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1. 发明授权

US07894868B2 Physiological monitor 有权
标题翻译：生理监护仪
公开(公告)号：US07894868B2
公开(公告)日：2011-02-22
申请号：US11429473
申请日：2006-05-05
申请人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
发明人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
IPC分类号： A61B5/1455
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/02416 , A61B5/1459 , A61B5/6814 , A61B5/6815 , A61B5/6819 , A61B5/6825 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/742 , A61B5/746 , A61M16/00 , A61M16/021 , A61M2230/205
摘要： A patient monitor has multiple sensors adapted to attach to tissue sites of a living subject. The sensors generate sensor signals that are responsive to at least two wavelengths of optical radiation after attenuation by pulsatile blood within the tissue sites. A patient monitor uses the signals to determine if there is a heart abnormality.
摘要翻译：患者监护仪具有适于附着于活体的组织部位的多个传感器。传感器产生响应于在组织部位内的脉动血液衰减之后的至少两个波长的光辐射的传感器信号。患者监护仪使用信号来确定是否有心脏异常。

2. 发明授权

US08255028B2 Physiological monitor 有权
标题翻译：生理监护仪
公开(公告)号：US08255028B2
公开(公告)日：2012-08-28
申请号：US11429471
申请日：2006-05-05
申请人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
发明人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
IPC分类号： A61B5/1455
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/02416 , A61B5/1459 , A61B5/6814 , A61B5/6815 , A61B5/6819 , A61B5/6825 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/742 , A61B5/746 , A61M16/00 , A61M16/021 , A61M2230/205
摘要： A patient monitor has multiple sensors adapted to attach to tissue sites of a living subject. The sensors generate sensor signals that are responsive to at least two wavelengths of optical radiation after attenuation by pulsatile blood within the tissue sites. A patient monitor uses the plurality of signals to reduce the effects of noise.
摘要翻译：患者监护仪具有适于附着于活体的组织部位的多个传感器。传感器产生响应于在组织部位内的脉动血液衰减之后的至少两个波长的光辐射的传感器信号。患者监视器使用多个信号来减少噪声的影响。

3. 发明授权

US08364223B2 Physiological monitor 有权
标题翻译：生理监护仪
公开(公告)号：US08364223B2
公开(公告)日：2013-01-29
申请号：US11417931
申请日：2006-05-03
申请人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
发明人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
IPC分类号： A61B5/1455
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/02416 , A61B5/1459 , A61B5/6814 , A61B5/6815 , A61B5/6819 , A61B5/6825 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/742 , A61B5/746 , A61M16/00 , A61M16/021 , A61M2230/205
摘要： A patient monitor has multiple sensors adapted to attach to tissue sites of a living subject. The sensors generate sensor signals that are responsive to at least two wavelengths of optical radiation after attenuation by pulsatile blood within the tissue sites.
摘要翻译：患者监护仪具有适于附着于活体的组织部位的多个传感器。传感器产生响应于在组织部位内的脉动血液衰减之后的至少两个波长的光辐射的传感器信号。

