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1. 发明授权

US08167933B2 Annuloplasty apparatus and methods 失效
标题翻译：瓣膜成形术装置及方法
公开(公告)号：US08167933B2
公开(公告)日：2012-05-01
申请号：US12880823
申请日：2010-09-13
申请人： Andrew Lee , Norman Fung , John D. Nguyen , Nga T. Doan , Laurent Schaller
发明人： Andrew Lee , Norman Fung , John D. Nguyen , Nga T. Doan , Laurent Schaller
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61F2/2442
摘要： An annuloplasty system for repairing a valve in a patient's heart comprises a surgical implant including a member having first and second end portions. The implant member further is configured and/or adapted to form a partial ring along a portion of one of the valve annulae of a patient's heart such as the mitral or tricuspid valve annulus. The implant member is axially elastic such that it can axially expand and contract and includes first and second anchors extending from the end portions of the implant member. The anchors are adapted to anchor the implant in tissue such as the mitral or tricuspid valve annulus. The system can facilitate tissue plication (e.g., of the posterior annulus of the mitral valve or the annulus of the tricuspid valve) and reinforcement of a valve annulus.
摘要翻译：用于修复患者心脏中的瓣膜的瓣环成形术系统包括外科植入物，其包括具有第一和第二端部的构件。植入物构件还被构造和/或适于沿着患者心脏的瓣膜瓣的一部分形成部分环，例如二尖瓣或三尖瓣瓣环。植入物构件具有轴向弹性，使得其可以轴向膨胀和收缩，并且包括从植入构件的端部延伸的第一和第二锚定件。锚固件适于将植入物锚定在诸如二尖瓣或三尖瓣瓣环的组织中。该系统可以促进组织塌陷（例如，二尖瓣的后部环或三尖瓣的环）并加强瓣膜环。

2. 发明申请

US20110004298A1 ANNULOPLASTY APPARATUS AND METHODS 失效
标题翻译： ANNULOPLASTY装置和方法
公开(公告)号：US20110004298A1
公开(公告)日：2011-01-06
申请号：US12880823
申请日：2010-09-13
申请人： Andrew Lee , Norman Fung , John D. Nguyen , Nga T. Doan , Laurent Schaller
发明人： Andrew Lee , Norman Fung , John D. Nguyen , Nga T. Doan , Laurent Schaller
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61F2/2442
摘要： An annuloplasty system for repairing a valve in a patient's heart comprises a surgical implant including a member having first and second end portions. The implant member further is configured and/or adapted to form a partial ring along a portion of one of the valve annulae of a patient's heart such as the mitral or tricuspid valve annulus. The implant member is axially elastic such that it can axially expand and contract and includes first and second anchors extending from the end portions of the implant member. The anchors are adapted to anchor the implant in tissue such as the mitral or tricuspid valve annulus. The system can facilitate tissue plication (e.g., of the posterior annulus of the mitral valve or the annulus of the tricuspid valve) and reinforcement of a valve annulus.
摘要翻译：用于修复患者心脏中的瓣膜的瓣环成形术系统包括外科植入物，其包括具有第一和第二端部的构件。植入物构件还被构造和/或适于沿着患者心脏的瓣膜瓣的一部分形成部分环，例如二尖瓣或三尖瓣瓣环。植入物构件具有轴向弹性，使得其可以轴向膨胀和收缩，并且包括从植入构件的端部延伸的第一和第二锚定件。锚固件适于将植入物锚定在诸如二尖瓣或三尖瓣瓣环的组织中。该系统可以促进组织塌陷（例如，二尖瓣的后部环或三尖瓣的环）并加强瓣膜环。

