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1. 发明申请

US20110046725A1 METHOD OF IMAGING FOR HEART VALVE IMPLANT PROCEDURE 失效
标题翻译：心瓣植入手术成像方法
公开(公告)号：US20110046725A1
公开(公告)日：2011-02-24
申请号：US12545435
申请日：2009-08-21
申请人： Alois Noettling , Jan Boese , Matthias John , Volkmar Falk , Thomas Walther
发明人： Alois Noettling , Jan Boese , Matthias John , Volkmar Falk , Thomas Walther
IPC分类号： A61F2/24 , A61B6/03 , A61B6/00 , G01N23/04 , H05G1/60 , G06K9/00 , G09G5/00
CPC分类号： A61B6/032 , A61B6/503 , A61B8/0883 , A61F2/24
摘要： A method as a workflow for imaging for a heart valve implant procedure includes positioning the patient and an articulated imaging apparatus relative to one another, inducing rapid ventricular pacing in the patient, and imaging a region of the patient's heart to obtain image date for a three-dimensional image. The three-dimensional data is used to construct a three-dimensional image of the region of the patient's heart an the three-dimensional image is displayed for use in the implanting of the replacement heart valve. Optional steps may include obtaining a real time two-dimensional image of the patient's heart and superimposing the real time two-dimensional image with the constructed three dimensional image. The replacement valve is moved into position in the patient's heart during rapid ventricular pacing and breath hold using the superimposed two-dimensional and three-dimensional image information.
摘要翻译：作为用于心脏瓣膜植入程序的成像工作流程的方法包括相对于彼此定位患者和关节成像装置，在患者体内引起快速心室起搏，以及对患者心脏的区域进行成像以获得三维图像的图像日期维度图像。三维数据用于构建患者心脏区域的三维图像，显示三维图像以用于置换心脏瓣膜的植入。可选步骤可以包括获得患者心脏的实时二维图像，并且用构建的三维图像叠加实时二维图像。使用重叠的二维和三维图像信息，在快速心室起搏和呼吸保持期间将置换瓣膜移动到患者心脏中的位置。

2. 发明授权

US08177835B2 Method of imaging for heart valve implant procedure 失效
标题翻译：心脏瓣膜植入术成像方法
公开(公告)号：US08177835B2
公开(公告)日：2012-05-15
申请号：US12545435
申请日：2009-08-21
申请人： Alois Noettling , Jan Boese , Matthias John , Volkmar Falk , Thomas Walther
发明人： Alois Noettling , Jan Boese , Matthias John , Volkmar Falk , Thomas Walther
IPC分类号： A61F2/24 , A61B5/05
CPC分类号： A61B6/032 , A61B6/503 , A61B8/0883 , A61F2/24
摘要： A method as a workflow for imaging for a heart valve implant procedure includes positioning the patient and an articulated imaging apparatus relative to one another, inducing rapid ventricular pacing in the patient, and imaging a region of the patient's heart to obtain image date for a three-dimensional image. The three-dimensional data is used to construct a three-dimensional image of the region of the patient's heart an the three-dimensional image is displayed for use in the implanting of the replacement heart valve. Optional steps may include obtaining a real time two-dimensional image of the patient's heart and superimposing the real time two-dimensional image with the constructed three dimensional image. The replacement valve is moved into position in the patient's heart during rapid ventricular pacing and breath hold using the superimposed two-dimensional and three-dimensional image information.
摘要翻译：作为用于心脏瓣膜植入程序的成像工作流程的方法包括相对于彼此定位患者和关节成像装置，在患者体内引起快速心室起搏，以及对患者心脏的区域进行成像以获得三维图像的图像日期维度图像。三维数据用于构建患者心脏区域的三维图像，显示三维图像以用于置换心脏瓣膜的植入。可选步骤可以包括获得患者心脏的实时二维图像，并且用构建的三维图像叠加实时二维图像。使用重叠的二维和三维图像信息，在快速心室起搏和呼吸保持期间将置换瓣膜移动到患者心脏中的位置。