4. 发明授权

US06334065B1 Stereo pulse oximeter 有权
标题翻译：立体声脉搏血氧仪
公开(公告)号：US06334065B1
公开(公告)日：2001-12-25
申请号：US09323176
申请日：1999-05-27
申请人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
发明人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
IPC分类号： A61B500
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/02416 , A61B5/1459 , A61B5/6814 , A61B5/6815 , A61B5/6819 , A61B5/6825 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/742 , A61B5/746 , A61M16/00 , A61M16/021 , A61M2230/205
摘要： An improved pulse oximeter provides for simultaneous, noninvasive oxygen status and photoplethysmograph measurements at both single and multiple sites. In particular, this multiple-site, multiple-parameter pulse oximeter, or “stereo pulse oximeter” simultaneously measures both arterial and venous oxygen saturation at any specific site and generates a corresponding plethysmograph waveform. A corresponding computation of arterial minus venous oxygen saturation is particularly advantageous for oxygen therapy management. An active pulse-inducing mechanism having a scattering-limited drive generates a consistent pulsatile venous signal utilized for the venous blood measurements. The stereo pulse oximeter also measures arterial oxygen saturation and plethysmograph shape parameters across multiple sites. A corresponding calculation of delta arterial saturation and comparison of plethysmograph shape parameters between multiple sites is particularly advantageous for the detection and management of persistent pulmonary hypertension in neonates (PPHN), a patent ductus arteriosis (PDA), and aortic coarctation.
摘要翻译：改进的脉搏血氧饱和度计在单个和多个位置提供同时，无创的氧状态和光谱体积描记测量。特别地，该多位点多参数脉搏血氧计或“立体声脉搏血氧计”同时测量任何特定部位的动脉和静脉血氧饱和度，并产生相应的体积描记器波形。动脉负静脉血氧饱和度的相应计算对于氧疗治疗特别有利。具有散射限制驱动的主动脉冲诱导机构产生用于静脉血液测量的一致的脉动静脉信号。立体声脉搏血氧饱和度计还可测量多个部位的动脉血氧饱和度和体积描记图形状参数。对于新生儿持续性肺动脉高压（PPHN），动脉导管未闭（PDA）和主动脉缩窄的检测和治疗，三位动脉饱和度的相应计算和多个位置之间体积描记图形状参数的比较特别有利。

5. 发明授权

US07899507B2 Physiological monitor 有权
标题翻译：生理监护仪
公开(公告)号：US07899507B2
公开(公告)日：2011-03-01
申请号：US11417545
申请日：2006-05-03
申请人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
发明人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
IPC分类号： A61B5/1455
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/02416 , A61B5/1459 , A61B5/6814 , A61B5/6815 , A61B5/6819 , A61B5/6825 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/742 , A61B5/746 , A61M16/00 , A61M16/021 , A61M2230/205
摘要： A patient monitor has multiple sensors adapted to attach to tissue sites of a living subject. The sensors generate sensor signals that are responsive to at least two wavelengths of optical radiation after attenuation by pulsatile blood within the tissue sites. Multiple data channels and associated quality parameters are derived from the sensor signals. A processor is configured to operate on the channels according to the quality parameters so as to provide a robust oxygen status measurement.
摘要翻译：患者监护仪具有适于附着于活体的组织部位的多个传感器。传感器产生响应于在组织部位内的脉动血液衰减之后的至少两个波长的光辐射的传感器信号。从传感器信号导出多个数据信道和相关联的质量参数。处理器被配置为根据质量参数在通道上操作，以便提供稳健的氧气状态测量。

6. 发明授权

US07891355B2 Physiological monitor 有权
标题翻译：生理监护仪
公开(公告)号：US07891355B2
公开(公告)日：2011-02-22
申请号：US11417661
申请日：2006-05-03
申请人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
发明人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
IPC分类号： F16K31/02 , A61B5/1455
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/02416 , A61B5/1459 , A61B5/6814 , A61B5/6815 , A61B5/6819 , A61B5/6825 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/742 , A61B5/746 , A61M16/00 , A61M16/021 , A61M2230/205
摘要： A patient monitor has multiple sensors adapted to attach to tissue sites of a living subject. The sensors generate sensor signals that are responsive to at least two wavelengths of optical radiation after attenuation by pulsatile blood within the tissue sites. A patient monitor uses the sensor signals to determine changes in constant oxygen consumption as an indication of changes in metabolism at the tissue cite.
摘要翻译：患者监护仪具有适于附着于活体的组织部位的多个传感器。传感器产生响应于在组织部位内的脉动血液衰减之后的至少两个波长的光辐射的传感器信号。患者监护仪使用传感器信号来确定恒定氧气消耗的变化，作为组织引诱代谢变化的指标。

