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1. 发明申请

US20150284365A1 COMPOUNDS AND METHODS OF USE THEREOF 审中-公开
标题翻译：化合物及其使用方法
公开(公告)号：US20150284365A1
公开(公告)日：2015-10-08
申请号：US14532557
申请日：2014-11-04
申请人： Amy Elder , Geraldine Harriman , Silvana Leit , Jie Li , Howard P. Sard , Yiliang Zhang , Douglas Wilson
发明人： Amy Elder , Geraldine Harriman , Silvana Leit , Jie Li , Howard P. Sard , Yiliang Zhang , Douglas Wilson
IPC分类号： C07D403/04 , C07D401/12 , C07D409/12 , C07D413/06 , C07D405/04 , C07D401/04 , C07D409/06 , C07D401/06 , C07D209/16 , C07D409/04
CPC分类号： C07D403/04 , C07D209/16 , C07D209/24 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12 , C07D413/06 , C07D487/08 , C07D491/04
摘要： Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
摘要翻译：吲哚化合物被公开。还公开了使用该化合物治疗人和动物疾病的方法，化合物的药物组合物和包括该化合物的试剂盒。

2. 发明申请

US20170342054A1 COMPOUNDS AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：US20170342054A1
公开(公告)日：2017-11-30
申请号：US15399422
申请日：2017-01-05
申请人： Amy Elder , Geraldine Harriman , Silvana Leit , Jie Li , Howard P. Sard , Yiliang Zhang , Douglas Wilson
发明人： Amy Elder , Geraldine Harriman , Silvana Leit , Jie Li , Howard P. Sard , Yiliang Zhang , Douglas Wilson
IPC分类号： C07D403/04 , C07D209/16 , C07D413/06 , C07D409/12 , C07D409/06 , C07D409/04 , C07D405/12 , C07D405/06 , C07D405/04 , C07D403/06 , C07D401/12 , C07D401/06 , C07D401/04 , C07D209/24 , C07D487/08 , C07D491/04
CPC分类号： C07D403/04 , C07D209/16 , C07D209/24 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/04 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12 , C07D413/06 , C07D487/08 , C07D491/04
摘要： Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.

3. 发明授权

US09334263B2 Compositions useful for treating disorders related to kit 有权
标题翻译：用于治疗与试剂盒有关的疾病的组合物
公开(公告)号：US09334263B2
公开(公告)日：2016-05-10
申请号：US14517480
申请日：2014-10-17
申请人： Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu , Douglas Wilson , Yulian Zhang
发明人： Brian L. Hodous , Joseph L. Kim , Chandrasekhar V. Miduturu , Douglas Wilson , Yulian Zhang
IPC分类号： C07D403/14 , C07D401/14 , C07D413/14 , A61K31/53 , A61K31/517 , A61P35/00 , A61P35/02 , A61P17/00 , A61K31/5377 , A61K31/5415 , A61K31/55 , A61K31/553 , A61K31/635 , A61K31/675 , A61K45/06 , C07D403/12 , C07D405/14 , C07D417/14 , C07D471/04 , C07F9/6521
CPC分类号： C07D471/04 , A61K31/53 , A61K31/5377 , A61K31/5415 , A61K31/55 , A61K31/553 , A61K31/635 , A61K31/675 , A61K45/06 , C07D251/18 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07F9/6521 , C07F9/65583
摘要： Compounds and compositions useful for treating disorders related to KIT and PDFGR are described herein.
摘要翻译：本文描述了可用于治疗与KIT和PDFGR相关的疾病的化合物和组合物。

4. 发明授权

US08528731B2 Labels, related pads thereof, and related methods 有权
标题翻译：标签，相关垫片及相关方法
公开(公告)号：US08528731B2
公开(公告)日：2013-09-10
申请号：US12831245
申请日：2010-07-06
申请人： Adam Bratter , Douglas Wilson , Debbie Caton , Tracey Glenn , Peggy Diaz
发明人： Adam Bratter , Douglas Wilson , Debbie Caton , Tracey Glenn , Peggy Diaz
IPC分类号： G09F3/08
CPC分类号： B42D1/00 , B32B37/02 , B32B37/1292 , B32B38/0004 , B32B38/145 , B32B2038/047 , B32B2307/718 , B32B2309/105 , B32B2519/00 , G09F3/0288 , G09F2003/0222 , G09F2003/0226 , G09F2003/0267
摘要： A label is provided that includes a body portion having an area, a front surface, and a back surface. The label also includes a tab portion having an area and a back surface, and the tab portion is integrally coupled to the body portion and extending from an end of the body portion. A line of weakness divides the tab portion and the body portion, and the line of weakness is formed such that the tab portion is selectively separable from the body portion along the line of weakness. A layer of adhesive is provided on the back surface of the body portion of the label, and a majority of the back surface of the tab portion is free of adhesive. The area of the tab portion is less than the area of the body portion.
摘要翻译：提供一种标签，其包括具有区域，前表面和后表面的主体部分。标签还包括具有区域和后表面的突片部分，并且突片部分一体地联接到主体部分并且从主体部分的端部延伸。弱线将突片部分和主体部分分开，并且形成弱线，使得突片部分可沿着弱线选择性地与主体部分分离。在标签的主体部分的后表面上设置一层粘合剂，并且片状部分的大部分后表面没有粘合剂。突片部分的面积小于主体部分的面积。

