专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US6114693A Mass spectrometer and mass spectrometry method for analyzing compounds contained in a solution 有权
标题翻译：用于分析溶液中所含化合物的质谱仪和质谱法
公开(公告)号：US6114693A
公开(公告)日：2000-09-05
申请号：US299638
申请日：1999-04-27
申请人： Atsumu Hirabayashi , Yukiko Hirabayashi , Minoru Sakairi , Yasuaki Takada , Takayuki Nabeshima , Hideaki Koizumi
发明人： Atsumu Hirabayashi , Yukiko Hirabayashi , Minoru Sakairi , Yasuaki Takada , Takayuki Nabeshima , Hideaki Koizumi
IPC分类号： G01N27/62 , G01N27/447 , G01N30/72 , H01J49/04 , H01J49/10
CPC分类号： G01N30/7266 , H01J49/0468 , H01J49/167
摘要： A mass spectrometer comprising a passage through which a sample solution flows, the passage including a capillary having an open tip, the sample solution flowing through the capillary out of the open tip of the capillary, a gas passage which forms a gas flow around the open tip of the capillary, the gas flow spraying the sample solution flowing out of the open tip of the capillary, a first electrode which contacts the sample solution flowing in the passage and applies an electric potential to the sample solution flowing in the passage, a second electrode disposed around the capillary near the open tip of the capillary, the second electrode being downstream from the first electrode with respect to a direction in which the sample solution flows in the passage, there being no gap extending downstream from the open tip of the capillary to the second electrode in a direction in which the sample solution flows out of the open tip of the capillary, the second electrode being electrically isolated from the sample solution flowing in the capillary and applying an electric field to the sample solution flowing in the capillary, and an analyzer which analyzes a mass of gaseous ions formed from the sample solution sprayed by the gas flow.
摘要翻译：一种质谱仪，包括样品溶液流过的通道，所述通道包括具有开口尖端的毛细管，所述样品溶液从毛细管的开口尖端流过毛细管，气体通道围绕开口形成气流毛细管的尖端，气流喷射从毛细管的开口尖端流出的样品溶液，第一电极，其接触在通道中流动的样品溶液，并向在通道中流动的样品溶液施加电位，第二电极设置在毛细管附近的毛细管周围的电极，第二电极相对于样品溶液在通道中流动的方向从第一电极下游，在毛细管的开口尖端的下游没有间隙在样品溶液从毛细管的开口尖端流出的方向到第二电极，第二电极是电隔离的从在毛细管中流动的样品溶液流出并向在毛细管中流动的样品溶液施加电场，以及分析器，其分析由气流喷射的样品溶液形成的气态离子的质量。

2. 发明授权

US5898175A Mass spectrometer and mass spectrometry method for analyzing compounds contained in a solution 失效
标题翻译：用于分析溶液中所含化合物的质谱仪和质谱法
公开(公告)号：US5898175A
公开(公告)日：1999-04-27
申请号：US708415
申请日：1996-09-05
申请人： Atsumu Hirabayashi , Yukiko Hirabayashi , Minoru Sakairi , Yasuaki Takada , Takayuki Nabeshima , Hideaki Koizumi
发明人： Atsumu Hirabayashi , Yukiko Hirabayashi , Minoru Sakairi , Yasuaki Takada , Takayuki Nabeshima , Hideaki Koizumi
IPC分类号： G01N27/62 , G01N27/447 , G01N30/72 , H01J49/04 , H01J49/10
CPC分类号： G01N30/7266 , H01J49/0468 , H01J49/167
摘要： A mass spectrometer employing an ion source includes a capillary for spraying therethrough liquid into the atmospheres and an orifice through which a portion in the vicinity of a tip of the capillary is inserted, the orifice being designed in such a way that gases are caused to flow up to the tip of the capillary along a peripheral wall face of the capillary. The flow rate of gas in the vicinity of the tip of the capillary is about the sonic velocity, and a voltage is applied across the liquid flowing through the capillary and the orifice or an electrode arranged in the vicinity of the tip of the capillary.
摘要翻译：使用离子源的质谱仪包括用于将液体喷射到气氛中的毛细管和插入毛细管的尖端附近的部分的孔，孔被设计成使气体流动直到毛细管的尖端沿着毛细管的周壁面。毛细管尖端附近的气体的流速大约是声速，并且在流过毛细管的液体和布置在毛细管尖端附近的孔或电极之间施加电压。

