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1. 发明申请

US20100297635A1 COLLECTION AND MEASUREMENT OF EXHALED PARTICLES 有权
标题翻译：排出颗粒的收集和测量
公开(公告)号：US20100297635A1
公开(公告)日：2010-11-25
申请号：US12680428
申请日：2008-10-01
申请人： Anna-Carin Olin , Ann-Charlotte Almstrand , Jukka Lausmaa , Evert Ljungstrom
发明人： Anna-Carin Olin , Ann-Charlotte Almstrand , Jukka Lausmaa , Evert Ljungstrom
IPC分类号： C12Q1/68 , G01N30/96 , G01N33/53 , C12M1/34 , G01N33/92 , G01N33/20 , G01N33/00
CPC分类号： G01N15/0255 , A61B5/097 , A61B5/411 , G01N33/497 , G01N2015/0261
摘要： Particles are exhaled in the breath of animals. The nature and amounts of the particles can be indicative of certain medical conditions. They can therefore be collected, sorted according to size or mass and used in the diagnosis of one or more medical conditions. The invention provides a method and system for collecting and sorting exhaled particles and a method for diagnosis using said exhaled particles.
摘要翻译：颗粒呼吸在动物的呼吸中。颗粒的性质和量可以指示某些医疗状况。因此，它们可以根据大小或质量进行收集，并用于诊断一种或多种医疗条件。本发明提供了一种用于收集和分选呼出颗粒的方法和系统以及使用所述呼出颗粒进行诊断的方法。

2. 发明授权

US09976944B2 Collection and measurement of exhaled particles 有权
公开(公告)号：US09976944B2
公开(公告)日：2018-05-22
申请号：US12680428
申请日：2008-10-01
申请人： Anna-Carin Olin , Ann-Charlotte Almstrand , Jukka Lausmaa , Evert Ljungstrom
发明人： Anna-Carin Olin , Ann-Charlotte Almstrand , Jukka Lausmaa , Evert Ljungstrom
IPC分类号： A61B5/02 , G01N15/02 , A61B5/00 , A61B5/097 , G01N33/497
CPC分类号： G01N15/0255 , A61B5/097 , A61B5/411 , G01N33/497 , G01N2015/0261
摘要： Particles are exhaled in the breath of animals. The nature and amounts of the particles can be indicative of certain medical conditions. They can therefore be collected, sorted according to size or mass and used in the diagnosis of one or more medical conditions. The invention provides a method and system for collecting and sorting exhaled particles and a method for diagnosis using said exhaled particles.

3. 发明授权

US08349009B2 Implant, method for producing the implant, and use of the implant 有权
标题翻译：植入物，用于生产植入物的方法和植入物的使用
公开(公告)号：US08349009B2
公开(公告)日：2013-01-08
申请号：US12684591
申请日：2010-01-08
申请人： Jan Hall , Jukka Lausmaa
发明人： Jan Hall , Jukka Lausmaa
IPC分类号： A61F2/02 , A61C8/00
CPC分类号： A61F2/30767 , A61C8/0006 , A61C8/0012 , A61C8/0015 , A61F2/2803 , A61F2/3094 , A61F2002/30011 , A61F2002/30036 , A61F2002/3085 , A61F2002/30927 , A61F2250/0023 , A61F2250/0035 , A61F2310/00023 , A61F2310/00616 , A61F2310/00976 , A61L27/06 , A61L27/54 , A61L27/56 , A61L2300/414 , A61L2300/602
摘要： An implant that includes titanium and has one or more surfaces which can be applied in or on a bone growth area. One or more of the surfaces are arranged with a depot for bone-growth-initiating or bone-growth-stimulating substance, in which the depot is formed by a pore arrangement in a relatively thick oxide layer on the titanium. The substance is acted on, for a considerable period of time, by one or more release functions for the substance which permit a controlled or optimized release of substance to the surrounding tissue or bone growth area.
摘要翻译：一种植入体，其包括钛并且具有一个或多个可以施加在骨生长区域中或骨生长区域上的表面。一个或多个表面布置有用于骨生长起始或骨生长刺激物质的贮库，其中通过在钛上相对厚的氧化物层中的孔排列形成贮库。该物质在相当长的一段时间内通过物质的一种或多种释放功能起作用，所述功能允许将物质控制或优化地释放到周围组织或骨生长区域。

