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    • 1. 发明申请
    • Tubular patent foramen ovale (PFO) closure device with catch system
    • 管状卵圆孔(PFO)闭合装置带捕获系统
    • US20070010851A1
    • 2007-01-11
    • US11395718
    • 2006-03-31
    • Andrzej ChanduszkoDavid Callaghan
    • Andrzej ChanduszkoDavid Callaghan
    • A61B17/08
    • A61B17/0057A61B2017/00575A61B2017/00592A61B2017/00606A61B2017/00619A61B2017/00623
    • The present invention provides a device for occluding an anatomical aperture, such as an atrial septal defect (ASD) or a patent foramen ovale (PFO). The occluder includes two sides connected by a central tube. The occluder is formed from a tube, which is cut to produce struts in each side. Upon the application of force, the struts deform into loops. The loops may be of various shapes, sizes, and configurations, and, in at least some embodiments, the loops have rounded peripheries. In some embodiments, at least one of the sides includes a tissue scaffold. The occluder further includes a catch system that maintains its deployed state in vivo. When the occluder is deployed in vivo, the two sides are disposed on opposite sides of the septal tissue surrounding the aperture and the catch system is deployed so that the occluder exerts a compressive force on the septal tissue and closes the aperture.
    • 本发明提供一种用于闭塞解剖孔的装置,例如房间隔缺损(ASD)或卵圆孔卵孔(PFO)。 封堵器包括通过中心管连接的两侧。 封堵器由管子形成,其被切割以在每一侧产生支柱。 施加力时,支柱变形成环。 环可以是各种形状,尺寸和构造,并且在至少一些实施例中,环具有圆形的周边。 在一些实施例中,至少一个侧面包括组织支架。 闭塞器还包括在体内维持其部署状态的捕获系统。 当闭塞器部署在体内时,两侧设置在围绕孔的间隔组织的相对侧上,并且捕获系统被展开,使得封堵器对隔膜组织施加压缩力并闭合孔。
    • 4. 发明授权
    • Sterilization device and method
    • 灭菌装置及方法
    • US08231619B2
    • 2012-07-31
    • US12692057
    • 2010-01-22
    • David CallaghanMatthew LaPlacaJeffrey ModelMark PutnamJames Duronio
    • David CallaghanMatthew LaPlacaJeffrey ModelMark PutnamJames Duronio
    • A61B18/12
    • A61F6/225A61B17/12022A61B17/12031A61B17/12159A61B18/1206A61B18/1492A61B2017/00898A61B2017/1205A61B2018/00083A61B2018/00196A61B2018/00875
    • Sterilization devices and methods for deploying porous implants within the fallopian tubes are disclosed. The devices include a catheter component including an external electrode sheath containing at least two deployable implants and a positioning member. Sliding the external sheath proximally disposes the implants within the fallopian tubes, while sliding both the positioning member and external electrode sheath distally reloads a second implant into the external electrode sheath. The devices further includes a handle component, which houses a chassis, external electrode sheath carrier, reciprocating shaft, positioning member carrier and first and second engaging members. The reciprocating shaft may be operated by a motor to slide distally and proximally along a long axis. The reciprocating shaft, external electrode sheath and its carrier, upon selective actuation, move together proportionally to deploy and reload the implants to facilitate occlusion of the fallopian tubes and complete sterilization.
    • 公开了用于在输卵管内部署多孔植入物的灭菌装置和方法。 所述装置包括导管部件,该导管部件包括包含至少两个可展开植入物的外部电极护套和定位部件。 将外部护套向近侧滑动,将植入物放置在输卵管内,同时使定位构件和外部电极护套两侧滑动将第二植入物再次加载到外部电极护套中。 这些装置还包括手柄部件,其容纳底盘,外部电极护套托架,往复运动轴,定位构件托架以及第一和第二接合构件。 往复轴可以由马达操作,以沿长轴向远侧和近侧滑动。 往复运动轴,外部电极护套及其载体在选择性致动时,按比例移动,以部署和重新装载植入物,以便于输卵管的闭塞和完全消毒。
    • 6. 发明申请
    • Atraumatic ball tip and side wall opening
    • 无创球头和侧壁开口
    • US20090036840A1
    • 2009-02-05
    • US12232842
    • 2008-09-25
    • Victor E. VirayDavid Callaghan
    • Victor E. VirayDavid Callaghan
    • A61M25/00
    • A61F6/225A61M25/0136A61M37/0069
    • A delivery catheter with a plug ejection mechanism with a fluid filled actuator incorporated in the catheter handle is disclosed. After delivery of RF energy, the plug is deployed within the region of the lesion by activating the plug ejection mechanism. A delivery catheter used for female sterilization with an atraumatic ball tip and an opening in the side wall of the catheter body is disclosed. The delivery catheter includes a hinge that will yield or bend under a certain load to prevent injury to the uterine wall or fallopian tube. The side wall opening is angled to allow proper placement of a plug into the fallopian tube for occlusion of the fallopian tube.
