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1. 发明申请

US20100030242A1 SUTURING DEVICES AND METHODS FOR SUTURING AN ANATOMIC VALVE 有权
标题翻译：用于修复解剖阀的装置和方法
公开(公告)号：US20100030242A1
公开(公告)日：2010-02-04
申请号：US12463046
申请日：2009-05-08
申请人： Anthony A. Nobles , Benjamin G. Brosch , John R. Crew
发明人： Anthony A. Nobles , Benjamin G. Brosch , John R. Crew
IPC分类号： A61B17/12
CPC分类号： A61B17/0469 , A61B17/04 , A61B17/0482 , A61B2017/047 , A61B2017/0472 , A61B2017/0488 , A61B2017/06042 , A61B2017/06057
摘要： A device for suturing an anatomic valve can comprise an elongate body, a suture catch mechanism and a suture clasp arm. The suture catch mechanism can be operatively coupled to the elongate body for movement between a retracted position and an advanced position. The suture clasp arm can be attached to the elongate body for movement between a retracted position and an extended position. The suture clasp arm can comprise a suture clasp configured to releasably retain a suture portion. In some embodiments, the suture clasp is positioned on the suture clasp arm such that the suture catch mechanism retrieves the suture portion from the suture clasp arm while the arm is at least partially retracted. In some embodiments, the suture clasp arm can be closed about a tissue portion without damaging the tissue portion.
摘要翻译：用于缝合解剖瓣膜的装置可以包括细长主体，缝合线抓取机构和缝合线夹臂。缝合线锁定机构可以可操作地联接到细长主体，用于在缩回位置和前进位置之间移动。缝线夹臂可以连接到细长主体，以在缩回位置和延伸位置之间移动。缝合线夹臂可包括构造成可释放地保持缝线部分的缝线夹。在一些实施例中，缝合线扣被定位在缝合线钩臂上，使得缝合线抓住机构在臂至少部分缩回的同时从缝合线钩臂中取出缝线部分。在一些实施例中，缝合线夹臂可围绕组织部分封闭，而不损坏组织部分。

2. 发明授权

US08771296B2 Suturing devices and methods for suturing an anatomic valve 有权
标题翻译：用于缝合解剖瓣膜的缝合装置和方法
公开(公告)号：US08771296B2
公开(公告)日：2014-07-08
申请号：US12463046
申请日：2009-05-08
申请人： Anthony A. Nobles , Benjamin G. Brosch , John R. Crew
发明人： Anthony A. Nobles , Benjamin G. Brosch , John R. Crew
IPC分类号： A61B17/04 , A61B17/12
CPC分类号： A61B17/0469 , A61B17/04 , A61B17/0482 , A61B2017/047 , A61B2017/0472 , A61B2017/0488 , A61B2017/06042 , A61B2017/06057
摘要： A device for suturing an anatomic valve has an elongate body, a suture catch mechanism and a suture clasp arm. The suture catch mechanism is operatively coupled to the elongate body for movement between a retracted position and an advanced position. The suture clasp arm is pivotally attached to the elongate body for movement between a retracted position and an extended position. The suture clasp arm has a suture clasp configured to releasably retain a suture portion. In some embodiments, the suture clasp is positioned on the suture clasp arm such that the suture catch mechanism retrieves the suture portion from the suture clasp arm while the arm is at least partially retracted. In some embodiments, the suture clasp arm can be closed about a tissue portion without damaging the tissue portion.
摘要翻译：用于缝合解剖瓣膜的装置具有细长主体，缝合线捕获机构和缝合线夹臂。缝合线捕获机构可操作地联接到细长主体，用于在缩回位置和前进位置之间移动。缝线夹臂枢转地附接到细长主体以在缩回位置和延伸位置之间移动。缝合线夹臂具有构造成可释放地保持缝线部分的缝线夹。在一些实施例中，缝合线扣被定位在缝合线钩臂上，使得缝合线抓住机构在臂至少部分缩回的同时从缝合线钩臂中取出缝线部分。在一些实施例中，缝合线夹臂可围绕组织部分封闭，而不损坏组织部分。

