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1. 发明申请

US20100298871A1 SELF-RETAINING WOUND CLOSURE DEVICE INCLUDING AN ANCHORING LOOP 审中-公开
标题翻译：自锁闭合装置，包括一个锚定环
公开(公告)号：US20100298871A1
公开(公告)日：2010-11-25
申请号：US12849956
申请日：2010-08-04
申请人： Gregory L. Ruff , Jeffrey C. Leung , Andrew Kaplan , Matthew A. Megaro , Stanton D. Batchelor
发明人： Gregory L. Ruff , Jeffrey C. Leung , Andrew Kaplan , Matthew A. Megaro , Stanton D. Batchelor
IPC分类号： A61L17/12 , A61B17/04 , A61B17/06
CPC分类号： A61B17/06166 , A61B17/04 , A61B17/0401 , A61B17/06 , A61B17/064 , A61B17/11 , A61B17/1146 , A61B2017/00761 , A61B2017/0412 , A61B2017/0417 , A61B2017/0462 , A61B2017/0464 , A61B2017/06057 , A61B2017/06171 , A61B2017/06176
摘要： A self-retaining suture includes a plurality of tissue retainers which allow deployment in a deployment direction, but prevent movement in the opposite direction. The self-retaining suture has a needle at the proximal end and a tissue anchor at the distal end. The tissue anchor includes a curved portion of the suture formed into a loop which anchors the suture in the tissue. Additionally, the suture can be passed through a tissue and then passed through the loop to secure the distal end of the suture to the tissue.
摘要翻译：自固定缝合线包括允许在展开方向上展开但防止沿相反方向移动的多个组织保持器。自固位缝合线在近端具有针，在远端具有组织锚。组织锚固件包括缝合线的弯曲部分，其形成为将缝合线锚定在组织中的环。另外，缝合线可以穿过组织，然后穿过环，以将缝合线的远端固定到组织。

2. 发明授权

US10548592B2 Suture methods and devices 有权
公开(公告)号：US10548592B2
公开(公告)日：2020-02-04
申请号：US10908539
申请日：2005-05-16
申请人： Gregory L. Ruff , Jeffrey C. Leung , Andrew Kaplan , Matthew A. Megaro , Stanton D. Batchelor
发明人： Gregory L. Ruff , Jeffrey C. Leung , Andrew Kaplan , Matthew A. Megaro , Stanton D. Batchelor
IPC分类号： A61B17/06 , A61B17/04 , A61B17/064 , A61B17/11 , A61B17/00
摘要： A barbed suture including a body with barbs on the periphery, a pointed end, and an anchor at one end to resist movement of the suture in the direction of the pointed end is provided. One or more limbs on the anchor may be provided, which may be arcuate, of varying lengths, and of varying distribution about the periphery of the suture body. Other anchor designs are provided. Methods of placing single-directional and bi-directional barbed sutures to approximate the tissue on each side of a wound and to position and support tissue in the absence of a wound, as in cosmetic surgery, are provided, and may include terminal J-stitches or S-stitches. Methods of placement may be made with sharp, pointed ends, which may be needles, or insertion devices. Sinusoidal patterns of sutures that have amplitudes generally perpendicular to the resultant holding force of the suture are provided.

