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    • 3. 发明授权
    • Detection of HLA-DR
    • HLA-DR的检测
    • US5939542A
    • 1999-08-17
    • US931072
    • 1997-09-15
    • Shintaro KawaiShinji MaekawajiriHirotaka Nakamoto
    • Shintaro KawaiShinji MaekawajiriHirotaka Nakamoto
    • C12Q1/68C07H21/04
    • C12Q1/6881
    • A probe set is provided which can assay larger amounts of samples in a simpler manner and enables typing of all HLA-DR types currently known to be present in Japanese. The probe set comprises part or all of oligonucleotides having the following sequences 1 to 16 or complementary strands thereof:sequence 1: CGGTTGCTCGGAAAGATGCATCsequence 2: ACACTCCCTCTTTGGCTGsequence 3: GGCCGGGTGGACAACTACsequence 4: ATGTTTAACCTGCTCCAAsequence 5: CCTGATGAGGAGTACTGGAAsequence 6: AGCTACTGCGCTTCGACsequence 7: CGTAGAGTACTCCAAGAAsequence 8: CTTATACTTACCCTGCCAsequence 9: AGACAGGCGGGCCCTsequence 10: TCAAACTTATCCTGCTTCsequence 11: AAACTTAACCTCCTCCAAsequence 12: ACTCTACGTCTGAGTGTCsequence 13: ACGGGTGAGTGTTATTTCsequence 14: GACCTCCTGGAAGACAGGsequence 15: ACATCCTGGAAGACGAGCsequence 16: CCCGTAGTTGTGTCTGCA.
    • 提供了一种探针组,其可以以更简单的方式测定更大量的样品,并且能够打印目前已知以日语存在的所有HLA-DR类型。 探针组包含具有以下序列1至16或其互补链的部分或全部寡核苷酸:序列1:CGGTTGCTCGGAAAGATGCATC序列2:ACACTCCCTCTTTGGCTG序列3:GGCCGGGTGGACAACTAC序列4:ATGTTTAACCTGCTCCAA序列5:CCTGATGAGGAGTACTGGAA序列6:AGCTACTGCGCTTCGAC序列7:CGTAGAGTACTCCAAGAA序列 8:CTTATACTTACCCTGCCA序列9:AGACAGGCGGGCCCT序列10:TCAAACTTATCCTGCTTC序列11:AAACTTAACCTCCTCCAA序列12:ACTCTACGTCTGAGTGTC序列13:ACGGGTGAGTGTTATTTC序列14:GACCTCCTGGAAGACAGG序列15:ACATCCTGGAAGACGAGC序列16:CCCGTAGTTGTGTCTGCA。