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1. 发明授权

US07834248B2 Plant seed comprising vernolic acid 有权
标题翻译：含有种子酸的植物种子
公开(公告)号：US07834248B2
公开(公告)日：2010-11-16
申请号：US11699817
申请日：2007-01-30
申请人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
发明人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
IPC分类号： A01H5/00
CPC分类号： C12N9/0071 , C12N9/0004 , C12N15/8247 , C12P7/6409 , C12P7/6427 , C12P7/6472
摘要： The present invention relates generally to novel genetic sequences that encode fatty acid epoxygenase enzymes, in particular fatty acid Δ12-epoxygenase enzymes from plants that are mixed function monooxygenase enzymes. More particularly, the present invention exemplifies cDNA sequences from Crepis spp. and Vernonia galamensis that encode fatty acid Δ12-epoxygenases. The genetic sequences of the present invention provide the means by which fatty acid metabolism may be altered or manipulated in organisms, such as, for example, yeasts, moulds, bacteria, insects, birds, mammals and plants, and more particularly in plants. The invention also extends to genetically modified oil-accumulating organisms transformed with the subject genetic sequences and to the oils derived therefrom. The oils thus produced provide the means for the cost-effective raw materials for use in the efficient production of coatings, resins, glues, plastics, surfactants and lubricants.
摘要翻译：本发明一般涉及从作为混合功能单加氧酶的植物编码脂肪酸环氧化酶，特别是脂肪酸和Dgr 12-环氧化酶的新型遗传序列。更具体地，本发明举例说明了来自Crepis spp的cDNA序列。和Vernonia galamensis编码脂肪酸和Dgr; 12-环氧化酶。本发明的遗传序列提供了在生物体例如酵母，霉菌，细菌，昆虫，鸟类，哺乳动物和植物中，更具体地在植物中可以改变或操纵脂肪酸代谢的方法。本发明还延伸到用受试者遗传序列转化的转基因油积聚生物和由其衍生的油。因此生产的油为用于有效生产涂料，树脂，胶水，塑料，表面活性剂和润滑剂的成本效益好的原材料提供了手段。

2. 发明申请

US20070209092A1 Plant seed comprising vernolic acid 有权
标题翻译：含有种子酸的植物种子
公开(公告)号：US20070209092A1
公开(公告)日：2007-09-06
申请号：US11699817
申请日：2007-01-30
申请人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
发明人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
IPC分类号： A01H5/10
CPC分类号： C12N9/0071 , C12N9/0004 , C12N15/8247 , C12P7/6409 , C12P7/6427 , C12P7/6472
摘要： The present invention relates generally to novel genetic sequences that encode fatty acid epoxygenase enzymes, in particular fatty acid Δ12-epoxygenase enzymes from plants that are mixed function monooxygenase enzymes. More particularly, the present invention exemplifies cDNA sequences from Crepis spp. and Vernonia galamensis that encode fatty acid Δ12-epoxygenases. The genetic sequences of the present invention provide the means by which fatty acid metabolism may be altered or manipulated in organisms, such as, for example, yeasts, moulds, bacteria, insects, birds, mammals and plants, and more particularly in plants. The invention also extends to genetically modified oil-accumulating organisms transformed with the subject genetic sequences and to the oils derived therefrom. The oils thus produced provide the means for the cost-effective raw materials for use in the efficient production of coatings, resins, glues, plastics, surfactants and lubricants.
摘要翻译：本发明一般涉及编码脂肪酸环氧化酶的新型遗传序列，特别是来自作为混合功能单加氧酶的植物的脂肪酸Δ12-环氧化酶。更具体地，本发明举例说明了来自Crepis spp的cDNA序列。和Vernonia galamensis，编码脂肪酸Delta12-环氧化酶。本发明的遗传序列提供了在生物体例如酵母，霉菌，细菌，昆虫，鸟类，哺乳动物和植物中，更具体地在植物中可以改变或操纵脂肪酸代谢的方法。本发明还延伸到用受试者遗传序列转化的转基因油积聚生物和由其衍生的油。因此生产的油为用于有效生产涂料，树脂，胶水，塑料，表面活性剂和润滑剂的成本效益好的原材料提供了手段。