3. 发明授权

US06437327B2 Mass spectrometry of solution and apparatus therefor 有权
标题翻译：溶液质谱仪及其设备
公开(公告)号：US06437327B2
公开(公告)日：2002-08-20
申请号：US09859508
申请日：2001-05-18
申请人： Yasuaki Takada , Minoru Sakairi , Atsumu Hirabayashi , Takayuki Nabeshima , Hideaki Koizumi
发明人： Yasuaki Takada , Minoru Sakairi , Atsumu Hirabayashi , Takayuki Nabeshima , Hideaki Koizumi
IPC分类号： H01J4910
CPC分类号： H01J49/165 , G01N30/7266 , H01J49/168
摘要： A mass spectrometer including a sprayer for spraying a sample solution, a needle electrode for ionizing the sample contained in the sample solution, an aperture for introducing the ions of the sample into a lower pressure region having a pressure lower than the pressure of a region in which the needle electrode is disposed, and a mass spectrometric apparatus for analyzing the ions introduced from the aperture. A direction of a spray caused by the sprayer is almost perpendicular to or at an angle with respect to a center axis of the aperture, and a tip of the needle is disposed facing to an electrode having the aperture.
摘要翻译：一种质谱仪，包括用于喷射样品溶液的喷雾器，用于使包含在样品溶液中的样品电离的针状电极，用于将样品的离子引入低于区域压力的低压区域的孔设置针状电极的质谱仪和用于分析从孔径引入的离子的质谱仪。由喷雾器引起的喷雾方向几乎与孔的中心轴垂直或成一定角度，并且针的尖端面向具有孔的电极。

4. 发明授权

US06252225B1 Mass spectrometry of solution and apparatus therefor 有权
标题翻译：溶液质谱仪及其设备
公开(公告)号：US06252225B1
公开(公告)日：2001-06-26
申请号：US09492352
申请日：2000-01-27
申请人： Yasuaki Takada , Minoru Sakairi , Atsumu Hirabayashi , Takayuki Nabeshima , Hideaki Koizumi
发明人： Yasuaki Takada , Minoru Sakairi , Atsumu Hirabayashi , Takayuki Nabeshima , Hideaki Koizumi
IPC分类号： H01J4910
CPC分类号： H01J49/165 , G01N30/7266 , H01J49/168
摘要： A mass spectrometer including a sprayer for spraying a sample solution, a needle electrode for ionizing the sample contained in the sample solution, an aperture for introducing the ions of the sample into a lower pressure region having a pressure lower than the pressure of a region in which the needle electrode is disposed, and a mass spectrometric apparatus for analyzing the ions introduced from the aperture. A direction of a spray caused by the sprayer is almost perpendicular to a center axis of the aperture and a tip of the needle is disposed facing to an electrode having the aperture.
摘要翻译：一种质谱仪，包括用于喷射样品溶液的喷雾器，用于使包含在样品溶液中的样品电离的针状电极，用于将样品的离子引入低于区域压力的低压区域的孔设置针状电极的质谱仪和用于分析从孔径引入的离子的质谱仪。由喷雾器引起的喷雾方向几乎垂直于孔的中心轴线，并且针的尖端面向具有孔的电极设置。

5. 发明授权

US6121608A Mass spectrometry of solution and apparatus 失效
标题翻译：溶液和仪器质谱
公开(公告)号：US6121608A
公开(公告)日：2000-09-19
申请号：US968898
申请日：1997-11-06
申请人： Yasuaki Takada , Minoru Sakairi , Atsumu Hirabayashi , Takayuki Nabeshima , Hideaki Koizumi
发明人： Yasuaki Takada , Minoru Sakairi , Atsumu Hirabayashi , Takayuki Nabeshima , Hideaki Koizumi
IPC分类号： G01N27/62 , B01D59/44 , G01N30/72 , H01J49/00 , H01J49/04 , H01J49/10
CPC分类号： H01J49/165 , G01N30/7266 , H01J49/168
摘要： A mass spectrometric apparatus includes a device for supplying a sample solution to an outlet, the sample solution including a solvent and a solute, a first ionization device for receiving the sample solution from the outlet and electrospraying the received sample solution, thereby ionizing at least a portion of the received sample solution, a second ionization device for receiving at least a portion of the electrosprayed sample solution produced by the first ionization device and ionizing at least a portion of the received electrospayed sample solution, thereby producing ions, and a mass spectrometric device for receiving at least some of the ions produced by the second ionization device and analyzing masses of the received ions.
摘要翻译：质谱装置包括用于将样品溶液供应到出口的装置，所述样品溶液包括溶剂和溶质，用于从所述出口接收样品溶液并对所接收的样品溶液进行电喷雾的第一离子化装置，从而将至少一种接收样品溶液的一部分，第二电离装置，用于接收由第一离子化装置产生的电喷雾样品溶液的至少一部分，并且电离至少一部分接收的电喷雾样品溶液，从而产生离子，以及质谱仪用于接收由第二电离装置产生的至少一些离子并分析所接收的离子的质量。

