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1. 发明申请

US20140309683A1 Miniature Device Platform for Navigation on Moving Organs 审中-公开
标题翻译：移动机关导航微型设备平台
公开(公告)号：US20140309683A1
公开(公告)日：2014-10-16
申请号：US14251615
申请日：2014-04-13
申请人： Actuated Medical, Inc.
发明人： Roger B Bagwell , Brian Matthew Park , Casey A. Scruggs , Kevin A. Snook
IPC分类号： A61B17/29
CPC分类号： A61B17/29 , A61B1/00087 , A61B1/0014 , A61B17/22031 , A61B18/1492 , A61B2017/2943 , A61B2017/2947 , A61B2018/00208 , A61B2018/00291 , A61B2018/1405 , A61B2218/002 , A61B2218/007
摘要： A device for gripping tissue that is inside of a patient for use in delivering therapy is provided. The device may include a first gear that rotates and that engages the tissue. A second gear that also rotates may be included and may likewise engage the tissue. A spacing mechanism may be included in the device that adjusts the spacing between the first and second gears such that the first and second gears are moved closer to one another and moved farther from one another.
摘要翻译：提供了一种用于夹持用于输送治疗的患者体内的组织的装置。该装置可以包括旋转并接合组织的第一齿轮。也可以包括旋转的第二齿轮并且可以同样地接合组织。调节第一和第二齿轮之间的间距的装置中可以包括间隔机构，使得第一和第二齿轮彼此靠近并且彼此移动得更远。

2. 发明公开

US20240366966A1 DEVICE AND METHOD FOR REDUCING INJURY RESPONSE IN INJURED TISSUE 审中-公开
公开(公告)号：US20240366966A1
公开(公告)日：2024-11-07
申请号：US18743214
申请日：2024-06-14
申请人： Actuated Medical, Inc.
发明人： Roger B. Bagwell , Maureen L. Mulvihill , Kyle W. Gheres , Jenna K. Greaser , Kevin A. Snook
IPC分类号： A61N7/00
CPC分类号： A61N7/00
摘要： An assembly for reducing foreign body response in a subject caused by an invasive or non-invasive tissue injury at a target site. A base with aperture is secured to the subject in proximity to the target site with an implant extending therethrough. The base includes a sloped channel that receives an alignment tab of a housing, permitting vertical adjustment of the housing relative to the base along a continuum by rotation of the housing. The housing contains a transducer generating vibrations when activated, an acoustic horn in contact with the transducer transmitting the vibrations through the base aperture to the subject tissue at the target site, and a compressible polymer surrounding a portion of the horn at the terminal end of the housing that conforms to the subject's interface and transmits vibrations to the target site for reducing foreign body response or microgliosis in the subject.

3. 发明申请

US20220322916A1 Device for Aiding in the Positioning and Anchoring of an Endoscope During Gastrointestinal Procedures 有权
公开(公告)号：US20220322916A1
公开(公告)日：2022-10-13
申请号：US17839989
申请日：2022-06-14
申请人： Actuated Medical, Inc.
发明人： Roger B. Bagwell , Eric J. Hopkins , Casey A. Scruggs , Kevin A. Snook
IPC分类号： A61B1/00 , A61B17/29
摘要： A medical instrument having integrated arms extending from a proximal end to a distal end, and a handpiece with actuators to control movement of the arms. The instrument includes an insertion tube having arm channel(s) for receiving an arm therethrough. Each arm includes an engagement member at the distal end of resilient material with a natural non-linear configuration when deployed but deforming when retracted into the arm channel when retracted. Arm channels may be located at different radial distances from one another in the insertion tube so the engagement members may be at radial angles relative to one another when deployed. Arms and engagement members are movable between at least a first position and second position relative to one another by rotation and/or translational motion of the corresponding actuator, to contact tissue or deflect a tool extended through the working channel of the endoscope.