3. 发明授权

US07589253B2 Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism 有权
标题翻译：来自植物的脂肪酸环氧化酶基因，用于修饰脂肪酸代谢
公开(公告)号：US07589253B2
公开(公告)日：2009-09-15
申请号：US09981124
申请日：2001-10-17
申请人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
发明人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
IPC分类号： C12N15/82 , A01H5/00
CPC分类号： C12N9/0071 , C12N9/0004 , C12N15/8247 , C12P7/6409 , C12P7/6427 , C12P7/6472
摘要： The present invention relates generally to novel genetic sequences that encode fatty acid epoxygenase enzymes, in particular fatty acid Δ12-epoxygenase enzymes from plants that are mixed function monooxygenase enzymes. More particularly, the present invention exemplifies cDNA sequences from Crepis spp. and Vernonia galamensis that encode fatty acid Δ12-epoxygenases. The genetic sequences of the present invention provide the means by which fatty acid metabolism may be altered or manipulated in organisms, such as, for example, yeasts, moulds, bacteria, insects, birds, mammals and plants, and more particularly in plants. The invention also extends to genetically modified oil-accumulating organisms transformed with the subject genetic sequences and to the oils derived therefrom. The oils thus produced provide the means for the cost-effective raw materials for use in the efficient production of coatings, resins, glues, plastics, surfactants and lubricants.
摘要翻译：本发明一般涉及编码脂肪酸环氧化酶的新型遗传序列，特别是来自作为混合功能单加氧酶的植物的脂肪酸Delta12-环氧化酶。更具体地，本发明举例说明了来自Crepis spp的cDNA序列。和Vernonia galamensis，编码脂肪酸Delta12-环氧化酶。本发明的遗传序列提供了在生物体例如酵母，霉菌，细菌，昆虫，鸟类，哺乳动物和植物中，更具体地在植物中可以改变或操纵脂肪酸代谢的方法。本发明还延伸到用受试者遗传序列转化的转基因油积聚生物和由其衍生的油。因此生产的油为用于有效生产涂料，树脂，胶水，塑料，表面活性剂和润滑剂的成本效益好的原材料提供了手段。

4. 发明授权

US06329518B1 Plant fatty acid epoxygenase genes and uses therefor 失效
标题翻译：植物脂肪酸环氧化酶基因及其用途
公开(公告)号：US06329518B1
公开(公告)日：2001-12-11
申请号：US09059769
申请日：1998-04-14
申请人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
发明人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
IPC分类号： C12N1582
CPC分类号： C12N9/0071 , C12N9/0004 , C12N15/8247 , C12P7/6409 , C12P7/6463
摘要： The present invention relates generally to novel genetic sequences which encode fatty acid epoxygenase enzymes. In particular, the present invention relates to genetic sequences which encode fatty acid &Dgr;12-epoxygenase enzymes comprising mixed function monooxygenase enzymes. More preferably, the present invention provides cDNA sequences which encode plant fatty acid epoxygenases, in particular the Crepis palaestina &Dgr;12-epoxygenase and homologues, analogues and derivatives thereof. The genetic sequences of the present invention provide the means by which fatty acid metabolism may be altered or manipulated in organisms such as yeasts, moulds, bacteria, insects, birds, mammals and plants, in particular to convert unsaturated fatty acids to epoxygenated fatty acids therein. The invention extends to genetically modified oil-accumulating organisms transformed with the subject genetic sequences and to the oils derived therefrom. The oils thus produced provide the means for the cost-effective raw materials for use in the efficient production of coatings, resins, glues, plastics, surfactants and lubricants, amongst others.
摘要翻译：本发明一般涉及编码脂肪酸环氧化酶的新型遗传序列。特别地，本发明涉及编码包含混合功能单加氧酶的脂肪酸DELTA12-环氧化酶的遗传序列。更优选地，本发明提供编码植物脂肪酸环氧化酶的cDNA序列，特别是Crepis palaestina DELTA12-环氧化酶及其同系物，类似物和衍生物。本发明的遗传序列提供了在诸如酵母，霉菌，细菌，昆虫，鸟类，哺乳动物和植物的生物体中脂肪酸代谢可被改变或操作的手段，特别是将不饱和脂肪酸转化为环氧化脂肪酸。本发明延伸到用受试者遗传序列转化的转基因油积聚生物和由其衍生的油。因此生产的油为用于有效生产涂料，树脂，胶水，塑料，表面活性剂和润滑剂等的成本效益好的原料提供了手段。

5. 发明申请

US20050273885A1 Synthesis of long-chain polyunsaturated fatty acids by recombinant cells 有权
标题翻译：通过重组细胞合成长链多不饱和脂肪酸
公开(公告)号：US20050273885A1
公开(公告)日：2005-12-08
申请号：US11112882
申请日：2005-04-22
申请人： Surinder Singh , Stanley Robert , Peter Nichols , Susan Ellis Blackburn , Xue-Rong Zhou , James Petrie , Allan Green
发明人： Surinder Singh , Stanley Robert , Peter Nichols , Susan Ellis Blackburn , Xue-Rong Zhou , James Petrie , Allan Green
IPC分类号： A01H1/00 , C12N5/04 , C12N9/02 , C12N9/10 , C12N15/82 , C12P7/64
CPC分类号： C12P7/6427 , C07C51/42 , C11B1/025 , C11B1/06 , C11B3/006 , C12N9/0083 , C12N9/1029 , C12N15/8247 , C12P7/6472 , Y02P20/52
摘要： The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain poly unsaturated fatty acids.
摘要翻译：本发明涉及在重组细胞如酵母或植物细胞中合成长链多不饱和脂肪酸，特别是二十碳五烯酸，二十二碳五烯酸和二十二碳六烯酸的方法。还提供了产生长链多不饱和脂肪酸的重组细胞或植物。此外，本发明涉及可用于合成长链多不饱和脂肪酸的方法的一组具有去饱和酶或延伸酶活性的新酶。

