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    • 1. 发明授权
    • Tissue imaging system
    • 组织成像系统
    • US07460248B2
    • 2008-12-02
    • US11383254
    • 2006-05-15
    • Andrew F. KurtzJoseph R. BietryPaul O. McLaughlin
    • Andrew F. KurtzJoseph R. BietryPaul O. McLaughlin
    • G01B9/02G01B11/02
    • A61B5/0059A61B5/0066A61B5/412A61B5/445G01N21/21G01N21/23G01N21/4795G01N21/6458G01N21/6486
    • A tissue imaging system (200) for examining the medical condition of tissue (290) has an illumination optical system (205), which comprises a light source (220), having one or more light emitters, beam shaping optics, and polarizing optics. An optical beamsplitter (260) directs illumination light to an imaging sub-system, containing a spatial light modulator array (300). An objective lens (325) images illumination light from the spatial light modulator array to the tissue. An optical detection system (210) images the spatial light modulator to an optical detector array. A controller (360) drives the spatial light modulator to provide time variable arrangements of on-state pixels. The objective lens operates in a nominally telecentric manner relative to both the spatial light modulator and the tissue. The polarizing optics are independently and iteratively rotated to define variable polarization states relative to the tissue. The modulator pixels optically function like pinholes relative to the illumination light and the image light.
    • 用于检查组织(290)的医学状况的组织成像系统(200)具有照明光学系统(205),其包括具有一个或多个光发射器,光束整形光学器件和偏振光学器件的光源(220)。 光分束器(260)将照明光引导到包含空间光调制器阵列(300)的成像子系统。 物镜(325)将来自空间光调制器阵列的照明光图像转印到组织。 光学检测系统(210)将空间光调制器成像到光学检测器阵列。 控制器(360)驱动空间光调制器以提供导通状态像素的时间可变布置。 物镜相对于空间光调制器和组织以标称远心方式工作。 偏振光学器件被独立地并且迭代地旋转以限定相对于组织的可变极化状态。 调制器像素相对于照明光和图像光光学地起着像针孔的作用。
    • 3. 发明授权
    • Designing lenses using stress birefringence performance criterion
    • 使用应力双折射性能标准设计镜片
    • US08504328B2
    • 2013-08-06
    • US12784521
    • 2010-05-21
    • Joseph R. BietryAndrew F. KurtzBarry D. SilversteinJames Mazzarella
    • Joseph R. BietryAndrew F. KurtzBarry D. SilversteinJames Mazzarella
    • G06F17/50
    • G02B7/028G02B13/16G02B13/22
    • A method for designing an imaging lens having reduced susceptibility to thermally-induced stress birefringence, the imaging lens having first and second groups of lens elements located either side of an aperture stop, the method comprising: defining a set of lens design attributes; defining a set of lens performance criteria including a thermally-induced stress birefringence performance criterion; defining a first set of candidate glasses having a negligible susceptibility to thermal stress birefringence and a second set of candidate glasses having at most a moderate susceptibility to thermal stress birefringence; selecting glasses for lens elements that are located adjacent to the aperture stop from the first set of candidate glasses; selecting glasses for the remaining lens elements from the first or second sets of candidate glasses; and using a computer processor to determine a lens design for the imaging lens.
    • 一种用于设计对热诱导应力双折射具有降低的敏感性的成像透镜的方法,所述成像透镜具有位于孔径光阑的任一侧的第一和第二组透镜元件,所述方法包括:限定一组透镜设计属性; 定义一组透镜性能标准,包括热诱导应力双折射性能标准; 限定对热应力双折射具有可忽略的敏感性的第一组候选眼镜和对热应力双折射具有至多中度敏感性的第二组候选眼镜; 从第一组候选眼镜选择邻近孔径光阑的透镜元件的眼镜; 从第一组或第二组候选眼镜中选择剩余透镜元件的眼镜; 并使用计算机处理器来确定用于成像透镜的透镜设计。
    • 5. 发明授权
    • Low thermal stress birefringence imaging lens
    • 低热应力双折射成像透镜
    • US08649094B2
    • 2014-02-11
    • US12784520
    • 2010-05-21
    • Andrew F. KurtzJoseph R. BietryBarry D. Silverstein
    • Andrew F. KurtzJoseph R. BietryBarry D. Silverstein
    • G02B5/30G02B27/28G02B3/00G02B9/00
    • G02B1/00G02B5/3083G02B7/008G02B7/028G02B13/16G02B13/22G02B17/08G02B27/283
    • An imaging lens having reduced susceptibility to thermally-induced stress birefringence for imaging an object plane to an image plane; comprising: an aperture stop positioned between the object plane and the image plane; a first group of lens elements located on the object plane side of the aperture stop; and a second group of lens elements located on the image plane side of the aperture stop; wherein the lens elements immediately adjacent to the aperture stop are fabricated using glasses having a negligible susceptibility to thermal stress birefringence as characterized by a thermal stress birefringence metric; and wherein the other lens elements in the first or second groups of lens elements are fabricated using glasses having at most a moderate susceptibility to thermal stress birefringence as characterized by the thermal stress birefringence metric.
    • 一种成像透镜,其具有降低的用于将物平面成像到图像平面的热应力双折射的敏感性; 包括:位于物平面和图像平面之间的孔径光阑; 位于孔径光阑的物平面侧的第一组透镜元件; 以及位于所述孔径光阑的像面侧的第二组透镜元件; 其中紧邻孔径光阑的透镜元件使用对热应力双折射敏感性可忽略的玻璃制造,其特征在于热应力双折射度量; 并且其中第一组或第二组透镜元件中的其它透镜元件使用对热应力双折射度数表征的热应力双折射的中等敏感度的玻璃来制造。
    • 6. 发明授权
    • Out-of-plane motion of speckle reduction element
    • 斑点减少元件的平面外运动
    • US08366281B2
    • 2013-02-05
    • US12469766
    • 2009-05-21
    • Barry D. SilversteinGary E. NothhardJoseph R. BietryRobert MetzgerAndrew F. Kurtz
    • Barry D. SilversteinGary E. NothhardJoseph R. BietryRobert MetzgerAndrew F. Kurtz
    • G03B21/14
    • G02B27/48G02B3/0056G02B5/02G03B21/2033G03B21/208G03B33/06H04N9/3161
    • In a coherent light projection system including an image forming system, a relay system, a speckle reduction element, and a projection subsystem, the relay system can have a first f-number, and the projection subsystem can have a second f-number less than the first f-number. The relay system can have a first working distance, and the projection subsystem can have a second working distance less than the first working distance. The image forming system can project an initial image having a first size, and an intermediate image can have a second size greater than or equal to the first size. The speckle reduction element can have a curved surface through which the intermediate image is transferred. The speckle reduction element can include a lenslet arrangement formed on a surface thereof. The speckle reduction element can be moved in a direction parallel to an optical axis of the speckle reduction element.
    • 在包括图像形成系统,中继系统,散斑减少元件和投影子系统的相干光投射系统中,中继系统可以具有第一f数,并且投影子系统可以具有小于 第一个f号码。 继电器系统可以具有第一工作距离,并且投影子系统可以具有小于第一工作距离的第二工作距离。 图像形成系统可以投影具有第一尺寸的初始图像,并且中间图像可以具有大于或等于第一尺寸的第二尺寸。 斑点减少元件可以具有中间图像被转印通过的弯曲表面。 斑点减少元件可以包括在其表面上形成的小透镜布置。 斑点减少元件可以在平行于散斑减少元件的光轴的方向上移动。