3. 发明授权

US07056331B2 Suture method 有权
公开(公告)号：US07056331B2
公开(公告)日：2006-06-06
申请号：US10065256
申请日：2002-09-30
申请人： Andrew Kaplan , Gregory L. Ruff , Jeffrey C. Leung , Matthew A. Megaro
发明人： Andrew Kaplan , Gregory L. Ruff , Jeffrey C. Leung , Matthew A. Megaro
IPC分类号： A61B17/04
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/04 , A61B17/06061 , A61B17/06166 , A61B17/062 , A61B17/1114 , A61B17/1146 , A61B2017/00575 , A61B2017/0061 , A61B2017/00632 , A61B2017/00663 , A61B2017/00792 , A61B2017/06052 , A61B2017/06057 , A61B2017/06171 , A61B2017/06176 , A61B2017/1135
摘要： A method for joining and holding closed a wound in bodily tissue, fastening junctions of wounds, tying off wounds, joining a foreign element to tissue, and altering the position of tissue using a barbed suture including sharp pointed ends. Each end of the suture includes barbs on that permit movement in an opposing direction to the barbs on the other end of the suture. This two-way barbed suture is used by the method of the present invention in applications including abdominal surgeries such as a Nissen fundoplication, laparoscopic uses such as stabilizing a bowel structure and performing a closure of a cystostomy, liver to bowel anastomosis, closure of an orifice of a Zenker's Diverticulum, endoscopic uses such as closure of ulcerative lesions or and post-procedural tissue defects, bladder wound closure, valve replacement surgery, device attachment, cosmetic surgery, and blood vessel wound closure.

4. 发明授权

US08764796B2 Suture method 有权
标题翻译：缝合法
公开(公告)号：US08764796B2
公开(公告)日：2014-07-01
申请号：US11307520
申请日：2006-02-10
申请人： Andrew Kaplan , Gregory L Ruff , Jeffrey C. Leung , Matthew A. Megaro
发明人： Andrew Kaplan , Gregory L Ruff , Jeffrey C. Leung , Matthew A. Megaro
IPC分类号： A61B17/04
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/04 , A61B17/06061 , A61B17/06166 , A61B17/062 , A61B17/1114 , A61B17/1146 , A61B2017/00575 , A61B2017/0061 , A61B2017/00632 , A61B2017/00663 , A61B2017/00792 , A61B2017/06052 , A61B2017/06057 , A61B2017/06171 , A61B2017/06176 , A61B2017/1135
摘要： A method for joining and holding closed a wound in bodily tissue, fastening junctions of wounds, tying off wounds, joining a foreign element to tissue, and altering the position of tissue using a barbed suture including sharp pointed ends. Each end of the suture includes barbs on that permit movement in an opposing direction to the barbs on the other end of the suture. This two-way barbed suture is used by the method of the present invention in applications including abdominal surgeries such as a Nissen fundoplication, laparoscopic uses such as stabilizing a bowel structure and performing a closure of a cystostomy, liver to bowel anastomosis, closure of an orifice of a Zenker's Diverticulum, endoscopic uses such as closure of ulcerative lesions or and post-procedural tissue defects, bladder wound closure, valve replacement surgery, device attachment, cosmetic surgery, and blood vessel wound closure.
摘要翻译：用于接合和保持身体组织中的伤口闭合的方法，紧固伤口的连接点，将伤口束紧，将异物连接到组织，以及使用包括尖锐尖端的带刺的缝合线改变组织的位置。缝合线的每个端部都包括有倒钩，允许在与缝合线另一端上的倒钩相反的方向上移动。这种双向有倒刺的缝合线用于本发明的方法中，包括腹部手术如尼森基底层切开术，腹腔镜用途如稳定肠结构并执行闭合膀胱造口术，肝脏排便吻合，闭合 Zenker憩室的孔，内窥镜使用，例如关闭溃疡性病变或术后组织缺陷，膀胱伤口闭合，瓣膜置换手术，装置附着，整容手术和血管伤口闭合。