6. 发明申请

US20060037104A1 Modified cottonseed oil 有权
公开(公告)号：US20060037104A1
公开(公告)日：2006-02-16
申请号：US11202731
申请日：2005-08-12
申请人： Allan Green , Surinder Singh , Qing Liu
发明人： Allan Green , Surinder Singh , Qing Liu
IPC分类号： A01H1/00 , C12N9/04 , C12N15/82 , C12N15/87
CPC分类号： C12N9/0083 , A01H5/10 , C12N15/8247
摘要： The present invention provides novel gene constructs and methods for the production of transgenic cotton plants that produce oils having a range of desirable attributes, including improved oil quality, and modified fatty acid composition.

7. 发明授权

US06974898B2 Method of modifying the content of cottonseed oil 有权
标题翻译：改变棉籽油含量的方法
公开(公告)号：US06974898B2
公开(公告)日：2005-12-13
申请号：US09837751
申请日：2001-04-18
申请人： Allan Green , Surinder Singh , Qing Liu
发明人： Allan Green , Surinder Singh , Qing Liu
IPC分类号： A01H5/10 , C12N9/02 , C12N15/29 , C12N15/53 , C12N15/82 , A01H5/00
CPC分类号： C12N9/0083 , A01H5/10 , C12N15/8247
摘要： The present invention provides novel gene constructs and methods for the production of transgenic cotton plants that produce oils having a range of desirable attributes, including improved oil quality, and modified fatty acid composition.
摘要翻译：本发明提供了用于生产转基因棉花植物的新型基因构建体和方法，所述转基因棉花植物产生具有所需属性范围的油，包括改良的油质和改良的脂肪酸组成。

8. 发明授权

US07619105B2 Modified cottonseed oil 有权
标题翻译：改性棉籽油
公开(公告)号：US07619105B2
公开(公告)日：2009-11-17
申请号：US11202731
申请日：2005-08-12
申请人： Allan Green , Surinder Singh , Qing Liu
发明人： Allan Green , Surinder Singh , Qing Liu
IPC分类号： A23D9/00
CPC分类号： C12N9/0083 , A01H5/10 , C12N15/8247
摘要： The present invention provides novel gene constructs and methods for the production of transgenic cotton plants that produce oils having a range of desirable attributes, including improved oil quality, and modified fatty acid composition.
摘要翻译：本发明提供了用于生产转基因棉花植物的新型基因构建体和方法，所述转基因棉花植物产生具有所需属性范围的油，包括改良的油质和改良的脂肪酸组成。

9. 发明申请

US20070078082A1 Methods and compositions to treat glycosaminoglycan-associated molecular interactions 审中-公开
标题翻译：治疗糖胺聚糖相关分子相互作用的方法和组合物
公开(公告)号：US20070078082A1
公开(公告)日：2007-04-05
申请号：US11523811
申请日：2006-09-19
申请人： Robert Kisilevsky , Allan Green , Francine Gervais
发明人： Robert Kisilevsky , Allan Green , Francine Gervais
IPC分类号： A61K38/16
CPC分类号： A61K31/472 , A61K31/185 , A61K31/437 , A61K31/737 , Y02A50/478
摘要： Therapeutic compounds and methods for inhibiting a glycosaminoglycan (GAG)-associated molecular interaction in a subject, whatever its clinical setting, are described
摘要翻译：描述了用于抑制受试者中的糖胺聚糖（GAG）相关分子相互作用的治疗化合物和方法，无论其临床情况如何

10. 发明授权

US11124737B2 High oleic acid oils 有权
公开(公告)号：US11124737B2
公开(公告)日：2021-09-21
申请号：US16411697
申请日：2019-05-14
申请人： Craig Christopher Wood , Qing Liu , Xue-Rong Zhou , Allan Green , Surinder Pal Singh , Shijiang Cao
发明人： Craig Christopher Wood , Qing Liu , Xue-Rong Zhou , Allan Green , Surinder Pal Singh , Shijiang Cao
IPC分类号： C12N15/82 , A23D9/00 , C11B1/10 , C12N9/02
摘要： The present invention relates to extracted lipid with high levels, for example 90% to 95% by weight, oleic acid. The present invention also provides genetically modified plants, particularly oilseeds such as safflower, which can used to produce the lipid. Furthermore, provided are methods for genotyping and selecting plants which can be used to produce the lipid.

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