6. 发明授权

US06180941B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US06180941B2
公开(公告)日：2001-01-30
申请号：US09447578
申请日：1999-11-23
申请人： Yasuaki Takada , Minoru Sakairi , Takayuki Nabeshima , Yukiko Hirabayashi , Hideaki Koizumi
发明人： Yasuaki Takada , Minoru Sakairi , Takayuki Nabeshima , Yukiko Hirabayashi , Hideaki Koizumi
IPC分类号： H01J4942
CPC分类号： H01J49/067 , H01J49/04
摘要： A mass spectrometer comprising an ionization means for ionizing sample compounds to be analyzed mass spectro-scopically in an atmospheric pressure, a sample solution supply means for supplying a solution containing the sample compounds to the ionization means, means for feeding the ions formed by the ionization means through an aperture disposed in an electrode into a vacuum region, and an ion trap type mass spectroscopic means for mass spectroscopically analyzing ions entered through the aperture into the vacuum region, in which an ion decelerating electric field forming means is disposed between the electrode disposed with the aperture and an electrode disposed with an ion entrance opening for entering the ions into the ion trap type mass spectroscopic means for forming an electric field for decelerating the ions, and the ions injected to the ion trap mass spectroscopic means is lowered. This facilitates accumulation ions in the ion trap mass spectralyzing means even if a high drift voltage is used thereby enabling high sensitivity analysis for polar compounds such as peptides.
摘要翻译：一种质谱仪，其特征在于，包括：离子化装置，用于将大气压力分析分析的样品化合物离子化;将含有样品化合物的溶液供给到电离装置的样品溶液供给装置，意味着通过设置在电极中的孔进入真空区域，以及离子阱型质谱分析装置，用于质谱分析通过孔进入真空区域的离子，其中离子减速电场形成装置设置在设置的电极之间其中所述孔和电极设置有离子入口，用于将离子进入离子阱型质谱分析装置，用于形成用于使离子减速的电场，并且注入离子阱质谱分析装置的离子降低。即使使用高漂移电压，这也有助于离子阱质谱分析手段中的积聚离子，从而能够对极性化合物如肽进行高灵敏度分析。

7. 发明授权

US5969351A Mass spectrometer 失效
标题翻译：质谱仪
公开(公告)号：US5969351A
公开(公告)日：1999-10-19
申请号：US796548
申请日：1997-02-06
申请人： Takayuki Nabeshima , Minoru Sakairi , Yasuaki Takada , Yukiko Hirabayashi , Hideaki Koizumi
发明人： Takayuki Nabeshima , Minoru Sakairi , Yasuaki Takada , Yukiko Hirabayashi , Hideaki Koizumi
IPC分类号： H01J49/04 , H01J49/28
CPC分类号： H01J49/168 , H01J49/0404 , H01J49/049 , G01N30/726
摘要： A semi-micro liquid chromatograph/mass spectrometer apparatus has an ion source. The space from the end portion of a flow passage of a liquid chromatograph shell to a vaporization portion is closed so as to prevent the inflow of a gas from outside the ion source into the space. Further, the nebulization and vaporization portions are joined together and heated by a common heater. Dilution of a sample to be analyzed is prevented, and high sensitivity detection becomes possible in a low velocity liquid chromatograph/mass spectrometer.
摘要翻译：半微量液相色谱仪/质谱仪装置具有离子源。从液相色谱仪壳体的流路端部到气化部分的空间被封闭，以防止从离子源外部的气体流入空间。此外，将雾化和蒸发部分接合在一起并通过公共加热器加热。防止要分析的样品的稀释，并且可以在低速液相色谱仪/质谱仪中进行高灵敏度检测。

8. 发明授权

US6075243A Mass spectrometer 失效
标题翻译：质谱仪
公开(公告)号：US6075243A
公开(公告)日：2000-06-13
申请号：US827184
申请日：1997-03-27
申请人： Takayuki Nabeshima , Minoru Sakairi , Yasuaki Takada , Yukiko Hirabayashi , Hideaki Koizumi
发明人： Takayuki Nabeshima , Minoru Sakairi , Yasuaki Takada , Yukiko Hirabayashi , Hideaki Koizumi
IPC分类号： G01N27/62 , G01N30/72 , H01J49/02 , H01J49/26 , H01J49/42 , B01D59/44 , H01J49/00
CPC分类号： H01J49/424 , H01J49/044 , H01J49/4255
摘要： A mass spectrometer in which, in order to reduce noise due to other particles (large charge droplets, neutral particles, photons, or the like), the orbit of ions and the orbit of other particles are separated from each other in the inside of a mass analysis region so as to make it possible to prevent the other particles from reaching an ion detection region without using any deflector.
摘要翻译：一种质谱仪，其中为了减少由于其它颗粒（大电荷液滴，中性粒子，光子等）引起的噪声，离子的轨道和其它颗粒的轨道在一个质量分析区域，使得可以防止其他颗粒在不使用任何偏转器的情况下到达离子检测区域。