3. 发明授权

US08348962B2 Suturing device and method 有权
标题翻译：缝合装置和方法
公开(公告)号：US08348962B2
公开(公告)日：2013-01-08
申请号：US11503652
申请日：2006-08-14
申请人： Anthony A. Nobles , Steven E. Decker , Benjamin G. Brosch
发明人： Anthony A. Nobles , Steven E. Decker , Benjamin G. Brosch
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/0491 , A61B17/06166 , A61B17/0625 , A61B2017/00637 , A61B2017/00659 , A61B2017/00663 , A61B2017/00672 , A61B2017/00867 , A61B2017/0472 , A61B2017/06042 , A61B2017/2911
摘要： A suturing device and method allows a physician to remotely suture biological tissue. The device includes an elongate body, first and second arms operably connected to the elongated body, whereby each arm mounts an end portion of a suture, and first and second needles, each needle having a distal end and being mounted such that the distal end of the needle is movable to engage respective end portions of suture. The suturing apparatus further includes an actuator which drives the needles to engage the suture. The suturing apparatus further includes an occluding device operably connected to the elongate body such that the occluding device may be advanced from the distal end of the elongate body to temporarily occlude the incision to be sutured.
摘要翻译：缝合装置和方法允许医生远程缝合生物组织。该装置包括细长主体，第一和第二臂可操作地连接到细长主体，由此每个臂安装缝合线的端部，以及第一和第二针，每个针具有远端并被安装成使得远端针可移动以接合缝合线的相应端部。缝合装置还包括致动器，其驱动针以接合缝合线。缝合装置还包括可操作地连接到细长主体的闭塞装置，使得闭塞装置可以从细长体的远端推进，以临时闭塞待缝合的切口。

4. 发明申请

US20110015655A1 Handle for Suturing Apparatus 有权
标题翻译：缝合器手柄
公开(公告)号：US20110015655A1
公开(公告)日：2011-01-20
申请号：US12890196
申请日：2010-09-24
申请人： Anthony A. Nobles , Steven E. Decker , Hung Tran , Benjamin G. Brosch
发明人： Anthony A. Nobles , Steven E. Decker , Hung Tran , Benjamin G. Brosch
IPC分类号： A61B17/062
CPC分类号： A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/0625 , A61B2017/00367 , A61B2017/00637 , A61B2017/00663 , A61B2017/00672 , A61B2017/0472 , A61B2017/2911 , A61B2017/2912
摘要： Methods and apparatus are provided for closing incisions within biological tissue. In one embodiment, a device and method are provided for suturing biological tissue, such as, for example, an organ or blood vessel. The suturing apparatus is particularly well suited for suturing an incision made in an artery, such as the femoral artery, following a catheterization procedure. The device eliminates the need to apply pressure to a patient's thigh for an extended period of time, and eliminates many of the complications and costs associated with the creation of a thrombus patch. In addition, the device comprises an improved handle portion which enables the physician to quickly and easily apply suture. The handle portion is very reliable and easy to manipulate. The suturing may be used in combination with existing catheter sheath introducers.
摘要翻译：提供了用于闭合生物组织内的切口的方法和装置。在一个实施例中，提供了用于缝合生物组织的装置和方法，例如器官或血管。缝合装置特别适用于在导管插入术后缝合在动脉（例如股动脉）上制成的切口。该装置不需要长时间地向患者的大腿施加压力，并且消除了与创建血栓贴片相关的许多并发症和成本。此外，该装置包括改进的手柄部分，其使医师能够快速且容易地应用缝线。手柄部分非常可靠，易于操作。缝合可以与现有的导管鞘引入器结合使用。

5. 发明授权

US06562052B2 Suturing device and method 有权
公开(公告)号：US06562052B2
公开(公告)日：2003-05-13
申请号：US09881550
申请日：2001-06-14
申请人： Anthony A. Nobles , Steven E. Decker , Benjamin G. Brosch
发明人： Anthony A. Nobles , Steven E. Decker , Benjamin G. Brosch
IPC分类号： A61B1704
CPC分类号： A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/0491 , A61B17/06166 , A61B17/0625 , A61B2017/00637 , A61B2017/00659 , A61B2017/00663 , A61B2017/00672 , A61B2017/00867 , A61B2017/0472 , A61B2017/06042 , A61B2017/2911
摘要： A suturing device and method allows a physician to remotely suture biological tissue. The device includes an elongate body, first and second arms operably connected to the elongated body, whereby each arm mounts an end portion of a suture, and first and second needles, each needle having a distal end and being mounted such that the distal end of the needle is movable to engage respective end portions of said suture. The suturing apparatus further includes an actuator which drives the needles to engage the suture non-simultaneously.

