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1. 发明授权

US08456629B2 Apparatus and method for multiple-pulse impulsive stimulated raman spectroscopy 有权
标题翻译：多脉冲脉冲刺激拉曼光谱仪的装置和方法
公开(公告)号：US08456629B2
公开(公告)日：2013-06-04
申请号：US12945030
申请日：2010-11-12
申请人： Bahram Jalali , Keisuke Goda , Akira Sato , Kenji Taira
发明人： Bahram Jalali , Keisuke Goda , Akira Sato , Kenji Taira
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01N2021/655
摘要： Spectroscopic measurements are described based on light-molecule interaction in response to a resonant rate optical pulse train so that a Raman spectrum is reflected containing at least two types of vibrational mode information (e.g., vibrational frequency, and vibrational phase relaxation) on the molecules comprising the object. A pump optical pulse train generation means is configured for generating an optical pulse train having an arbitrary repetition rate which is directed through irradiation means to the sample object. Light from the sample object is collected and vibrational coherence is detected for the sample object. The sample is tested across a plurality of different repetition frequencies. The detected information can be compared with data from other known samples from within a database when analyzing the information collected.
摘要翻译：基于响应于谐振速率光脉冲序列的光分子相互作用来描述光谱测量，使得反射的拉曼光谱包含至少两种类型的振动模式信息（例如振动频率和振动相松弛），包括物体。泵浦光脉冲串产生装置被配置为产生具有任意重复频率的光脉冲序列，其通过照射装置被引导到样本物体。收集来自样品物体的光并检测样品物体的振动相干性。在多个不同的重复频率上测试样本。当分析收集的信息时，检测到的信息可以与数据库内其他已知样本的数据进行比较。

2. 发明申请

US20110122407A1 APPARATUS AND METHOD FOR MULTIPLE-PULSE IMPULSIVE STIMULATED RAMAN SPECTROSCOPY 有权
标题翻译：多脉冲刺激拉曼光谱法的装置与方法
公开(公告)号：US20110122407A1
公开(公告)日：2011-05-26
申请号：US12945030
申请日：2010-11-12
申请人： Bahram Jalali , Keisuke Goda , Akira Sato , Kenji Taira
发明人： Bahram Jalali , Keisuke Goda , Akira Sato , Kenji Taira
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01N2021/655
摘要： Spectroscopic measurements are described based on light-molecule interaction in response to a resonant rate optical pulse train so that a Raman spectrum is reflected containing at least two types of vibrational mode information (e.g., vibrational frequency, and vibrational phase relaxation) on the molecules comprising the object. A pump optical pulse train generation means is configured for generating an optical pulse train having an arbitrary repetition rate which is directed through irradiation means to the sample object. Light from the sample object is collected and vibrational coherence is detected for the sample object. The sample is tested across a plurality of different repetition frequencies. The detected information can be compared with data from other known samples from within a database when analyzing the information collected.
摘要翻译：基于响应于谐振速率光脉冲序列的光分子相互作用来描述光谱测量，使得反射的拉曼光谱包含至少两种类型的振动模式信息（例如振动频率和振动相松弛），包括物体。泵浦光脉冲串产生装置被配置为产生具有任意重复频率的光脉冲序列，其通过照射装置被引导到样本物体。收集来自样品物体的光并检测样品物体的振动相干性。在多个不同的重复频率上测试样本。当分析收集的信息时，检测到的信息可以与数据库内其他已知样本的数据进行比较。