5. 外观设计

USD676484S1 Pad of labels 有权
公开(公告)号：USD676484S1
公开(公告)日：2013-02-19
申请号：US29408528
申请日：2011-12-13
申请人： Adam Bratter , Douglas Wilson , Debbie Caton , Tracey Glenn , Peggy Diaz
设计人： Adam Bratter , Douglas Wilson , Debbie Caton , Tracey Glenn , Peggy Diaz

6. 发明申请

US20120232820A1 GRID OSCILLATION ANALYSIS METHOD AND APPARATUS THEREFOR 有权
标题翻译：网格振荡分析方法及其设备
公开(公告)号：US20120232820A1
公开(公告)日：2012-09-13
申请号：US13505118
申请日：2010-11-18
申请人： Douglas Wilson
发明人： Douglas Wilson
IPC分类号： G06F19/00 , G01R25/00 , H02J3/24
CPC分类号： H02J3/24 , Y02E60/728 , Y04S10/265
摘要： A method for determining the contribution of a grid subsystem (12) to oscillations in grid frequency experienced by an external electrical grid (14) in an electrical power network (10). A measurement of grid frequency is taken in the grid sub-system (12) and/or the external electrical grid (14). The measurement(s) of grid frequency can be used to extract oscillations in grid frequency in the grid subsystem (12) and/or the external electrical grid (14). A measurement of active power is recorded on a transmission line (16c) between the grid subsystem (12) and the external electrical grid (14). The phase relationship between the oscillations in grid frequency and the oscillations in active power allows the contribution of the grid subsystem (2) to oscillations in grid frequency in the external electrical grid (14) to be determined.
摘要翻译：一种用于确定电网子系统（12）对电力网络（10）中的外部电网（14）经历的电网频率振荡的贡献的方法。电网频率的测量在电网子系统（12）和/或外部电网（14）中进行。电网频率的测量可用于提取电网子系统（12）和/或外部电网（14）中电网频率的振荡。在电网子系统（12）和外部电网（14）之间的传输线（16c）上记录有功功率的测量。电网频率振荡与有功功率振荡之间的相位关系允许确定电网子系统（2）对外部电网（14）中电网频率振荡的贡献。

7. 发明申请

US20060233994A1 Mobile device label with negative image feature 失效
标题翻译：具有负图像功能的移动设备标签
公开(公告)号：US20060233994A1
公开(公告)日：2006-10-19
申请号：US11239379
申请日：2005-09-28
申请人： Jerry Hodsdon , Douglas Wilson , Russ Pollman , Keith Newburry
发明人： Jerry Hodsdon , Douglas Wilson , Russ Pollman , Keith Newburry
IPC分类号： B32B33/00
CPC分类号： B32B3/02 , B32B7/04 , B32B7/06 , B32B7/12 , B32B25/04 , B32B25/06 , B32B25/20 , B32B29/002 , B32B2307/4023 , B32B2307/412 , B32B2307/748 , B32B2307/75 , B32B2519/00 , G09F3/0286 , G09F3/10 , Y10T428/14 , Y10T428/1486 , Y10T428/15
摘要： An adhesive label is configured to be wrapped around an apparatus and to outline a predetermined image having first and second components. A first facestock has opposite first and second edges that come into proximity with one another when the label is wrapped around the apparatus. The first edge includes first contours that outline the first component of the predetermined image, and the second edge includes second contours that outline the second component. A multilayer sheet assembly comprises the adhesive label, wherein the first facestock inner surface includes a lined portion that is covered by a release liner, and an unlined portion that is not covered by the release liner. The sheet assembly further comprises a second facestock that covers at least some of the unlined portion of the first facestock inner surface, and is adhered thereto using an adhesive.
摘要翻译：粘合标签被配置为围绕设备缠绕并且勾画具有第一和第二部件的预定图像。第一面板具有相反的第一和第二边缘，当标签缠绕在设备周围时彼此接近。第一边缘包括概述预定图像的第一分量的第一轮廓，并且第二边缘包括轮廓第二分量的第二轮廓。多层片材组件包括粘合标签，其中第一面材内表面包括被隔离衬里覆盖的衬里部分和未被剥离衬垫覆盖的无衬里部分。片材组件还包括覆盖第一面板内表面的至少一些无衬里部分并且使用粘合剂粘附到其上的第二面材。