3. 发明申请

US20110052026A1 Method and Apparatus for Determining Angulation of C-Arm Image Acquisition System for Aortic Valve Implantation 审中-公开
标题翻译：用于确定主动脉瓣植入的C臂图像采集系统的角度的方法和装置
公开(公告)号：US20110052026A1
公开(公告)日：2011-03-03
申请号：US12858494
申请日：2010-08-18
申请人： Rui Liao , Yefeng Zheng , Matthias John , Alois Noettling , Jan Boese
发明人： Rui Liao , Yefeng Zheng , Matthias John , Alois Noettling , Jan Boese
IPC分类号： G06K9/00
CPC分类号： G06T7/73 , G06T2207/10116 , G06T2207/30052 , G06T2207/30101
摘要： A method and system for determining an angulation of a C-arm image acquisition system for aortic valve implantation is disclosed. One or more landmarks of the aortic root is detected in a 3D image. A plane representing an aortic annulus direction is defined in the 3D image based on the detected anatomic landmarks. A viewing angle is determined that is perpendicular to the defined plane.
摘要翻译：公开了一种用于确定用于主动脉瓣植入的C臂图像采集系统的角度的方法和系统。在3D图像中检测到主动脉根部的一个或多个标记。基于检测到的解剖标志，在3D图像中定义代表主动脉环带方向的平面。确定垂直于限定平面的视角。

4. 发明授权

US09014423B2 Method and system for catheter tracking in fluoroscopic images using adaptive discriminant learning and measurement fusion 有权
标题翻译：使用自适应判别学习和测量融合的荧光镜图像中导管跟踪的方法和系统
公开(公告)号：US09014423B2
公开(公告)日：2015-04-21
申请号：US13412882
申请日：2012-03-06
申请人： Peng Wang , Yefeng Zheng , Matthias John , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
发明人： Peng Wang , Yefeng Zheng , Matthias John , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
IPC分类号： G06K9/00 , A61B6/00 , A61B6/12 , G06T7/20
CPC分类号： A61B6/487 , A61B6/12 , A61B6/503 , G06T7/246 , G06T2207/10016 , G06T2207/10064 , G06T2207/20076 , G06T2207/20081 , G06T2207/30021 , G06T2207/30048
摘要： A method and system for adaptive discriminant learning and measurement fusion for image based catheter tracking is disclosed. An adaptive discriminant model is trained online based on a tracked object, such as a pigtail catheter tip, in at least one previous frame of a fluoroscopic image sequence. The object is tracked in the current frame of the fluoroscopic image sequence based at least on the adaptive discriminant model trained online. The object may be tracked in the current frame based on a fusion of three types of measurement models including the adaptive discriminant model trained online, an object detection model trained offline, and an online appearance model.
摘要翻译：公开了一种用于基于图像的导管跟踪的自适应判别学习和测量融合的方法和系统。在荧光镜像图像序列的至少一个先前帧中，基于跟踪对象（例如尾纤导管尖端）在线训练自适应判别模型。至少基于在线训练的自适应判别模型，在透视图像序列的当前帧中跟踪对象。基于三种类型的测量模型的融合，可以在当前帧中跟踪对象，包括在线训练的自适应判别模型，离线训练的对象检测模型和在线外观模型。

5. 发明申请

US20120296202A1 Method and System for Registration of Ultrasound and Physiological Models to X-ray Fluoroscopic Images 有权
标题翻译：超声和生理模型注射X射线荧光镜图像的方法和系统
公开(公告)号：US20120296202A1
公开(公告)日：2012-11-22
申请号：US13475048
申请日：2012-05-18
申请人： Peter Mountney , Markus Kaiser , Ingmar Voigt , Matthias John , Razvan Ioan Ionasec , Jan Boese , Dorin Comaniciu
发明人： Peter Mountney , Markus Kaiser , Ingmar Voigt , Matthias John , Razvan Ioan Ionasec , Jan Boese , Dorin Comaniciu
IPC分类号： A61B6/02 , A61B8/12
CPC分类号： A61B6/12 , A61B6/4417 , A61B6/4441 , A61B6/487 , A61B6/503 , A61B6/5247 , A61B8/0841 , A61B8/0883 , A61B8/12 , A61B8/4245 , A61B8/4416 , A61B8/5261
摘要： A method and system for registering ultrasound images and physiological models to x-ray fluoroscopy images is disclosed. A fluoroscopic image and an ultrasound image, such as a Transesophageal Echocardiography (TEE) image, are received. A 2D location of an ultrasound probe is detected in the fluoroscopic image. A 3D pose of the ultrasound probe is estimated based on the detected 2D location of the ultrasound probe in the fluoroscopic image. The ultrasound image is mapped to a 3D coordinate system of a fluoroscopic image acquisition device used to acquire the fluoroscopic image based on the estimated 3D pose of the ultrasound probe. The ultrasound image can then be projected into the fluoroscopic image using a projection matrix associated with the fluoroscopic image. A patient specific physiological model can be detected in the ultrasound image and projected into the fluoroscopic image.
摘要翻译：公开了一种用于将超声图像和生理模型记录到X射线透视图像的方法和系统。接收透视图像和超声图像，如经食道超声心动图（TEE）图像。在透视图像中检测超声探头的2D位置。基于在荧光镜图像中检测到的超声波探头的2D位置来估计超声探头的3D姿态。超声图像被映射到用于根据超声探头的估计3D姿势获取荧光镜图像的荧光镜图像采集装置的3D坐标系。然后可以使用与透视图像相关联的投影矩阵将超声图像投影到透视图像中。可以在超声图像中检测患者特异性生理模型并将其投影到透视图像中。