9. 发明授权

US06465779B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US06465779B2
公开(公告)日：2002-10-15
申请号：US09968928
申请日：2001-10-03
申请人： Yasuaki Takada , Minoru Sakairi , Takayuki Nabeshima , Yukiko Hirabayashi , Hideaki Koizumi
发明人： Yasuaki Takada , Minoru Sakairi , Takayuki Nabeshima , Yukiko Hirabayashi , Hideaki Koizumi
IPC分类号： H01J4942
CPC分类号： H01J49/067 , H01J49/04
摘要： A mass spectrometer comprising an ionization means for ionizing sample compounds to be analyzed mass spectroscopically in an atmospheric pressure, a sample solution supply means for supplying a solution containing the sample compounds to the ionization means, means for feeding the ions formed by the ionization means through an aperture disposed in an electrode into a vacuum region, and an ion trap type mass spectroscopic means for mass spectroscopically analyzing ions entered through the aperture into the vacuum region, in which an ion decelerating electric field forming means is disposed between the electrode disposed with the aperture and an electrode disposed with an ion entrance opening for entering the ions into the ion trap type mass spectroscopic means for forming an electric field for decelerating the ions, and the ions injected to the ion trap mass spectroscopic means is lowered. This facilitates accumulation ions in the ion trap mass spectralyzing means even if a high drift voltage is used thereby enabling high sensitivity analysis for polar compounds such as peptides.
摘要翻译：一种质谱仪，其特征在于，包括：离子化装置，用于在大气压下对质谱进行质谱分析的样品化合物进行离子化;将含有所述样品化合物的溶液供给到所述电离装置的样品溶液供给装置，将由所述电离装置形成的离子供给将设置在电极中的孔设置在真空区域中，以及离子阱型质谱分析装置，用于对通过孔进入真空区域的离子进行质谱分析，其中离子减速电场形成装置设置在孔和设置有离子入口的电极，用于将离子进入离子阱型质谱分析装置，用于形成用于使离子减速的电场，并且注入离子阱质谱分析装置的离子降低。即使使用高漂移电压，这也有助于离子阱质谱分析手段中的积聚离子，从而能够对极性化合物如肽进行高灵敏度分析。

10. 发明授权

US06316769B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US06316769B2
公开(公告)日：2001-11-13
申请号：US09739217
申请日：2000-12-19
申请人： Yasuaki Takada , Minoru Sakairi , Takayuki Nabeshima , Yukiko Hirabayashi , Hideaki Koizumi
发明人： Yasuaki Takada , Minoru Sakairi , Takayuki Nabeshima , Yukiko Hirabayashi , Hideaki Koizumi
IPC分类号： H01J4942
CPC分类号： H01J49/067 , H01J49/04
摘要： A mass spectrometer comprising an ionization means for ionizing sample compounds to be analyzed mass spectro-scopically in an atmospheric pressure, a sample solution supply means for supplying a solution containing the sample compounds to the ionization means, means for feeding the ions formed by the ionization means through an aperture disposed in an electrode into a vacuum region and a ion trap type mass spectroscopic means for mass spectroscopically analyzing ions entered through the aperture into the vacuum region, in which an ion decelerating electric field forming means is disposed between the electrode disposed with the aperture and an electrode disposed with an ion entrance opening for entering the ions into the ion trap type mass spectroscopic means for forming an electric field for decelerating the ions, and the ions injected to the ion trap mass spectroscopic means is lowered. This facilitates accumulation ions in the ion trap mass spectralyzing means even if a high drift voltage is used thereby enabling high sensitivity analysis for polar compounds such as peptides.
摘要翻译：一种质谱仪，其特征在于，包括：离子化装置，用于将大气压力分散分析的样品化合物离子化;将含有样品化合物的溶液供给到电离装置的样品溶液供给装置，意味着通过设置在电极中的孔进入真空区域和离子阱型质谱分析装置，用于质谱分析通过孔进入真空区域的离子，其中离子减速电场形成装置设置在设置有所述孔和电极设置有离子入口，用于将离子进入离子阱型质谱分析装置，用于形成用于使离子减速的电场，以及注入离子阱质谱分析装置的离子。即使使用高漂移电压，这也有助于离子阱质谱分析手段中的积聚离子，从而能够对极性化合物如肽进行高灵敏度分析。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式