    • 公开了一种具有塞子排出机构的输送导管,其具有结合在导管手柄中的流体填充致动器。 在RF能量传递之后,通过启动插头弹出机构将插头部署在病变区域内。 公开了一种用于与无创伤球头和导管主体侧壁中的开口进行雌性灭菌的输送导管。 输送导管包括在一定负荷下产生或弯曲的铰链,以防止对子宫壁或输卵管的损伤。 侧壁开口成角度以允许将插塞适当地放置到输卵管中以阻塞输卵管。
    • 7. 发明申请
    • Deformable flap catch mechanism for occluder device
    • 闭塞装置可变形襟翼捕捉机构
    • US20070244517A1
    • 2007-10-18
    • US11729637
    • 2007-03-29
    • David Callaghan
    • David Callaghan
    • A61B17/08
    • A61B17/0057A61B2017/00575A61B2017/00592A61B2017/00606A61B2017/00619A61B2017/00623A61B2017/00862
    • Devices, delivery systems, and delivery techniques for an occlusion device for closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. Specifically, an occluder with a catch member that holds the occluder in the deployed, expanded profile configuration is provided within a delivery sheath. The proximal end of the catch member includes a flap that when positioned proximal to the proximal end of the occluder holds the occluder in the expanded profile configuration. The flap is sized and formed of a material that allows the flap to deform by bending back and forth in axial and radial directions. In certain embodiments, the flap has segments divided by notches. In certain embodiments, deforming the flap in the proximal direction requires a different amount of force than deforming the flap in the distal direction.
    • 描述了用于闭合物理异常的闭塞装置的装置,输送系统和输送技术,例如房间隔缺损,卵圆孔专利(PFO)以及其他间隔和血管缺陷。 具体而言,在输送护套内设置有具有将封堵器保持在展开的扩张型材构造中的捕捉构件的封堵器。 捕获构件的近端包括翼片,当定位在封闭器的近端附近时,将封堵器保持在膨胀的轮廓构造中。 该襟翼的尺寸和形状由允许襟翼通过在轴向和径向方向来回弯曲而变形的材料形成。 在某些实施例中,翼片具有由切口划分的段。 在某些实施例中,使翼片沿近端方向变形需要与翼片在远侧方向上的变形不同的力量。
    • 10. 发明申请
    • Sterilization Device and Method
    • 灭菌装置及方法
    • US20110180073A1
    • 2011-07-28
    • US12692057
    • 2010-01-22
    • David CallaghanMatthew LaPlacaJeffrey ModelMark PutnamJames Duronio
    • David CallaghanMatthew LaPlacaJeffrey ModelMark PutnamJames Duronio
    • A61B18/14A61F6/22
    • A61F6/225A61B17/12022A61B17/12031A61B17/12159A61B18/1206A61B18/1492A61B2017/00898A61B2017/1205A61B2018/00083A61B2018/00196A61B2018/00875
    • Sterilization devices and methods for deploying porous implants within the fallopian tubes are disclosed. The devices include a catheter component including an external electrode sheath containing at least two deployable implants and a positioning member. Sliding the external sheath proximally disposes the implants within the fallopian tubes, while sliding both the positioning member and external electrode sheath distally reloads a second implant into the external electrode sheath. The devices further includes a handle component, which houses a chassis, external electrode sheath carrier, reciprocating shaft, positioning member carrier and first and second engaging members. The reciprocating shaft may be operated by a motor to slide distally and proximally along a long axis. The reciprocating shaft, external electrode sheath and its carrier, upon selective actuation, move together proportionally to deploy and reload the implants to facilitate occlusion of the fallopian tubes and complete sterilization.
    • 公开了用于在输卵管内部署多孔植入物的灭菌装置和方法。 所述装置包括导管部件,该导管部件包括包含至少两个可展开植入物的外部电极护套和定位部件。 将外部护套向近侧滑动,将植入物放置在输卵管内,同时使定位构件和外部电极护套两侧滑动将第二植入物再次加载到外部电极护套中。 这些装置还包括手柄部件,其容纳底盘,外部电极护套托架,往复运动轴,定位构件托架以及第一和第二接合构件。 往复轴可以由马达操作,以沿长轴向远侧和近侧滑动。 往复运动轴,外部电极护套及其载体在选择性致动时,按比例移动,以部署和重新装载植入物,以便于输卵管的闭塞和完全消毒。