4. 发明授权

US08152856B2 Layer arranged on implant for bone or tissue structure, such an implant, and a method for application of the layer 有权
标题翻译：布置在用于骨或组织结构的植入物上的层，这种植入物，以及施加该层的方法
公开(公告)号：US08152856B2
公开(公告)日：2012-04-10
申请号：US12748867
申请日：2010-03-29
申请人： Jan Hall , Jukka Lausmaa
发明人： Jan Hall , Jukka Lausmaa
IPC分类号： A61F2/28
CPC分类号： A61C8/0012 , A61C8/0015 , A61L27/306 , A61L27/56
摘要： A layer is arranged on an implant for bone or tissue structure. The layer constitutes a boundary or barrier between the actual or unoxidized body of the implant and the structure for the purpose of increasing retention and has, in this context, a substantial thickness. The layer is designed with a channel network which gives the layer a substantial porosity. The channel network is designed with mouths which face towards the structure and whose respective cross-sectional diameters, at the surface of the layer facing towards the structure, are substantially less than the respective extents of the channels in and down into the layer as seen from the said surface.
摘要翻译：骨骼或组织结构的植入物上布置一层。该层构成植入物的实际或未氧化体与用于增加保留性的结构之间的边界或屏障，并且在本文中具有相当大的厚度。该层被设计成具有通道网络，其赋予层大的孔隙率。通道网络设计成具有面向结构的口，并且在层的面向结构的表面处的各自的横截面直径基本上小于从层中观察的通道的相应的范围所述表面。

5. 发明申请

US20100185293A1 LAYER ARRANGED ON IMPLANT FOR BONE OR TISSUE STRUCTURE, SUCH AN IMPLANT, AND A METHOD FOR APPLICATION OF THE LAYER 有权
标题翻译：用于骨或组织结构的植入物层，这样的植入物和施用层的方法
公开(公告)号：US20100185293A1
公开(公告)日：2010-07-22
申请号：US12748867
申请日：2010-03-29
申请人： Jan Hall , Jukka Lausmaa
发明人： Jan Hall , Jukka Lausmaa
IPC分类号： A61F2/02 , C25D11/08
CPC分类号： A61C8/0012 , A61C8/0015 , A61L27/306 , A61L27/56
摘要： A layer is arranged on an implant for bone or tissue structure. The layer constitutes a boundary or barrier between the actual or unoxidized body of the implant and the structure for the purpose of increasing retention and has, in this context, a substantial thickness. The layer is designed with a channel network which gives the layer a substantial porosity. The channel network is designed with mouths which face towards the structure and whose respective cross-sectional diameters, at the surface of the layer facing towards the structure, are substantially less than the respective extents of the channels in and down into the layer as seen from the said surface.
摘要翻译：骨骼或组织结构的植入物上布置一层。该层构成植入物的实际或未氧化体与用于增加保留性的结构之间的边界或屏障，并且在本文中具有相当大的厚度。该层被设计成具有通道网络，其赋予层大的孔隙率。通道网络设计成具有面向结构的口，并且在层的面向结构的表面处的各自的横截面直径基本上小于从层中观察的通道的相应的范围所述表面。

