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1. 发明授权

US5730962A Depigmenting cosmetic or dermatologic composition containing a benzofuran derivative and its use in depigmentating skin 失效
标题翻译：含有苯并呋喃衍生物的化妆品或皮肤病学组合物的脱色及其在脱色皮肤中的用途
公开(公告)号：US5730962A
公开(公告)日：1998-03-24
申请号：US914150
申请日：1992-07-16
申请人： Alex Junino , Quang Lan N'Guyen , Remy Tuloup , Christian Blaise
发明人： Alex Junino , Quang Lan N'Guyen , Remy Tuloup , Christian Blaise
IPC分类号： A61K8/00 , A61K8/02 , A61K8/04 , A61K8/06 , A61K8/11 , A61K8/14 , A61K8/49 , A61Q19/00 , A61Q19/02 , C07D307/79 , A61K7/48 , A61K7/00
CPC分类号： A61Q19/02 , A61K8/4973
摘要： A depigmenting cosmetic or dermatologic composition for use in bleaching the skin or treating pigmental spots contains in a vehicle suitable for topical application to the skin a benzofuran derivative having the formula ##STR1## wherein the OH function occupies position 5 or 6, R.sub.1 and R.sub.2, each independently, represent hydrogen or alkyl having 1-4 carbon atoms, n is 0 or 1, when n is 0, the C.sub.2 -C.sub.3 bond is a double bond, and when n is 1, the C.sub.2 -C.sub.3 bond is a single bond.
摘要翻译：用于漂白皮肤或治疗色素斑点的脱色美容品或皮肤病学组合物含有适于局部施用于皮肤的赋形剂，其具有式（I）的苯并呋喃衍生物，其中OH官能占据位置5或6，R1 和R 2各自独立地表示氢或具有1-4个碳原子的烷基，n为0或1，当n为0时，C2-C3键为双键，当n为1时，C2-C3键为单一债券。

2. 发明授权

US5203875A Dyeing composition for keratinous fibers, containing oxidation dye precursors and hydroxybenzofurane used as couplers, and dyeing process using these compositions 失效
标题翻译：用于含有氧化染料前体和用作偶联剂的羟基苯并呋喃的凯氏复合纤维的染色组合物，以及使用这些组合物的染色工艺
公开(公告)号：US5203875A
公开(公告)日：1993-04-20
申请号：US860543
申请日：1992-03-30
申请人： Remy Tuloup , Christian Blaise , Alex Junino
发明人： Remy Tuloup , Christian Blaise , Alex Junino
IPC分类号： A61K8/00 , A61K8/33 , A61K8/34 , A61K8/35 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/49 , A61Q5/10 , C07D307/79 , C07D307/83 , C09B29/22 , D06P1/32 , D06P3/08
CPC分类号： A61K8/4973 , A61Q5/10
摘要： The invention relates to the use, as coupler in a dyeing composition, of a hydroxybenzofuran of formula (I): ##STR1## in which R.sub.1 and R.sub.2, which are identical or different, represent a hydrogen atom or a C.sub.1 -C.sub.6 alkyl radical. When they denote an alkyl radical, R.sub.1 and R.sub.2 can occupy any position on the benzofuran ring except the positions 2 and 3 at the same time. The OH group may occupy one of the positions 4, 5, 6 or 7, in combination with one or more para type or ortho type oxidation dye precursors or mixtures thereof, for dyeing keratinous fibers and in particular human hair. The dyeing composition according to the invention makes it possible to confer on the keratinous fibers a color which is fast to light, washes, adverse weather conditions and perspiration.
摘要翻译：本发明涉及作为染色组合物中的成色剂的式（I）的羟基苯并呋喃的用途：其中R1和R2相同或不同，表示氢原子或C1-C6 烷基。当它们表示烷基时，R1和R2可以同时占据苯并呋喃环上除位置2和3之外的任何位置。 OH基可以占据位置4,5,6或7中的一个，与一种或多种对位型或邻位型氧化染料前体或其混合物组合，用于染色角质纤维，特别是人类头发。根据本发明的染色组合物使得可以赋予角质纤维更快的光，洗涤，不利的天气条件和出汗的颜色。