4. 发明申请

US20190015125A1 Device for Aiding in the Positioning and Anchoring of an Endoscope During Gastrointestinal Procedures 审中-公开
公开(公告)号：US20190015125A1
公开(公告)日：2019-01-17
申请号：US16034965
申请日：2018-07-13
申请人： Actuated Medical, Inc.
发明人： Roger B. Bagwell , Timothy J. Higgins , Eric J. Hopkins , Casey A. Scruggs , Kevin A. Snook
IPC分类号： A61B17/29
摘要： A device for engaging tissue includes a body disposable around the distal end of a medical instrument, such as an endoscope, and a handpiece. The body includes a primary channel for receiving the medical instrument and at least one arm channel for receiving an arm therethrough. At least one arm extends through the arm channel of the body and proximally to the handpiece. The arm includes an engagement member distally of the body, and may further include a bend between the body and engagement member. The engagement member is movable between a first position not contacting tissue and a second position contacting tissue. With multiple engagement members, the engagement members are farther apart from one another in the first position and closer together in the second position. Movement of the engagement members is controlled by selective and independent movement of the corresponding arms by rotational and/or translational motion.

5. 发明申请

US20200261113A1 Device and Method for Automated Insertion of Penetrating Member 审中-公开
公开(公告)号：US20200261113A1
公开(公告)日：2020-08-20
申请号：US16837675
申请日：2020-04-01
申请人： Actuated Medical, Inc. , Ex Machina Medical LLC
发明人： Roger B. Bagwell , Ryan S. Clement , Maureen L. Mulvihill , Casey A. Scruggs , Kevin A. Snook , William E. Cohn , James Patrick Herlihy , Kenneth Wayne Rennicks
IPC分类号： A61B17/34
摘要： An automatic insertion device and method of using the same is provided. A vibrator and an extender are connected to a penetrating member and are both in electrical communication with a controller. A detector identifies a subcutaneous target for insertion and the insertion angle, distance and trajectory for the penetrating member are calculated. The vibrator provides vibrations to the penetrating member and the extender advances the penetrating member for insertion. The vibrator and extender are in electrical communication with one another during the insertion process and adjustments to the insertion speed are made based on feedback of vibrational load encountered by the vibrator during insertion, and adjustments to the vibrations are made based on feedback of insertion load encountered by the extender during insertion. Iterative samples are taken to constantly adjust the operation of one motor based on the operations and feedback from the other motor.

6. 发明申请

US20160346519A1 Reduced Force Device for Intravascular Access and Guidewire Placement 有权
标题翻译：用于血管内通路和导丝放置的减压装置
公开(公告)号：US20160346519A1
公开(公告)日：2016-12-01
申请号：US15205357
申请日：2016-07-08
申请人： Actuated Medical, Inc.
发明人： Roger B. Bagwell , Ryan S. Clement , Maureen L. Mulvihill , Casey A. Scruggs , Kevin A. Snook
IPC分类号： A61M25/09 , A61B5/15 , A61B10/02 , A61M25/06 , A61B17/34
CPC分类号： A61M25/09041 , A61B5/15003 , A61B5/150137 , A61B5/150389 , A61B10/0233 , A61B10/025 , A61B17/320068 , A61B17/3401 , A61B17/3415 , A61B17/3476 , A61B2010/0208 , A61B2017/00115 , A61B2017/00123 , A61B2090/064 , A61M5/3287 , A61M25/0084 , A61M25/06 , A61M2025/09116
摘要： A device for penetrating tissue with reduced force and placing a guidewire is provided. The device includes a driving actuator generating reciprocating motion. A penetrating member having a lumen dimensioned to accommodate a guidewire is provided. A coupler mechanically connects the driving actuator and the penetrating member to transfer the reciprocating motion to the penetrating member. The penetrating member may be coaxial or axially offset from the driving actuator. At least one frictional member facilitates the movement of the guidewire through the lumen for placement at the target tissue. The frictional member(s) may be operated manually or by a guidewire actuator. A housing may also be provided including a channel also dimensioned to accommodate the guidewire, and may further include the frictional member(s) for facilitating movement of the guidewire. The channel and lumen are aligned to permit placement of the guidewire at the target site.
摘要翻译：提供了一种用于以较小力量穿透组织并放置导丝的装置。该装置包括产生往复运动的驱动致动器。提供了具有内腔尺寸以容纳导丝的穿透构件。耦合器将驱动致动器和穿透构件机械连接以将往复运动传递到穿透构件。穿透构件可以与驱动致动器同轴或轴向偏移。至少一个摩擦构件有助于导丝通过内腔的移动以放置在靶组织处。摩擦构件可以手动地或通过导丝线致动器操作。还可以设置壳体，其包括尺寸适于容纳导丝的通道，并且还可以包括用于促进导丝的移动的摩擦构件。通道和内腔对齐以允许导丝放置在目标位置。

