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1. 发明申请

US20050059606A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus 审中-公开
标题翻译：新型肽作为丙型肝炎病毒的NS3-丝氨酸蛋白酶抑制剂
公开(公告)号：US20050059606A1
公开(公告)日：2005-03-17
申请号：US10934141
申请日：2004-09-03
申请人： Anil Saksena , Viyyoor Girijavallabhan , Raymond Lovey , Edwin Jao , Ashok Arasappan , Tejal Parekh , Patrick Pinto , Frank Bennett , Jinping McCormick , Haiyan Wang , Russell Pike , Stephane Bogen , Yi-Tsung Liu , F. Njoroge , Ashit Ganguly , Terence Brunck , Scott Kemp , Odile Levy , Marguerita Lim-Wilby
发明人： Anil Saksena , Viyyoor Girijavallabhan , Raymond Lovey , Edwin Jao , Ashok Arasappan , Tejal Parekh , Patrick Pinto , Frank Bennett , Jinping McCormick , Haiyan Wang , Russell Pike , Stephane Bogen , Yi-Tsung Liu , F. Njoroge , Ashit Ganguly , Terence Brunck , Scott Kemp , Odile Levy , Marguerita Lim-Wilby
IPC分类号： C12N9/99 , A61K31/7052 , A61K38/00 , A61K38/21 , A61K38/55 , A61K45/00 , A61P1/16 , A61P31/12 , A61P31/14 , A61P35/00 , A61P43/00 , C07K7/00 , C07K7/02 , C07K7/06 , A61K38/08
CPC分类号： C07K7/06 , A61K38/00 , C07K7/02
摘要： The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such peptides as well as methods of using them to treat disorders associated with the HCV protease.
摘要翻译：本发明公开了具有HCV蛋白酶抑制活性的新型肽化合物及其制备方法。在另一个实施方案中，本发明公开了包含这些肽的药物组合物以及使用它们来治疗与HCV蛋白酶相关的病症的方法。

2. 发明申请

US20050176648A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus 有权
标题翻译：新型肽作为丙型肝炎病毒的NS3-丝氨酸蛋白酶抑制剂
公开(公告)号：US20050176648A1
公开(公告)日：2005-08-11
申请号：US11089192
申请日：2005-03-24
申请人： Anil Saksena , Viyyoor Girijavallabhan , Stephane Bogen , Raymond Lovey , Edwin Jao , Frank Bennett , Jinping McCormick , Haiyan Wang , Russell Pike , Yi-Tsung Liu , Tin-Yau Chan , Zhaoning Zhu , Ashok Arasappan , Kevin Chen , Srikanth Venkatraman , Tejal Parekh , Patrick Pinto , Bama Santhanam , F. Njoroge , Ashit Ganguly , Henry Vaccaro , Scott Kemp , Odile Levy , Marguerita Lim-Wilby , Susan Tamura
发明人： Anil Saksena , Viyyoor Girijavallabhan , Stephane Bogen , Raymond Lovey , Edwin Jao , Frank Bennett , Jinping McCormick , Haiyan Wang , Russell Pike , Yi-Tsung Liu , Tin-Yau Chan , Zhaoning Zhu , Ashok Arasappan , Kevin Chen , Srikanth Venkatraman , Tejal Parekh , Patrick Pinto , Bama Santhanam , F. Njoroge , Ashit Ganguly , Henry Vaccaro , Scott Kemp , Odile Levy , Marguerita Lim-Wilby , Susan Tamura
IPC分类号： C12N9/99 , A61K31/16 , A61K31/195 , A61K31/27 , A61K31/357 , A61K31/385 , A61K31/403 , A61K31/4164 , A61K31/445 , A61K31/7052 , A61K38/00 , A61K38/05 , A61K38/21 , A61K38/55 , A61K45/00 , A61P1/16 , A61P31/12 , A61P31/14 , A61P43/00 , C07C205/51 , C07C229/00 , C07D209/02 , C07K5/02 , C07K5/103 , C07K7/02 , C07K7/04 , C07K7/06 , A61K38/06 , A61K31/165 , A61K38/08
CPC分类号： C07K7/06 , A61K31/16 , A61K31/195 , A61K31/27 , A61K31/357 , A61K31/385 , A61K31/403 , A61K31/4164 , A61K31/445 , A61K38/05 , C07C205/51 , C07K5/101 , C07K7/02 , A61K2300/00
摘要： The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
摘要翻译：本发明公开了具有HCV蛋白酶抑制活性的新型肽化合物及其制备方法。在另一个实施方案中，本发明公开了包含这些化合物的药物组合物以及使用它们来治疗与HCV蛋白酶相关的病症的方法。