3. 发明授权

US06514486B1 Composition for topical application comprising at least one iminophenol compound 失效
标题翻译：用于局部施用的组合物，其包含至少一种亚氨基酚化合物
公开(公告)号：US06514486B1
公开(公告)日：2003-02-04
申请号：US09341099
申请日：1999-09-10
申请人： Remy Tuloup , Christian Blaise
发明人： Remy Tuloup , Christian Blaise
IPC分类号： A61K7135
CPC分类号： C07C257/12 , A61K8/40 , A61K8/41 , A61K8/411 , A61K8/44 , A61K8/60 , A61Q5/08 , A61Q19/02
摘要： The invention relates to a composition for topical application to the skin and/or its superficial growths comprising, in a cosmetically and/or dermatologically acceptable medium, at least one compound comprising an iminophenol fragment and to the use of the said compound in a composition as agent for depigmenting and/or lightening the human skin, the body hairs and/or the hair. It also relates to a process for depigmenting and/or lightening the skin, the body hairs and/or the hair which consists in applying the abovementioned composition to the human skin, the body hairs and/or the hair.
摘要翻译：本发明涉及用于局部应用于皮肤和/或其表面生长的组合物，其在美容和/或皮肤病学可接受的培养基中包含至少一种包含亚氨基苯酚片段的化合物和所述化合物在组合物中的用途脱色和/或减轻人体皮肤，身体毛发和/或头发的剂。还涉及一种使皮肤，身体毛发和/或毛发脱色和/或减轻的方法，其中包括将上述组合物对人体皮肤，身体毛发和/或头发。

4. 发明授权

US06423854B1 Aminophenol derivatives and their use in cosmetics 失效
标题翻译：氨基酚衍生物及其在化妆品中的应用
公开(公告)号：US06423854B1
公开(公告)日：2002-07-23
申请号：US09284490
申请日：1999-06-21
申请人： Michel Philippe , Remy Tuloup , Christian Blaise
发明人： Michel Philippe , Remy Tuloup , Christian Blaise
IPC分类号： A61K3156
CPC分类号： C07C271/28 , A61K8/415 , A61Q5/08 , A61Q19/02
摘要： Use of at least one aminophenol derivative of formula (I) below: in which: R represents a hydrogen atom or a radical —COR2, wherein R2 represents a saturated or unsaturated, linear, cyclic or branched, optionally hydroxylated, C1 to C30 hydrocarbon or alkoxy radical; R1 is a radical of formula (a), (b) or (c) below: (a) —CO—NR3R4 (b) —CO—O—R5 (c) —SO2—R5 wherein R3 represents a hydrogen atom or a linear or branched, saturated or unsaturated, optionally hydroxylated, C1 to C6 hydrocarbon radical, R4 represents a hydrogen atom or a saturated or unsaturated, linear, cyclic or branched, optionally hydroxylated, C1 to C30 hydrocarbon radical, and R5 represents a saturated or unsaturated, linear, cyclic or branched, optionally hydroxylated, C1 to C30 hydrocarbon radical, in a depigmenting and/or bleaching cosmetic composition for human skin, body hairs or head hair; compositions comprising the derivatives of formula (I) and a process for depigmenting and/or bleaching the skin, body hairs and/or head hairs.
摘要翻译：至少一种式（I）氨基苯酚衍生物的用途如下：其中：R表示氢原子或-COR2基团，其中R2表示饱和或不饱和的直链，环状或支链的任选羟基化的C 1至C 30烃或烷氧基; R1是下式（a），（b）或（c）的基团：（a）-CO-NR3R4（b）-CO-O-R5（c）-SO2-R5，其中R3表示氢原子或直链或支链，饱和或不饱和的任选羟基化的C 1至C 6烃基，R 4表示氢原子或饱和或不饱和的直链，环状或支链的任选羟基化的C 1至C 30烃基，R 5表示饱和或不饱和的，直链的，环状的或支链的，任选羟基化的C1至C30烃基，用于人皮肤，身体毛发或头发的脱色和/或漂白化妆品组合物; 包含式（I）的衍生物的组合物和用于脱皮和/或漂白皮肤，身体毛发和/或头发的方法。

