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1. 发明授权

US07814805B2 Automated pipette machine 有权
标题翻译：自动移液器
公开(公告)号：US07814805B2
公开(公告)日：2010-10-19
申请号：US12164209
申请日：2008-06-30
申请人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
发明人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
IPC分类号： G01N1/14 , G01N35/10 , B01L3/02
CPC分类号： B01L3/0279 , B01L2200/023 , B01L2200/0689 , G01N35/10
摘要： A pipette nozzle is provided for use on a movable arm on an automated pipette machine. The pipette nozzle includes a body defining a passage therethrough and having at least two seating surfaces provided on the body. The first seating surface is configured to receive and sealingly mate with a first size of pipette tip in a manner such that the first end of the passage is in fluid communication with the first size of pipette tip. The second seating surface is configured to correspondingly receive, sealingly mate and provide passage first end fluid communication with a second size of pipette tip. There is also provided an automated pipette machine which includes a tip ejector system including an arm that is movable between a first position and a second position wherein in the first position the arm is positioned to engage the tip during movement of the nozzle along a selected path and to prevent movement of the tip along the selected path while permitting the nozzle to move along the selected path, so that the movement of the nozzle along the selected path causes the nozzle and the tip to disengage from each other, and wherein in the second position the arm is positioned to avoid engagement with the tip during movement of the nozzle.
摘要翻译：提供移液管喷嘴用于自动移液管机上的可移动臂上。移液管喷嘴包括限定穿过其中的通道的主体，并且具有设置在主体上的至少两个就座表面。第一座面被构造成以使得通道的第一端与第一尺寸的移液管尖端流体连通的方式接收并密封地与第一尺寸的移液管尖端配合。第二座面构造成相应地接收，密封地配合并提供与第二尺寸的移液管尖端的通道第一端流体连通。还提供了一种自动移液器机器，其包括尖端喷射器系统，其包括可在第一位置和第二位置之间移动的臂，其中在第一位置中臂被定位成在沿着选定路径的喷嘴运动期间接合尖端并且防止尖端沿着所选择的路径运动，同时允许喷嘴沿着所选择的路径移动，使得喷嘴沿着所选路径的移动导致喷嘴和尖端彼此脱离，并且其中在第二位置是使臂被定位成避免在喷嘴运动期间与尖端接合。

2. 发明申请

US20080295618A1 AUTOMATED PIPETTE MACHINE 有权
公开(公告)号：US20080295618A1
公开(公告)日：2008-12-04
申请号：US12189552
申请日：2008-08-11
申请人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
发明人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
IPC分类号： B01L3/02 , G01N1/14
CPC分类号： B01L3/0279 , B01L2200/023 , B01L2200/0689 , G01N35/10
摘要： A pipette nozzle is provided for use on a movable arm on an automated pipette machine. The pipette nozzle includes a body defining a passage therethrough. At least two seating surfaces are provided on the body, including a first seating surface and a second seating surface. The first seating surface is configured to receive and sealingly mate with a first size of pipette tip in a manner such that the first end of the passage is in fluid communication with the first size of pipette tip. The second seating surface is configured to receive and sealingly mate with a second size of pipette tip in a manner such that the first end of the passage is in fluid communication with the second size of pipette tip. There is also provided an automated pipette machine which includes a tip ejector system including an arm that is movable between a first position and a second position, wherein in the first position the arm is positioned to engage the tip during movement of the nozzle along a selected path and to prevent movement of the tip along the selected path while permitting the nozzle to move along the selected path, so that the movement of the nozzle along the selected path causes the nozzle and the tip to disengage from each other, and wherein in the second position the arm is positioned to avoid engagement with the tip during movement of the nozzle. There is also provided an apparatus for use on an automated pipette machine for transmitting pressure changes produced by a pump on the machine to a pipette nozzle. The apparatus comprises a housing defining a chamber a first conduit and a second conduit. The first conduit extends into the chamber and has a first opening positioned in the chamber. The first conduit is fluidically connectible to the nozzle. The second conduit extends into the chamber and has a first opening positioned in the chamber. The second conduit is fluidically connectible to the pump. The first opening of the first conduit is positioned above the first opening of the second conduit. The chamber defines at least a selected volume between the height of the first opening of the first conduit and the height of the first opening of the second conduit.