3. 发明申请

US20110126395A1 Multiple Bias Surgical Fastener 失效
标题翻译：多重偏心手术紧固件
公开(公告)号：US20110126395A1
公开(公告)日：2011-06-02
申请号：US13022207
申请日：2011-02-07
申请人： John Nguyen , Nga T. Doan , Laurent Schaller
发明人： John Nguyen , Nga T. Doan , Laurent Schaller
IPC分类号： B23P11/00
CPC分类号： A61B17/06 , A61B17/06004 , A61B17/064 , A61B17/068 , A61B17/11 , A61B2017/06009 , A61B2017/06057 , A61B2017/06171 , A61B2017/0647 , A61B2017/1135 , Y10T29/49826 , Y10T29/49865
摘要： A surgical fastener comprising a clip movable between an open configuration and a closed configuration and a biasing member contacting the clip and biasing the dip to its open configuration when the biasing member is actuated. The biasing member and clip both tend to assume the closed configuration when no external forces are applied to them. A needle may be releasably attached to the clip. Methods for making the fasteners are also disclosed, in which both the clip and the biasing member are set in the closed position.
摘要翻译：一种手术紧固件，其包括可在打开构型和闭合构型之间移动的夹子，以及当所述偏置构件被致动时，所述偏置构件接触所述夹子并将所述倾斜偏压到其打开构型。当没有外力施加到偏压构件和夹子时，偏压构件和夹子都倾向于呈现闭合构型。针可以可释放地附接到夹子。还公开了制造紧固件的方法，其中夹子和偏置构件都被设置在关闭位置。

4. 发明授权

US06551332B1 Multiple bias surgical fastener 有权
标题翻译：多重偏倚手术紧固件
公开(公告)号：US06551332B1
公开(公告)日：2003-04-22
申请号：US09541397
申请日：2000-03-31
申请人： John Nguyen , Nga T. Doan , Laurent Schaller
发明人： John Nguyen , Nga T. Doan , Laurent Schaller
IPC分类号： A61B1708
CPC分类号： A61B17/06 , A61B17/06004 , A61B17/064 , A61B17/068 , A61B17/11 , A61B2017/06009 , A61B2017/06057 , A61B2017/06171 , A61B2017/0647 , A61B2017/1135 , Y10T29/49826 , Y10T29/49865
摘要： A surgical fastener comprising a clip movable between an open configuration and a closed configuration and a biasing member contacting the clip and biasing the clip to its open configuration when the biasing member is actuated. The biasing member and clip both tend to assume the closed configuration when no external forces are applied to them. A needle may be releasably attached to the clip. Methods for making the fasteners are also disclosed, in which both the clip and the biasing member are set in the closed position.
摘要翻译：一种手术紧固件，包括可在打开构型和闭合构型之间移动的夹子，以及偏置构件，当偏置构件被致动时，偏压构件与夹子接触并将夹子偏压到其打开构型。当没有外力施加到偏压构件和夹子时，偏压构件和夹子都倾向于呈现闭合构型。针可以可释放地附接到夹子。还公开了制造紧固件的方法，其中夹子和偏置构件都被设置在关闭位置。

5. 发明授权

US08353092B2 Multiple bias surgical fastener 失效
标题翻译：多重偏倚手术紧固件
公开(公告)号：US08353092B2
公开(公告)日：2013-01-15
申请号：US13022207
申请日：2011-02-07
申请人： John Nguyen , Nga T. Doan , Laurent Schaller
发明人： John Nguyen , Nga T. Doan , Laurent Schaller
IPC分类号： B21F1/00
CPC分类号： A61B17/06 , A61B17/06004 , A61B17/064 , A61B17/068 , A61B17/11 , A61B2017/06009 , A61B2017/06057 , A61B2017/06171 , A61B2017/0647 , A61B2017/1135 , Y10T29/49826 , Y10T29/49865
摘要： A surgical fastener comprising a clip movable between an open configuration and a closed configuration and a biasing member contacting the clip and biasing the dip to its open configuration when the biasing member is actuated. The biasing member and clip both tend to assume the closed configuration when no external forces are applied to them. A needle may be releasably attached to the clip. Methods for making the fasteners are also disclosed, in which both the clip and the biasing member are set in the closed position.
摘要翻译：一种手术紧固件，其包括可在打开构型和闭合构型之间移动的夹子，以及当所述偏置构件被致动时，所述偏置构件接触所述夹子并将所述倾斜偏压到其打开构型。当没有外力施加到偏压构件和夹子时，偏压构件和夹子都倾向于呈现闭合构型。针可以可释放地附接到夹子。还公开了制造紧固件的方法，其中夹子和偏置构件都被设置在关闭位置。