7. 发明授权

US07761128B2 Physiological monitor 有权
标题翻译：生理监护仪
公开(公告)号：US07761128B2
公开(公告)日：2010-07-20
申请号：US11104720
申请日：2005-04-13
申请人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
发明人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
IPC分类号： A61B5/145
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/02416 , A61B5/1459 , A61B5/6814 , A61B5/6815 , A61B5/6819 , A61B5/6825 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/742 , A61B5/746 , A61M16/00 , A61M16/021 , A61M2230/205
摘要： A physiological monitor varies perfusion at a tissue site and measures resulting perfusion values and corresponding oxygen consumption values. A constant oxygen consumption relationship between the perfusion values and the oxygen consumption values is characterized, and changes in that relationship are monitored so as to indicate changes in metabolism at the tissue site.
摘要翻译：生理监测器改变组织部位的灌注并测量所得到的灌注值和相应的氧消耗值。表征灌注值和氧气消耗值之间的恒定氧消耗关系，并监测该关系的变化，以指示组织部位的代谢变化。

8. 发明授权

US06898452B2 Stereo pulse oximeter 有权
公开(公告)号：US06898452B2
公开(公告)日：2005-05-24
申请号：US10668487
申请日：2003-09-22
申请人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
发明人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
IPC分类号： A61B5/145 , A61B5/00 , A61B5/024 , A61B5/1455 , A61M16/00
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/02416 , A61B5/1459 , A61B5/6814 , A61B5/6815 , A61B5/6819 , A61B5/6825 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/742 , A61B5/746 , A61M16/00 , A61M16/021 , A61M2230/205
摘要： An improved pulse oximeter provides for simultaneous, noninvasive oxygen status and photoplethysmograph measurements at both single and multiple sites. In particular, this multiple-site, multiple-parameter pulse oximeter, or “stereo pulse oximeter” simultaneously measures both arterial and venous oxygen saturation at any specific site and generates a corresponding plethysmograph waveform. A corresponding computation of arterial minus venous oxygen saturation is particularly advantageous for oxygen therapy management. An active pulse-inducing mechanism having a scattering-limited drive generates a consistent pulsatile venous signal utilized for the venous blood measurements. The stereo pulse oximeter also measures arterial oxygen saturation and plethysmograph shape parameters across multiple sites. A corresponding calculation of delta arterial saturation and comparison of plethysmograph shape parameters between multiple sites is particularly advantageous for the detection and management of persistent pulmonary hypertension in neonates (PPHN), a patent ductus arteriosis (PDA), and aortic coarctation.

9. 发明授权

US06714804B2 Stereo pulse oximeter 有权
标题翻译：立体声脉搏血氧仪
公开(公告)号：US06714804B2
公开(公告)日：2004-03-30
申请号：US10026013
申请日：2001-12-21
申请人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
发明人： Ammar Al-Ali , Mohamed K. Diab , Massi E. Kiani , Robert James Kopotic , David Tobler
IPC分类号： A61B500
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/02416 , A61B5/1459 , A61B5/6814 , A61B5/6815 , A61B5/6819 , A61B5/6825 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/742 , A61B5/746 , A61M16/00 , A61M16/021 , A61M2230/205
摘要： An improved pulse oximeter provides for simultaneous, noninvasive oxygen status and photoplethysmograph measurements at both single and multiple sites. In particular, this multiple-site, multiple-parameter pulse oximeter, or “stereo pulse oximeter” simultaneously measures both arterial and venous oxygen saturation at any specific site and generates a corresponding plethysmograph waveform. A corresponding computation of arterial minus venous oxygen saturation is particularly advantageous for oxygen therapy management. An active pulse-inducing mechanism having a scattering-limited drive generates a consistent pulsatile venous signal utilized for the venous blood measurements. The stereo pulse oximeter also measures arterial oxygen saturation and plethysmograph shape parameters across multiple sites. A corresponding calculation of delta arterial saturation and comparison of plethysmograph shape parameters between multiple sites is particularly advantageous for the detection and management of persistent pulmonary hypertension in neonates (PPHN), a patent ductus arteriosis (PDA), and aortic coarctation.
摘要翻译：改进的脉搏血氧饱和度计在单个和多个位置提供同时，无创的氧状态和光谱体积描记测量。特别地，该多位点多参数脉搏血氧计或“立体声脉搏血氧计”同时测量任何特定部位的动脉和静脉血氧饱和度，并产生相应的体积描记器波形。动脉负静脉血氧饱和度的相应计算对于氧疗治疗特别有利。具有散射限制驱动的主动脉冲诱导机构产生用于静脉血液测量的一致的脉动静脉信号。立体声脉搏血氧饱和度计还可测量多个部位的动脉血氧饱和度和体积描记图形状参数。对于新生儿持续性肺动脉高压（PPHN），动脉导管未闭（PDA）和主动脉缩窄的检测和治疗，三位动脉饱和度的相应计算和多个位置之间体积描记图形状参数的比较特别有利。