6. 发明申请

US20120123250A1 Method and System for Pigtail Catheter Motion Prediction 有权
标题翻译：猪尾导管运动预测方法与系统
公开(公告)号：US20120123250A1
公开(公告)日：2012-05-17
申请号：US13297373
申请日：2011-11-16
申请人： Yu Pang , Yefeng Zheng , Matthias John , Jan Boese , Dorin Comaniciu
发明人： Yu Pang , Yefeng Zheng , Matthias John , Jan Boese , Dorin Comaniciu
IPC分类号： A61B6/00
CPC分类号： A61B6/487 , A61B6/12 , A61B6/5264 , G06T7/246 , G06T7/277 , G06T2207/10121 , G06T2207/30021
摘要： A method and system for autoregressive model based pigtail catheter motion prediction in a fluoroscopic image sequence is disclosed. Parameters of an autoregressive model are estimated based on observed pigtail catheter tip positions in a plurality of previous frames of a fluoroscopic image sequence. A pigtail catheter tip position in a current frame of the fluoroscopic image sequence is predicted using the fitted autoregressive model. The predicted pigtail catheter tip position can be used to constrain pigtail catheter tip detection in the current frame. The predicted pigtail catheter tip position may also be used to predict abnormal motion in the fluoroscopic image sequence.
摘要翻译：公开了一种在透视图像序列中基于自回归模型的尾纤导管运动预测的方法和系统。基于在透视图像序列的多个先前帧中的观察到的尾纤导管尖端位置来估计自回归模型的参数。使用拟合的自回归模型预测荧光镜图像序列的当前帧中的尾纤导管尖端位置。预测的猪尾导管尖端位置可用于限制当前帧中的尾纤导管尖端检测。预测的猪尾导管尖端位置也可以用于预测荧光镜像图像序列中的异常运动。

7. 发明申请

US20100104164A1 Method and device for obtaining a volume data set of a mobile tissue or organ of a patient 有权
标题翻译：用于获得患者的移动组织或器官的体积数据集的方法和装置
公开(公告)号：US20100104164A1
公开(公告)日：2010-04-29
申请号：US12518123
申请日：2008-04-04
申请人： Meir Bartal , Jan Boese , Assaf Govari , Matthias John , Assaf Preiss , Norbert Rahn
发明人： Meir Bartal , Jan Boese , Assaf Govari , Matthias John , Assaf Preiss , Norbert Rahn
IPC分类号： G06K9/62
CPC分类号： A61B6/4441 , A61B5/1127 , A61B6/503 , A61B6/583
摘要： A method and a device for obtaining a volume data set of a mobile tissue or organ of a patient by a C-arm X-ray device are provided. An electromagnetic sensor of a position detection system is arranged indirectly on the tissue or organ. The X-ray device obtains a plurality of X-ray projections from the tissue or organ from various projection directions. A first method consists of reconstructing a volume data set from the X-ray projections, in which the electromagnetic sensor adopts a position characterizing a displacement phase of the tissue or organ. A second method consists of reconstructing a volume data set from the X-ray projections captured when the electromagnetic sensor was located in a position characterizing a displacement phase of the tissue or organ. A third method does not capture an X-ray projection for the reconstruction if the electromagnetic sensor is located in a position characterizing a displacement phase.
摘要翻译：提供了一种用于通过C臂X射线装置获得患者的移动组织或器官的体积数据集的方法和装置。位置检测系统的电磁传感器间接地布置在组织或器官上。 X射线装置从各种投影方向从组织或器官获得多个X射线投射。第一种方法包括从X射线投影重建体数据集，其中电磁传感器采用表征组织或器官位移阶段的位置。第二种方法包括当电磁传感器位于表征组织或器官的位移阶段的位置时，从所捕获的X射线投影中重建体数据集。如果电磁传感器位于表征位移相位置的位置，则第三种方法不能捕获用于重建的X射线投影。

