重量％％透明质酸。该方法还包括（b）将浸泡的隐形眼镜插入眼中，和（c）重复步骤（a）和（b）。

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