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    • 1. 发明授权
    • Ionization apparatus and method for mass spectrometer system
    • 电离装置及质谱仪系统
    • US06707036B2
    • 2004-03-16
    • US10105172
    • 2002-03-21
    • Alexander A. MakarovPavel V. Bondarenko
    • Alexander A. MakarovPavel V. Bondarenko
    • H01J4900
    • H01J49/067H01J49/0418H01J49/164
    • An ionization apparatus for connection to a mass analyzer is provided. The ionization apparatus comprises a sample slide having at least two sample spots containing analytes to be analyzed by a mass analyzer, means for delivering energy to one of the sample spots to release and ionize the analytes to form ions, and an interface connecting the one of the sample spot to the analyzer. The interface comprises a chamber having an orifice in close proximity to the one of the sample spots and defining a first region encompassing the one of the sample spots, and an ion guide disposed in the chamber and leading to the mass analyzer in a second region. Means for sustaining a pressure substantially lower than atmospheric within the first region is provided for capturing the ions while other sample spots are maintained at atmospheric pressure. Means for sustaining a pressure within the second region substantially lower than the pressure within the first region is provided.
    • 提供了一种用于连接到质量分析器的电离装置。 电离装置包括具有至少两个样品点的样品载片,所述样品点含有要由质量分析仪分析的分析物,用于将能量传递到样品点之一以释放和离子化分析物以形成离子的装置,以及将 样品点到分析仪。 所述界面包括具有紧邻所述一个所述样品斑点的孔口并且限定包围所述样品斑点中的一个的第一区域的腔室和设置在所述腔室中并在第二区域中通向所述质量分析器的离子导管。 提供用于在第一区域内维持基本上低于大气压力的装置用于捕获离子,而其它样品斑点保持在大气压。 提供了在第二区域内保持基本上低于第一区域内的压力的装置。