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1. 发明授权

US07731681B2 Catheter positioning system 有权
标题翻译：导管定位系统
公开(公告)号：US07731681B2
公开(公告)日：2010-06-08
申请号：US10805738
申请日：2004-03-22
申请人： Alan K. Schaer , Michael D. Lesh
发明人： Alan K. Schaer , Michael D. Lesh
IPC分类号： A61M35/00
CPC分类号： A61M25/0668 , A61B17/22012 , A61B18/1492 , A61B2017/003 , A61B2017/00867 , A61B2017/22038 , A61B2018/00214 , A61B2018/00285 , A61B2018/00577 , A61B2018/00839 , A61M2210/125 , A61N7/02 , C08L2201/12
摘要： The present invention relates to a system adapted to position a medical device, such as an ablation catheter, at a location where a pulmonary vein extends from an atrium. The system optimally includes a deflectable catheter and a sheath. An ablation member is disclosed for use with the positioning system, wherein the deflectable catheter and the sheath cooperate so as to facilitate positioning of the ablation member at the location.
摘要翻译：本发明涉及一种适于将医疗装置（例如消融导管）定位在肺静脉从心房延伸的位置处的系统。该系统最佳地包括可偏转导管和护套。公开了一种与定位系统一起使用的消融构件，其中可偏转导管和护套配合，以便于消融构件在该位置的定位。

2. 发明授权

US06758830B1 Catheter positioning system 有权
标题翻译：导管定位系统
公开(公告)号：US06758830B1
公开(公告)日：2004-07-06
申请号：US09569734
申请日：2000-05-11
申请人： Alan K. Schaer , Michael D. Lesh
发明人： Alan K. Schaer , Michael D. Lesh
IPC分类号： A61M3500
CPC分类号： A61M25/0668 , A61B17/22012 , A61B18/1492 , A61B2017/003 , A61B2017/00867 , A61B2017/22038 , A61B2018/00214 , A61B2018/00285 , A61B2018/00577 , A61B2018/00839 , A61M2210/125 , A61N7/02 , C08L2201/12
摘要： The present invention relates to a system adapted to position an ablation catheter at a location where a pulmonary vein extends from an atrium. The system includes a deflection device and a sheath and optionally uses a guidewire. An ablation catheter is disclosed for use with the positioning system, wherein the deflection device and the sheath cooperate so as to facilitate positioning of the catheter at the location.
摘要翻译：本发明涉及一种适于将消融导管定位在肺静脉从心房延伸的位置处的系统。该系统包括偏转装置和护套，并且可选地使用导丝。公开了与定位系统一起使用的消融导管，其中偏转装置和护套配合以便于将导管定位在该位置。

3. 发明授权

US06547788B1 Medical device with sensor cooperating with expandable member 有权
标题翻译：带传感器的医疗设备与可扩展部件配合使用
公开(公告)号：US06547788B1
公开(公告)日：2003-04-15
申请号：US09517614
申请日：2000-03-02
申请人： Mark A. Maguire , Martin F. O'Sullivan , Edward L. Carcamo , Michael D. Lesh , Alan K. Schaer , Kevin J. Taylor , Guillermo P. Picazo
发明人： Mark A. Maguire , Martin F. O'Sullivan , Edward L. Carcamo , Michael D. Lesh , Alan K. Schaer , Kevin J. Taylor , Guillermo P. Picazo
IPC分类号： A61B1818
CPC分类号： A61B18/00 , A61B18/1492 , A61B2017/00243 , A61B2018/00083 , A61B2018/00148 , A61B2018/00214 , A61M25/1002 , A61M2210/125 , A61N7/02 , A61N7/022
摘要： A tissue ablation catheter for forming a lesion along a substantially circumferential region of tissue is described. The catheter includes one or more sensors for monitoring the temperature of the tissue being ablated. The temperature sensors are mounted on the interior or exterior of an expandable member that is affixed to a shaft of the catheter.
摘要翻译：描述了用于沿着组织的基本圆周区域形成病变的组织消融导管。该导管包括一个或多个传感器，用于监测被消融的组织的温度。温度传感器安装在固定到导管的轴上的可扩张构件的内部或外部。