3. 发明授权

US08440952B2 Methods for optical amplified imaging using a two-dimensional spectral brush 有权
公开(公告)号：US08440952B2
公开(公告)日：2013-05-14
申请号：US12621496
申请日：2009-11-18
申请人： Bahram Jalali , Keisuke Goda , Kevin Kin-Man Tsia
发明人： Bahram Jalali , Keisuke Goda , Kevin Kin-Man Tsia
IPC分类号： H01L27/00 , H01L31/00
CPC分类号： G02B21/361 , A61B1/00009 , A61B1/00193 , A61B1/0638 , A61B5/0062 , A61B5/0066 , A61B5/0075 , A61B5/0086 , A61B5/7257 , G01B9/02004 , G01B9/02014 , G01B9/02028 , G01B9/02044 , G01B9/02091 , G01B11/2441 , G01B2290/20 , G01B2290/65 , G06K9/2036 , G06K2209/05 , H04N9/045
摘要： An apparatus and method for ultrafast real-time optical imaging that can be used for imaging dynamic events such as microfluidics or laser surgery is provided. The apparatus and methods encode spatial information from a sample into a back reflection of a two-dimensional spectral brush that is generated with a two-dimensional disperser and a light source that is mapped in to the time domain with a temporal disperser. The temporal waveform is preferably captured by an optical detector, converted to an electrical signal that is digitized and processed to provide two dimensional and three dimensional images. The produced signals can be optically or electronically amplified. Detection may be improved with correlation matching against a database in the time domain or the spatial domain. Embodiments for endoscopy, microscopy and simultaneous imaging and laser ablation with a single fiber are illustrated.

4. 发明授权

US08376218B2 Apparatus and method for dispersive fourier-transform imaging 有权
标题翻译：色散傅里叶变换成像装置及方法
公开(公告)号：US08376218B2
公开(公告)日：2013-02-19
申请号：US12985539
申请日：2011-01-06
申请人： Bahram Jalali , Keisuke Goda , Kevin Kin-Man Tsia
发明人： Bahram Jalali , Keisuke Goda , Kevin Kin-Man Tsia
IPC分类号： G06F17/00
CPC分类号： G06K7/1439 , G06K7/10712 , G06K7/10831 , G06K7/14
摘要： A barcode reading apparatus and method in which the spectrum of a probe light is first Fourier-transformed into space, directed upon a barcode, and then Fourier-transformed converting the spectrally encoded barcode pattern to a time domain waveform. In one implementation, the Fourier transformation from the spectrum domain into a spatial domain is performed by a dispersive element, while the Fourier transformation from the spectrally encoded barcode pattern to a time domain waveform is performed by group-velocity dispersion (GVD). The temporally encoded barcode pattern is detected by a photodetector, digitized by a digitizer, and analyzed by a digital signal processor. The invention is applicable to a number of fields which involve the reading of one- and two-dimensional barcodes, displacement sensing, surface measurements, measurement of width and gap, flow cytometry, reading of optical media, presence or absence detection, and other related fields.
摘要翻译：一种条形码读取装置和方法，其中探针光的光谱首先被傅里叶变换为空间，指向条形码，然后经频谱转换成频谱编码的条形码图案到时域波形。在一个实现中，通过色散元素执行从频域到空间域的傅立叶变换，而通过组速度色散（GVD）执行从频谱编码的条形码图案到时域波形的傅里叶变换。时间编码的条形码图案由光电检测器检测，由数字化仪数字化，并由数字信号处理器分析。本发明适用于涉及读取一维和二维条形码，位移检测，表面测量，宽度和间隙测量，流式细胞术，光学介质读数，有无检测等相关领域的多个领域领域。