3. 发明申请

US20060205672A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus 审中-公开
公开(公告)号：US20060205672A1
公开(公告)日：2006-09-14
申请号：US11241656
申请日：2005-09-30
申请人： Anil Saksena , Viyyoor Girijavallabhan , Raymond Lovey , Edwin Jao , Frank Bennett , Jinping McCormick , Haiyan Wang , Russell Pike , Stephane Bogen , Tin-Yau Chan , Yi-Tsung Liu , Zhaoning Zhu , F. Njoroge , Ashok Arasappan , Tejal Parekh , Ashit Ganguly , Kevin Chen , Srikanth Venkatraman , Henry Vaccaro , Patrick Pinto , Bama Santhanam , Scott Kemp , Odile Levy , Marguerita Lim-Wilby , Susan Tamura , Wanli Wu , Siska Hendrata , Yuhua Huang
发明人： Anil Saksena , Viyyoor Girijavallabhan , Raymond Lovey , Edwin Jao , Frank Bennett , Jinping McCormick , Haiyan Wang , Russell Pike , Stephane Bogen , Tin-Yau Chan , Yi-Tsung Liu , Zhaoning Zhu , F. Njoroge , Ashok Arasappan , Tejal Parekh , Ashit Ganguly , Kevin Chen , Srikanth Venkatraman , Henry Vaccaro , Patrick Pinto , Bama Santhanam , Scott Kemp , Odile Levy , Marguerita Lim-Wilby , Susan Tamura , Wanli Wu , Siska Hendrata , Yuhua Huang
IPC分类号： A61K38/05 , C07K5/06
CPC分类号： C07K5/0202 , A61K38/00 , C07K5/0812 , C07K5/0827 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

4. 发明申请

US20070032433A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus 有权
标题翻译：新型肽作为丙型肝炎病毒的NS3-丝氨酸蛋白酶抑制剂
公开(公告)号：US20070032433A1
公开(公告)日：2007-02-08
申请号：US10052386
申请日：2002-01-18
申请人： Anil Saksena , Viyyoor Girijavallabhan , Raymond Lovey , Edwin Jao , Frank Bennett , Jinping Mc Cormick , Haiyan Wang , Russell Pike , Stephane Bogen , Tin-Yau Chan , Yi-Tsung Liu , Zhaoning Zhu , F. Njoroge , Ashok Arasappan , Tejal Parekh , Ashit Ganguly , Kevin Chen , Srikanth Venkatraman , Henry Vaccaro , Patrick Pinto , Bama Santhanam , Scott Kemp , Odile Levy , Marguerita Lim-wilby , Susan Tamura , Wanli Wu , Siska Hendrata , Yuhua Huang , Jesse Wong , Latha Nair
发明人： Anil Saksena , Viyyoor Girijavallabhan , Raymond Lovey , Edwin Jao , Frank Bennett , Jinping Mc Cormick , Haiyan Wang , Russell Pike , Stephane Bogen , Tin-Yau Chan , Yi-Tsung Liu , Zhaoning Zhu , F. Njoroge , Ashok Arasappan , Tejal Parekh , Ashit Ganguly , Kevin Chen , Srikanth Venkatraman , Henry Vaccaro , Patrick Pinto , Bama Santhanam , Scott Kemp , Odile Levy , Marguerita Lim-wilby , Susan Tamura , Wanli Wu , Siska Hendrata , Yuhua Huang , Jesse Wong , Latha Nair
IPC分类号： A61K38/06 , A61K38/04 , C07K17/00 , C07K16/00 , C07K7/00 , C07K5/00 , A61K38/00
CPC分类号： C07K5/0804 , A61K38/00 , C07K5/0202 , C07K5/0812 , C07K5/0827 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
摘要翻译：本发明公开了具有HCV蛋白酶抑制活性的新型化合物及其制备方法。在另一个实施方案中，本发明公开了包含这些化合物的药物组合物以及使用它们来治疗与HCV蛋白酶相关的病症的方法。