6. 发明授权

US07896892B2 Multiple bias surgical fastener 有权
标题翻译：多重偏倚手术紧固件
公开(公告)号：US07896892B2
公开(公告)日：2011-03-01
申请号：US10408019
申请日：2003-04-03
申请人： John Nguyen , Nga T. Doan , Laurent Schaller
发明人： John Nguyen , Nga T. Doan , Laurent Schaller
IPC分类号： A61B17/08
CPC分类号： A61B17/06 , A61B17/06004 , A61B17/064 , A61B17/068 , A61B17/11 , A61B2017/06009 , A61B2017/06057 , A61B2017/06171 , A61B2017/0647 , A61B2017/1135 , Y10T29/49826 , Y10T29/49865
摘要： A surgical fastener comprising a clip movable between an open configuration and a closed configuration and a biasing member contacting the clip and biasing the clip to its open configuration when the biasing member is actuated. The biasing member and clip both tend to assume the closed configuration when no external forces are applied to them. A needle may be releasably attached to the clip. Methods for making the fasteners are also disclosed, in which both the clip and the biasing member are set in the closed position.
摘要翻译：一种手术紧固件，包括可在打开构型和闭合构型之间移动的夹子，以及偏置构件，当偏置构件被致动时，偏压构件与夹子接触并将夹子偏压到其打开构型。当没有外力施加到偏压构件和夹子时，偏压构件和夹子都倾向于呈现闭合构型。针可以可释放地附接到夹子。还公开了制造紧固件的方法，其中夹子和偏置构件都被设置在关闭位置。

7. 发明授权

US06063104A Detachable, varying flexibility, aneurysm neck bridge 有权
标题翻译：可分离，灵活性差，动脉瘤颈桥
公开(公告)号：US06063104A
公开(公告)日：2000-05-16
申请号：US313958
申请日：1999-05-18
申请人： Francisco S. Villar , Nestor Aganon , Nga T. Doan , Robert M. Abrams , Clifford Teoh
发明人： Francisco S. Villar , Nestor Aganon , Nga T. Doan , Robert M. Abrams , Clifford Teoh
IPC分类号： A61B17/03 , A61B17/12
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12172 , A61B2017/12063
摘要： This is a device for bridging the neck of either a wide-necked or narrow-necked aneurysm as may be found in the vasculature. It may be used to stabilize the placement of vaso-occlusive devices such as helically wound coils in the aneurysm or may be used to, at least partially, close the aneurysm neck. The vaso-occlusive devices, commonly helically wound coils, are delivered by a core wire which is linked to the coils by an electrolytically severable joint. The core wire will often be insulated. The retainer assembly itself is also attached to another delivery device, such as a core wire, and desirably is severed from the core or delivery wire by the use of another electrolytically severable joint. The inventive neck bridge typically has a number of array elements which are intended to be resident within the aneurysm after the device is deployed from the distal end of a catheter. Central to this invention is the use of array elements having differing flexibility or constituent members of the array elements, e.g., wires making up the array elements, which are of differing flexibilities. After deployment of this retainer, the aneurysm may be at least partially filled with vaso-occlusive devices such as helically wound coils.
摘要翻译：这是用于桥接可能在脉管系统中发现的宽颈或窄颈动脉瘤的颈部的装置。其可以用于稳定血管闭塞装置的放置，例如螺旋缠绕的线圈在动脉瘤中，或者可以用于至少部分地闭合动脉瘤颈部。通常为螺旋缠绕线圈的血管收缩装置由通过电解分离的关节连接到线圈的芯线递送。芯线通常是绝缘的。保持器组件本身也附接到另一个输送装置，例如芯线，并且期望地通过使用另一个可电解的接头与芯或输送线断开。本发明的颈桥通常具有许多阵列元件，其在从导管的远端部署装置之后意图驻留在动脉瘤内。本发明的中心是使用具有不同柔性的阵列元件或阵列元件的构成元件，例如构成阵列元件的线，其具有不同的灵活性。在部署该保持器之后，动脉瘤可以至少部分地被血管闭塞装置填充，例如螺旋卷绕的线圈。

