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1. 发明授权

US09551654B2 Method for the spectral identification of microorganisms 有权
标题翻译：微生物光谱鉴定方法
公开(公告)号：US09551654B2
公开(公告)日：2017-01-24
申请号：US11630856
申请日：2005-06-30
申请人： Ashraf Ismail , Jonah Prevost Kirkwood , Jacqueline Sedman , Andrew Ghetler , Tom Pinchuk , John Austin , Lorraine Gour
发明人： Ashraf Ismail , Jonah Prevost Kirkwood , Jacqueline Sedman , Andrew Ghetler , Tom Pinchuk , John Austin , Lorraine Gour
IPC分类号： G01N33/48 , G01N33/50 , G01N21/3563 , G06F19/18 , G06F19/12 , G01N21/17 , G01N21/35
CPC分类号： G01N21/3563 , G01N2021/1748 , G01N2021/1772 , G01N2021/3595 , G01N2201/129 , G06F19/12 , G06F19/18
摘要： A rapid method for characterizing and identifying microorganisms using Focal-Plane Array (FPA)-Fourier Transform Infrared (FTIR) spectroscopy is disclosed. Multi-pixels spectral images of unknown microorganisms spectra are analyzed and compared to spectra of reference microorganisms in databases. The method allows rapid and highly reliable identification of unknown microorganisms for the purpose of medical diagnosis, food and environmental control.
摘要翻译：公开了使用焦平面阵列（FPA） - 傅里叶变换红外（FTIR）光谱法表征和鉴定微生物的快速方法。分析未知微生物光谱的多像素光谱图像，并与数据库中参考微生物的光谱进行比较。该方法允许快速和高度可靠地鉴定未知微生物，用于医学诊断，食品和环境控制。

2. 发明申请

US20080132418A1 Method for the Spectral Identification of Microorganisms 有权
标题翻译：微生物光谱鉴定方法
公开(公告)号：US20080132418A1
公开(公告)日：2008-06-05
申请号：US11630856
申请日：2005-06-30
申请人： Ashraf Ismail , Jonah Prevost Kirkwood , Jacqueline Sedman , Andrew Ghetler , Tom Pinchuk
发明人： Ashraf Ismail , Jonah Prevost Kirkwood , Jacqueline Sedman , Andrew Ghetler , Tom Pinchuk
IPC分类号： C40B20/08 , C12Q1/04 , C40B40/02 , C12Q1/70
CPC分类号： G01N21/3563 , G01N2021/1748 , G01N2021/1772 , G01N2021/3595 , G01N2201/129 , G06F19/12 , G06F19/18
摘要： A rapid method for characterizing and identifying microorganisms using Focal-Plane Array (FPA)-Fourier Transform Infrared (FTIR) spectroscopy is disclosed. Multi-pixels spectral images of unknown microorganisms spectra are analyzed and compared to spectra of reference microorganisms in databases. The method allows rapid and highly reliable identification of unknown microorganisms for the purpose of medical diagnosis, food and environmental control.
摘要翻译：公开了使用焦平面阵列（FPA） - 傅里叶变换红外（FTIR）光谱法表征和鉴定微生物的快速方法。分析未知微生物光谱的多像素光谱图像，并与数据库中参考微生物的光谱进行比较。该方法允许快速和高度可靠地鉴定未知微生物，用于医学诊断，食品和环境控制。

3. 发明申请

US20070087023A1 Polymer-Based Antimicrobial Agents, Methods of Making Said Agents, and Applications Using Said Agents 审中-公开
标题翻译：基于聚合物的抗微生物剂，制备所述试剂的方法和使用所述试剂的应用
公开(公告)号：US20070087023A1
公开(公告)日：2007-04-19
申请号：US11558027
申请日：2006-11-09
申请人： Ashraf Ismail , Leonard Pinchuk , Orley Pinchuk , David Pinchuk
发明人： Ashraf Ismail , Leonard Pinchuk , Orley Pinchuk , David Pinchuk
IPC分类号： A01N59/16 , A01N25/00
CPC分类号： A01N59/16 , A01N59/20 , A01N25/10 , A01N2300/00
摘要： The present invention relates to antimicrobial agents, methods for the production of these agents, and the use of these agents. The antimicrobial agent of the present invention includes a water-soluble polymer and oligodynamic metal ions which interact with counter-ions of the polymer such that the metal ions are bound to corresponding counter-ions. The polymer controls a sustained release of the metal ions. The metal ions preferably include small size metal particles (e.g., nano-sized silver particles) that interact to the water-soluble polymer as well as metal ions derived from one or more water-soluble oligodynamic metal compositions (e.g., metal sulfates and/or metal nitrates). The agent may also include one or more acids, including organic acids and/or non-organic acids. In another aspect, antimicrobial agents that include a polymer and oligodynamic metal ions are used to treat or prevent citrus canker.
摘要翻译：本发明涉及抗微生物剂，这些制剂的制备方法以及这些试剂的用途。本发明的抗微生物剂包括与聚合物的抗衡离子相互作用的水溶性聚合物和低分子量金属离子，使得金属离子与相应的抗衡离子结合。聚合物控制金属离子的持续释放。金属离子优选包括与水溶性聚合物相互作用的小尺寸金属颗粒（例如，纳米尺寸的银颗粒）以及衍生自一种或多种水溶性低分子量金属组合物的金属离子（例如，金属硫酸盐和/或金属硝酸盐）。该试剂还可以包括一种或多种酸，包括有机酸和/或非有机酸。另一方面，包括聚合物和低分子动力学金属离子的抗微生物剂用于治疗或预防柑橘溃疡。