4. 发明授权

US06869431B2 Medical device with sensor cooperating with expandable member 有权
标题翻译：带传感器的医疗设备与可扩展部件配合使用
公开(公告)号：US06869431B2
公开(公告)日：2005-03-22
申请号：US09949479
申请日：2001-09-07
申请人： Mark A. Maguire , Martin F. O'Sullivan , Edward L. Carcamo , Michael D. Lesh , Alan K. Schaer , Kevin J. Taylor , Guillermo P. Picazo
发明人： Mark A. Maguire , Martin F. O'Sullivan , Edward L. Carcamo , Michael D. Lesh , Alan K. Schaer , Kevin J. Taylor , Guillermo P. Picazo
IPC分类号： A61B17/00 , A61B17/22 , A61B18/00 , A61B18/14 , A61B19/00 , A61N7/02 , A61B18/18
CPC分类号： A61B18/00 , A61B18/1492 , A61B2017/00092 , A61B2017/00243 , A61B2017/00526 , A61B2017/22051 , A61B2017/22067 , A61B2018/00065 , A61B2018/00214 , A61B2018/0022 , A61B2018/00285 , A61B2018/00357 , A61B2018/00369 , A61B2018/00375 , A61B2018/00702 , A61B2018/00791 , A61B2018/1253 , A61B2090/3784 , A61N7/02
摘要： Disclosed is a method for attaching a sensor to an inflatable balloon. The method involves bonding the sensor to the balloon with an adhesive while the balloon is in an expanded state and then collapsing the balloon after the adhesive has at least partially cured. The method reduces the possibility of a failure of the bond between the sensor and the balloon. The method is particularly useful in the construction of a tissue ablation catheter for forming a lesion along a substantially circumferential region of tissue wherein a sensor is used for monitoring the temperature of the tissue being ablated.
摘要翻译：公开了一种将传感器附接到可充气球囊的方法。该方法包括使用粘合剂将传感器粘合到球囊上，同时气囊处于膨胀状态，然后在粘合剂具有至少部分固化之后使囊膨胀。该方法降低了传感器和气囊之间的接合故障的可能性。该方法特别可用于组织消融导管的构造，用于沿着组织的基本圆周区域形成病变，其中传感器用于监测被消融的组织的温度。

5. 发明授权

US06953460B2 Medical device with sensor cooperating with expandable member 有权
标题翻译：带传感器的医疗设备与可扩展部件配合使用
公开(公告)号：US06953460B2
公开(公告)日：2005-10-11
申请号：US10356418
申请日：2003-01-31
申请人： Mark A. Maguire , Martin F. O'Sullivan , Edward L. Carcamo , Michael D. Lesh , Alan K. Schaer , Kevin J. Taylor , Guillermo P. Picazo
发明人： Mark A. Maguire , Martin F. O'Sullivan , Edward L. Carcamo , Michael D. Lesh , Alan K. Schaer , Kevin J. Taylor , Guillermo P. Picazo
IPC分类号： A61B17/00 , A61B18/00 , A61B18/18 , A61N7/02 , A61B10/04
CPC分类号： A61B18/00 , A61B18/1492 , A61B2017/00243 , A61B2018/00083 , A61B2018/00148 , A61B2018/00214 , A61M25/1002 , A61M2210/125 , A61N7/02 , A61N7/022
摘要： A tissue ablation catheter for forming a lesion along a substantially circumferential region of tissue is described. The catheter includes one or more sensors for monitoring the temperature of the tissue being ablated. The temperature sensors are mounted on the interior or exterior of an expandable member that is affixed to a shaft of the catheter.
摘要翻译：描述了用于沿着组织的基本圆周区域形成病变的组织消融导管。该导管包括一个或多个传感器，用于监测被消融的组织的温度。温度传感器安装在固定到导管的轴上的可扩张构件的内部或外部。