6. 发明申请

US20110190793A1 METHODS AND APPARATUSES FOR SUTURING OF CARDIAC OPENINGS 审中-公开
标题翻译：用于治疗心脏开放的方法和装置
公开(公告)号：US20110190793A1
公开(公告)日：2011-08-04
申请号：US13016897
申请日：2011-01-28
申请人： Anthony A. Nobles , Benjamin G. Brosch
发明人： Anthony A. Nobles , Benjamin G. Brosch
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B2017/00243 , A61B2017/047 , A61B2017/0472
摘要： A suturing apparatus configured to suture an opening extending through an outer wall of the heart, such as a transapical opening, can comprise an elongate body having a proximal end, a distal end, a tapered or rounded tip, one or more arms, and one or more needles. A handle at the proximal end of the elongate body can be configured to be manipulated from outside of the heart. The elongate body can have a substantially constant outer diameter between the handle and the distal end. The arms can hold portions of suture a distance away from the outer diameter of the elongate body. The arms can be extendable from said body from a retracted position to an extended position. The arms in the extended position can point distally and form an acute angle with a longitudinal axis of the elongate body. The plurality of needles can be movable to pass through heart tissue into engagement with the suture portions held by the arms and back through the heart tissue to draw the suture portions through the heart tissue.
摘要翻译：构造成缝合延伸穿过心脏外壁的开口（例如经脊开口）的缝合装置可以包括细长体，其具有近端，远端，锥形或圆形末端，一个或多个臂和一个或更多针。在细长体的近端处的手柄可构造成从心脏的外部被操纵。细长体可以在手柄和远端之间具有基本恒定的外径。臂可以将缝合部分与细长体的外径保持一定距离。臂可以从所述主体从缩回位置延伸到延伸位置。延伸位置的臂可以向远侧指向并与细长体的纵向轴线形成锐角。多个针可以是可移动的，以通过心脏组织与由手臂保持的缝线部分接合并穿过心脏组织，以将缝线部分穿过心脏组织。

7. 发明授权

US07803167B2 Handle for suturing apparatus 有权
标题翻译：手术用于缝合器械
公开(公告)号：US07803167B2
公开(公告)日：2010-09-28
申请号：US11235751
申请日：2005-09-27
申请人： Anthony A. Nobles , Steven E. Decker , Hung Tran , Benjamin G. Brosch
发明人： Anthony A. Nobles , Steven E. Decker , Hung Tran , Benjamin G. Brosch
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/0625 , A61B2017/00367 , A61B2017/00637 , A61B2017/00663 , A61B2017/00672 , A61B2017/0472 , A61B2017/2911 , A61B2017/2912
摘要： Methods and apparatus are provided for closing incisions within biological tissue. In one embodiment, a device and method are provided for suturing biological tissue, such as, for example, an organ or blood vessel. The suturing apparatus is particularly well suited for suturing an incision made in an artery, such as the femoral artery, following a catheterization procedure. The device eliminates the need to apply pressure to a patient's thigh for an extended period of time, and eliminates many of the complications and costs associated with the creation of a thrombus patch. In addition, the device comprises an improved handle portion which enables the physician to quickly and easily apply suture. The handle portion is very reliable and easy to manipulate. The suturing may be used in combination with existing catheter sheath introducers.
摘要翻译：提供了用于闭合生物组织内的切口的方法和装置。在一个实施例中，提供了用于缝合生物组织的装置和方法，例如器官或血管。缝合装置特别适用于在导管插入术后缝合在动脉（例如股动脉）上制成的切口。该装置不需要长时间地向患者的大腿施加压力，并且消除了与创建血栓贴片相关的许多并发症和成本。此外，该装置包括改进的手柄部分，其使医师能够快速且容易地应用缝线。手柄部分非常可靠，易于操作。缝合可以与现有的导管鞘引入器结合使用。