5. 发明申请

US20110168776A1 APPARATUS AND METHOD FOR DISPERSIVE FOURIER-TRANSFORM IMAGING 有权
标题翻译：用于分散式FOURIER-TRANSFORM成像的装置和方法
公开(公告)号：US20110168776A1
公开(公告)日：2011-07-14
申请号：US12985539
申请日：2011-01-06
申请人： Bahram Jalali , Keisuke Goda , Kevin Kin-Man Tsia
发明人： Bahram Jalali , Keisuke Goda , Kevin Kin-Man Tsia
IPC分类号： G06K7/14 , G06F17/00 , G06Q90/00 , G01B11/14
CPC分类号： G06K7/1439 , G06K7/10712 , G06K7/10831 , G06K7/14
摘要： A barcode reading apparatus and method in which the spectrum of a probe light is first Fourier-transformed into space, directed upon a barcode, and then Fourier-transformed converting the spectrally encoded barcode pattern to a time domain waveform. In one implementation, the Fourier transformation from the spectrum domain into a spatial domain is performed by a dispersive element, while the Fourier transformation from the spectrally encoded barcode pattern to a time domain waveform is performed by group-velocity dispersion (GVD). The temporally encoded barcode pattern is detected by a photodetector, digitized by a digitizer, and analyzed by a digital signal processor. The invention is applicable to a number of fields which involve the reading of one- and two-dimensional barcodes, displacement sensing, surface measurements, measurement of width and gap, flow cytometry, reading of optical media, presense or absence detection, and other related fields.
摘要翻译：一种条形码读取装置和方法，其中探针光的光谱首先被傅里叶变换为空间，指向条形码，然后经频谱转换成频谱编码的条形码图案到时域波形。在一个实现中，通过色散元素执行从频域到空间域的傅立叶变换，而通过组速度色散（GVD）执行从频谱编码的条形码图案到时域波形的傅里叶变换。时间编码的条形码图案由光电检测器检测，由数字化仪数字化，并由数字信号处理器分析。本发明可应用于涉及读取一维和二维条形码，位移检测，表面测量，宽度和间隙测量，流式细胞术，光学介质读数，预存或不存在检测等多个领域领域。

6. 发明申请

US20100141829A1 APPARATUS AND METHOD FOR OPTICALLY AMPLIFIED IMAGING 有权
标题翻译：用于光放大成像的装置和方法
公开(公告)号：US20100141829A1
公开(公告)日：2010-06-10
申请号：US12621496
申请日：2009-11-18
申请人： Bahram Jalali , Keisuke Goda , Kevin Kin-Man Tsia
发明人： Bahram Jalali , Keisuke Goda , Kevin Kin-Man Tsia
IPC分类号： H04N5/225 , G06K9/36
CPC分类号： G02B21/361 , A61B1/00009 , A61B1/00193 , A61B1/0638 , A61B5/0062 , A61B5/0066 , A61B5/0075 , A61B5/0086 , A61B5/7257 , G01B9/02004 , G01B9/02014 , G01B9/02028 , G01B9/02044 , G01B9/02091 , G01B11/2441 , G01B2290/20 , G01B2290/65 , G06K9/2036 , G06K2209/05 , H04N9/045
摘要： An apparatus and method for ultrafast real-time optical imaging that can be used for imaging dynamic events such as microfluidics or laser surgery is provided. The apparatus and methods encode spatial information from a sample into a back reflection of a two-dimensional spectral brush that is generated with a two-dimensional disperser and a light source that is mapped in to the time domain with a temporal disperser. The temporal waveform is preferably captured by an optical detector, converted to an electrical signal that is digitized and processed to provide two dimensional and three dimensional images. The produced signals can be optically or electronically amplified. Detection may be improved with correlation matching against a database in the time domain or the spatial domain. Embodiments for endoscopy, microscopy and simultaneous imaging and laser ablation with a single fiber are illustrated.
摘要翻译：提供了一种用于超快速实时光学成像的装置和方法，可用于成像诸如微流体或激光手术的动态事件成像。该装置和方法将来自样本的空间信息编码成二维光谱刷的背反射，其由二维分散器和用时间分散器映射到时域的光源产生。时间波形优选地由光学检测器捕获，转换成被数字化和处理以提供二维和三维图像的电信号。产生的信号可以是光学或电子放大的。可以通过与时域或空间域中的数据库的相关匹配来改进检测。示出了用于内窥镜检查，显微镜和同时成像以及使用单纤维的激光烧蚀的实施例。

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