6. 发明授权

US07713307B1 Layer arranged on implant for bone or tissue structure 有权
标题翻译：层布置在植入物上用于骨或组织结构
公开(公告)号：US07713307B1
公开(公告)日：2010-05-11
申请号：US09980006
申请日：2000-05-23
申请人： Jan Hall , Jukka Lausmaa
发明人： Jan Hall , Jukka Lausmaa
IPC分类号： A61F2/28
CPC分类号： A61C8/0012 , A61C8/0015 , A61L27/306 , A61L27/56
摘要： A layer (2∝″) is arranged on an implant (1″) for bone or tissue structure (5). The layer constitutes a boundary or a barrier between the actual or unoxidized body of the implant (1″) and the structure for the purpose of increasing retention and has in this context, a substantial thickness (T′). The layer (2′″) is designed with a channel network (6) which gives the layer a substantial porosity. The channel network (6) is designed with mouths (3′,4′) which face towards the structure (5) and whose respective cross-sectional diameters (D), at the surface (2a′) of the layer (2′″) facing towards the structure (5), are substantially less than the respective extents (e.g., H) of the channels in and down into the layer (2′″) as seen from the said surface (2a′).
摘要翻译：在用于骨或组织结构（5）的植入物（1“）上布置有层（2α”）。该层构成植入物（1“）的实际或未氧化体与用于增加保留性的结构之间的边界或屏障，并且在本文中具有相当大的厚度（T'）。层（2“”）被设计成具有通道网络（6），其使层具有显着的孔隙率。通道网络（6）设计有朝向结构（5）的口（3'，4'），并且在层（2“）的表面（2a'）处具有各自的横截面直径（D））基本上小于从所述表面（2a'）看到的在层（2“”）内和向下的通道的相应范围（例如，H）。

7. 发明授权

US5697997A Method and device for preparing implant surfaces 失效
标题翻译：用于制备植入物表面的方法和装置
公开(公告)号：US5697997A
公开(公告)日：1997-12-16
申请号：US647284
申请日：1996-05-09
申请人： Bjorn-Owe Aronsson , Patrik Johansson , Bengt Kasemo , Jukka Lausmaa
发明人： Bjorn-Owe Aronsson , Patrik Johansson , Bengt Kasemo , Jukka Lausmaa
IPC分类号： A61C8/00 , A61F2/00 , A61F2/30 , A61L2/14 , A61L27/06 , A61L27/10 , B23K10/00 , C23C8/10 , C23C8/36 , C03B32/00
CPC分类号： A61L27/10 , A61F2/30767 , A61L2/14 , A61L27/06 , C23C8/10 , C23C8/36 , A61F2/3094 , A61F2310/00023 , A61F2310/00598 , Y10S623/901
摘要： A method for preparing implant surfaces using gas discharge plasma including conveying the implants to a vacuum chamber. The implants are treated with an inert gas plasma to remove existing surface contamination and oxide layers from the implant surfaces. The implants are treated with an oxidizing plasma or by means of thermal oxidation to reoxidizing the implant surfaces. The implant treatment steps are carried out in a closed space, including a controlled atmosphere and produce a highly accurate and reproducible microstructure, composition, purity, and sterility in the implants.
摘要翻译：一种使用气体放电等离子体制备植入物表面的方法，包括将植入物输送到真空室。用惰性气体等离子体处理植入物以从植入物表面去除现有的表面污染物和氧化物层。用氧化血浆或通过热氧化处理植入物以重新氧化植入物表面。植入物处理步骤在封闭空间中进行，包括受控气氛，并在植入物中产生高精度和可重复的微观结构，组成，纯度和无菌性。

8. 发明申请

US20120087954A1 ION SUBSTITUTED CALCIUM PHOSPHATE COATINGS 审中-公开
标题翻译：离子取代磷酸钙涂料
公开(公告)号：US20120087954A1
公开(公告)日：2012-04-12
申请号：US13266533
申请日：2010-04-26
申请人： Wei Xia , Carl Lindahl , Hakan Engqvist , Peter Thomsen , Jukka Lausmaa
发明人： Wei Xia , Carl Lindahl , Hakan Engqvist , Peter Thomsen , Jukka Lausmaa
IPC分类号： A61K33/42 , C23C16/44 , A61K9/00 , B05D3/10 , B05D3/02 , B05D5/00 , B05D3/06
CPC分类号： A61L27/32 , A61L2400/18
摘要： A method for the formation of a surface coating of an ion substituted calcium phosphate on a substrate, the coating itself and the use of the coating.
摘要翻译：在基材上形成离子取代的磷酸钙的表面涂层的方法，涂层本身和涂层的使用。