10. 发明授权

US07530949B2 Dual-mode pulse oximeter 有权
标题翻译：双模脉搏血氧仪
公开(公告)号：US07530949B2
公开(公告)日：2009-05-12
申请号：US10911391
申请日：2004-08-03
申请人： Ammar Al Ali , Don Carothers , David Dalke , Mohamed K. Diab , Julian Goldman , Massi E. Kiani , Michael Lee , Jerome Novak , Robert Smith , Val E. Vaden
发明人： Ammar Al Ali , Don Carothers , David Dalke , Mohamed K. Diab , Julian Goldman , Massi E. Kiani , Michael Lee , Jerome Novak , Robert Smith , Val E. Vaden
IPC分类号： A61B5/00
CPC分类号： A61B5/14551 , A61B5/0002 , A61B5/1495 , A61B5/742 , A61B2560/0271 , A61B2560/0456 , A61B2562/085 , G06F19/00
摘要： A pulse oximeter has an integrated mode in which it operates as a plug-in module for a multiparameter patient monitoring system (MPMS). The pulse oximeter also has a portable mode in which operates separately from the MPMS as a battery-powered handheld or standalone instrument. The pulse oximeter has a sensor port that receives a photo-plethysmographic signal as input to an internal processor. The pulse oximeter processes this sensor signal to derive oxygen saturation and pulse rate measurements. In the portable mode, this information is provided on its display, and stored in memory for trend capability. In the integrated mode, the pulse oximeter provides oxygen saturation and pulse rate measurements to the MPMS through a docking station to be displayed on a MPMS monitor. In the integrated mode, the portable pulse oximeter docks to the docking station, which in turn is inserted in one or more MPMS slots. The docking station can function as a simple electrical pass-through device between the docked portable pulse oximeter and the MPMS or it can provide a MPMS communications interface.
摘要翻译：脉搏血氧计具有集成模式，其作为用于多参数病人监测系统（MPMS）的插件模块。脉搏血氧计还具有便携式模式，其中与MPMS分开操作，作为电池供电的手持或独立仪器。脉搏血氧计具有传感器端口，其接收作为对内部处理器的输入的光学体积描记信号。脉冲血氧计处理该传感器信号以导出氧饱和度和脉搏率测量。在便携式模式中，该信息在其显示器上提供，并存储在存储器中用于趋势能力。在集成模式中，脉搏血氧计通过对接站向MPMS提供氧饱和度和脉搏率测量，以在MPMS监视器上显示。在集成模式中，便携式脉搏血氧仪停靠在对接站，对接站又插入一个或多个MPMS槽中。对接站可以作为对接便携式脉搏血氧计与MPMS之间的简单电气穿越装置，或者可以提供MPMS通信接口。

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