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1. 发明授权

US07433473B2 Data transmission method between a broadcasting center and a multimedia unit 有权
标题翻译：广播中心与多媒体单元之间的数据传输方法
公开(公告)号：US07433473B2
公开(公告)日：2008-10-07
申请号：US11214833
申请日：2005-08-31
申请人： André Kudelski , Christophe Nicolas , Nicolas Fischer
发明人： André Kudelski , Christophe Nicolas , Nicolas Fischer
IPC分类号： H04L9/00
CPC分类号： H04N21/26606 , H04N21/25816
摘要： The aim of this invention is to propose a flexible solution to the risk represented by the interception of data by an unauthorized party during the transmission of said data between a broadcast center and a specialized decryption/decompression circuit such as is used in a Pay-TV decoder. This aim is achieved by a data transmission method involving a broadcast center or diffusion center, a management center and a multimedia unit, the latter comprising at least one unique key and a security module having a transport key.
摘要翻译：本发明的目的是提出一种在广播中心和专用解密/解压缩电路（例如在付费电视机中使用的）之间传输所述数据期间由未授权方截取数据所代表的风险的灵活解决方案解码器。该目的通过涉及广播中心或扩散中心，管理中心和多媒体单元的数据传输方法来实现，后者包括至少一个唯一密钥和具有传输密钥的安全模块。

2. 发明申请

US20060056632A1 Data transmission method between a broadcasting center and a multimedia unit 有权
标题翻译：广播中心与多媒体单元之间的数据传输方法
公开(公告)号：US20060056632A1
公开(公告)日：2006-03-16
申请号：US11214833
申请日：2005-08-31
申请人： Andre Kudelski , Christophe Nicolas , Nicolas Fischer
发明人： Andre Kudelski , Christophe Nicolas , Nicolas Fischer
IPC分类号： H04L9/00
CPC分类号： H04N21/26606 , H04N21/25816
摘要： The aim of this invention is to propose a flexible solution to the risk represented by access to a temporary memory of a specialized decryption/decompression circuit for a Pay-TV decoder. This aim is achieved by a data transmission method between a diffusion centre and a multimedia unit, the latter comprising at least one unique key and a security module having a transport key, this method comprising the following stages: generation of a session key by a management centre, transmission of the session key to the diffusion centre, encryption of the session key by the unique key of the multimedia unit, transmission of a message encrypted by the transport key comprising the encrypted session key to the multimedia unit, transmission of the message to the security module by the multimedia unit, decryption of the message by the transport key of the security module and transmission of the encrypted session key to the multimedia unit, decryption of the session key encrypted by the unique key of the multimedia unit, creation of a connection secured by the encryption and decryption, by the session key, of data exchanged between the diffusion centre and the multimedia unit.
摘要翻译：本发明的目的是提出一种灵活的解决方案，用于通过访问用于付费电视解码器的专用解密/解压缩电路的临时存储器所代表的风险。该目的通过扩散中心和多媒体单元之间的数据传输方法实现，后者包括至少一个唯一密钥和具有传输密钥的安全模块，该方法包括以下阶段：由管理层生成会话密钥中心，会话密钥传输到扩散中心，通过多媒体单元的唯一密钥加密会话密钥，通过包括加密会话密钥的传输密钥加密的消息传输到多媒体单元，将消息传输到多媒体单元的安全模块，通过安全模块的传输密钥对消息进行解密，并将加密的会话密钥发送到多媒体单元，解密由多媒体单元的唯一密钥加密的会话密钥，创建一个通过会话密钥加密和解密在扩散中心和多媒体单元之间交换的数据的连接。