5. 发明授权

US6010707A Cosmetic and dermatological compositions containing aminoalcohol derivatives containing a urea functional group and uses thereof 失效
标题翻译：包含含有尿素官能团的氨基醇衍生物的化妆品和皮肤病学组合物及其用途
公开(公告)号：US6010707A
公开(公告)日：2000-01-04
申请号：US886457
申请日：1997-07-01
申请人： Michel Philippe , Christian Blaise , Remy Tuloup
发明人： Michel Philippe , Christian Blaise , Remy Tuloup
IPC分类号： A61K8/30 , A61K6/00 , A61K8/00 , A61K8/11 , A61K8/14 , A61K8/40 , A61K8/42 , A61K8/64 , A61K8/89 , A61K8/891 , A61K9/127 , A61Q5/00 , A61Q5/12 , A61Q17/00 , A61Q19/00 , A61K7/48
CPC分类号： A61K8/42 , A61Q19/00 , A61Q17/00 , A61Q19/007 , A61Q5/12 , Y10S514/844 , Y10S514/845 , Y10S514/846 , Y10S514/847 , Y10S514/937 , Y10S514/944
摘要： The invention relates to the use of aminoalcohol derivatives containing a urea functional group corresponding to the following formula: ##STR1## in which: R.sub.1 represents a linear or branched, saturated or unsaturated alkyl radical having from 8 to 22 carbon atoms; R.sub.2 represents a hydrogen atom or a linear or branched, saturated alkyl radical having from 1 to 6 carbon atoms; R.sub.3 represents a linear or branched, monohydroxylated or polyhydroxylated, saturated alkyl group having from 1 to 10 carbon atoms, in and for the preparation of cosmetic or dermatological compositions. These compounds are used in particular as moisturizing agents in care products for the skin or as conditioning agents in hair products.
摘要翻译：本发明涉及含有对应于下式的脲官能团的氨基醇衍生物的用途：其中：R1代表具有8-22个碳原子的直链或支链饱和或不饱和的烷基; R 2表示氢原子或具有1至6个碳原子的直链或支链饱和烷基; R3表示在化妆品或皮肤病学组合物的制备和制备中具有1至10个碳原子的直链或支链，单羟基化或多羟基化的饱和烷基。这些化合物特别用作皮肤护理产品中的保湿剂或作为头发产品中的调理剂。

6. 发明授权

US06924275B2 Aminophenol derivatives and their use in cosmetics 失效
标题翻译：氨基酚衍生物及其在化妆品中的应用
公开(公告)号：US06924275B2
公开(公告)日：2005-08-02
申请号：US10125411
申请日：2002-04-19
申请人： Michel Philippe , Remy Tuloup , Christian Blaise
发明人： Michel Philippe , Remy Tuloup , Christian Blaise
IPC分类号： A61K8/30 , A61K8/00 , A61K8/41 , A61K8/42 , A61K8/46 , A61K31/045 , A61K31/135 , A61K31/17 , A61K31/175 , A61K31/21 , A61K31/27 , A61K31/325 , A61Q5/08 , A61Q19/02 , C07C271/06 , C07C271/28 , C07C275/32 , C07C275/34 , C07J9/00 , A61K31/56
CPC分类号： C07C271/28 , A61K8/415 , A61Q5/08 , A61Q19/02
摘要： Use of at least one aminophenol derivative of formula (I) below: in which: R represents a hydrogen atom or a radical —COR2,wherein R2 represents a saturated or unsaturated, linear, cyclic or branched, optionally hydroxylated, C1 to C30 hydrocarbon or alkoxy radical;R1 is a radical of formula (a), (b) or (c) below:(a) —CO—NR3R4 (b) —CO—O—R5 (c) —SO2—R5 wherein R3 represents a hydrogen atom or a linear or branched, saturated or unsaturated, optionally hydroxylated, C1 to C4 hydrocarbon radical,R4 represents a hydrogen atom or a saturated or unsaturated, linear, cyclic or branched, optionally hydroxylated, C1 to C30 hydrocarbon radical, andR5 represents a saturated or unsaturated, linear, cyclic or branched, optionally hydroxylated, C1 to C30 hydrocarbon radical,in a depigmenting and/or bleaching cosmetic composition for human skin, body hairs or head hair; compositions comprising the derivatives of formula (I) and a process for depigmenting and/or bleaching the skin, body hairs and/or head hairs.
摘要翻译：至少一种式（I）氨基苯酚衍生物的用途如下：其中：R表示氢原子或基团-COR 2，其中R 2表示饱和或不饱和的，直链的，环状的或支链的，任选羟基化的C 1至C 30烃或烷氧基; R 1是下式（a），（b）或（c）的基团：（a）-CO-NR 3 R 4 （b）-CO-OR 5（c）-SO 2 -R 5其中R 3表示氢原子或直链或支链，饱和或不饱和的，任选羟基化的C 1至C 4烃基，R 4代表氢原子或饱和或不饱和的，直链，环状或支链的，任选羟基化的C 1至C 30烃基，R 5表示饱和或不饱和的，直链的，环状的或支链的，任选羟基化的C 1至C 30烃基，在用于人皮肤的脱色和/或漂白化妆品组合物中，身体毛发或头发; 包含式（I）的衍生物的组合物和用于脱皮和/或漂白皮肤，身体毛发和/或头发的方法。