6. 发明授权

US06514249B1 Positioning system and method for orienting an ablation element within a pulmonary vein ostium 有权
标题翻译：用于定向消融元件在肺静脉口内的定位系统和方法
公开(公告)号：US06514249B1
公开(公告)日：2003-02-04
申请号：US09517472
申请日：2000-03-02
申请人： Mark A. Maguire , Martin F. O'Sullivan , Edward L. Carcamo , Michael D. Lesh , Alan K. Schaer , Kevin J. Taylor , Guillermo P. Picazo
发明人： Mark A. Maguire , Martin F. O'Sullivan , Edward L. Carcamo , Michael D. Lesh , Alan K. Schaer , Kevin J. Taylor , Guillermo P. Picazo
IPC分类号： A61B1818
CPC分类号： A61N7/02 , A61B18/00 , A61B18/1492 , A61B2017/00106 , A61B2017/00243 , A61B2018/00214 , A61B2018/00261
摘要： This invention relates to a surgical device and method. More particularly, it relates to a tissue ablation device assembly and method using a circumferential ablation member in combination with a position monitoring assembly in order to position the circumferential ablation member along a circumferential region of tissue at a location where a pulmonary vein extends from a left atrium.
摘要翻译：本发明涉及一种手术装置和方法。更具体地，本发明涉及一种组织消融装置组件和使用周边消融部件与位置监测组件组合的方法，以便沿着肺静脉从左侧延伸的位置沿着组织的周边区域定位周边消融部件心房

7. 发明申请

US20130035628A1 METHODS AND SYSTEMS FOR TREATMENT OF ACUTE ISCHEMIC STROKE 审中-公开
标题翻译：治疗急性脑缺血发作的方法和系统
公开(公告)号：US20130035628A1
公开(公告)日：2013-02-07
申请号：US13566451
申请日：2012-08-03
申请人： Michi E. Garrison , Tony M. Chou , Gregory M. Hyde , Alan K. Schaer
发明人： Michi E. Garrison , Tony M. Chou , Gregory M. Hyde , Alan K. Schaer
IPC分类号： A61B17/22 , A61M25/14 , A61M25/10 , A61M1/00
CPC分类号： A61B17/22 , A61B17/221 , A61B17/32037 , A61B2017/22034 , A61B2017/22038 , A61B2017/22039 , A61B2017/22044 , A61B2017/22054 , A61B2017/22084 , A61B2017/22094 , A61B2017/2212 , A61B2017/2217 , A61F2/013 , A61M1/0072 , A61M1/1037 , A61M1/1062 , A61M1/3621 , A61M25/0068 , A61M25/0169 , A61M25/0662 , A61M2025/0681
摘要： Described are methods and systems for transcervical access of the cerebral arterial vasculature and treatment of cerebral occlusions, including ischemic stroke. The methods and devices may include methods and devices which may provide aspiration and passive flow reversal, those which protect the cerebral penumbra during the procedure to minimize injury to brain, as well as distal catheters and devices to remove an occlusion. The methods and devices that provide passive flow reversal may also offer to the user a degree of flow control. Devices and methods which provide a way to securely close the access site in the carotid artery to avoid the potentially devastating consequences of a transcervical hematoma are also described.
摘要翻译：描述了脑动脉脉管系统的子宫颈进入和脑阻塞治疗（包括缺血性卒中）的方法和系统。方法和装置可以包括可以提供抽吸和被动流逆转的方法和装置，那些在手术期间保护脑半暗带以最小化对脑的损伤，以及用于去除闭塞的远端导管和装置的方法和装置。提供被动流逆转的方法和装置也可以向用户提供一定程度的流量控制。还描述了提供一种方法来安全地关闭颈动脉中的进入部位以避免子宫颈血肿的潜在破坏性后果的装置和方法。

