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1. 发明申请

US20070025890A1 Apparatus and method for administering a therapeutic agent into tissue 有权
标题翻译：将治疗剂施用于组织的装置和方法
公开(公告)号：US20070025890A1
公开(公告)日：2007-02-01
申请号：US11193339
申请日：2005-08-01
申请人： Ashok Joshi , James Steppan , Jesse Nachlas
发明人： Ashok Joshi , James Steppan , Jesse Nachlas
IPC分类号： B01J19/08
CPC分类号： A61M5/3129 , A61B17/3478 , A61B2017/00261 , A61M5/286 , A61M5/31511 , A61M37/00 , A61M2005/006 , A61M2005/3132 , A61M2202/0216 , C01B13/02 , C01B13/10 , C25B1/13
摘要： An apparatus for administering a therapeutic is provided. In various embodiments, the apparatus includes a syringe having a barrel and a plunger and having an ozone generator associated therewith. The generator is initiated and a therapeutic gas is accumulated within the barrel, at which point it can be delivered from the barrel into a target site via a needle, thereby delivering therapeutic effects to that target site.
摘要翻译：提供了一种用于施用治疗剂的装置。在各种实施例中，该装置包括具有镜筒和柱塞并且具有与其相关联的臭氧发生器的注射器。引发发生器并且治疗气体积聚在枪管内，此时它可以通过针从枪管输送到目标部位，从而将治疗效果传递给目标部位。

2. 发明申请

US20100307928A1 APPARATUS AND METHOD FOR ADMINISTERING A THERAPEUTIC AGENT INTO TISSUE 审中-公开
标题翻译：将治疗药物用于组织的装置和方法
公开(公告)号：US20100307928A1
公开(公告)日：2010-12-09
申请号：US12818664
申请日：2010-06-18
申请人： Ashok V. Joshi , James Steppan , Jesse Nachlas , Kieran P. Murphy
发明人： Ashok V. Joshi , James Steppan , Jesse Nachlas , Kieran P. Murphy
IPC分类号： C01B13/11 , C25B1/13
CPC分类号： A61M5/3129 , A61B17/3478 , A61B2017/00261 , A61M5/286 , A61M5/31511 , A61M37/00 , A61M2005/006 , A61M2005/3132 , A61M2202/0216 , C01B13/02 , C01B13/10 , C25B1/13
摘要： An apparatus for administering a therapeutic is provided. In various embodiments, the apparatus includes a syringe having a barrel and a plunger and having an ozone generator associated therewith. The generator is initiated and a therapeutic gas is accumulated within the barrel, at which point it can be delivered from the barrel into a target site via a needle, thereby delivering therapeutic effects to that target site.
摘要翻译：提供了一种用于施用治疗剂的装置。在各种实施例中，该装置包括具有镜筒和柱塞并且具有与其相关联的臭氧发生器的注射器。引发发生器并且治疗气体积聚在枪管内，此时它可以通过针从枪管输送到目标部位，从而将治疗效果传递给目标部位。