7. 发明授权

US6093412A Cosmetic and dermatological compositions containing aminoalcohol derivatives containing a urea functional group and uses thereof 失效
公开(公告)号：US6093412A
公开(公告)日：2000-07-25
申请号：US357215
申请日：1999-07-20
申请人： Michel Philippe , Christian Blaise , Remy Tuloup
发明人： Michel Philippe , Christian Blaise , Remy Tuloup
IPC分类号： A61K8/30 , A61K6/00 , A61K8/00 , A61K8/11 , A61K8/14 , A61K8/40 , A61K8/42 , A61K8/64 , A61K8/89 , A61K8/891 , A61K9/127 , A61Q5/00 , A61Q5/12 , A61Q17/00 , A61Q19/00 , A61K7/48
CPC分类号： A61K8/42 , A61Q19/00 , A61Q17/00 , A61Q19/007 , A61Q5/12 , Y10S514/844 , Y10S514/845 , Y10S514/846 , Y10S514/847 , Y10S514/937 , Y10S514/944
摘要： The invention relates to the use of aminoalcohol derivatives containing a urea functional group corresponding to the following formula: ##STR1## in which: R.sub.1 represents a linear or branched, saturated or unsaturated alkyl radical having from 8 to 22 carbon atoms;R.sub.2 represents a hydrogen atom or a linear or branched, saturated alkyl radical having from 1 to 6 carbon atoms;R.sub.3 represents a linear or branched, monohydroxylated or polyhydroxylated, saturated alkyl group having from 1 to 10 carbon atoms, in and for the preparation of cosmetic or dermatological compositions. These compounds are used in particular as moisturizing agents in care products for the skin or as conditioning agents in hair products.

8. 发明授权

US5972313A Active/stable artificial tanning compositions comprising DHA derivatives 失效
标题翻译：包含DHA衍生物的活性/稳定的人造鞣制组合物
公开(公告)号：US5972313A
公开(公告)日：1999-10-26
申请号：US819084
申请日：1997-03-18
申请人： Remy Tuloup , Christian Blaise , Michel Philippe , Daniel Sera , Armelle De Salvert
发明人： Remy Tuloup , Christian Blaise , Michel Philippe , Daniel Sera , Armelle De Salvert
IPC分类号： A61K8/35 , A61K8/37 , A61Q19/04 , C07C69/96 , C07D317/36 , C07D319/06 , A61K7/42
CPC分类号： C07D317/36 , A61K8/35 , A61K8/375 , A61Q19/04 , C07C69/96 , Y10S514/844 , Y10S514/846 , Y10S514/937 , Y10S514/938 , Y10S514/944
摘要： Stable, topically applicable cosmetic/dermatological compositions well suited for artificially tanning or browning human skin and appropriately packaged, comprise at least one dihydroxyacetone (DHA) derivative convertible into DHA and, advantageously, at least one active species for effecting such conversion.
摘要翻译：包含至少一种可转化成DHA的二羟基丙酮（DHA）衍生物和有利地至少一种用于实现这种转化的活性物质的适合于人造鞣制或褐变人皮肤并适当包装的化妆品/皮肤病学组合物。

