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1. 发明授权

US07041210B2 Method of filling an amperometric cell 失效
公开(公告)号：US07041210B2
公开(公告)日：2006-05-09
申请号：US10387212
申请日：2003-03-10
申请人： Alastair M. Hodges , Thomas W. Beck , Ian A. Maxwell
发明人： Alastair M. Hodges , Thomas W. Beck , Ian A. Maxwell
IPC分类号： G01N27/327
CPC分类号： G01N27/3272
摘要： The invention relates to an amperometric electrochemical cell having a first insulating substrate carrying a first electrode, a second insulting substrate carrying a second electrode, said electrodes being disposed to face each other and spaced apart by less than 500 μm, and defining a sample reservoir therebetween, and wherein at least one, and preferably both, insulating substrates and the electrode carried thereon include an electromagnetic radiation transmissive portion in registration with said reservoir. The walls of the electrochemical cell may be formed from a thin metallic portion on a transparent substrate. Such cells are useful in providing visual confirmation of the validity of the electrochemical measurement.

2. 发明授权

US06592744B1 Method of filling an amperometric cell 失效
标题翻译：填充电流分析单元的方法
公开(公告)号：US06592744B1
公开(公告)日：2003-07-15
申请号：US09568076
申请日：2000-05-10
申请人： Alastair M Hodges , Thomas W. Beck , Ian A. Maxwell
发明人： Alastair M Hodges , Thomas W. Beck , Ian A. Maxwell
IPC分类号： G01N2726
CPC分类号： G01N27/3272
摘要： The invention relates to an amperometric electrochemical cell having a first insulating substrate carrying a first electrode, a second insulting substrate carrying a second electrode, said electrodes being disposed to face each other and spaced apart by less than 500 &mgr;m, and defining a sample reservoir therebetween, and wherein at least one, and preferably both, insulating substrates and the electrode carried thereon include an electromagnetic radiation transmissive portion in registration with said reservoir. The walls of the electrochemical cell may be formed from a thin metallic portion on a transparent substrate. Such cells are useful in providing visual confirmation of the validity of the electrochemical measurement.
摘要翻译：本发明涉及具有承载第一电极的第一绝缘衬底和承载第二电极的第二绝缘衬底的电流分析电化学电池，所述电极被设置为彼此面对并间隔小于500μm，并在其间限定一个样品容器并且其中至少一个绝缘基板和优选两个绝缘基板和其上承载的电极包括与所述储存器对准的电磁辐射透射部分。电化学电池的壁可以由透明基底上的薄金属部分形成。这样的细胞可用于提供电化学测量的有效性的视觉确认。

3. 发明授权

US06454921B1 Electrochemical cell 失效
标题翻译：电化学电池
公开(公告)号：US06454921B1
公开(公告)日：2002-09-24
申请号：US09404119
申请日：1999-09-23
申请人： Alastair M. Hodges , Thomas W. Beck , Ian A. Maxwell
发明人： Alastair M. Hodges , Thomas W. Beck , Ian A. Maxwell
IPC分类号： G01N2726
CPC分类号： G01N27/3272
摘要： The invention relates to an amperometric electrochemical cell having a first insulating substrate carrying a first electrode, a second insulting substrate carrying a second electrode, said electrodes being disposed to face each other and spaced apart by less than 500 &mgr;m, and defining a sample reservoir therebetween, and wherein at least one, and preferably both, insulating substrates and the electrode carried thereon include an electromagnetic radiation transmissive portion in registration with said reservoir. The walls of the electrochemical cell may be formed from a thin metallic portion on a transparent substrate. Such cells are useful in providing visual confirmation of the validity of the electrochemical measurement.
摘要翻译：本发明涉及具有承载第一电极的第一绝缘衬底和承载第二电极的第二绝缘衬底的电流分析电化学电池，所述电极被设置为彼此面对并间隔小于500μm，并在其间限定一个样品容器并且其中至少一个绝缘基板和优选两个绝缘基板和其上承载的电极包括与所述储存器对准的电磁辐射透射部分。电化学电池的壁可以由透明基底上的薄金属部分形成。这样的细胞可用于提供电化学测量的有效性的视觉确认。

4. 再颁专利

USRE44330E1 Electrochemical cell 有权
公开(公告)号：USRE44330E1
公开(公告)日：2013-07-02
申请号：US13100999
申请日：2011-05-04
申请人： Alastair M. Hodges , Thomas W. Beck , Oddvar Johansen
发明人： Alastair M. Hodges , Thomas W. Beck , Oddvar Johansen
IPC分类号： G01N27/327
CPC分类号： G01N27/403 , C12Q1/004 , G01N27/3272 , G01N27/3273 , Y10T29/49117
摘要： This invention relates to a biosensor and more particularly to an electrochemical biosensor for determining the concentration of an analyte in a carrier. The invention is particularly useful for determining the concentration of glucose in blood and is described herein with reference to that use but it should be understood that the invention is applicable to other analytic determinations.