3. 发明申请

US20090038297A1 Ceramic Catalyst for NOx Oxidation and NOx Conversion in Emission Control Systems 审中-公开
标题翻译：用于排放控制系统中NOx氧化和NOx转化的陶瓷催化剂
公开(公告)号：US20090038297A1
公开(公告)日：2009-02-12
申请号：US11574502
申请日：2005-09-01
申请人： Balakrishnan Nair , Sai Bhavaraju , Jesse Nachlas , James Steppan
发明人： Balakrishnan Nair , Sai Bhavaraju , Jesse Nachlas , James Steppan
IPC分类号： F01N3/20 , B01J23/30 , B01J23/34 , B01J23/46 , B01J23/56 , B01J23/74
CPC分类号： B01J35/04 , B01D53/9422 , B01D53/944 , B01D53/9463 , B01D2255/102 , B01D2255/1026 , B01D2255/2042 , B01D2255/2073 , B01D2255/20776 , B01D2258/012 , B01D2258/014 , B01J23/462 , B01J23/6447 , B01J23/6527 , B01J23/6562 , B01J23/755 , B01J23/96 , B01J35/0006 , B01J37/0215
摘要： Ceramic catalytic compositions, systems, and methods for oxidizing, converting and/or removing NOxgas species present in gas streams such as exhaust gases are provided. The catalysts of the invention oxidize the nitrogen monoxide (NO) in gas streams to nitrogen dioxide (NO2), which may be adsorbed by a metal oxide or other NO2 adsorber. Catalysts suitable for use in systems of the present invention include ceramic oxides, mixtures of ceramic oxides, complex ceramic oxides, and mixtures of complex ceramic oxides. Such catalysts are shown herein to successfully achieve an NO-NO2 equilibrium gas composition at temperatures as low as 275° C. In addition, by using the catalyst with an NO2 adsorber, greater than 95% removal of combined NO and NO2 from the gas stream has been successfully demonstrated. Further, specific strategies have been identified to regenerate the catalyst system and restore performance after prolonged exposure to species such as sulfur dioxide (SO2).
摘要翻译：提供了用于氧化，转化和/或除去存在于气流如废气中的NOx气体的陶瓷催化组合物，系统和方法。本发明的催化剂将气流中的一氧化氮（NO）氧化成可被金属氧化物或其它NO 2吸附剂吸附的二氧化氮（NO 2）。适用于本发明体系的催化剂包括陶瓷氧化物，陶瓷氧化物的混合物，复合陶瓷氧化物以及复合陶瓷氧化物的混合物。这些催化剂在本文中显示，以在低至275℃的温度下成功地实现NO-NO 2平衡气体组合物。此外，通过使用催化剂与NO 2吸附器，从气流中去除大于95％的组合的NO和NO 2 已成功演示。此外，已经确定了特定的策略以再生催化剂体系并且在长时间暴露于物质如二氧化硫（SO2）之后恢复性能。

4. 发明授权

US08066659B2 Apparatus and method for treating and dispensing a material into tissue 有权
标题翻译：用于处理和分配材料到组织中的装置和方法
公开(公告)号：US08066659B2
公开(公告)日：2011-11-29
申请号：US11616041
申请日：2006-12-26
申请人： Ashok V. Joshi , James Steppan , Jesse Nachlas , Thomas A. Meaders , Kieran P. Murphy
发明人： Ashok V. Joshi , James Steppan , Jesse Nachlas , Thomas A. Meaders , Kieran P. Murphy
IPC分类号： A61M37/00 , B01J19/08 , B01J19/12
CPC分类号： A61B17/3478 , A61B2017/00261 , C01B13/02 , C01B13/10
摘要： An apparatus for administering a therapeutic is provided. In various embodiments, the apparatus includes a syringe having a barrel and a plunger and having a material treatment module associated therewith. The material treatment module may be an ozone generator that is initiated such that material containing ozone accumulates within the barrel. The material can then be delivered from the barrel into a target site via a needle, thereby delivering therapeutic effects to that target site.
摘要翻译：提供了一种用于施用治疗剂的装置。在各种实施例中，该装置包括具有镜筒和柱塞并且具有与其相关联的材料处理模块的注射器。材料处理模块可以是启动的臭氧发生器，使得含有臭氧的材料在桶内积聚。然后可以通过针将材料从筒输送到目标部位，由此向该目标部位输送治疗效果。