3. 发明授权

US08673299B2 Anti-RANTES antibodies 有权
标题翻译：抗RANTES抗体
公开(公告)号：US08673299B2
公开(公告)日：2014-03-18
申请号：US13207774
申请日：2011-08-11
申请人： Nicolas Fischer , Marie Kosco-Vilbois , Francois Mach
发明人： Nicolas Fischer , Marie Kosco-Vilbois , Francois Mach
IPC分类号： A61K39/395 , C07K16/18 , C07K16/24
CPC分类号： C07K16/24 , A61K2039/505 , C07K2317/21 , C07K2317/30 , C07K2317/33 , C07K2317/52 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要： The invention relates to fully human monoclonal antibodies, and fragments thereof, that bind to the chemokine Regulated upon Activation, Normal T-cell Expressed, and Secreted (RANTES, CCL5), thereby modulating the interaction between RANTES and one of more of its receptors, such as, e.g., CCR1, CCR3, CCR4 and CCR5, and/or modulating the biological activities of RANTES. The invention also relates to the use of these or any anti-RANTES antibodies in the prevention or treatment of immune-related disorders and in the amelioration of one or more symptoms associated with an immune-related disorder.
摘要翻译：本发明涉及完全人单克隆抗体及其片段，其结合活化时调节的趋化因子，表达正常T细胞和分泌型（RANTES，CCL5），从而调节RANTES与其多个受体之一的相互作用，例如CCR1，CCR3，CCR4和CCR5，和/或调节RANTES的生物学活性。本发明还涉及这些或任何抗RANTES抗体在预防或治疗免疫相关疾病以及改善与免疫相关病症相关的一种或多种症状中的用途。

4. 发明申请

US20130279694A1 SYSTEM AND METHOD TO RECORD ENCRYPTED CONTENT WITH ACCESS CONDITIONS 有权
标题翻译：用访问条件记录加密内容的系统和方法
公开(公告)号：US20130279694A1
公开(公告)日：2013-10-24
申请号：US13990979
申请日：2011-12-01
申请人： Fabien Gremaud , Nicolas Fischer
发明人： Fabien Gremaud , Nicolas Fischer
IPC分类号： H04N7/167
CPC分类号： H04N7/167 , H04N21/4181 , H04N21/4334 , H04N21/4408
摘要： A television event may be consumed after been stored in a mass memory of a multimedia unit, but still fully relies on the security of a secure device. A conversion of a received content aims at firstly descrambling the content using control words included in entitlement control messages and immediately re-encrypting the descrambled content by a unique key generated specifically for this content. Access conditions attached to the entitlement control message containing the control word are temporarily stored and once the decryption is terminated, the secure device produces an information block. This information block containing for example access conditions and an identifier of the content is either stored into a secure memory of the secure device or stored in the mass memory with the encrypted content. The unique key is made up of a combination of a root key specific to the secure device and the information block.
摘要翻译：电视事件在被存储在多媒体单元的大容量存储器中之后可能被消耗，但是仍然完全依赖于安全设备的安全性。接收到的内容的转换旨在首先使用包括在授权控制消息中的控制字对内容进行解扰，并且通过专门针对该内容生成的唯一密钥立即重新加密解扰的内容。临时存储附加到包含控制字的授权控制消息的访问条件，一旦解密结束，则安全设备产生信息块。包含例如访问条件和内容的标识符的该信息块或者被存储到安全设备的安全存储器中或者存储在具有加密内容的大容量存储器中。唯一密钥由特定于安全设备的根密钥和信息块的组合组成。

5. 发明授权

US08037339B2 Security device intended to be connected to a processing unit for an audio/video signal and process using such a device 有权
标题翻译：旨在连接到用于音频/视频信号的处理单元和使用这种设备的处理的安全设备
公开(公告)号：US08037339B2
公开(公告)日：2011-10-11
申请号：US11802662
申请日：2007-05-24
申请人： Karl Osen , Nicolas Fischer
发明人： Karl Osen , Nicolas Fischer
IPC分类号： G06F1/04 , G06F15/177
CPC分类号： G06K19/07733 , G06K7/10297 , G06K19/07 , G06K19/073
摘要： Example embodiments relate to a security device having two communication interfaces sharing at least one pin, each interface being capable of operating according to either of two predetermined communication protocols. The security device may further include a frequency detector to detect the frequency of a clock signal on the shared pin. Depending on the value of the detected frequency, and to which of a plurality of predetermined frequency ranges the detected frequency pertains, the security device may function according to one of the two predetermined communication protocols, operating at two different frequencies.
摘要翻译：示例性实施例涉及具有共享至少一个引脚的两个通信接口的安全设备，每个接口能够根据两个预定通信协议中的任一个进行操作。安全装置还可以包括频率检测器，用于检测共享引脚上的时钟信号的频率。根据所检测的频率的值以及所检测的频率所属的多个预定频率范围中的哪一个，安全设备可以根据两个预定通信协议中的一个在两个不同的频率下工作。