5. 再颁专利

USRE42567E1 Electrochemical cell 有权
标题翻译：电化学电池
公开(公告)号：USRE42567E1
公开(公告)日：2011-07-26
申请号：US12899342
申请日：2010-10-06
申请人： Alastair M. Hodges , Thomas W. Beck , Oddvar Johansen , Ian Andrew Maxwell
发明人： Alastair M. Hodges , Thomas W. Beck , Oddvar Johansen , Ian Andrew Maxwell
IPC分类号： G01N27/327
CPC分类号： C12Q1/006 , C12Q1/004 , G01N27/3272
摘要： A biosensor for use in determining a concentration of a component in an aqueous liquid sample is provided including: an electrochemical cell having a first electrically resistive substrate having a thin layer of electrically conductive material, a second electrically resistive substrate having a thin layer of electrically conductive material, the substrates being disposed with the electrically conductive materials facing each other and being separated by a sheet including an aperture, the wall of which aperture defines a cell wall and a sample introduction aperture whereby the aqueous liquid sample may be introduced into the cell; and a measuring circuit.
摘要翻译：提供了一种用于确定含水液体样品中组分浓度的生物传感器，包括：电化学电池，具有具有导电材料薄层的第一电阻衬底，具有导电薄层的第二电阻衬底材料，所述基板被布置成导电材料相互面对并由包括孔的片分隔开，所述片的壁的孔限定细胞壁和样品引入孔，由此可将水性液体样品引入细胞中; 和测量电路。

6. 发明授权

US06555005B1 Scouring method 有权
公开(公告)号：US06555005B1
公开(公告)日：2003-04-29
申请号：US09336059
申请日：1999-06-18
申请人： Fufang Zha , Clinton V. Kopp , Robert J. McMahon , Warren T. Johnson , Thomas W. Beck
发明人： Fufang Zha , Clinton V. Kopp , Robert J. McMahon , Warren T. Johnson , Thomas W. Beck
IPC分类号： B01F6100
CPC分类号： B01D65/08 , B01D61/18 , B01D63/022 , B01D63/024 , B01D63/16 , B01D65/02 , B01D2315/06 , B01D2321/04 , B01D2321/16 , B01D2321/168 , B01D2321/185 , B01D2321/2058
摘要： A method and apparatus for removing fouling materials from the surface of a plurality of porous membranes (9) arranged in a membrane module (4) by providing, from within the module, by means (10) other than gas passing through the pores of said membranes, gas bubbles in a uniform distribution relative to the porous membrane array such that the bubbles move past the surfaces of the membranes (9) to dislodge fouling materials therefrom. The membranes (9) are arranged in close proximity to one another and mounted to prevent excessive movement therebetween. The bubbles also produce vibration and rubbing together of the membranes to further assist removal of fouling materials.

7. 发明授权

US6156200A Gas-scrubbed hollow fiber membrane module 有权
标题翻译：气体洗涤中空纤维膜组件
公开(公告)号：US6156200A
公开(公告)日：2000-12-05
申请号：US208294
申请日：1998-12-08
申请人： Fufang Zha , Clinton V. Kopp , Robert J. McMahon , Warren T. Johnson , Thomas W. Beck
发明人： Fufang Zha , Clinton V. Kopp , Robert J. McMahon , Warren T. Johnson , Thomas W. Beck
IPC分类号： B01D61/18 , B01D63/02 , B01D63/16 , B01D65/02 , B01D65/08 , B01D63/04
CPC分类号： B01D65/08 , B01D61/18 , B01D63/022 , B01D63/024 , B01D63/16 , B01D65/02 , B01D2321/12 , B01D2321/185 , B01D2321/2058
摘要： A method and apparatus for removing fouling materials from the surface of a plurality of porous membranes (9) arranged in a membrane module (4) by providing, from within the module, by means (10) other than gas passing through the pores of said membranes, gas bubbles in a uniform distribution relative to the porous membrane array such that the bubbles move past the surfaces of the membranes (9) to dislodge fouling materials therefrom. The membranes (9) are arranged in close proximity to one another and mounted to prevent excessive movement therebetween. The bubbles also produce vibration and rubbing together of the membranes to further assist removal of fouling materials.
摘要翻译：一种从多个多孔膜（9）的表面排出污垢材料的方法和装置，该多孔隔膜（9）通过从模块内部通过除气体之外的装置（10）提供布置在膜组件膜，相对于多孔膜阵列均匀分布的气泡，使得气泡通过膜（9）的表面移动以从其中去除污垢材料。膜（9）彼此靠近地布置并且被安装以防止它们之间的过度移动。气泡也会产生振动并将膜摩擦在一起，以进一步帮助去除污垢物质。