8. 发明授权

US5935148A Detachable, varying flexibility, aneurysm neck bridge 失效
公开(公告)号：US5935148A
公开(公告)日：1999-08-10
申请号：US103472
申请日：1998-06-24
申请人： Francisco S. Villar , Nestor Aganon , Nga T. Doan , Robert M. Abrams , Clifford Teoh
发明人： Francisco S. Villar , Nestor Aganon , Nga T. Doan , Robert M. Abrams , Clifford Teoh
IPC分类号： A61B17/03 , A61B17/12
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12172 , A61B2017/12063
摘要： This is a device for bridging the neck of either a wide-necked or narrow-necked aneurysm as may be found in the vasculature. It may be used to stabilize the placement of vaso-occlusive devices such as helically wound coils in the aneurysm or may be used to, at least partially, close the aneurysm neck. The vaso-occlusive devices, commonly helically wound coils, are delivered by a core wire which is linked to the coils by an electrolytically severable joint. The core wire will often be insulated. The retainer assembly itself is also attached to another delivery device, such as a core wire, and desirably is severed from the core or delivery wire by the use of another electrolytically severable joint. The inventive neck bridge typically has a number of array elements which are intended to be resident within the aneurysm after the device is deployed from the distal end of a catheter. Central to this invention is the use of array elements having differing flexibility or constituent members of the array elements, e.g., wires making up the array elements, which are of differing flexibilities. After deployment of this retainer, the aneurysm may be at least partially filled with vaso-occlusive devices such as helically wound coils.

9. 发明授权

US06960221B2 Tissue connector apparatus with cable release 失效
标题翻译：具有电缆释放的组织连接器设备
公开(公告)号：US06960221B2
公开(公告)日：2005-11-01
申请号：US10188013
申请日：2002-07-01
申请人： Liem Ho , Isidro Matias Gandionco , Nga T. Doan
发明人： Liem Ho , Isidro Matias Gandionco , Nga T. Doan
IPC分类号： A61B17/00 , A61B17/06 , A61B17/08 , A61B17/11 , A61F2/00
CPC分类号： A61B17/083 , A61B17/06 , A61B17/06004 , A61B2017/00867 , A61B2017/06057 , A61B2017/06076 , A61B2017/1135 , A61F2002/30093 , A61F2210/0019
摘要： A tissue connector assembly comprising a clip movable between an open configuration and a closed configuration and a mechanical restraining device including a plurality of strands releasably attachable to the clip for restraining the clip in its open configuration. A needle may be releasably attached to the clip. A flexible member may also interconnect the clip and the needle.
摘要翻译：一种组织连接器组件，其包括可在打开构型和闭合构型之间移动的夹子，以及机械约束装置，其包括可释放地附接到夹子的多个股线，用于将夹子限制在其打开构型。针可以可释放地附接到夹子。柔性构件还可以使夹子和针相互连接。

10. 发明授权

US06514265B2 Tissue connector apparatus with cable release 有权
标题翻译：具有电缆释放的组织连接器设备
公开(公告)号：US06514265B2
公开(公告)日：2003-02-04
申请号：US09259705
申请日：1999-03-01
申请人： Liem Ho , Isidro Matias Gandionco , Nga T. Doan
发明人： Liem Ho , Isidro Matias Gandionco , Nga T. Doan
IPC分类号： A61B1708
CPC分类号： A61B17/083 , A61B17/06 , A61B17/06004 , A61B2017/00867 , A61B2017/06057 , A61B2017/06076 , A61B2017/1135 , A61F2002/30093 , A61F2210/0019
摘要： A tissue connector assembly comprising a clip movable between an open configuration and a closed configuration and a mechanical restraining device including a plurality of strands releasably attachable to the clip for restraining the clip in its open configuration. A needle may be releasably attached to the clip. A flexible member may also interconnect the clip and the needle.
摘要翻译：一种组织连接器组件，其包括可在打开构型和闭合构型之间移动的夹子，以及机械约束装置，其包括可释放地附接到夹子的多个股线，用于将夹子限制在其打开构型。针可以可释放地附接到夹子。柔性构件还可以使夹子和针相互连接。

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