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    • 4. 发明授权
    • Sunscreen compounds and compositions containing same and methods for use thereof
    • 防晒化合物和含有其的组合物及其使用方法
    • US07276230B2
    • 2007-10-02
    • US10744365
    • 2003-12-23
    • Anthony D. GonzalezAndrew H. PechkoGlen T. AndersonRobert E. Kalafsky
    • Anthony D. GonzalezAndrew H. PechkoGlen T. AndersonRobert E. Kalafsky
    • A61Q19/04A61Q19/00A61K8/02
    • A61K8/40A61K2800/52A61Q17/04
    • There is provided a photostable and synergistically enhanced topical sunscreen composition that provides increased substantivity, waterproofness, sweat resistance and rub off resistance. There is further provided methods of enhancing the photostability of a sunscreen active in a topical sunscreen composition, synergistically enhancing the UV absorbance of a topical sunscreen composition having a sunscreen active, and enhancing the substantivity, waterproofness, sweat resistance and rub off resistance in a topical sunscreen composition. The preferred compositions and methods have a sunscreen active, a cosmetically acceptable vehicle, and novel 2-substituted-3,3-diaryl-2-propenoic acid derivatives with [A] a C16 to C50 straight or branched chain, substituted or un-substituted, conjugated or non-conjugated hydrocarbon, or [B] a siloxane, polysiloxane, organo-modified polysiloxane residue, a group represented by the formula R10[Si(R10)2]n— and R11 which is a silicone residue derived from a silicone represented by the formula R11OH having a molecular weight up to about 30,000, wherein each R10 is independently selected from the group consisting of alkyl, alkoxy, aryl and aryloxy and n is from 1 to about 500.
    • 提供了一种光稳定和协同增强的局部防晒组合物,其提供增强的亲和性,防水性,耐汗性和耐擦性。 还提供了增强局部防晒组合物中防晒活性物质的光稳定性的方法,协同地增强了具有防晒活性的局部防晒组合物的紫外线吸光度,以及增强局部防晒组合物的亲和性,防水性,耐汗性和耐擦性 防晒组成。 优选的组合物和方法具有防晒活性物质,美容上可接受的载体和新的2-取代-3,3-二芳基-2-丙烯酸衍生物,其具有[A] C 16 C至C 50个直链或支链,取代或未取代的共轭或非共轭烃,或[B]硅氧烷,聚硅氧烷,有机改性聚硅氧烷残基,由式R 10表示的基团 [Si(R 10)2 N 2 - 和R 11是硅氧烷残基 衍生自分子量高达约30,000的由式R 11 OH表示的硅氧烷,其中每个R 10独立地选自烷基,烷氧基, 芳基和芳氧基,n为1至约500。