5. 发明申请

US20120022437A1 APPARATUS AND METHOD FOR TREATING AND DISPENSING A MATERIAL INTO TISSUE 审中-公开
标题翻译：用于处理和分配材料进入组织的装置和方法
公开(公告)号：US20120022437A1
公开(公告)日：2012-01-26
申请号：US13188999
申请日：2011-07-22
申请人： Ashok Joshi , James Stephan , Jesse Nachlas , Thomas A. Meaders , Kieran P. Murphy
发明人： Ashok Joshi , James Stephan , Jesse Nachlas , Thomas A. Meaders , Kieran P. Murphy
IPC分类号： A61M37/00 , A61M5/31
CPC分类号： A61B17/3478 , A61B2017/00261 , C01B13/02 , C01B13/10
摘要： A method for administering a therapeutic is provided. In various embodiments, the method includes providing a handheld dispensing apparatus comprising a housing defining a chamber, a material treatment module in material communication with the chamber, an outlet in material communication with the chamber, and a needle in material communication with the outlet for releasing the material from the housing. The method includes collecting a precursor material in the chamber, activating the material treatment module, treating the precursor material collected in the chamber with the material treatment module to create a treated material, positioning the needle in a body, and dispensing the treated material out of the apparatus into the body.
摘要翻译：提供了治疗剂的给药方法。在各种实施例中，该方法包括提供手持式分配装置，其包括限定腔室的壳体，与腔室材料连通的材料处理模块，与腔室材料连通的出口，以及与出口物质连通的针头，用于释放从房屋的材料。该方法包括在室中收集前体材料，启动材料处理模块，用材料处理模块处理收集在室中的前体材料，以产生经处理的材料，将针定位在主体中，并将经处理的材料从该装置进入身体。

6. 发明授权

US08591472B2 Apparatus for administering a therapeutic agent into tissue using a needle as the material treatment module 失效
标题翻译：用于使用针作为材料处理模块向组织施用治疗剂的装置
公开(公告)号：US08591472B2
公开(公告)日：2013-11-26
申请号：US13189290
申请日：2011-07-22
申请人： Ashok V. Joshi , James Steppan , Jesse Nachlas , Thomas A. Meaders , Kieran P. Murphy
发明人： Ashok V. Joshi , James Steppan , Jesse Nachlas , Thomas A. Meaders , Kieran P. Murphy
IPC分类号： A61M37/00 , A61M5/00
CPC分类号： A61B17/3478 , A61B2017/00261 , C01B13/02 , C01B13/10
摘要： An apparatus for administering a therapeutic is provided. In various embodiments, the apparatus includes a syringe having a barrel and a plunger and having a material treatment module associated with a needle. The material treatment module may be an ozone generator that is initiated such that material containing ozone accumulates within the needle. The material can then be delivered from the barrel into a target site via the needle, thereby delivering therapeutic effects to that target site.
摘要翻译：提供了一种用于施用治疗剂的装置。在各种实施例中，该装置包括具有镜筒和柱塞并且具有与针相关联的材料处理模块的注射器。材料处理模块可以是启动的臭氧发生器，使得含有臭氧的材料积聚在针内。然后可以通过针将材料从筒输送到目标部位，从而向该目标部位输送治疗效果。

7. 发明申请

US20100312171A1 APPARATUS AND METHOD FOR ADMINISTERING A THERAPEUTIC AGENT INTO TISSUE 审中-公开
公开(公告)号：US20100312171A1
公开(公告)日：2010-12-09
申请号：US12816787
申请日：2010-06-16
申请人： Ashok V. Joshi , James Steppan , Jesse Nachlas , Kieran P. Murphy
发明人： Ashok V. Joshi , James Steppan , Jesse Nachlas , Kieran P. Murphy
IPC分类号： A61M37/00
CPC分类号： A61M5/3129 , A61B17/3478 , A61B2017/00261 , A61M5/286 , A61M5/31511 , A61M37/00 , A61M2005/006 , A61M2005/3132 , A61M2202/0216 , C01B13/02 , C01B13/10 , C25B1/13
摘要： An apparatus for administering a therapeutic is provided. In various embodiments, the apparatus includes a syringe having a barrel and a plunger and having an ozone generator associated therewith. The generator is initiated and a therapeutic gas is accumulated within the barrel, at which point it can be delivered from the barrel into a target site via a needle, thereby delivering therapeutic effects to that target site.