3. 发明申请

US20080264187A1 AUTOMATED PIPETTE MACHINE 有权
公开(公告)号：US20080264187A1
公开(公告)日：2008-10-30
申请号：US12164154
申请日：2008-06-30
申请人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
发明人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
IPC分类号： B01L3/02
CPC分类号： B01L3/0279 , B01L2200/023 , B01L2200/0689 , G01N35/10
摘要： A pipette nozzle is provided for use on a movable arm on an automated pipette machine. The pipette nozzle includes a body defining a passage therethrough. At least two seating surfaces are provided on the body, including a first seating surface and a second seating surface. The first seating surface is configured to receive and sealingly mate with a first size of pipette tip in a manner such that the first end of the passage is in fluid communication with the first size of pipette tip. The second seating surface is configured to receive and sealingly mate with a second size of pipette tip in a manner such that the first end of the passage is in fluid communication with the second size of pipette tip. There is also provided an automated pipette machine which includes a tip ejector system including an arm that is movable between a first position and a second position, wherein in the first position the arm is positioned to engage the tip during movement of the nozzle along a selected path and to prevent movement of the tip along the selected path while permitting the nozzle to move along the selected path, so that the movement of the nozzle along the selected path causes the nozzle and the tip to disengage from each other, and wherein in the second position the arm is positioned to avoid engagement with the tip during movement of the nozzle. There is also provided an apparatus for use on an automated pipette machine for transmitting pressure changes produced by a pump on the machine to a pipette nozzle. The apparatus comprises a housing defining a chamber a first conduit and a second conduit. The first conduit extends into the chamber and has a first opening positioned in the chamber. The first conduit is fluidically connectible to the nozzle. The second conduit extends into the chamber and has a first opening positioned in the chamber. The second conduit is fluidically connectible to the pump. The first opening of the first conduit is positioned above the first opening of the second conduit. The chamber defines at least a selected volume between the height of the first opening of the first conduit and the height of the first opening of the second conduit.

4. 发明授权

US07819029B2 Automated pipette machine 有权
标题翻译：自动移液器
公开(公告)号：US07819029B2
公开(公告)日：2010-10-26
申请号：US12164154
申请日：2008-06-30
申请人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
发明人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
IPC分类号： G01N1/14 , B01L3/02 , G01N35/10
CPC分类号： B01L3/0279 , B01L2200/023 , B01L2200/0689 , G01N35/10
摘要： There is also provided an apparatus for use on an automated pipette machine for transmitting pressure changes produced by a pump on the machine to a pipette nozzle. The apparatus comprises a housing defining a chamber a first conduit and a second conduit. The first conduit extends into the chamber and has a first opening positioned in the chamber. The first conduit is fluidically connectible to the nozzle. The second conduit extends into the chamber and has a first opening positioned in the chamber. The second conduit is fluidically connectible to the pump. The first opening of the first conduit is positioned above the first opening of the second conduit. The chamber defines at least a selected volume between the height of the first opening of the first conduit and the height of the first opening of the second conduit.
摘要翻译：还提供了一种用于自动移液器的用于将由机器上的泵产生的压力变化传递到移液管喷嘴的装置。该装置包括限定腔室的壳体，第一导管和第二导管。第一导管延伸到腔室中并且具有位于腔室中的第一开口。第一导管可流体地连接到喷嘴。第二导管延伸到腔室中并且具有位于腔室中的第一开口。第二导管可流体地连接到泵。第一导管的第一开口位于第二导管的第一开口的上方。腔室限定第一导管的第一开口的高度与第二导管的第一开口的高度之间的至少一个选定的体积。