9. 发明授权

US07708558B1 Implant, method for producing the implant, and use of the implant 有权
标题翻译：植入物，用于生产植入物的方法和植入物的使用
公开(公告)号：US07708558B1
公开(公告)日：2010-05-04
申请号：US09980011
申请日：2000-05-23
申请人： Jan Hall , Jukka Lausmaa
发明人： Jan Hall , Jukka Lausmaa
IPC分类号： A61C8/00 , A61F2/28
CPC分类号： A61F2/30767 , A61C8/0006 , A61C8/0012 , A61C8/0015 , A61F2/2803 , A61F2/3094 , A61F2002/30011 , A61F2002/30036 , A61F2002/3085 , A61F2002/30927 , A61F2250/0023 , A61F2250/0035 , A61F2310/00023 , A61F2310/00616 , A61F2310/00976 , A61L27/06 , A61L27/54 , A61L27/56 , A61L2300/414 , A61L2300/602
摘要： An implant comprises or consists of titanium and has one or more surfaces which can be applied in or on a bone growth area. One or more of the said surfaces are arranged with a depot for bone-growth-initiating or bone-growth-stimulating substance, which depot is formed by a pore arrangement in a relatively thick oxide layer on the titanium. The substance is acted on, for a considerable period of time, by one or more release functions for the substance which permit a controlled or optimized release of substance to the surrounding tissue or bone growth area.
摘要翻译：植入物包含钛或由钛组成，并且具有一个或多个可以施加在骨生长区域中或骨生长区域上的表面。一个或多个所述表面布置有用于骨生长起始或骨生长刺激物质的贮库，所述贮存库通过在钛上相对厚的氧化物层中的孔布置形成。该物质在相当长的一段时间内通过物质的一种或多种释放功能起作用，所述功能允许将物质控制或优化地释放到周围组织或骨生长区域。

10. 发明申请

US20100112519A1 IMPLANT, METHOD FOR PRODUCING THE IMPLANT, AND USE OF THE IMPLANT 有权
标题翻译：植入物，植入物的制造方法和植入物的使用
公开(公告)号：US20100112519A1
公开(公告)日：2010-05-06
申请号：US12684591
申请日：2010-01-08
申请人： Jan Hall , Jukka Lausmaa
发明人： Jan Hall , Jukka Lausmaa
IPC分类号： A61C13/08
CPC分类号： A61F2/30767 , A61C8/0006 , A61C8/0012 , A61C8/0015 , A61F2/2803 , A61F2/3094 , A61F2002/30011 , A61F2002/30036 , A61F2002/3085 , A61F2002/30927 , A61F2250/0023 , A61F2250/0035 , A61F2310/00023 , A61F2310/00616 , A61F2310/00976 , A61L27/06 , A61L27/54 , A61L27/56 , A61L2300/414 , A61L2300/602
摘要： An implant comprises titanium and has one or more surfaces which can be applied in or on a bone growth area. One or more of the surfaces are arranged with a depot for bone-growth-initiating or bone-growth-stimulating substance, in which the depot is formed by a pore arrangement in a relatively thick oxide layer on the titanium. The substance is acted on, for a considerable period of time, by one or more release functions for the substance which permit a controlled or optimized release of substance to the surrounding tissue or bone growth area.
摘要翻译：植入物包括钛并且具有一个或多个可以施加在骨生长区域中或骨生长区域上的表面。一个或多个表面布置有用于骨生长起始或骨生长刺激物质的贮库，其中通过在钛上相对厚的氧化物层中的孔排列形成贮库。该物质在相当长的一段时间内通过物质的一种或多种释放功能起作用，所述功能允许将物质控制或优化地释放到周围组织或骨生长区域。

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