6. 发明申请

US20090169561A1 Anti-IP-10 antibodies and methods of use thereof 有权
标题翻译：抗IP-10抗体及其使用方法
公开(公告)号：US20090169561A1
公开(公告)日：2009-07-02
申请号：US12072824
申请日：2008-02-28
申请人： Nicolas Fischer , Marie Kosco-Vilbois , Olivier Leger
发明人： Nicolas Fischer , Marie Kosco-Vilbois , Olivier Leger
IPC分类号： A61K39/395 , C07K16/18
CPC分类号： C07K16/24 , A61K2039/505 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The invention relates to fully human antibodies, and fragments thereof, that bind to interferon-inducible-protein-10 (IP-10, CXCL10), thereby modulating the interaction between IP-10 and its receptor, CXCR3, and/or modulating the biological activities of IP-10. The invention also relates to the use of such anti-IP-10 antibodies in the prevention or treatment of immune-related disorders and in the amelioration of one or more symptoms associated with an immune-related disorder.
摘要翻译：本发明涉及与干扰素诱导型蛋白-10（IP-10，CXCL10）结合的完全人抗体及其片段，从而调节IP-10与其受体CXCR3之间的相互作用和/或调节生物学 IP-10活动。本发明还涉及这样的抗-IP-10抗体在预防或治疗免疫相关病症中以及改善与免疫相关病症相关的一种或多种症状的用途。

7. 发明授权

US4091197A Process for polymerization of vinyl chloride micro-suspension with metal compounds 失效
标题翻译：用金属化合物聚合氯乙烯微悬浮液的方法
公开(公告)号：US4091197A
公开(公告)日：1978-05-23
申请号：US637938
申请日：1975-12-05
申请人： Nicolas Fischer , Jacques Boissel , Thomas Kemp , Henri Eyer
发明人： Nicolas Fischer , Jacques Boissel , Thomas Kemp , Henri Eyer
IPC分类号： C08F14/06 , C08F259/04 , C08F2/18 , C08F114/06 , C08F214/06
CPC分类号： C08F14/06 , C08F259/04 , Y10S526/909
摘要： Micro-suspension polymerization of vinyl chloride monomers and comonomers with a seed in the form of a previously prepared dispersion of the polymer or copolymer containing all of the organo-soluble initiator required for the polymerization, in which the initiator is activated during the polymerization by the addition of an organo-metallic complex of a water-soluble metal salt reacted with a complexing agent.
摘要翻译：以预先制备的聚合物或共聚物分散体形式的氯乙烯单体和共聚单体的微悬浮聚合，其包含聚合所需的所有有机可溶性引发剂，其中引发剂在聚合过程中被活化加入与络合剂反应的水溶性金属盐的有机金属络合物。

