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1. 发明申请

US20130281911A1 ANCHORED NON-PIERCING DUODENAL SLEEVE AND DELIVERY SYSTEMS 审中-公开
标题翻译：锚定式非连接套管和输送系统
公开(公告)号：US20130281911A1
公开(公告)日：2013-10-24
申请号：US13921082
申请日：2013-06-18
申请人： Allergan, Inc.
发明人： Mitchell H. Babkes , Zachary P. Dominguez , Christopher S. Mudd
IPC分类号： A61F5/00
CPC分类号： A61F5/0079 , A61F5/0076
摘要： An intragastric implant for obesity treatment is disclosed. The device delays digestion by providing a duodenal sleeve, and may also slows gastric emptying by limiting flow through the pyloric sphincter. The implant includes an elongated axially-compressible duodenal sleeve having a non-tissue-piercing anchor on a proximal end sized to lodge within the duodenal bulb. The anchor may have oppositely-directed anchoring flanges to resists migration in both directions. The sleeve may also have barbed ribs to resist proximal movement back up into the stomach. A method of implant includes collapsing/compressing the device and transorally advancing it through the esophagus to be deployed within the duodenum. A dissolvable jacket may constrain the implant for delivery and naturally dissolve upon implant. Removal of the implant may occur in the reverse.
摘要翻译：公开了一种用于肥胖症治疗的胃内植入物。该装置通过提供十二指肠套管来延缓消化，并且还可以通过限制通过幽门括约肌的流动来减缓胃排空。植入物包括细长的可轴向压缩的十二指肠套管，其具有在近端上的非组织刺穿锚固件，其大小设置在十二指肠球囊内。锚固件可以具有相反方向的锚固凸缘以抵抗两个方向上的迁移。套筒还可以具有倒钩肋，以抵抗近端移动回到胃中。一种植入物的方法包括塌缩/压缩装置，并将其经过食道通过其前端部署在十二指肠内。可溶解的护套可以限制植入物用于递送，并且在植入时自然地溶解。相反，可能会发生植入物的移除。

2. 发明申请

US20140350517A1 INJECTION DEVICE WITH STRESS PROTECTION 审中-公开
标题翻译：具有应力保护的注射装置
公开(公告)号：US20140350517A1
公开(公告)日：2014-11-27
申请号：US14284268
申请日：2014-05-21
申请人： Allergan, Inc.
发明人： Zachary P. Dominguez , Tiago Bertolote , Ethan Franklin , Justin J. Schwab , Mike Augarten , Jason Metzner
IPC分类号： A61M5/315 , A61M5/50
CPC分类号： A61M5/31566 , A61M5/31501 , A61M5/486 , A61M5/5086 , A61M2005/3125 , A61M2005/3128 , A61M2005/31508 , A61M2005/3151 , A61M2205/3331 , A61M2205/583
摘要： Described are devices and systems for protection of injectable substances such as adipose cells from excessive stress or pressure during injection procedures. Further described are stress control mechanisms for detecting and/or controlling stress or pressure within injection devices.
摘要翻译：描述了用于在注射过程中保护可注射物质例如脂肪细胞免受过度压力或压力的装置和系统。进一步描述了用于检测和/或控制注射装置内的应力或压力的应力控制机构。

3. 发明申请

US20160114101A1 INJECTION DEVICE AND METHOD FOR DILUTING AN INJECTABLE FLUID 审中-公开
公开(公告)号：US20160114101A1
公开(公告)日：2016-04-28
申请号：US14990694
申请日：2016-01-07
申请人： Allergan, Inc.
发明人： Christopher S. Mudd , Mitchell H. Babkes , Zachary P. Dominguez , Michael J. Prichard , Martha E. Llewellyn , Shaohui Qiu , Lee F. Powers , Brett R. Johnson
IPC分类号： A61M5/14 , A61M5/19 , A61M5/172
CPC分类号： A61M5/1407 , A61M5/172 , A61M5/19 , A61M5/2448 , A61M5/284 , A61M2205/33 , A61M2205/50
摘要： An injection device enables a user to control the dilution ratio of mixed injectable fluid. In one embodiment, the injection device includes a drive unit configured to apply extrusion forces to fluids. In one embodiment, the injection device produces the mixed injectable fluid based on a selected dilution ratio. In one embodiment, the injection device produces the mixed injectable fluid based on selected injection rates.

4. 发明申请

US20140228805A1 MODULAR INJECTION SYSTEM AND METHOD FOR DILUTING AN INJECTABLE FLUID 审中-公开
标题翻译：模块化注射系统和喷射注射液的方法
公开(公告)号：US20140228805A1
公开(公告)日：2014-08-14
申请号：US14253303
申请日：2014-04-15
申请人： Allergan, Inc.
发明人： Christopher S. Mudd , Mitchell H. Babkes , Zachary P. Dominguez , Michael J. Prichard , Martha E. Llewellyn , Shaohui Qiu , Lee F. Powers , Brett R. Johnson , Ahmet Tezel , Corey Josenhans
IPC分类号： A61M5/14 , A61M5/172 , A61M5/142
CPC分类号： A61M5/1408 , A61M5/14244 , A61M5/1452 , A61M5/14526 , A61M5/16827 , A61M5/172 , A61M5/19 , A61M2209/088
摘要： A modular injection system enables a user to control the dilution ratio of mixed injectable fluid. In one embodiment, modular injection system includes a handheld injection device operatively connected to a separate control device. In one embodiment, the control device includes a drive unit configured to apply extrusion forces to fluids. In another embodiment, the handheld injection device includes the drive unit. In one embodiment, the modular injection system produces the mixed injectable fluid based on a selected dilution ratio. In one embodiment, the modular injection system produces the mixed injectable fluid based on selected injection rates.
摘要翻译：模块化注射系统使得用户能够控制混合可注射流体的稀释比。在一个实施例中，模块化注射系统包括可操作地连接到单独的控制装置的手持式注射装置。在一个实施例中，控制装置包括构造成将挤压力施加到流体的驱动单元。在另一个实施例中，手持式注射装置包括驱动单元。在一个实施例中，模块化注射系统基于所选择的稀释比产生混合的可注射流体。在一个实施例中，模块化注射系统基于所选择的注射速率产生混合的可注射流体。

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