8. 发明申请

US20050203081A1 Inhibitors of protein tyrosine phosphatase 1B 审中-公开
标题翻译：蛋白酪氨酸磷酸酶1B抑制剂
公开(公告)号：US20050203081A1
公开(公告)日：2005-09-15
申请号：US11064390
申请日：2005-02-23
申请人： Jinbo Lee , Steve Kirincich , Michael Smith , Douglas Wilson , Bruce Follows , Zhao-Kui Wan , Diane Joseph-McCarthy , David Erbe , Yan-Ling Zhang , Weixin Xu , Steve Tam
发明人： Jinbo Lee , Steve Kirincich , Michael Smith , Douglas Wilson , Bruce Follows , Zhao-Kui Wan , Diane Joseph-McCarthy , David Erbe , Yan-Ling Zhang , Weixin Xu , Steve Tam
IPC分类号： A61K31/381 , A61K31/407 , A61K31/4743 , A61K31/55 , C07D333/70 , C07D495/04 , C07D498/02
CPC分类号： C07D495/04 , C07D333/70
摘要： Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted bicyclic fused-thiophene compounds can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.
摘要翻译：蛋白酪氨酸磷酸酶（PTPases）如PTP1B可以在调节各种细胞反应（如胰岛素信号）中发挥作用。取代的双环稠合噻吩化合物可以抑制PTP1B，从而诱导更大的胰岛素敏感性。因此，PTP1B抑制可以为PTPase介导的病症例如糖尿病提供替代治疗。

9. 发明授权

US5320102A Method for diagnosing proteoglycan deficiency in cartilage based on magnetic resonance image (MRI) 失效
标题翻译：基于磁共振图像（MRI）诊断软骨蛋白多糖缺乏的方法
公开(公告)号：US5320102A
公开(公告)日：1994-06-14
申请号：US978511
申请日：1992-11-18
申请人： Pradip K. Paul , Mukundrai K. Jasani , Elizabeth O'Byrne , Douglas Wilson , Ashok Rakhit
发明人： Pradip K. Paul , Mukundrai K. Jasani , Elizabeth O'Byrne , Douglas Wilson , Ashok Rakhit
IPC分类号： A61B5/11 , G01R33/56 , G01R33/563 , A61B5/055
CPC分类号： G01R33/563 , A61B5/11 , A61B5/4514 , A61B5/4528 , G01R33/56
摘要： Proteoglycan deficiency in articular cartilage is diagnosed based on quantified signal intensities of pixels of a magnetic resonance image (MRI) extending across a depth of the articular cartilage. A pattern of the thus quantified signal intensities is indicative of proteoglycan distribution across the cartilage depth.
摘要翻译：基于延伸穿过关节软骨深度的磁共振图像（MRI）的像素的量化信号强度来诊断关节软骨中的蛋白多糖缺陷。如此定量的信号强度的图案表示软骨深度上的蛋白聚糖分布。

10. 发明授权

US4528342A Epoxy resin compositions 失效
标题翻译：环氧树脂组合物
公开(公告)号：US4528342A
公开(公告)日：1985-07-09
申请号：US649285
申请日：1984-09-11
申请人： Douglas Wilson
发明人： Douglas Wilson
IPC分类号： C08G59/00 , C08G59/18 , C08G59/20 , C08G59/40 , C08J5/24 , C08L63/00 , C08G63/00 , C08G69/00
CPC分类号： C08J5/24 , C08L63/00 , C08J2363/00
摘要： A hardenable epoxy resin comprising a curable epoxy resin, a hardener for the epoxy resin and a polymer of epihalohydrin which composition is characterized in that the amount of the polymer of epihalohydrin in the composition is from 1 to 6 parts per one hundred parts by weight of the epoxy resin and in that the composition also comprises from 2 to 25 parts by weight per hundred parts by weight of the epoxy resin, of a polycarbonate having the general formula: ##STR1## where R.sub.1 and R.sub.2 are the same or different and are phenyl or cyclohexyl groups, R.sub.3 and R.sub.4 are the same or different and are hydrogen, methyl or cyclohexyl groups and n is from 60 to 400 and represents the average number of monomer units in the polymer chain.
摘要翻译：包含可固化环氧树脂，环氧树脂用固化剂和表卤代醇聚合物的可硬化环氧树脂，其组合物的特征在于组合物中表卤代醇的聚合物的量为每100份重量的环氧树脂，并且组合物还包含每100重量份环氧树脂2至25重量份的具有以下通式的聚碳酸酯：其中R 1和R 2相同或不同，为苯基或环己基，R 3和R 4相同或不同，为氢，甲基或环己基，n为60至400，表示聚合物链中单体单元的平均数。

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