8. 发明授权

US06251107B1 Ep catheter 失效
标题翻译： Ep导管
公开(公告)号：US06251107B1
公开(公告)日：2001-06-26
申请号：US09104752
申请日：1998-06-25
申请人： Alan K. Schaer
发明人： Alan K. Schaer
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2018/1437
摘要： A low profile intravascular electrophysiology (EP) device for the formation of linear lesions which has particular utility in the treatment of atrial fibrillation and flutter. The EP device of the invention has an elongated shaft with a proximal section, a distal section, and a plurality of at least partially exposed electrodes disposed on an outer surface of the distal section. The electrodes are spaced along a length of the distal section with at least one temperature sensor located between adjacent electrodes. High frequency, e.g. RF, electrical energy delivered to the electrodes on the distal shaft section of the EP device will form a linear lesion which terminates the fibrillation or flutter.
摘要翻译：用于形成线性病变的低调血管内电生理学（EP）装置，其在治疗心房颤动和颤动中具有特别的用途。本发明的EP装置具有细长轴，其具有近端部分，远侧部分和设置在远侧部分的外表面上的多个至少部分暴露的电极。电极沿着远端部分的长度间隔开，并具有位于相邻电极之间的至少一个温度传感器。高频率，例如 RF，传送到EP装置的远侧轴部分上的电极的电能将形成线性损伤，其终止原纤维或扑动。

9. 发明授权

US07276061B2 Irrigated ablation device assembly 有权
标题翻译：灌肠消融装置组装
公开(公告)号：US07276061B2
公开(公告)日：2007-10-02
申请号：US10288739
申请日：2002-11-06
申请人： Alan K. Schaer , Aurelio Valencia
发明人： Alan K. Schaer , Aurelio Valencia
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2017/22038 , A61B2018/00011 , A61B2018/00029 , A61B2018/00065 , A61B2018/0016 , A61B2018/00214 , A61B2018/00797 , A61B2018/00821 , A61B2018/1437 , A61B2218/002
摘要： A tissue ablation device assembly ablates a region of tissue in a body of a patient. The tissue ablation device assembly comprises an elongated body having a proximal end portion and a distal end portion. A tubular porous membrane having a porous wall with an inner surface that defines an inner space is located along the distal end portion of the elongated body. An ablation element is disposed over the porous membrane, with the ablation element having a fixed position with respect to the porous membrane. A fluid passageway extending through the elongated body and communicates with the inner space. The fluid passageway is adapted to be fluidly coupled to a pressurizeable fluid source for delivering a volume of pressurized fluid from the fluid source to the inner space. The porous membrane allows at least a substantial portion of the volume of pressurized fluid to pass through the porous wall for enhancing ablative coupling between the electrode and the region of tissue.
摘要翻译：组织消融装置组件消融患者体内的组织区域。组织消融装置组件包括具有近端部分和远端部分的细长主体。具有限定内部空间的具有内表面的多孔壁的管状多孔膜沿着细长体的远端部分定位。消融元件设置在多孔膜上，消融元件相对于多孔膜具有固定位置。流体通道延伸穿过细长主体并与内部空间连通。流体通道适于流体地联接到可加压流体源，用于将一定体积的加压流体从流体源输送到内部空间。多孔膜允许加压流体体积的至少大部分通过多孔壁以增强电极和组织区域之间的消融耦合。

10. 发明授权

US06599288B2 Apparatus and method incorporating an ultrasound transducer onto a delivery member 有权
公开(公告)号：US06599288B2
公开(公告)日：2003-07-29
申请号：US09859083
申请日：2001-05-16
申请人： Mark A. Maguire , James C. Peacock, III , Alan K. Schaer , Veijo Suorsa
发明人： Mark A. Maguire , James C. Peacock, III , Alan K. Schaer , Veijo Suorsa
IPC分类号： A61B1818
CPC分类号： A61B17/2202 , A61B8/4245 , A61B18/1492 , A61B2017/00243 , A61B2017/00477 , A61B2017/22027 , A61B2017/22051 , A61B2017/320088 , A61B2018/00023 , A61B2018/00214 , A61B2018/0022 , A61B2018/00898
摘要： A medical device assembly and method provides an ultrasound transducer mounted onto a catheter shaft. The ultrasound transducer is mounted such that there is a radial separation between the transducer and the underlying catheter shaft. The transducer is mounted on support structures which do not bridge the gap between the transducer and delivery member. The location of the support structures provides for an “airbacked” transducer that is very efficient and prevents heat build-up in the materials in contact therewith.

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