5. 发明申请

US20130245684A1 SUTURE METHODS AND DEVICES 有权
标题翻译：搜索方法和设备
公开(公告)号：US20130245684A1
公开(公告)日：2013-09-19
申请号：US13796762
申请日：2013-03-12
申请人： Gregory L. Ruff , Jeffrey C. Leung , Andrew Kaplan , Matthew A. Megaro , Stanton D. Batchelor
发明人： Gregory L. Ruff , Jeffrey C. Leung , Andrew Kaplan , Matthew A. Megaro , Stanton D. Batchelor
IPC分类号： A61B17/06
CPC分类号： A61B17/06166 , A61B17/04 , A61B17/0401 , A61B17/06 , A61B17/064 , A61B17/11 , A61B17/1146 , A61B2017/00761 , A61B2017/0412 , A61B2017/0417 , A61B2017/0462 , A61B2017/0464 , A61B2017/06057 , A61B2017/06171 , A61B2017/06176
摘要： A barbed suture including a body with barbs on the periphery, a pointed end, and an anchor at one end to resist movement of the suture in the direction of the pointed end is provided. One or more limbs on the anchor may be provided, which may be arcuate, of varying lengths, and of varying distribution about the periphery of the suture body. Other anchor designs are provided. Methods of placing single-directional and bi-directional barbed sutures to approximate the tissue on each side of a wound and to position and support tissue in the absence of a wound, as in cosmetic surgery, are provided, and may include terminal J-stitches or S-stitches. Methods of placement may be made with sharp, pointed ends, which may be needles, or insertion devices. Sinusoidal patterns of sutures that have amplitudes generally perpendicular to the resultant holding force of the suture are provided.
摘要翻译：提供了一种带倒钩的缝合线，其包括在周边具有倒刺的身体，尖端和在一端的锚固件，以阻止缝合线在尖端的方向上的移动。可以提供锚固件上的一个或多个四肢，其可以是弓形的，具有不同长度，并且围绕缝合线主体的周边具有不同的分布。提供其他锚设计。提供单向和双向有倒钩缝合线近似伤口每侧的组织并且在整个外科手术中不存在伤口的位置和支撑组织的方法，并且可以包括端子J-针或S针。可以使用尖的尖端（可以是针或插入装置）来进行放置方法。提供具有大致垂直于缝合线的所得夹持力的振幅的缝合线的正弦图案。

6. 发明授权

US07857829B2 Suture method 有权
标题翻译：缝合法
公开(公告)号：US07857829B2
公开(公告)日：2010-12-28
申请号：US11747707
申请日：2007-05-11
申请人： Andrew Kaplan , Gregory L. Ruff , Jeffrey C. Leung , Matthew A. Megaro
发明人： Andrew Kaplan , Gregory L. Ruff , Jeffrey C. Leung , Matthew A. Megaro
IPC分类号： A61B17/04
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/04 , A61B17/06061 , A61B17/06166 , A61B17/062 , A61B17/1114 , A61B17/1146 , A61B2017/00575 , A61B2017/0061 , A61B2017/00632 , A61B2017/00663 , A61B2017/00792 , A61B2017/06052 , A61B2017/06057 , A61B2017/06171 , A61B2017/06176 , A61B2017/1135
摘要： A method is provided for performing a procedure to reposition a portion of a breast using a suture including a plurality of barbs. The barbs on a first portion of the suture adjacent a first end of the suture permit movement of the suture through tissue in a direction of movement of the first end and prevent movement of the suture through tissue in a direction opposite the direction of movement of the first end. The barbs on a second portion of the suture adjacent a second end of the suture permit movement of the suture through tissue in a direction of movement of the second end and prevent movement of the suture through tissue in a direction opposite the direction of movement of the second end. The method comprises the steps of inserting the first end of the suture through a first insertion point and causing the first portion of the suture to engage a tissue, inserting the second end of the suture through the first insertion point and advancing the second end of the suture through breast tissue to a first exit point located on the breast caudally of the first insertion point, and manually grouping and advancing the breast tissue relative to the suture towards the first insertion point to reposition a portion of the breast tissue.
摘要翻译：提供了一种用于执行使用包括多个倒钩的缝合线来重新定位乳房的一部分的过程的方法。邻近缝合线第一端的缝合线的第一部分上的倒钩允许缝线穿过组织沿着第一端的运动方向的运动，并且防止缝线穿过组织在与...的运动方向相反的方向上移动第一端邻近缝合线第二端的缝合线的第二部分上的倒钩允许缝线穿过组织沿着第二端的运动方向的运动，并且防止缝线穿过组织沿着与第二端的移动方向相反的方向运动第二端该方法包括以下步骤：通过第一插入点插入缝合线的第一端并使缝合线的第一部分接合组织，将缝合线的第二端插入穿过第一插入点并推进缝合线的第二端通过乳房组织缝合到位于第一插入点处的乳房上的第一出口点，并且相对于缝合线手动地将乳房组织分组并前进到第一插入点以重新定位乳房组织的一部分。