9. 发明授权

US08771376B2 Composition comprising at least one 2-pyrrolidone functionalized with an ester or amide radical, and at least one pigment or direct dye, for dyeing keratin materials 有权
标题翻译：包含至少一种用酯或酰胺基团官能化的2-吡咯烷酮的组合物和至少一种用于染色角蛋白材料的颜料或直接染料
公开(公告)号：US08771376B2
公开(公告)日：2014-07-08
申请号：US13703040
申请日：2011-06-08
申请人： Stéphane Sabelle , Madeleine Leduc , Christian Blaise
发明人： Stéphane Sabelle , Madeleine Leduc , Christian Blaise
IPC分类号： A61Q5/10 , C07D207/00
CPC分类号： A61K8/4913 , A61K8/4946 , A61K8/4993 , A61K8/55 , A61Q5/065 , C07D207/277
摘要： The invention relates to a composition for dyeing keratin materials, and in particular human keratin fibres such as the hair, comprising at least one 2-pyrrolidone functionalized in the 4 position with an ester or amide radical, and at least one hydrophobic direct dye or a pigment; a dyeing process using this composition. Similarly, the invention relates to the use of the said pyrrolidone combined with a direct dye or a pigment for dyeing keratin materials, and especially to the use of the said pyrrolidone for improving the colour uptake onto the fibres of direct dyes that are sparingly soluble or insoluble in aqueous-alcoholic supports. The invention also relates to novel pyrrolidone derivatives. The present invention makes it possible in particular to obtain direct dyeing on keratin materials that is fast, resistant to washing, chromatic and powerful.
摘要翻译：本发明涉及一种用于染色角蛋白材料，特别是人角蛋白纤维如头发的组合物，其包含至少一种在4位上被酯或酰胺基官能化的2-吡咯烷酮和至少一种疏水直接染料或颜料; 使用该组合物的染色方法。类似地，本发明涉及所述吡咯烷酮与直接染料或颜料组合用于染色角蛋白材料的用途，特别涉及使用所述吡咯烷酮改善对微溶于直接染料的纤维上的颜色吸收，不溶于含水醇载体。本发明还涉及新的吡咯烷酮衍生物。本发明特别可以在快速，耐洗涤，有色和强力的角蛋白材料上获得直接染色。

10. 发明申请

US20140155352A1 COSMETIC TREATMENT PROCESSES AND KIT 有权
标题翻译：化妆品处理工艺和包装
公开(公告)号：US20140155352A1
公开(公告)日：2014-06-05
申请号：US14130597
申请日：2012-07-09
申请人： Anne-Claude Dublanchet , Christian Blaise
发明人： Anne-Claude Dublanchet , Christian Blaise
IPC分类号： A61K8/58 , A61Q3/00 , A61Q19/00 , A61K8/49 , A61Q5/00
CPC分类号： A61K8/4953 , A61K8/4926 , A61K8/4966 , A61K8/585 , A61K2800/43 , A61K2800/884 , A61Q3/00 , A61Q5/00 , A61Q5/10 , A61Q5/12 , A61Q17/04 , A61Q19/00
摘要： The present invention relates to a cosmetic process for treating keratin materials, which can give them, especially in a long-lasting and reversible manner, interesting cosmetic properties; this process comprising the application to said materials: in a first stage, of a cosmetic composition comprising at least one graftable species, comprising at least one unit of formula (Ia): and in a second stage, of a cosmetic composition comprising at least one cosmetic active agent bearing at least one unit of formula (Ia): The invention also relates to a kit comprising said compositions.
摘要翻译：本发明涉及一种用于治疗角蛋白材料的美容方法，其特别是以持久和可逆的方式给予它们有趣的化妆品性质; 该方法包括在第一阶段中应用包含至少一种可接枝物质的化妆品组合物的化妆品组合物，其包含至少一种式（Ia）单元：和在第二阶段中的包含至少一种含有至少一种式（Ia）单元的化妆品活性剂：本发明还涉及包含所述组合物的试剂盒。

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