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1. 发明授权

US07282520B2 External preparation 有权
标题翻译：外部准备
公开(公告)号：US07282520B2
公开(公告)日：2007-10-16
申请号：US10489910
申请日：2002-09-13
申请人： Atsushi Yokomaku , Taketoshi Ito , Megumi Aono , Shinichi Watanabe , Yuichi Nishida
发明人： Atsushi Yokomaku , Taketoshi Ito , Megumi Aono , Shinichi Watanabe , Yuichi Nishida
IPC分类号： A61K31/235
CPC分类号： A61Q19/00 , A61K8/368 , A61K8/37 , A61K8/602 , A61K8/73 , A61Q1/10 , A61Q5/00 , A61Q5/02 , A61Q5/06 , A61Q7/00 , Y10S514/844 , Y10S514/881
摘要： An external preparation characterized by comprising, as selected from gallic acid derivatives of the following formula (I), wherein R1 represents a hydrogen atom, an alkali metal, an alkaline earth metal, an ammonium salt, or an alkyl or alkenyl group having from 1 to 18 carbon atoms and R2, R3, and R4 independently represent a hydrogen atom, an hydroxyl group, an alkoxy group having from 1 to 18 carbon atoms, a polyoxyethylene group, a polyoxypropylene group, or a residue of a monosaccharide, a disaccharide, or an oligosaccharide; 90 wt % or over of one or more gallic acid derivatives (A) wherein two of R2, R3, and R4 in the formula (I) independently represent a residue of a monosaccharide, disaccharide, or oligosaccharide and from 0.001 wt % to less than 10 wt % of one or more gallic acid derivatives (B) wherein one of R2, R3, and R4 represents a residue of a monosaccharide, disaccharide, or oligosaccharide, each based on the total content of the gallic acid derivatives.
摘要翻译：一种外用制剂，其特征在于，选自下式（I）的没食子酸衍生物，其中R 1表示氢原子，碱金属，碱土金属，铵盐或具有1至18个碳原子的烷基或烯基，R 2，R 3和R 4独立地表示氢原子，羟基，具有1至18个碳原子的烷氧基，聚氧乙烯基，聚氧丙烯基或单糖，二糖或寡糖的残基; 一种或多种没食子酸衍生物（A）的90重量％以上，其中R 2，R 3，R 4和R 4中的两个在式（I）独立地表示单糖，二糖或寡糖的残基，0.001重量％〜小于10重量％的一种或多种没食子酸衍生物（B），其中R 2， R 3，R 4表示单糖，二糖或寡糖的残基，各自以没食子酸衍生物的总含量为基准。

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