7. 发明申请

US20100298848A1 CONTINUOUS STITCH WOUND CLOSURE UTILIZING ONE-WAY SUTURE 有权
标题翻译：连续缝合使用一体式封口
公开(公告)号：US20100298848A1
公开(公告)日：2010-11-25
申请号：US12850186
申请日：2010-08-04
申请人： Jeffrey C. Leung , Matthew A. Megaro , Gregory Ruff , Andrew Kaplan
发明人： Jeffrey C. Leung , Matthew A. Megaro , Gregory Ruff , Andrew Kaplan
IPC分类号： A61B17/06
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/04 , A61B17/06061 , A61B17/06166 , A61B17/062 , A61B17/1114 , A61B17/1146 , A61B2017/00575 , A61B2017/0061 , A61B2017/00632 , A61B2017/00663 , A61B2017/00792 , A61B2017/06052 , A61B2017/06057 , A61B2017/06171 , A61B2017/06176 , A61B2017/1135
摘要： Continuous wound-closure techniques use one-way suture. The one-way suture has tissue-grasping surface features which allow passage of the suture in one direction through tissue, but not in the opposite direction. In closing a wound, the one-way suture is passed alternately through tissue on opposed sides of the wound. The wound-closure techniques allow approximation of the sides of the wound without knots, avoid loop stitching and reduce scarring.
摘要翻译：连续创伤闭合技术使用单向缝合。单向缝合线具有组织抓握表面特征，其允许缝合线在一个方向上穿过组织而不是相反方向。在关闭伤口时，单向缝合线交替穿过伤口相对侧上的组织。伤口闭合技术允许伤口侧面近似，无结，避免环路缝合并减少疤痕。

8. 发明授权

US08777989B2 Subcutaneous sinusoidal wound closure utilizing one-way suture 有权
标题翻译：使用单向缝合的皮下正弦伤口闭合
公开(公告)号：US08777989B2
公开(公告)日：2014-07-15
申请号：US12850336
申请日：2010-08-04
申请人： Jeffrey C. Leung , Matthew A. Megaro , Gregory Ruff , Andrew Kaplan
发明人： Jeffrey C. Leung , Matthew A. Megaro , Gregory Ruff , Andrew Kaplan
IPC分类号： A61B17/04
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/04 , A61B17/06061 , A61B17/06166 , A61B17/062 , A61B17/1114 , A61B17/1146 , A61B2017/00575 , A61B2017/0061 , A61B2017/00632 , A61B2017/00663 , A61B2017/00792 , A61B2017/06052 , A61B2017/06057 , A61B2017/06171 , A61B2017/06176 , A61B2017/1135
摘要： Subcutaneous sinusoidal wound-closure techniques use one-way sutures. The one-way sutures have tissue-grasping surface features which allow passage of the suture in one direction through tissue, but not in the opposite direction. In closing a wound, the one-way suture is deployed along a curvilinear path which passes alternately through subcutaneous tissue on opposed sides of the wound. The wound-closure techniques allow approximation of the sides of the wound without knots, avoid loop stitching and reduce scarring.
摘要翻译：皮下正弦伤口闭合技术使用单向缝合线。单向缝合线具有组织抓握表面特征，其允许缝合线在一个方向上通过组织但不是相反的方向。在闭合伤口时，单向缝合线沿着曲线路径展开，该曲线路径交替地穿过伤口相对侧上的皮下组织。伤口闭合技术允许伤口侧面近似，无结，避免环路缝合并减少疤痕。