7. 发明申请

US20160303360A1 Ultrasonic Transducer and Transdermal Delivery System 审中-公开
标题翻译：超声波传感器和透皮递送系统
公开(公告)号：US20160303360A1
公开(公告)日：2016-10-20
申请号：US15130665
申请日：2016-04-15
申请人： Actuated Medical, Inc.
发明人： Maureen L. Mulvihill , Kevin A. Snook , Rob Van Ess, II , Ryan S. Clement , Jason A. Showers , Andrew J. Meehan , Roger B. Bagwell
IPC分类号： A61M37/00 , H02N2/00 , B06B1/06 , A61N1/30
CPC分类号： A61M37/0092 , A61M2037/0007 , A61N1/0428 , A61N1/303 , B06B1/0603
摘要： A transdermal delivery system including a first passive portion containing a substance for delivery in a reservoir and a second active portion that includes an ultrasonic source. The ultrasonic source includes piezoelectric element(s) that receive electrical stimulation and move radially. A support member fixed to one side of the piezoelectric element(s) restricts movement at that side, so the opposite side expands and contracts. A fulcrum attached to the support member opposite of the piezoelectric element(s) provides an anchor point about which the piezoelectric element(s) bends and flexes upon electrical stimulation. This provides a low ultrasound frequency with a smaller sized transducer than previously known. The active portion is applied to provide electrical stimulation for a certain length of time and removed, whereas the passive portion may remain for a longer duration. A feedback loop also monitors and adjusts the electrical stimulation to maintain a uniform or constant resonance frequency.
摘要翻译：一种透皮递送系统，包括含有用于在储存器中输送的物质的第一被动部分和包括超声波源的第二活性部分。超声波源包括接受电刺激并径向移动的压电元件。固定在压电元件的一侧的支撑构件限制该侧的运动，因此相对侧膨胀和收缩。连接到与压电元件相对的支撑构件的支点提供了锚定点，压电元件在电刺激时弯曲并弯曲。这提供了具有比先前已知的更小尺寸的换能器的低超声频率。施加有源部分以在一定长度的时间内提供电刺激并去除，而被动部分可以保持更长的持续时间。反馈回路还监测和调整电刺激以保持均匀或恒定的共振频率。

8. 发明申请

US20150208925A1 Photoacoustic Needle Insertion Platform 审中-公开
标题翻译：光声针插入平台
公开(公告)号：US20150208925A1
公开(公告)日：2015-07-30
申请号：US14601784
申请日：2015-01-21
申请人： Actuated Medical, Inc.
发明人： Roger B Bagwell , Kevin A. Snook , Ryan S. Clement , Andrew J. Meehan
IPC分类号： A61B5/00 , A61B10/02
CPC分类号： A61B5/0095 , A61B5/4869 , A61B5/4887 , A61B5/6848 , A61B10/0233 , A61B10/0275
摘要： A device for differentiating tissue is provided that has a first laser transmission source that outputs a first laser beam in which output from the first laser transmission source is transferred into tissue. A second laser transmission source is provided that outputs a second laser beam that has a wavelength that is different than the first laser beam. Output from the first and second laser transmission sources is transferred into the tissue. A needle system is present for insertion into the tissue along with an acoustic receiver that receives acoustic waves that are created upon the transfer of the output of the first and second laser transmission sources into the tissue. An associated method is also provided.
摘要翻译：提供了一种用于区分组织的装置，其具有第一激光传输源，其输出第一激光束，其中来自第一激光传输源的输出被转移到组织中。提供第二激光传输源，其输出具有与第一激光束不同的波长的第二激光束。来自第一和第二激光传输源的输出被传送到组织中。存在用于插入到组织中的针系统，以及接收在将第一和第二激光传输源的输出传递到组织中时产生的声波的声学接收器。还提供了相关联的方法。

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