8. 发明申请

US20060027465A1 NOx gas sensor method and device 有权
标题翻译： NOx气体传感器的方法和装置
公开(公告)号：US20060027465A1
公开(公告)日：2006-02-09
申请号：US11137693
申请日：2005-05-25
申请人： Balakrishnan Nair , Jesse Nachlas , Michael Middlemas
发明人： Balakrishnan Nair , Jesse Nachlas , Michael Middlemas
IPC分类号： G01N27/26
CPC分类号： G01N27/4074 , G01N33/0013 , G01N33/0037 , Y02A50/245
摘要： The present invention is a method and apparatus for measuring the total NOx concentration in a gas stream utilizing the principles of a NOx sensor, i.e., mixed potential sensor. The exhaust gas is first conditioned by a catalyst assembly that converts the various species of nitrogen oxide gases present to a fixed steady state concentration ratio of NO2/NO, where NO2 is approximately 0-10% of the total NOx concentration present in the gas exhaust, thereby enabling the NOx sensor to generate a meaningful and reproducible determination of the concentration of total NOx present in the gas being measured. The catalyst assembly also functions to oxidize any unburned combustibles such as CH4, CO, etc., and remove potential contaminants such as SO2.
摘要翻译：本发明是一种利用NO x传感器即混合电位传感器的原理测量气流中总NO x浓度的方法和装置。废气首先由催化剂组件调节，该催化剂组件将存在的各种氮氧化物气体转化为固定的NO 2 NO 2 / NO的稳态浓度比，其中NO 2 是气体排气中存在的总NO x x浓度的约0-10％，从而使得NO x传感器能够产生有意义且可重现的总浓度的确定存在于待测气体中的NO x。催化剂组合物还用于氧化任何未燃烧的可燃物如CH 4，CO等，并除去潜在的污染物如SO 2。

9. 发明授权

US08414752B2 Multilayer ceramic NOx gas sensor device 有权
标题翻译：多层陶瓷NOx气体传感器装置
公开(公告)号：US08414752B2
公开(公告)日：2013-04-09
申请号：US12610973
申请日：2009-11-02
申请人： Balakrishnan G. Nair , Jesse Nachlas
发明人： Balakrishnan G. Nair , Jesse Nachlas
IPC分类号： G01N27/407
CPC分类号： G01N27/4067
摘要： A mixed potential NOx sensor apparatus for measuring the total NOx concentration in a gas stream is disclosed. The NOx sensing apparatus comprises a multilayer ceramic structure with electrodes for sensing both oxygen and NOx gas concentrations and includes screen-printed metallized patterns that function to heat the ceramic sensing element to the proper temperature for optimum performance. This design may provide advantages over the existing technology by miniaturizing the sensing element to provide potentially faster sensor light off times and thereby reduce undesired exhaust gas emissions. By incorporating the heating source within the ceramic sensing structure, the time to reach the temperature of operation is shortened, and thermal gradients and stresses are minimized. These improvements may provide increased sensor performance, reliability, and lifetime.
摘要翻译：公开了一种用于测量气流中的总NOx浓度的混合型NOx传感器装置。 NOx感测装置包括具有用于感测氧气和NOx气体浓度的电极的多层陶瓷结构，并且包括用于将陶瓷感测元件加热到适当温度以获得最佳性能的丝网印刷金属化图案。该设计可以通过使感测元件小型化来提供优于现有技术的优点，以提供潜在的更快的传感器关灯时间，从而减少不期望的废气排放。通过将加热源并入陶瓷感应结构内，达到操作温度的时间缩短，并使热梯度和应力最小化。这些改进可以提供增加的传感器性能，可靠性和寿命。

10. 发明申请

US20090294285A1 Co-fired gas sensor 有权
标题翻译：联合燃气传感器
公开(公告)号：US20090294285A1
公开(公告)日：2009-12-03
申请号：US12155167
申请日：2008-05-30
申请人： Balakrishnan G. Nair , Jesse Nachlas , Gangqiang Wang
发明人： Balakrishnan G. Nair , Jesse Nachlas , Gangqiang Wang
IPC分类号： G01N27/26
CPC分类号： G01N27/4067
摘要： A sensor for detecting a gas is provided. The gas sensor may have a sensing section, a heating section, and a resistance temperature detector. The resistance temperature detector may be co-fired to be integral with at least one of the sensing section and the heating section.
摘要翻译：提供了一种用于检测气体的传感器。气体传感器可以具有感测部分，加热部分和电阻温度检测器。电阻温度检测器可以共烧以与感测部分和加热部分中的至少一个成一体。

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