5. 发明申请

US20090007703A1 AUTOMATED PIPETTE MACHINE 有权
公开(公告)号：US20090007703A1
公开(公告)日：2009-01-08
申请号：US12164209
申请日：2008-06-30
申请人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
发明人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
IPC分类号： G01N1/14
CPC分类号： B01L3/0279 , B01L2200/023 , B01L2200/0689 , G01N35/10
摘要： A pipette nozzle is provided for use on a movable arm on an automated pipette machine. The pipette nozzle includes a body defining a passage therethrough. At least two seating surfaces are provided on the body, including a first seating surface and a second seating surface. The first seating surface is configured to receive and sealingly mate with a first size of pipette tip in a manner such that the first end of the passage is in fluid communication with the first size of pipette tip. The second seating surface is configured to receive and sealingly mate with a second size of pipette tip in a manner such that the first end of the passage is in fluid communication with the second size of pipette tip. There is also provided an automated pipette machine which includes a tip ejector system including an arm that is movable between a first position and a second position, wherein in the first position the arm is positioned to engage the tip during movement of the nozzle along a selected path and to prevent movement of the tip along the selected path while permitting the nozzle to move along the selected path, so that the movement of the nozzle along the selected path causes the nozzle and the tip to disengage from each other, and wherein in the second position the arm is positioned to avoid engagement with the tip during movement of the nozzle. There is also provided an apparatus for use on an automated pipette machine for transmitting pressure changes produced by a pump on the machine to a pipette nozzle. The apparatus comprises a housing defining a chamber a first conduit and a second conduit. The first conduit extends into the chamber and has a first opening positioned in the chamber. The first conduit is fluidically connectible to the nozzle. The second conduit extends into the chamber and has a first opening positioned in the chamber. The second conduit is fluidically connectible to the pump. The first opening of the first conduit is positioned above the first opening of the second conduit. The chamber defines at least a selected volume between the height of the first opening of the first conduit and the height of the first opening of the second conduit.

6. 发明申请

US20070180935A1 Automated pipette machine 审中-公开
公开(公告)号：US20070180935A1
公开(公告)日：2007-08-09
申请号：US11182741
申请日：2005-07-18
申请人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
发明人： Andrew Angus , Fred Davis , Adam Donath , Richard Grant , Dirk Kurpershoek
IPC分类号： B01L3/02 , G01N1/14
CPC分类号： B01L3/0279 , B01L2200/023 , B01L2200/0689 , G01N35/10
摘要： A pipette nozzle is provided for use on a movable arm on an automated pipette machine. The pipette nozzle includes a body defining a passage therethrough. At least two seating surfaces are provided on the body, including a first seating surface and a second seating surface. The first seating surface is configured to receive and sealingly mate with a first size of pipette tip in a manner such that the first end of the passage is in fluid communication with the first size of pipette tip. The second seating surface is configured to receive and sealingly mate with a second size of pipette tip in a manner such that the first end of the passage is in fluid communication with the second size of pipette tip. There is also provided an automated pipette machine which includes a tip ejector system including an arm that is movable between a first position and a second position, wherein in the first position the arm is positioned to engage the tip during movement of the nozzle along a selected path and to prevent movement of the tip along the selected path while permitting the nozzle to move along the selected path, so that the movement of the nozzle along the selected path causes the nozzle and the tip to disengage from each other, and wherein in the second position the arm is positioned to avoid engagement with the tip during movement of the nozzle. There is also provided an apparatus for use on an automated pipette machine for transmitting pressure changes produced by a pump on the machine to a pipette nozzle. The apparatus comprises a housing defining a chamber a first conduit and a second conduit. The first conduit extends into the chamber and has a first opening positioned in the chamber. The first conduit is fluidically connectible to the nozzle. The second conduit extends into the chamber and has a first opening positioned in the chamber. The second conduit is fluidically connectible to the pump. The first opening of the first conduit is positioned above the first opening of the second conduit. The chamber defines at least a selected volume between the height of the first opening of the first conduit and the height of the first opening of the second conduit.