8. 发明授权

US09715637B2 Method and system for automatic aorta segmentation 有权
公开(公告)号：US09715637B2
公开(公告)日：2017-07-25
申请号：US12725679
申请日：2010-03-17
申请人： Yefeng Zheng , Bogdan Georgescu , Matthias John , Jan Boese , Dorin Comaniciu
发明人： Yefeng Zheng , Bogdan Georgescu , Matthias John , Jan Boese , Dorin Comaniciu
IPC分类号： G06K9/00 , G06K9/46 , G06T7/12
CPC分类号： G06K9/4638 , G06K2209/051 , G06T7/12 , G06T2200/04 , G06T2207/10081 , G06T2207/30101
摘要： A method and system for aorta segmentation in a 3D volume, such as a C-arm CT volume is disclosed. The aortic root is detected in the 3D volume using marginal space learning (MSL) based segmentation. The aortic arch is detected in the 3D volume using MSL based segmentation. The ascending aorta is tracked from the aortic root to the aortic arch in the 3D volume, and the descending aorta is tracked from the aortic arch in the 3D volume.

9. 发明授权

US08712177B2 Motion compensated overlay 有权
标题翻译：运动补偿叠加
公开(公告)号：US08712177B2
公开(公告)日：2014-04-29
申请号：US13348879
申请日：2012-01-12
申请人： Rui Liao , Yefeng Zheng , Matthias John , Alois Nöttling , Jan Boese
发明人： Rui Liao , Yefeng Zheng , Matthias John , Alois Nöttling , Jan Boese
IPC分类号： G06K9/36
CPC分类号： G06T11/60 , A61B6/032 , A61B6/12 , A61B6/487 , A61B6/5247 , A61B6/5264 , A61B6/541 , A61B8/00 , G06T7/33 , G06T11/00 , G06T2207/10121 , G06T2207/30048 , G06T2207/30101
摘要： A method for displaying a motion compensated overlay includes receiving a model of a structure of interest, capturing an image depicting a region of interest and an instrument, determining whether the structure of interest is visible in the image, registering the model of the structure of interest to the image upon determining that the structure of interest is visible, and combining the model of the structure of interest with the image according to a registration to determine an overlay image.
摘要翻译：用于显示运动补偿覆盖的方法包括接收感兴趣结构的模型，捕获描绘感兴趣区域的图像和仪器，确定感兴趣的结构是否在图像中可见，注册感兴趣结构的模型在确定感兴趣的结构是可见的之后，并且根据注册将感兴趣的结构的模型与图像相结合以确定覆盖图像的图像。

10. 发明授权

US08644576B2 Method and system for multi-part left atrium segmentation in C-arm computed tomography volumes using shape constraints 有权
标题翻译：使用形状约束的C臂计算机断层扫描体积中多部分左心房分割的方法和系统
公开(公告)号：US08644576B2
公开(公告)日：2014-02-04
申请号：US13415890
申请日：2012-03-09
申请人： Yefeng Zheng , Tianzhou Wang , Matthias John , Gareth Funka-Lea , Jan Boese , Dorin Comaniciu
发明人： Yefeng Zheng , Tianzhou Wang , Matthias John , Gareth Funka-Lea , Jan Boese , Dorin Comaniciu
IPC分类号： G06K9/00 , A61B6/00 , A61B5/05
CPC分类号： G06T17/20 , G06T7/12 , G06T7/149 , G06T2200/08 , G06T2207/10081 , G06T2207/20081 , G06T2207/30048 , G06T2210/41
摘要： A method and system for multi-part left atrium (LA) segmentation in a C-arm CT volume is disclosed. Multiple LA part models, including an LA chamber body mesh, an appendage mesh, a left inferior pulmonary vein (PV) mesh, a left superior PV mesh, a right inferior PV mesh, and a right superior PV mesh, are segmented in a 3D volume. The LA chamber body mesh and the appendage mesh may be segmented as a combined object and the PV meshes may be segmented subject to a statistical shape constraint. A consolidated LA mesh is generated from the segmented LA part models.
摘要翻译：公开了一种用于C臂CT体积中多部分左心房（LA）分割的方法和系统。多个LA部分模型，包括LA室体网，附属网，左下肺静脉（PV）网，左上PV网，右下PV网和右上PV网被分割成3D 卷。 LA室体网格和附属网格可以被分割为组合对象，并且PV网格可以被划分为受统计形状约束。从分段的LA零件模型生成合并的LA网格。

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