5. 发明授权

US06842804B2 System and method for converting radio control transmitter and joystick controller signals into universal serial bus signals 有权
标题翻译：将无线电控制发射机和操纵杆控制器信号转换为通用串行总线信号的系统和方法
公开(公告)号：US06842804B2
公开(公告)日：2005-01-11
申请号：US10354484
申请日：2003-01-30
申请人： Neal E. Cloud , Mark D. Williams , Scott Kemp
发明人： Neal E. Cloud , Mark D. Williams , Scott Kemp
IPC分类号： G06F3/00 , G06F3/038 , G06F13/38 , G09G5/00
CPC分类号： G06F3/038 , G06F3/002
摘要： A device for converting joystick controller generated analog and digital signals into Universal Serial Bus (USB) format, or for converting imported pulse position modulated (PPM) encoded signals from an external radio control (RC) transmitter into USB format data. The device is used, in an embodiment, for controlling simulated RC model aircraft as displayed, for example on a personal computer screen through the use of computer software. In an embodiment, the device includes a pair of two-axis gimbals, an auxiliary channel control potentiometer, and various control key switches to generate analog and digital joystick type signals as a result of direct manipulation by a user. The device also includes microcontroller circuitry for importing PPM signals, such as PPM signals generated by a commercially available model aircraft RC transmitter, to a USB port signal for interface with a computer.
摘要翻译：用于将操纵杆控制器转换成通用串行总线（USB）格式或将外部无线电控制（RC）发射机的进口脉冲位置调制（PPM）编码信号转换成USB格式数据）的装置。在一个实施例中，该装置用于通过使用计算机软件来控制例如在个人计算机屏幕上显示的模拟RC模型飞机。在一个实施例中，该装置包括一对双轴万向节，辅助通道控制电位器和各种控制键开关，以便由用户直接操纵的结果产生模拟和数字操纵杆式信号。该设备还包括用于将PPM信号（例如由市售的模型飞行器RC发射器产生的PPM信号）导入到与计算机接口的USB端口信号的微控制器电路。

6. 发明授权

US07010628B2 System and method for converting radio control transmitter and joystick controller signals into universal serial bus signals 有权
公开(公告)号：US07010628B2
公开(公告)日：2006-03-07
申请号：US10990850
申请日：2004-11-17
申请人： Neal E. Cloud , Mark D. Williams , Scott Kemp
发明人： Neal E. Cloud , Mark D. Williams , Scott Kemp
IPC分类号： G60F13/38
CPC分类号： G06F3/038 , G06F3/002
摘要： A device for converting joystick controller generated analog and digital signals into Universal Serial Bus (USB) format, or for converting imported pulse position modulated (PPM) encoded signals from an external radio control (RC) transmitter into USB format data. The device is used, in an embodiment, for controlling simulated RC model aircraft as displayed, for example on a personal computer screen through the use of computer software. In an embodiment, the device includes a pair of two-axis gimbals, an auxiliary channel control potentiometer, and various control key switches to generate analog and digital joystick type signals as a result of direct manipulation by a user. The device also includes microcontroller circuitry for importing PPM signals, such as PPM signals generated by a commercially available model aircraft RC transmitter, to a USB port signal for interface with a computer.

7. 发明申请

US20050091423A1 System and method for converting radio control transmitter and joystick controller signals into universal serial bus signals 有权
公开(公告)号：US20050091423A1
公开(公告)日：2005-04-28
申请号：US10990850
申请日：2004-11-17
申请人： Neal Cloud , Mark Williams , Scott Kemp
发明人： Neal Cloud , Mark Williams , Scott Kemp
IPC分类号： G06F3/00 , G06F3/038
CPC分类号： G06F3/038 , G06F3/002
摘要： A device for converting joystick controller generated analog and digital signals into Universal Serial Bus (USB) format, or for converting imported pulse position modulated (PPM) encoded signals from an external radio control (RC) transmitter into USB format data. The device is used, in an embodiment, for controlling simulated RC model aircraft as displayed, for example on a personal computer screen through the use of computer software. In an embodiment, the device includes a pair of two-axis gimbals, an auxiliary channel control potentiometer, and various control key switches to generate analog and digital joystick type signals as a result of direct manipulation by a user. The device also includes microcontroller circuitry for importing PPM signals, such as PPM signals generated by a commercially available model aircraft RC transmitter, to a USB port signal for interface with a computer.

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