8. 发明授权

US07090686B2 Suturing device and method 有权
公开(公告)号：US07090686B2
公开(公告)日：2006-08-15
申请号：US10435928
申请日：2003-05-12
申请人： Anthony A. Nobles , Steven E. Decker , Benjamin G. Brosch
发明人： Anthony A. Nobles , Steven E. Decker , Benjamin G. Brosch
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/0491 , A61B17/06166 , A61B17/0625 , A61B2017/00637 , A61B2017/00659 , A61B2017/00663 , A61B2017/00672 , A61B2017/00867 , A61B2017/0472 , A61B2017/06042 , A61B2017/2911
摘要： A suturing device and method allows a physician to remotely suture biological tissue. The device includes an elongate body, first and second arms operably connected to the elongated body, whereby each arm mounts an end portion of a suture, and first and second needles, each needle having a distal end and being mounted such that the distal end of the needle is movable to engage respective end portions of said suture. The suturing apparatus further includes an actuator which drives the needles to engage the suture non-simultaneously.

9. 发明授权

US09649106B2 Suturing devices and methods for suturing an anatomic valve 有权
公开(公告)号：US09649106B2
公开(公告)日：2017-05-16
申请号：US14111534
申请日：2012-04-12
申请人： Anthony A. Nobles , Benjamin G. Brosch , William Ettlinger Cohn
发明人： Anthony A. Nobles , Benjamin G. Brosch , William Ettlinger Cohn
IPC分类号： A61B17/04 , A61B17/12 , A61B17/06 , A61B17/00
CPC分类号： A61B17/0483 , A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/06004 , A61B17/06066 , A61B2017/00243 , A61B2017/00575 , A61B2017/00663 , A61B2017/00783 , A61B2017/0406 , A61B2017/047 , A61B2017/0472 , A61B2017/0496 , A61B2017/06085 , A61B2017/061
摘要： Suturing apparatuses configured to suture biological tissue, such as an anatomical valve, can include an elongate member having a proximal end, a distal end, one or more arms, and one or more needles. A protective member may be used to inhibit contact between a distal end of a needle and surrounding tissue. Methods for suturing bodily tissue such as an anatomical valve may be performed with the suturing apparatuses. The suturing apparatuses may be used to suture adjacent valve leaflets or the base of a valve in order to treat or repair the valve.

10. 发明授权

US08496676B2 Handle for suturing apparatus 有权
标题翻译：手术用于缝合器械
公开(公告)号：US08496676B2
公开(公告)日：2013-07-30
申请号：US12890196
申请日：2010-09-24
申请人： Anthony A. Nobles , Steven E. Decker , Hung Tran , Benjamin G. Brosch
发明人： Anthony A. Nobles , Steven E. Decker , Hung Tran , Benjamin G. Brosch
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/0625 , A61B2017/00367 , A61B2017/00637 , A61B2017/00663 , A61B2017/00672 , A61B2017/0472 , A61B2017/2911 , A61B2017/2912
摘要： Methods and apparatus are provided for closing incisions within biological tissue. In one embodiment, a device and method are provided for suturing biological tissue, such as, for example, an organ or blood vessel. The suturing apparatus is particularly well suited for suturing an incision made in an artery, such as the femoral artery, following a catheterization procedure. The device eliminates the need to apply pressure to a patient's thigh for an extended period of time, and eliminates many of the complications and costs associated with the creation of a thrombus patch. In addition, the device comprises an improved handle portion which enables the physician to quickly and easily apply suture. The handle portion is very reliable and easy to manipulate. The suturing may be used in combination with existing catheter sheath introducers.
摘要翻译：提供了用于闭合生物组织内的切口的方法和装置。在一个实施例中，提供了用于缝合生物组织的装置和方法，例如器官或血管。缝合装置特别适用于在导管插入术后缝合在动脉（例如股动脉）上制成的切口。该装置不需要长时间地向患者的大腿施加压力，并且消除了与创建血栓贴片相关的许多并发症和成本。此外，该装置包括改进的手柄部分，其使医师能够快速且容易地应用缝线。手柄部分非常可靠，易于操作。缝合可以与现有的导管鞘引入器结合使用。

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