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    • 5. 发明申请
    • Process for concentration of macromolecules
    • 高分子浓缩方法
    • US20060149042A1
    • 2006-07-06
    • US10532998
    • 2003-11-01
    • Konstantin KonstantinovHuong NguyenJens Vogel
    • Konstantin KonstantinovHuong NguyenJens Vogel
    • C07K1/14
    • C07K14/55C07K1/34C07K1/36
    • The invention provides methods for concentrating a macromolecule from a solution comprising the macromolecule and an organic polymer by first subjecting the solution to ultrafiltration to produce a first retentate solution, then adjusting the conductivity of the first retentate solution such that any protein precipitation induced by the organic polymer is essentially prevented to produce a second retentate solution, and then subjecting the second retentate solution to ultrafiltration. In a preferred embodiment, the conductivity is adjusted by diafiltration against water, suitable diluent or buffer. Preferably, the invention pertains to the concentration of solutions of native or recombinant proteins. The invention further pertains preferably to methods for the concentration of cell culture supernatant comprising a product protein and organic polymers of the Pluronic family of block co-polymers, and more preferably comprising Pluronic F-68 block co-polymer.
    • 本发明提供了从包含大分子和有机聚合物的溶液中浓缩高分子的方法,首先使溶液经过超滤以产生第一滞留物溶液,然后调节第一渗余溶液的电导率,使得由有机物诱导的任何蛋白质沉淀 基本上防止聚合物产生第二滞留物溶液,然后使第二滞留物溶液经过超滤。 在优选的实施方案中,通过对水,合适的稀释剂或缓冲液进行渗滤来调节电导率。 优选地,本发明涉及天然或重组蛋白质的溶液的浓度。 本发明还优选地涉及浓缩包含产物蛋白质的细胞培养上清液和Pluronic族嵌段共聚物的有机聚合物,更优选包含Pluronic F-68嵌段共聚物的方法。
    • 7. 发明授权
    • Gas injection system for plasma processing
    • 用于等离子体处理的气体注入系统
    • US6013155A
    • 2000-01-11
    • US885353
    • 1997-06-30
    • Brian McMillinHuong NguyenMichael BarnesTom Ni
    • Brian McMillinHuong NguyenMichael BarnesTom Ni
    • C23C16/50C23C16/44C23C16/455C23C16/507C30B25/10C30B25/14H01J37/32H01L21/205H01L21/302H05H1/00
    • H01J37/3244C23C16/455C23C16/45565C23C16/45572C23C16/45578C23C16/507C30B25/105C30B25/14H01J37/321
    • A plasma processing system for plasma processing of substrates such as semiconductor wafers. The system includes a plasma processing chamber, a substrate support for supporting a substrate within the processing chamber, a dielectric member having an interior surface facing the substrate support, the dielectric member forming a wall of the processing chamber, a gas supply comprising one or more injector tubes extending rectilinearly in the plasma processing chamber and having one or more orifices in a sidewall for supplying gas into the chamber, and an RF energy source such as a planar coil which inductively couples RF energy through the dielectric member and into the chamber to energize the process gas into a plasma state. The gas is supplied through orifices located outside of regions at the distal tip of the injector tubes where electric field lines are concentrated. The arrangement minimizes clogging of the orifices since the orifices are located away from areas where most build-up of process byproducts occur on the injector tube.
    • 用于诸如半导体晶片的衬底等离子体处理的等离子体处理系统。 该系统包括等离子体处理室,用于在处理室内支撑衬底的衬底支撑件,具有面向衬底支撑件的内表面的电介质构件,形成处理室壁的电介质构件,包括一个或多个 喷射器管在等离子体处理室中直线延伸并且在侧壁中具有一个或多个孔以将气体供应到室中;以及RF能量源,例如平面线圈,其通过电介质构件将RF能量感应耦合到腔中以激励 工艺气体进入等离子体状态。 气体通过位于喷射器管的远端的区域外侧的孔提供,其中电场线集中。 该装置使得孔口的堵塞最小化,因为孔口远离喷射器管上发生过程副产物的最多的区域。
    • 10. 发明申请
    • Electrolyte membrane for fuel cell utilizing nano composite
    • 用于利用纳米复合材料的燃料电池的电解质膜
    • US20070077478A1
    • 2007-04-05
    • US11242816
    • 2005-10-03
    • Khe NguyenHuong NguyenTruc Pham
    • Khe NguyenHuong NguyenTruc Pham
    • H01M8/10H01M4/94
    • H01M8/1048H01M4/926H01M8/1011H01M8/1013H01M8/1027H01M8/103Y02E60/522Y02E60/523
    • An electrolyte membrane is disclosed, for use in a fuel cell, and is composed of ionic transporting elements embedded in a polymer matrix. The elements can be carbon products, dye stuffs molecules, organic molecules, inorganic molecules, semiconductors, oxides, or superconductors. The elements carry ionic groups by chemical attachment of physical absorption. The electrolyte membrane can be a homogeneous or inhomogeneous blend of the ionic transporting elements in the polymer matrix. An anode and an opposing cathode are on opposite sides of the membrane. Respective catalysts are on the anode and cathode. A gas diffusion layer contacts the anode and has openings to allow fuel from a fuel source to pass through to the anode, as fuel is consumed at the anode. Another gas diffusion layer contacts the cathode and has openings to allow oxygen to pass through to the cathode. Fuel consumption generates electricity and produces water.
    • 公开了用于燃料电池中的电解质膜,其由嵌入聚合物基体中的离子输送元件组成。 元素可以是碳产物,染料填料分子,有机分子,无机分子,半导体,氧化物或超导体。 元素通过物理吸收的化学附着携带离子基团。 电解质膜可以是聚合物基质中的离子传输元素的均匀或不均匀的共混物。 阳极和相对的阴极在膜的相对侧上。 各种催化剂都在阳极和阴极上。 随着燃料在阳极消耗,气体扩散层接触阳极并具有允许来自燃料源的燃料通过阳极的开口。 另一个气体扩散层接触阴极并具有允许氧气通过阴极的开口。 燃油消耗产生电力并产生水。