7. 发明授权

US06093767A High shock absorbing rubber compositions 失效
标题翻译：高吸震橡胶组合物
公开(公告)号：US06093767A
公开(公告)日：2000-07-25
申请号：US190052
申请日：1998-11-10
申请人： Fred Davis , Zbig Z. Zivny
发明人： Fred Davis , Zbig Z. Zivny
IPC分类号： C08L9/02 , C08L21/00 , C08L23/16 , C08K3/36 , C08L23/32 , C08L35/04
CPC分类号： C08L21/00 , C08L23/16 , C08L9/02 , Y10T428/105
摘要： A high shock absorbing rubber composition comprises a cured blend of a conjugated diene rubber such as natural rubber or nitrile rubber with an EPDM rubber, and significant amounts of silica and optionally clay. The cured composition has low pendulum rebound properties of 20% or less, and is suitable for use as sport grips such as tennis rackets or golf grips, hand tools, lawn equipment, and the like.
摘要翻译：高吸震橡胶组合物包括共轭二烯橡胶如天然橡胶或丁腈橡胶与EPDM橡胶的固化共混物，以及显着量的二氧化硅和任选的粘土。固化的组合物的摆摆回弹性能低20％以下，适用于作为运动夹具如网球拍或高尔夫球把手，手动工具，草坪设备等。

8. 发明授权

US5666055A Surface coil system for a single channel NMR receiver 失效
标题翻译：用于单通道NMR接收器的表面线圈系统
公开(公告)号：US5666055A
公开(公告)日：1997-09-09
申请号：US537534
申请日：1995-10-02
申请人： Randall W. Jones , Fred Davis
发明人： Randall W. Jones , Fred Davis
IPC分类号： G01R33/3415 , G01V3/00
CPC分类号： G01R33/3664 , G01R33/3415
摘要： A surface coil system for single channel MRI reception comprising a coil system including a plurality of self-resonant, overlapping coil conductor sections arranged relative to one another and to anatomical regions of a patient such that a combination of regions form a desired larger region of interest, a control unit located remotely from the coil system and electromagnetically communicating therewith, having means for selectively electronically activating and deactivating each coil section to produce MRI output signals when activated, means for combining selected MRI output signals, and means for electrically connecting the coil system to an MRI system to transmit selected MRI signals to the MRI system.
摘要翻译：一种用于单通道MRI接收的表面线圈系统，包括线圈系统，该线圈系统包括相对于彼此布置的多个自谐振重叠线圈导体部分和患者的解剖区域，使得区域的组合形成期望的较大感兴趣区域，远离线圈系统并与其电磁通信的控制单元，具有用于选择性地电子地激活和去激活每个线圈段以在激活时产生MRI输出信号的装置，用于组合所选MRI输出信号的装置，以及用于电连接线圈系统的装置到MRI系统以将选定的MRI信号传输到MRI系统。

9. 发明授权

US5248243A Pneumatically operated and controlled fluid pump 失效
标题翻译：气动操作和控制流体泵
公开(公告)号：US5248243A
公开(公告)日：1993-09-28
申请号：US824832
申请日：1992-01-22
申请人： Richard Dyer , Fred Davis , Mark Hill , Ozell Purswell
发明人： Richard Dyer , Fred Davis , Mark Hill , Ozell Purswell
IPC分类号： F04F1/08 , F04F5/50
CPC分类号： F04F5/50 , F04F1/08
摘要： A pneumatically operated and controlled pump which is capable of maintaining its efficiency and reliability in various environments. The pump head contains a spool and sleeve valve assembly operated in response to a signal pressure. The assembly controls the cycling of the pump through a pumping phase and a pump filling phase. A timing switch on the surface controls the occurrence of the signal pressure and thus the pump cycles, at preset intervals thus eliminating any lag time between the cycles and the need for operator estimations of the cycle times. This results in a virtually closed system and self contained unit.
摘要翻译：一种气动和受控的泵，能够在各种环境中保持其效率和可靠性。泵头包含响应于信号压力操作的阀芯和套筒阀组件。组件通过泵送阶段和泵填充阶段来控制泵的循环。表面上的定时开关控制信号压力的发生，从而以预定的间隔控制泵循环，从而消除循环之间的任何滞后时间以及操作者对循环时间的估计的需要。这导致一个几乎封闭的系统和独立的单元。

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