4. 发明申请

US20070092632A1 Ultra high pressure modified proteins and uses thereof 审中-公开
标题翻译：超高压改性蛋白及其用途
公开(公告)号：US20070092632A1
公开(公告)日：2007-04-26
申请号：US11255265
申请日：2005-10-21
申请人： Stan Kubow , Larry Lands , Laurie Chan , Charles Rohlicek , Ashraf Ismail , Hosahalli Ramaswamy , Pedro Alvarez , Vijay Grey
发明人： Stan Kubow , Larry Lands , Laurie Chan , Charles Rohlicek , Ashraf Ismail , Hosahalli Ramaswamy , Pedro Alvarez , Vijay Grey
IPC分类号： A23J1/00
CPC分类号： A23J3/08 , A23J3/16 , A23L33/17 , A23V2002/00 , A61K35/20 , A23V2300/46
摘要： The present invention is a method for increasing the digestibility of a food protein by subjecting the food protein to a single-cycle of ultra high pressure. Food proteins of the instant invention find application in nutraceutical, nutritional food, nutritional product or dietary supplement compositions for providing a protein source to a subject with a protein deficiency. In particular embodiments, the food protein is a whey protein useful in preventing or treating diseases or conditions associated with glutathione deficiency.
摘要翻译：本发明是通过使食品蛋白质进行超高压单循环来提高食品蛋白质的消化率的方法。本发明的食品蛋白质可用于营养食品，营养食品，营养产品或膳食补充剂组合物中，以向具有蛋白质缺乏的受试者提供蛋白质来源。在具体实施方案中，食物蛋白质是可用于预防或治疗与谷胱甘肽缺乏相关的疾病或病症的乳清蛋白。

5. 发明授权

US5422283A Solid-phase interferometric immunoassay system 失效
标题翻译：固相干涉免疫测定系统
公开(公告)号：US5422283A
公开(公告)日：1995-06-06
申请号：US185170
申请日：1994-01-24
申请人： Ashraf Ismail
发明人： Ashraf Ismail
IPC分类号： G01N21/35 , G01N33/543 , G01N33/53 , G01B9/02 , G01N33/546 , G01N33/552
CPC分类号： G01N33/54373 , Y10S435/808 , Y10S435/973
摘要： The present invention relates to a solid-phase immunoassay system for the determination of an antibody or an antigen in a sample which consists of an interferometric signal from an optical source, a solid support coated with an antibody or an antigen and having at least one region immersed in a solution containing a sample, thereby the corresponding antigen or antibody can be complexed on the solid support, an optical transfer and focusing system to measure the interferometric signal after its transmission (or reflectance) by the solid support, and a measuring device to record and process the interferometric signal at a wavelength corresponding to an absorption characteristic of the antigen-antibody complex or of a label incorporated into the antigen-antibody complex, thereby determining the amount of antigen or antibody in the sample.
摘要翻译：本发明涉及用于测定样品中的抗体或抗原的固相免疫测定系统，其由来自光源的干涉信号，涂覆有抗体或抗原的固体支持物组成，并具有至少一个区域浸入含有样品的溶液中，从而相应的抗原或抗体可以复合在固体支持物上，光学转移和聚焦系统，用于在固体支持物传播（或反射）之后测量干涉信号，并将测量装置以对应于抗原 - 抗体复合物或掺入抗原 - 抗体复合物的标签的吸收特性的波长记录和处理干涉信号，从而确定样品中抗原或抗体的量。

6. 发明申请

US20070098806A1 Polymer-Based Antimicrobial Agents, Methods of Making Said Agents, and Products Incorporating Said Agents 失效
标题翻译：基于聚合物的抗微生物剂，制备所述试剂的方法和掺入所述试剂的产品
公开(公告)号：US20070098806A1
公开(公告)日：2007-05-03
申请号：US11558023
申请日：2006-11-09
申请人： Ashraf Ismail , Leonard Pinchuk , Orley Pinchuk , David Pinchuk
发明人： Ashraf Ismail , Leonard Pinchuk , Orley Pinchuk , David Pinchuk
IPC分类号： A61K9/14
CPC分类号： A61K9/145 , Y10S604/905
摘要： The present invention relates to antimicrobial agents, methods for the production of these agents, and the use of these agents. The antimicrobial agent of the present invention includes a water-soluble polymer and oligodynamic metal ions which interact with counter-ions of the polymer such that the metal ions are bound to corresponding counter-ions. The water-soluble polymer controls a sustained release of the metal ions. The oligodynamic metal ions preferably include small size metal particles (e.g., nano-sized silver particles) that interact to the water-soluble polymer as well as metal ions derived from one or more water-soluble oligodynamic metal compositions (e.g., metal sulfates and/or metal nitrates). The agent may also include one or more acids, including organic acids (such as sulfates, carboxylic acids, amines, hydroxyls, nitrates, and phosphates) and/or non-organic acids (such as boric acid and dioctylborate).
摘要翻译：本发明涉及抗微生物剂，这些制剂的制备方法以及这些试剂的用途。本发明的抗微生物剂包括与聚合物的抗衡离子相互作用的水溶性聚合物和低分子量金属离子，使得金属离子与相应的抗衡离子结合。水溶性聚合物控制金属离子的持续释放。低分子金属离子优选包括与水溶性聚合物相互作用的小尺寸金属颗粒（例如，纳米尺寸的银颗粒）以及衍生自一种或多种水溶性低分子量金属组合物的金属离子（例如金属硫酸盐和/ 或金属硝酸盐）。该试剂还可以包括一种或多种酸，包括有机酸（例如硫酸盐，羧酸，胺，羟基，硝酸盐和磷酸盐）和/或非有机酸（例如硼酸和二辛酯硼酸盐）。

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