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    • 1. 发明授权
    • Device for determining the concentration of at least one substance in
organic tissue
    • 用于确定有机组织中至少一种物质浓度的装置
    • US5243982A
    • 1993-09-14
    • US732401
    • 1991-07-18
    • Anton MostlMichael Mayer
    • Anton MostlMichael Mayer
    • A61B5/00A61M5/172
    • A61B5/14532A61M5/1723A61M2005/1726Y10S128/12
    • A device for determining the concentration of at least one substance in organic tissue includes a subcutaneous needle for insertion into the tissue and a pumping and suction unit which is controlled by a microprocessor and is used for delivering a perfusion fluid and draining it after its partial equilibration with the tissue. The device further includes a sensing unit connected to the microprocessor for determining the concentration of the substance to be analyzed and one or more marker variables. The perfusion fluid, a calibrating solution and at least one drug are provided in replaceable metering ampoules sealed with membranes, whose metering plungers can be actuated by a drive unit controlled by the microprocessor. The metering ampoules communicate with a master capillary leading from the pumping and suction unit to the subcutaneous needle; communication is established via capillary tubes piercing the membranes.
    • 用于确定有机组织中至少一种物质的浓度的装置包括用于插入组织的皮下针和由微处理器控制并用于输送灌注流体并在其部分平衡后排出的抽吸和抽吸单元 与组织。 该装置还包括连接到微处理器的感测单元,用于确定待分析物质的浓度和一个或多个标记变量。 在用膜密封的可更换的计量安瓿中提供灌注流体,校准溶液和至少一种药物,其计量柱塞可由由微处理器控制的驱动单元致动。 计量安瓿与从抽吸单元引导到皮下针的主毛细管连通; 通过穿透膜的毛细管建立通信。