8. 发明授权

US08551478B2 Anti-CD3 antibodies and methods of use thereof 有权
标题翻译：抗CD3抗体及其使用方法
公开(公告)号：US08551478B2
公开(公告)日：2013-10-08
申请号：US12750385
申请日：2010-03-30
申请人： Bernard Mach , Yann Dean , Marie Kosco-Vilbois , Greg Elson , Nicolas Fischer , Olivier Leger
发明人： Bernard Mach , Yann Dean , Marie Kosco-Vilbois , Greg Elson , Nicolas Fischer , Olivier Leger
IPC分类号： A61K39/395
CPC分类号： C07K16/2809 , A61K39/3955 , A61K45/06 , C07K2317/21 , C07K2317/34 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/74
摘要： The present invention is related to antibodies directed to the antigen CD3 and uses of such antibodies. In particular, the present invention provides fully human monoclonal antibodies directed to CD3. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
摘要翻译：本发明涉及针对抗原CD3的抗体和这种抗体的用途。特别地，本发明提供了完全针对CD3的人单克隆抗体。编码的核苷酸序列和包含重链和轻链免疫球蛋白分子的氨基酸序列，特别是对应于跨越框架区和/或互补决定区（CDR）的连续重链和轻链序列的序列，特别是从FR1至FR4或CDR1至CDR3 ，提供。还提供了表达这种免疫球蛋白分子和单克隆抗体的杂交瘤或其它细胞系。

9. 发明申请

US20130216549A1 Anti-IP-10 Antibodies and Uses Thereof 审中-公开
标题翻译：抗IP-10抗体及其用途
公开(公告)号：US20130216549A1
公开(公告)日：2013-08-22
申请号：US13597644
申请日：2012-08-29
申请人： Nicolas Fischer , Marie Kosco-Vilbois , Olivier Leger
发明人： Nicolas Fischer , Marie Kosco-Vilbois , Olivier Leger
IPC分类号： C07K16/24
CPC分类号： C07K16/24 , A61K2039/505 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The invention relates to fully human antibodies, and fragments thereof, that bind to interferon-inducible-protein-10 (IP-10, CXCL10), thereby modulating the interaction between IP-10 and its receptor, CXCR3, and/or modulating the biological activities of IP-10. The invention also relates to the use of such anti-IP-10 antibodies in the prevention or treatment of immune-related disorders and in the amelioration of one or more symptoms associated with an immune-related disorder.
摘要翻译：本发明涉及与干扰素诱导型蛋白-10（IP-10，CXCL10）结合的完全人抗体及其片段，从而调节IP-10与其受体CXCR3之间的相互作用和/或调节生物学 IP-10活动。本发明还涉及这样的抗-IP-10抗体在预防或治疗免疫相关病症中以及改善与免疫相关病症相关的一种或多种症状的用途。

10. 发明授权

US08012474B2 Anti-RANTES antibodies 有权
标题翻译：抗RANTES抗体
公开(公告)号：US08012474B2
公开(公告)日：2011-09-06
申请号：US12221485
申请日：2008-08-04
申请人： Nicolas Fischer , Marie Kosco-Vilbois , Francois Mach
发明人： Nicolas Fischer , Marie Kosco-Vilbois , Francois Mach
IPC分类号： A61K39/395 , C07K16/18 , C07K16/24
CPC分类号： C07K16/24 , A61K2039/505 , C07K2317/21 , C07K2317/30 , C07K2317/33 , C07K2317/52 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要： The invention relates to fully human monoclonal antibodies, and fragments thereof, that bind to the chemokine Regulated upon Activation, Normal T-cell Expressed, and Secreted (RANTES, CCL5), thereby modulating the interaction between RANTES and one of more of its receptors, such as, e.g., CCR1, CCR3, CCR4 and CCR5, and/or modulating the biological activities of RANTES. The invention also relates to the use of these or any anti-RANTES antibodies in the prevention or treatment of immune-related disorders and in the amelioration of one or more symptoms associated with an immune-related disorder.
摘要翻译：本发明涉及完全人单克隆抗体及其片段，其结合活化时调节的趋化因子，表达正常T细胞和分泌型（RANTES，CCL5），从而调节RANTES与其多个受体之一的相互作用，例如CCR1，CCR3，CCR4和CCR5，和/或调节RANTES的生物学活性。本发明还涉及这些或任何抗RANTES抗体在预防或治疗免疫相关疾病以及改善与免疫相关病症相关的一种或多种症状中的用途。

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