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    • 1. 发明授权
    • Accommodating intraocular lens
    • 容纳人工晶状体
    • US06176878B1
    • 2001-01-23
    • US09213976
    • 1998-12-17
    • Arlene GwonDaniel G. Brady
    • Arlene GwonDaniel G. Brady
    • A61F216
    • A61F2/1613A61F2/1629
    • Intraocular lenses include an optic adapted to focus light toward a retina of an eye and a movement assembly coupled to the optic. The optic includes a far vision correction power for infinity reduced by a diopter power increment. The movement assembly is adapted to cooperate with the eye to move the optic bidirectionally, that is anteriorly in the eye and posteriorly in the eye, for example, from a neutral resting position in the eye, to effect positive accommodating movement of the optic and negative accommodating movement of the optic, respectively. Methods of inserting such intraocular lenses into an eye are also provided.
    • 人工晶状体包括适于将光聚焦到眼睛的视网膜的光学器件和耦合到光学元件的移动组件。 光学元件包括用屈光度功率增量减小的无限远视力校正功率。 运动组件适于与眼睛配合以使眼睛双向移动,即眼睛内部和眼睛中的后方,例如从眼睛中的中立静止位置移动视力,以实现光学和阴性的正面适应运动 分别容纳光学元件的运动。 还提供将眼内透镜插入眼睛的方法。
    • 4. 发明授权
    • Accommodating intraocular lens with elongated suspension structure
    • 容纳具有细长悬挂结构的人工晶状体
    • US07326246B2
    • 2008-02-05
    • US10342125
    • 2003-01-14
    • Daniel G. BradyArlene GwonRobert E. Glick
    • Daniel G. BradyArlene GwonRobert E. Glick
    • A61F2/16
    • A61F2/1613A61F2/1629A61F2/1694A61F2002/1681
    • An intraocular lens (IOL) for insertion in a capsular bag of an eye includes an optic for focusing light and a movement assembly coupled to the optic. The movement assembly is adapted to cooperate with the capsular bag to effect accommodating movement of the optic. The movement assembly includes one or more elongated fixation members coupled to a periphery of the optic and adapted to convert radial movement of the capsular bag to axial movement of the optic. The fixation members extend spirally at least half-way around the optic. Angled transition sections may be provided between each fixation member and the optic periphery. The anterior and posterior edges of the optic periphery may have relatively sharp angles to reduce epithelial cell growth.
    • 用于插入眼袋的眼内透镜(IOL)包括用于聚焦光的光学元件和耦合到光学元件的移动组件。 移动组件适于与胶囊袋配合以实现光学元件的容纳运动。 移动组件包括联接到光学元件的周边的一个或多个细长的固定构件,并且适于将囊袋的径向移动转换成光学元件的轴向移动。 固定构件至少在光学元件周围一半地螺旋延伸。 可以在每个固定构件和光学周边之间设置有角度的过渡部分。 光学周边的前边缘和后边缘可以具有相对尖锐的角度以减少上皮细胞生长。
    • 5. 发明授权
    • Anterior chamber intraocular lens having fixation members attached to the cornea and methods of implantation
    • 具有附着在角膜上的固定部件和植入方法的前房人工晶体镜
    • US06482229B1
    • 2002-11-19
    • US09717605
    • 2000-11-21
    • Arlene GwonDaniel G. Brady
    • Arlene GwonDaniel G. Brady
    • A61F216
    • A61F2/1605A61F2/16A61F2002/1681A61F2002/1683
    • An intraocular lens configured to be implanted in the cornea from the posterior aspect. The lens has an optic and a pair fixation members extending outward therefrom. One of the fixation members includes a single enlarged foot, while the other fixation member has two bifurcated feet. The fixation members are sized and shaped to fix within tunnels formed in the cornea. A method of the invention includes forming tunnels in the stroma layer of the cornea, and positioning the fixation members in the tunnels. The tunnels may be formed from outside or inside the cornea. The method may include inserting the folded intraocular lens into the anterior chamber, permitting the lens to unfold, inserting the fixation member with the enlarged foot in one of the tunnels, and bending the two bifurcated feet of the other fixation member together so as to fit within the other tunnel.
    • 构造成从后方植入角膜的眼内透镜。 透镜具有从其向外延伸的光学元件和一对固定构件。 一个固定构件包括单个放大的脚,而另一个固定构件具有两个分叉的脚。 固定构件的尺寸和形状适于固定在形成在角膜中的隧道内。 本发明的方法包括在角膜的基质层中形成隧道,并将固定构件定位在隧道内。 隧道可以从角膜外部或内部形成。 该方法可以包括将折叠的眼内透镜插入前房,允许透镜展开,将具有扩大的脚的固定构件插入其中一个隧道中,并将另一个固定构件的两个分叉的脚弯曲在一起以适合 在另一条隧道内。
    • 7. 发明申请
    • Hyaluronic acid in the enhancement of lens regeneration
    • 透明质酸增强镜片再生
    • US20060083732A1
    • 2006-04-20
    • US11293682
    • 2005-12-01
    • Arlene Gwon
    • Arlene Gwon
    • A61K38/47A61K31/728
    • A61K31/728A61K38/39A61K38/47A61K2300/00
    • The present invention addresses the treatment of ocular conditions by the enhancement of lens regeneration. This is accomplished by the administration of a high viscosity composition including a hyaluronic acid compound. Excess high viscosity composition may be removed by focal laser photophacoablation or through the use of a digestive compound or enzyme such as hyaluronidase. Additionally, a collagen product may be injected within the lens capsule to improve lens cell proliferation and differentiation, and to improve the configuration, shape and structure of regenerated lenses. Various embodiments involving the enhancement of lens regeneration are described. For example, lens regeneration may be enhanced by filling the lens capsule bag with the inventive hyaluronic acid compound; by inserting at least one collagen patch in the lens capsule; and/or by injecting a collagen-based product into the lens capsule.
    • 本发明通过增强透镜再生来处理眼睛状况。 这通过施用包含透明质酸化合物的高粘度组合物来实现。 过量的高粘度组合物可以通过聚焦激光光刻消除或通过使用消化化合物或酶如透明质酸酶来去除。 此外,可以将胶原产品注射到晶状体囊内以改善晶状体细胞增殖和分化,并且改善再生镜片的构型,形状和结构。 描述涉及增强透镜再生的各种实施例。 例如,可以通过用本发明的透明质酸化合物填充晶状体囊袋来增强透镜再生度; 通过在镜片胶囊中插入至少一个胶原蛋白贴片; 和/或通过将胶原蛋白基产品注射到镜片胶囊中。