专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20150368663A1 METHOD FOR ISOLATION OF TRANSCRIPTION TERMINATION SEQUENCES 审中-公开
标题翻译：用于分离转录终止序列的方法
公开(公告)号：US20150368663A1
公开(公告)日：2015-12-24
申请号：US14821872
申请日：2015-08-10
申请人： BASF Plant Science GmbH
发明人： Hee-Sook Song , Michael Kock , Jeffrey A. Brown , Linda Patricia Loyall , Liqun Xing , Hongmei Jia , John McMillan , Lesley Ireland
IPC分类号： C12N15/82
CPC分类号： C12N15/8261 , C12N15/1051 , C12N15/82 , C12N15/8216
摘要： The invention relates to efficient, high-throughput methods, systems, and DNA constructs for identification and isolation of transcription termination sequences. The invention relates further to specific terminator sequences identified by said methods isolated from rice.
摘要翻译：本发明涉及用于鉴定和分离转录终止序列的有效的高通量方法，系统和DNA构建体。本发明进一步涉及通过从水稻中分离的所述方法鉴定的特异性终止子序列。

2. 发明申请

US20130236954A1 Method for Isolation of Transcription Termination Sequences 有权
标题翻译：转录终止序列的分离方法
公开(公告)号：US20130236954A1
公开(公告)日：2013-09-12
申请号：US13894840
申请日：2013-05-15
申请人： BASF PLANT SCIENCE GMBH
发明人： Hee-Sook Song , Michael Kock , Jeffrey A. Brown , Linda Patricia Loyall , Liqun Xing , Hongmei Jia , John McMillan , Lesley Ireland
IPC分类号： C12N15/82
CPC分类号： C12N15/8261 , C12N15/1051 , C12N15/82 , C12N15/8216
摘要： The invention relates to efficient, high-throughput methods, systems, and DNA constructs for identification and isolation of transcription termination sequences. The invention relates further to specific terminator sequences identified by said methods isolated from rice.
摘要翻译：本发明涉及用于鉴定和分离转录终止序列的有效的高通量方法，系统和DNA构建体。本发明进一步涉及通过从水稻中分离的所述方法鉴定的特异性终止子序列。

3. 发明授权

US10676752B2 Methods controlling gene expression 有权
公开(公告)号：US10676752B2
公开(公告)日：2020-06-09
申请号：US14737789
申请日：2015-06-12
申请人： BASF Plant Science GmbH
发明人： Peifeng Ren , Hee-Sook Song , John McMillan
IPC分类号： C12N15/82 , C12N15/79
摘要： The present invention is in the field of genetics, especially plant genetics, and provides agents capable of controlling gene expression. The present invention specifically provides sequences of naturally occurring, tissue-specifically expressed microRNAs. The invention further provides for transgenic expression constructs comprising sequences encoding such microRNAs. By incorporation of the microRNA encoding sequence the expression from the expression construct is specifically silenced in the tissue where the naturally occurring microRNA is naturally expressed. Thereby the expression profile resulting from the promoter is modulated and leakiness is reduced. The invention further provides for a method for modulating transgenic expression by incorporating sequences encoding the microRNAs into transgenic expression constructs. The compositions and methods of the invention can be used to enhance performance of agricultural relevant crops and for therapy, prophylaxis, research and diagnostics in diseases and disorders, which afflict mammalian species.

4. 发明申请

US20160152994A1 METHODS CONTROLLING GENE EXPRESSION 审中-公开
标题翻译：控制基因表达的方法
公开(公告)号：US20160152994A1
公开(公告)日：2016-06-02
申请号：US14737789
申请日：2015-06-12
申请人： BASF Plant Science GmbH
发明人： PEIFENG REN , Hee-Sook Song , John McMillan
IPC分类号： C12N15/82
摘要： The present invention is in the field of genetics, especially plant genetics, and provides agents capable of controlling gene expression. The present invention specifically provides sequences of naturally occurring, tissue-specifically expressed microRNAs. The invention further provides for transgenic expression constructs comprising sequences encoding such microRNAs. By incorporation of the microRNA encoding sequence the expression from the expression construct is specifically silenced in the tissue where the naturally occurring microRNA is naturally expressed. Thereby the expression profile resulting from the promoter is modulated and leakiness is reduced. The invention further provides for a method for modulating transgenic expression by incorporating sequences encoding the microRNAs into transgenic expression constructs. The compositions and methods of the invention can be used to enhance performance of agricultural relevant crops and for therapy, prophylaxis, research and diagnostics in diseases and disorders, which afflict mammalian species.
摘要翻译：本发明涉及遗传学，特别是植物遗传学领域，并提供能够控制基因表达的试剂。本发明具体提供了天然存在的组织特异性表达的微小RNA的序列。本发明还提供包含编码这种微小RNA的序列的转基因表达构建体。通过并入microRNA编码序列，表达构建体的表达在天然存在的微RNA天然表达的组织中被特异性沉默。因此，由启动子产生的表达谱被调节并且泄漏降低。本发明进一步提供了通过将编码微小RNA的序列并入转基因表达构建体来调节转基因表达的方法。本发明的组合物和方法可用于增强农业相关作物的性能以及影响哺乳动物物种的疾病和病症的治疗，预防，研究和诊断。

5. 发明授权

US09133466B2 Method for isolation of transcription termination sequences 有权
标题翻译：分离转录终止序列的方法
公开(公告)号：US09133466B2
公开(公告)日：2015-09-15
申请号：US13894840
申请日：2013-05-15
申请人： BASF Plant Science GmbH
发明人： Hee-Sook Song , Michael Kock , Jeffrey A. Brown , Linda Patricia Loyall , Liqun Xing , Hongmei Jia , John McMillan , Lesley Ireland
IPC分类号： C12N15/82 , C07H21/04 , C12N15/10
CPC分类号： C12N15/8261 , C12N15/1051 , C12N15/82 , C12N15/8216
摘要： The invention relates to efficient, high-throughput methods, systems, and DNA constructs for identification and isolation of transcription termination sequences. The invention relates further to specific terminator sequences identified by said methods isolated from rice.
摘要翻译：本发明涉及用于鉴定和分离转录终止序列的有效的高通量方法，系统和DNA构建体。本发明进一步涉及通过从水稻中分离的所述方法鉴定的特异性终止子序列。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式