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1. 发明授权

US08788066B2 Implant tool and improved electrode design for minimally invasive procedure 有权
标题翻译：植入物工具和改进的电极设计用于微创手术
公开(公告)号：US08788066B2
公开(公告)日：2014-07-22
申请号：US13540218
申请日：2012-07-02
申请人： Adam Cates , Eric Lovett , Loren Murney , Kip Ludwig , Paul Pignato , Brian Soltis
发明人： Adam Cates , Eric Lovett , Loren Murney , Kip Ludwig , Paul Pignato , Brian Soltis
IPC分类号： A61N1/18 , A61N1/05 , A61N1/36
CPC分类号： A61N1/05 , A61N1/0558 , A61N1/36117 , A61N1/36139 , A61N1/36157 , A61N1/36171 , A61N1/36175 , A61N1/36182
摘要： Devices and methods of use for introduction and implantation of an electrode as part of a minimally invasive technique. An implantable baroreflex activation system includes a control system having an implantable housing, an electrical lead, attachable to the control system, and an electrode structure. The electrode structure is near one end of the electrical lead, and includes a monopolar electrode, a backing material having an effective surface area larger than the electrode, and a releasable pivotable interface to mate with an implant tool. The electrode is configured for implantation on an outer surface of a blood vessel and the control system is programmed to deliver a baroreflex therapy via the monopolar electrode to a baroreceptor within a wall of the blood vessel.
摘要翻译：用于引入和植入电极作为微创技术的一部分的装置和方法。可植入压力反射激活系统包括具有可植入壳体，可引导到控制系统的电引线和电极结构的控制系统。电极结构靠近电引线的一端，并且包括单极电极，具有大于电极的有效表面积的背衬材料以及与植入工具配合的可释放的可枢转接口。电极被配置为植入在血管的外表面上，并且控制系统被编程为通过单极电极将压力反射治疗递送到血管壁内的压力感受器。

2. 发明申请

US20120271389A1 IMPLANT TOOL AND IMPROVED ELECTRODE DESIGN FOR MINIMALLY INVASIVE PROCEDURE 有权
标题翻译：嵌入式工具和改进的电极设计，用于最小的入侵程序
公开(公告)号：US20120271389A1
公开(公告)日：2012-10-25
申请号：US13540218
申请日：2012-07-02
申请人： Adam Cates , Eric Lovett , Loren Murney , Kip Ludwig , Paul Pignato , Brian Soltis
发明人： Adam Cates , Eric Lovett , Loren Murney , Kip Ludwig , Paul Pignato , Brian Soltis
IPC分类号： A61N1/375
CPC分类号： A61N1/05 , A61N1/0558 , A61N1/36117 , A61N1/36139 , A61N1/36157 , A61N1/36171 , A61N1/36175 , A61N1/36182
摘要： Devices and methods of use for introduction and implantation of an electrode as part of a minimally invasive technique. An implantable baroreflex activation system includes a control system having an implantable housing, an electrical lead, attachable to the control system, and an electrode structure. The electrode structure is near one end of the electrical lead, and includes a monopolar electrode, a backing material having an effective surface area larger than the electrode, and a releasable pivotable interface to mate with an implant tool. The electrode is configured for implantation on an outer surface of a blood vessel and the control system is programmed to deliver a baroreflex therapy via the monopolar electrode to a baroreceptor within a wall of the blood vessel.
摘要翻译：用于引入和植入电极作为微创技术的一部分的装置和方法。可植入压力反射激活系统包括具有可植入壳体，可引导到控制系统的电引线和电极结构的控制系统。电极结构靠近电引线的一端，并且包括单极电极，具有大于电极的有效表面积的背衬材料以及与植入工具配合的可释放的可枢转接口。电极被配置为植入在血管的外表面上，并且控制系统被编程为通过单极电极将压力反射治疗递送到血管壁内的压力感受器。

3. 发明申请

US20120109250A1 IMPLANT TOOL AND IMPROVED ELECTRODE DESIGN FOR MINIMALLY INVASIVE PROCEDURE 有权
公开(公告)号：US20120109250A1
公开(公告)日：2012-05-03
申请号：US13286169
申请日：2011-10-31
申请人： Adam Cates , Eric Lovett , Loren Murney , Kip Ludwig , Paul Pignato , Brian Soltis
发明人： Adam Cates , Eric Lovett , Loren Murney , Kip Ludwig , Paul Pignato , Brian Soltis
IPC分类号： A61N1/372
CPC分类号： A61N1/05 , A61N1/0558 , A61N1/36117 , A61N1/36139 , A61N1/36157 , A61N1/36171 , A61N1/36175 , A61N1/36182
摘要： Devices and methods of use for introduction and implantation of an electrode as part of a minimally invasive technique. An implantable baroreflex activation system includes a control system having an implantable housing, an electrical lead, attachable to the control system, and an electrode structure. The electrode structure is near one end of the electrical lead, and includes a monopolar electrode, a backing material having an effective surface area larger than the electrode, and a releasable pivotable interface to mate with an implant tool. The electrode is configured for implantation on an outer surface of a blood vessel and the control system is programmed to deliver a baroreflex therapy via the monopolar electrode to a baroreceptor within a wall of the blood vessel.

4. 发明授权

US08715327B1 Baroreflex modulation using light-based stimulation 有权
标题翻译：使用基于光的刺激进行Baroreflex调制
公开(公告)号：US08715327B1
公开(公告)日：2014-05-06
申请号：US12798966
申请日：2010-04-13
申请人： Eric G. Lovett , Kip Ludwig
发明人： Eric G. Lovett , Kip Ludwig
IPC分类号： A61N5/06
CPC分类号： A61N5/0622 , A61N2005/0602 , A61N2005/0643 , A61N2005/0659 , A61N2005/0661 , A61N2005/0662
摘要： A system for stimulating a baroreflex of a patient that includes a first light source with a first emitter for emitting a first light, the first emitter at a first location proximate a target tissue having baroreceptor cells, and a second light source including a second emitter and for emitting a second light, the second emitter at a second location proximate the target tissue. The system also includes a control circuit coupled to the first and the second light sources, the control circuit configured to activate the first and the second light sources such that the first light traverses a first pathway to arrive at and penetrate the first portion of the target tissue and the second light-like traverses a second pathway to arrive at and penetrate the second portion of the target tissue, thereby stimulating the baroreceptor cells and activating a baroreflex of the patient.
摘要翻译：一种用于刺激患者的压力反射的系统，其包括具有用于发射第一光的第一发射器的第一光源，在靠近具有压力感受器单元的靶组织的第一位置处的第一发射器和包括第二发射器的第二光源用于在靠近目标组织的第二位置处发射第二个光，第二个发射器。该系统还包括耦合到第一和第二光源的控制电路，该控制电路被配置为激活第一和第二光源，使得第一光穿过第一路径到达并穿透目标的第一部分组织并且第二光线穿过第二通道以到达并穿透靶组织的第二部分，从而刺激压力感受器细胞并激活患者的压力反射。

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