9. 发明授权

US08777988B2 Methods for using self-retaining sutures in endoscopic procedures 有权
标题翻译：在内窥镜手术中使用自固定缝合线的方法
公开(公告)号：US08777988B2
公开(公告)日：2014-07-15
申请号：US12850263
申请日：2010-08-04
申请人： Jeffrey C. Leung , Matthew A. Megaro , Gregory Ruff , Andrew Kaplan
发明人： Jeffrey C. Leung , Matthew A. Megaro , Gregory Ruff , Andrew Kaplan
IPC分类号： A61B17/04
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/04 , A61B17/06061 , A61B17/06166 , A61B17/062 , A61B17/1114 , A61B17/1146 , A61B2017/00575 , A61B2017/0061 , A61B2017/00632 , A61B2017/00663 , A61B2017/00792 , A61B2017/06052 , A61B2017/06057 , A61B2017/06171 , A61B2017/06176 , A61B2017/1135
摘要： Endoscopic methods utilize self-retaining sutures to approximate tissue in a cavity of a subject. An endoscopic instrument is provided containing the self-retaining suture. The endoscopic instrument may be provided in combination with an endoscope and/or an endoscopic manipulator. The endoscopic instrument is passed through a cavity wall into a cavity of a patient. The self-retaining suture is deployed, using the endoscopic instrument, into a first tissue portion and a second tissue portion within the cavity. The self-retaining suture may be deployed endoscopically in patterns which include, purse string stitch, alpha stitch, linear stitching, curvilinear stitching, continuous helical stitch, and continuous sinusoidal stitch.
摘要翻译：内窥镜方法利用自我保留缝线来近视受试者空腔中的组织。提供含有自固位缝线的内窥镜器械。内窥镜器械可以与内窥镜和/或内窥镜操纵器组合提供。内窥镜器械通过腔壁进入患者的空腔。使用内窥镜器械将自固位缝合线部署到腔内的第一组织部分和第二组织部分中。自固位缝合线可以以内窥镜方式展开，其中包括：线圈缝合，阿尔法线迹，线性缝合，曲线缝合，连续螺旋线迹和连续正弦线迹。

10. 发明授权

US08764776B2 Anastomosis method using self-retaining sutures 有权
标题翻译：使用自我保留缝线的吻合方法
公开(公告)号：US08764776B2
公开(公告)日：2014-07-01
申请号：US12850362
申请日：2010-08-04
申请人： Jeffrey C. Leung , Matthew A. Megaro , Gregory Ruff , Andrew Kaplan
发明人： Jeffrey C. Leung , Matthew A. Megaro , Gregory Ruff , Andrew Kaplan
IPC分类号： A61B17/08
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/04 , A61B17/06061 , A61B17/06166 , A61B17/062 , A61B17/1114 , A61B17/1146 , A61B2017/00575 , A61B2017/0061 , A61B2017/00632 , A61B2017/00663 , A61B2017/00792 , A61B2017/06052 , A61B2017/06057 , A61B2017/06171 , A61B2017/06176 , A61B2017/1135
摘要： An anastomosis procedure utilizes a self-retaining suture to secure one vessel to another vessel. One or more self-retaining sutures are deployed around the interface between the vessels. The self-retaining sutures have tissue-grasping surface features which allow passage of the sutures in one direction through tissue, but not in the opposite direction. The self-retaining sutures may be deployed using a needle attached to the end of the sutures. The anastomosis technique may be performed without using knots.
摘要翻译：吻合手术利用自固定缝线将一个血管固定到另一个血管。在容器之间的界面周围部署一个或多个自固定缝合线。自固定缝合线具有组织抓握表面特征，其允许缝合线在一个方向上穿过组织而不是相反方向。可以使用附接到缝线末端的针来部署自固定缝合线。可以在不使用结的情况下进行吻合技术。

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