8. 发明授权

US07431814B2 Electrochemical cell 有权
标题翻译：电化学电池
公开(公告)号：US07431814B2
公开(公告)日：2008-10-07
申请号：US10843956
申请日：2004-05-12
申请人： Alastair Hodges , Thomas W. Beck , Oddvar Johansen , Ian Andrew Maxwell
发明人： Alastair Hodges , Thomas W. Beck , Oddvar Johansen , Ian Andrew Maxwell
IPC分类号： G01N27/427
CPC分类号： C12Q1/004 , C12Q1/006 , G01N27/3272
摘要： A biosensor for use in determining a concentration of a component in an aqueous liquid sample is provided including: an electrochemical cell having a first electrically resistive substrate having a thin layer of electrically conductive material, a second electrically resistive substrate having a thin layer of electrically conductive material, the substrates being disposed with the electrically conductive materials facing each other and being separated by a sheet including an aperture, the wall of which aperture defines a cell wall and a sample introduction aperture whereby the aqueous liquid sample may be introduced into the cell; and a measuring circuit.
摘要翻译：提供了一种用于确定含水液体样品中组分浓度的生物传感器，包括：电化学电池，具有具有导电材料薄层的第一电阻衬底，具有导电薄层的第二电阻衬底材料，所述基板被布置成导电材料相互面对并由包括孔的片分隔开，所述片的壁的孔限定细胞壁和样品引入孔，由此可将水性液体样品引入细胞中; 和测量电路。

9. 发明授权

US06475360B1 Heated electrochemical cell 失效
公开(公告)号：US06475360B1
公开(公告)日：2002-11-05
申请号：US09659470
申请日：2000-09-11
申请人： Alastair Hodges , Thomas W. Beck
发明人： Alastair Hodges , Thomas W. Beck
IPC分类号： G01N27327
CPC分类号： G01N27/3272
摘要： The invention provides a method for determining the concentration of an analyte in a sample comprising the steps of heating the sample and measuring the concentration of the analyte or the concentration of a species representative thereof in the sample at a predetermined point on a reaction profile by means that are substantially independent of temperature. Also provided is an electrochemical cell comprising a spacer pierced by an aperture which defines a cell wall, a first metal electrode on one side of the spacer extending over one side of the aperture, a second metal electrode on the other side of the spacer extending over the side of the aperture opposite the first electrode, means for admitting a sample to the cell volume defined between the electrodes and the cell wall, and means for heating a sample contained within the cell.

10. 发明授权

US06878251B2 Heated electrochemical cell 失效
标题翻译：加热电化学电池
公开(公告)号：US06878251B2
公开(公告)日：2005-04-12
申请号：US10079063
申请日：2002-02-19
申请人： Alastair Hodges , Thomas W. Beck
发明人： Alastair Hodges , Thomas W. Beck
IPC分类号： G01N27/403 , G01N33/487 , G01N27/327 , G01N27/333
CPC分类号： G01N27/3272
摘要： The invention provides a method for determining the concentration of an analyte in a sample comprising the steps of heating the sample and measuring the concentration of the analyte or the concentration of a species representative thereof in the sample at a predetermined point on a reaction profile by means that are substantially independent of temperature. Also provided is an electrochemical cell comprising a spacer pierced by an aperture which defines a cell wall, a first metal electrode on one side of the spacer extending over one side of the aperture, a second metal electrode on the other side of the spacer extending over the side of the aperture opposite the first electrode, means for admitting a sample to the cell volume defined between the electrodes and the cell wall, and means for heating a sample contained within the cell.
摘要翻译：本发明提供了一种用于确定样品中分析物浓度的方法，包括以下步骤：在反应曲线上的预定点处加热样品并测量分析物的浓度或样品中代表其的物质的浓度其基本上与温度无关。还提供了一种电化学电池，其包括由限定电池壁的孔刺穿的间隔件，在间隔物的一侧延伸的孔的一侧上的第一金属电极，在隔板的另一侧延伸的第二金属电极所述孔的与所述第一电极相对的一侧，用于将样品接纳到限定在所述电极和所述细胞壁之间的细胞体积的装置，以及用于加热所述细胞内包含的样品的装置。

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