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    • 8. 发明申请
    • System and Apparatus for Continuous Monitoring of Movement Disorders
    • 用于连续监测运动障碍的系统和装置
    • US20100145236A1
    • 2010-06-10
    • US12632778
    • 2009-12-07
    • Andrew GreenbergJames McNamesPedro Mateo Riobo Aboy
    • Andrew GreenbergJames McNamesPedro Mateo Riobo Aboy
    • A61B5/11
    • G04G21/025A61B5/0002A61B5/1101A61B5/1118A61B5/681A61B2560/029A61B2560/0456A61B2560/0475A61B2562/0219G01S5/0257G01S5/0294G01S19/42
    • Disclosed embodiments include a complete system and platform which allows for continuous monitoring of movement disorders during normal daily activities in the clinic, home, and other normal daily environments. The system comprises: 1) a wearable apparatus for continuous monitoring of movement disorders, 2) a docking station, 3) a web server, and 4) methods for statistical analysis that generate movement impairment measures. Disclosed embodiments include a wearable movement monitoring apparatus comprising of (a) a sensor module including a plurality of low power micro-electromechanical systems kinematics sensors; (b) a microprocessor module including a low power microcontroller configured for device control, device status, and device communication; (c) a data storage module including a solid state local storage medium; (d) a wireless communication module including a low power surface mount transceiver and an integrated antenna; and (e) a power and docking module including a battery, an energy charging regulator circuit, and a docking connector.
    • 公开的实施例包括完整的系统和平台,其允许在诊所,家庭和其他正常日常环境中的正常日常活动期间连续监测运动障碍。 该系统包括:1)用于连续监测运动障碍的穿戴式装置,2)对接站,3)网络服务器,以及4)产生运动损伤测量的统计分析方法。 公开的实施例包括一种可穿戴运动监测装置,包括:(a)包括多个低功率微机电系统运动传感器的传感器模块; (b)微处理器模块,其包括被配置用于设备控制,设备状态和设备通信的低功率微控制器; (c)包括固态本地存储介质的数据存储模块; (d)包括低功率表面安装收发器和集成天线的无线通信模块; 和(e)包括电池,能量充电调节器电路和对接连接器的电力和​​对接模块。
    • 9. 发明授权
    • Method and apparatus for assessment of fluid responsiveness
    • 评估液体反应性的方法和装置
    • US08529458B2
    • 2013-09-10
    • US12891795
    • 2010-09-27
    • Sunghan KimPedro Mateo Riobo AboyJames McNames
    • Sunghan KimPedro Mateo Riobo AboyJames McNames
    • A61B5/02
    • A61B5/0205A61B5/412A61B5/4848A61B2505/03
    • Methods and apparatus for determining a cardiac parameter from cardiovascular pressure signals including arterial blood pressure (ABP) and the photoplethysmographic signal to quantify the degree of amplitude modulation due to respiration and predict fluid responsiveness are disclosed. Disclosed embodiments include a method for assessing fluid responsiveness implemented in a digital computer with one or more processors comprising: (a) measuring a cardiovascular signal, and (b) computing a dynamic index predictive of fluid responsiveness from said cardiovascular signal using a nonlinear state space estimator. According to one particular embodiment, and without limitation, the nonlinear state space estimator is based on a model for cardiovascular signals such as arterial blood pressure or plethysmogram signals, and employs a marginalized particle filter to estimate a dynamic index predictive of fluid responsiveness that is substantially equivalent to a variation in pulse pressure of said cardiovascular signal.
    • 公开了用于从心血管压力信号(包括动脉血压(ABP))和光电体积描记信号确定心脏参数的方法和装置,以量化由呼吸引起的幅度调制程度并预测流体反应性。 公开的实施例包括用于评估在具有一个或多个处理器的数字计算机中实现的流体响应性的方法,包括:(a)测量心血管信号,以及(b)使用非线性状态空间计算预测来自所述心血管信号的流体响应性的动态指数 估计。 根据一个特定实施例,非限制性地,非线性状态空间估计器基于诸如动脉血压或体积描记信号的心血管信号的模型,并且使用边缘化的粒子滤波器来估计预测流体响应性的动态指数,其基本上 相当于所述心血管信号的脉压的变化。