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1. 发明申请

US20130030315A1 DEVICES, SYSTEMS AND METHODS TO MONITOR AND TREAT HEART FAILURE (HF) 有权
标题翻译：监测和治疗心脏衰竭（HF）的装置，系统和方法
公开(公告)号：US20130030315A1
公开(公告)日：2013-01-31
申请号：US13194700
申请日：2011-07-29
申请人： Allen J. Keel , Kyungmoo Ryu , Stuart Rosenburg
发明人： Allen J. Keel , Kyungmoo Ryu , Stuart Rosenburg
IPC分类号： A61N1/368 , A61B5/0452
CPC分类号： A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0464 , A61N1/3627 , A61N1/3684 , A61N1/3686
摘要： Described herein are implantable systems and devices, and methods for use therewith, that can be used to monitor and treat heart failure (HF). Such implantable systems preferably includes a lead having at least two electrodes implantable in a patient's left ventricular (LV) chamber. A plurality of different sensing vectors are used to obtain a plurality of IEGMs each of which is indicative of an evoked response at a corresponding different region of the LV chamber. For each of the IEGMs, there is a determination of one or more evoked response metrics indicative of a localized cardiac function at the corresponding region of the LV chamber. The evoke response metrics can be, e.g., paced depolarization integral (PDI) and/or maximum upward slope of an R-wave, but are not limited thereto. The patient's HF condition is monitored based on the localized cardiac function at the plurality of different regions of the LV chamber as determined based on the one or more evoked response metrics determined for each of the IEGMs.
摘要翻译：本文描述了可用于监测和治疗心力衰竭（HF）的可植入系统和装置及其使用的方法。这种可植入系统优选地包括具有可植入患者左心室（LV）腔室中的至少两个电极的引线。使用多个不同的感测向量来获得多个IEGM，每个IEGM指示LV室的相应不同区域处的诱发反应。对于每个IEGM，存在一个或多个诱发响应度量的确定，所述诱发响应度量指示LV室的相应区域处的局部心脏功能。唤醒响应度量可以是例如R波的步调去极化积分（PDI）和/或最大上升斜率，但不限于此。基于根据为每个IEGM确定的一个或多个诱发响应度量确定的，基于LV室的多个不同区域处的局部心脏功能来监测患者的HF状况。

2. 发明申请

US20130030314A1 DEVICES, SYSTEMS AND METHODS TO PERFORM ARRHYTHMIA DISCRIMINATION BASED ON THE ATRIAL AND VENTRICULAR ACTIVATION TIMES 有权
标题翻译：基于ATRIAL和VENTRICULAR激活时间进行ARRHYTHMIA诊断的设备，系统和方法
公开(公告)号：US20130030314A1
公开(公告)日：2013-01-31
申请号：US13194747
申请日：2011-07-29
申请人： Allen J. Keel , Kyungmoo Ryu , Stuart Rosenburg
发明人： Allen J. Keel , Kyungmoo Ryu , Stuart Rosenburg
IPC分类号： A61B5/046 , A61N1/368 , A61B5/0464 , A61B5/0452
CPC分类号： A61N1/3962 , A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0464 , A61N1/3627 , A61N1/3684 , A61N1/3686
摘要： Described herein are implantable systems and devices, and methods for use therewith, that can be used to perform arrhythmia discrimination based on activation times. A plurality of different sensing vectors are used to obtain a plurality of IEGMs that collectively enable electrical activations to be detected in the left atrial (LA) chamber, the right atrial (RA) chamber, and at least one ventricular chamber of a patient's heart. For each of a plurality of cardiac cycles, there is a determination, based on the plurality of obtained IEGMs, of an LA activation time, an RA activation time, and a ventricular activation time. Arrhythmia discrimination is then performed based on the determined activation times.
摘要翻译：本文描述的是可植入的系统和装置及其使用的方法，其可用于基于活化时间执行心律失常鉴别。使用多个不同的感测向量来获得多个IEGM，其共同地使得能够在左心房（LA）腔室，右心房（RA）腔室和患者心脏的至少一个心室中检测电激活。对于多个心动周期中的每一个，基于多个获得的IEGM，确定LA激活时间，RA激活时间和心室激活时间。然后基于确定的活化时间进行心律失常鉴别。

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