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    • 1. 发明授权
      US5586180A Method of automatic speech direction reversal and circuit configuration for implementing the method 失效
    • Method of automatic speech direction reversal and circuit configuration for implementing the method
    • 自动语音方向反转和电路配置方法实现方法
    • US5586180A
    • 1996-12-17
    • US300430
    • 1994-09-02
    • Achim Degenhardt , Thomas Henkel
    • Achim Degenhardt , Thomas Henkel
    • H04B1/46 , G10L11/02 , H04M1/60 , H04M9/08
    • G10L25/78 , H04M9/08
    • In a method and a circuit for automatic speech direction reversal a reception signal with variable damping is furnished to a loudspeaker and a signal with a variable damping from a microphone is provided as the transmission signal. The reception signal and microphone signal are continuously classified as speech signal or noise. The one signal which is classified as a speech signal, is damped at a first damping value and the other signal is damped at a second damping value, which is greater than the first. These settings are maintained until a signal is classified as noise. When both signals are classified as speech signals, the preceding damping values are retained. When both signals are classified as noise, both attenuations are set at a third damping value located between the first and second damping values. A transition from the first or second damping value to the third damping value is performed more slowly than a transition from the third damping value to the first or second damping value or a transition from the first to the second damping value, and vice versa.
    • 在自动语音方向反转的方法和电路中，向扬声器提供具有可变阻尼的接收信号，并且提供具有来自麦克风的可变阻尼的信号作为发送信号。 接收信号和麦克风信号被连续分类为语音信号或噪声。 分类为语音信号的一个信号以第一阻尼值衰减，另一个信号以大于第一阻尼值的第二阻尼值衰减。 保持这些设置，直到信号被分类为噪声。 当两个信号被分类为语音信号时，保留前面的阻尼值。 当两个信号被分类为噪声时，两个衰减都被设置在位于第一和第二阻尼值之间的第三阻尼值。 从第一阻尼值或第二阻尼值到第三阻尼值的转变比从第三阻尼值到第一或第二阻尼值的转变或从第一阻尼值到第二阻尼值的转变更慢地进行，反之亦然。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 4. 发明授权
      US5679525A Epstein-barr virus transcription factor binding assay 失效
    • Epstein-barr virus transcription factor binding assay
    • 爱泼斯坦 - 巴尔病毒转录因子结合测定
    • US5679525A
    • 1997-10-21
    • US704398
    • 1996-07-17
    • Michael Gregory Peterson , Thomas Henkel
    • Michael Gregory Peterson , Thomas Henkel
    • C07K14/05 , C07K14/47 , C12N15/12 , C12Q1/68 , G01N33/50
    • G01N33/5091 , C07K14/005 , C07K14/4705 , C12Q1/6897 , G01N33/5008 , G01N33/5011 , G01N33/5023 , C12N2710/16222
    • The invention provides methods and compositions for identifying pharmacological agents useful in the diagnosis or treatment of disease associated with the expression of a gene modulated by a transcription complex containing at least CBF1 and a transcription factor. The methods involve combining CBF1, the Epstein-Barr virus transcription factor EBNA2 or cellular homolog thereof, and a candidate pharmacological agent. This mixture is incubated under conditions whereby, but for the presence of the candidate pharmacological agent, CBF1 binds EBNA2. The absence of selective binding indicates that the candidate pharmacological agent is capable of selectively modulating the expression of a gene dependent on CBF1-transcription factor binding. The mixture may further comprise a CBF1 binding element including the nucleotide sequence: C-G-T-G-G-G-A-A. This mixture is incubated under conditions whereby, but for the presence of the candidate pharmacological agent, a transcription complex comprising both polypeptides bound, directly or indirectly to the nucleic acid is formed. The methods are particularly suited to high-throughput screening where one or more steps are performed by a computer controlled electromechanical robot comprising an axial rotatable arm and said solid substrate is a portion of a well of a microtiter plate.
    • 本发明提供用于鉴定可用于诊断或治疗由至少含有CBF1和转录因子的转录复合物调节的基因的表达相关疾病的药理学试剂的方法和组合物。 所述方法包括将CBF1，爱泼斯坦 - 巴尔病毒转录因子EBNA2或其细胞同源物和候选药理学试剂结合。 该混合物在条件下孵育，但是对于候选药理学试剂的存在，CBF1结合EBNA2。 不存在选择性结合表明候选药理学试剂能够选择性调节依赖于CBF1转录因子结合的基因的表达。 该混合物可以进一步包含包含核苷酸序列：C-G-T-G-G-G-A-A的CBF1结合元件。 该混合物在条件下孵育，但是对于候选药理学试剂的存在，形成包含与核酸直接或间接结合的两个多肽的转录复合体。 该方法特别适用于高通量筛选，其中一个或多个步骤由包括轴向可旋转臂的计算机控制的机电机器人执行，所述固体基质是微量滴定板的孔的一部分。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 7. 发明申请
      US20050069030A1 Channel with domain crossing 有权
    • Channel with domain crossing
    • 频道与域交叉
    • US20050069030A1
    • 2005-03-31
    • US10917966
    • 2004-08-13
    • Thomas Henkel
    • Thomas Henkel
    • G01R31/28 , G01R31/317 , H04B3/46
    • G01R31/31727
    • A channel adapted for at least one of providing and receiving signals includes a channel clock domain, whereby said channel clock domain is under clock control of a channel clock. The channel clock domain includes at least one of: a drive path adapted for providing signals and a receive path adapted for receiving signals. The channel also includes a service clock domain adapted for at least one of providing data to and receiving data from said channel clock domain, whereby said service clock domain is under clock control of a service clock.
    • 适于提供和接收信号中的至少一个信道的信道包括信道时钟域，由此所述信道时钟域在信道时钟的时钟控制之下。 信道时钟域包括以下中的至少一个：适于提供信号的驱动路径和适于接收信号的接收路径。 信道还包括业务时钟域，适用于向所述信道时钟域提供数据和从所述信道时钟域接收数据中的至少一个，由此所述业务时钟域在服务时钟的时钟控制之下。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 9. 发明授权
      US6055644A Multi-channel architecture with channel independent clock signals 失效
    • Multi-channel architecture with channel independent clock signals
    • 具有通道独立时钟信号的多通道架构
    • US6055644A
    • 2000-04-25
    • US50289
    • 1998-03-30
    • Thomas Henkel
    • Thomas Henkel
    • G01R31/3183 , G01R31/319 , G06F1/06 , G06F1/04
    • G06F1/06 , G01R31/31922
    • Described is a multi-channel architecture comprising a central master clock generator for generating a central master clock signal and a plurality of channels connectable with inputs or outputs of a device. The multi-channel architecture further includes a channel master clock gate assigned to a respective channel of the plurality of channels, for receiving the central master clock signal and for generating a channel clock signal from the central master clock signal. The multi-channel architecture can be used in a tester arrangement, and preferably in an IC tester. The described multi-channel architecture allows clock signals to be provided for each one of the channels independent of other channels, e.g. to apply a continuous clock signal in one channel while the clock signal in other channels might be changed, e.g. in order to receive new timing edges as references for testing a DUT.
    • 描述了一种多通道架构，其包括用于产生中央主时钟信号的中央主时钟发生器和可与设备的输入或输出连接的多个通道。 多通道架构还包括分配给多个通道中的相应通道的通道主时钟门，用于接收中央主时钟信号并用于从中央主时钟信号产生通道时钟信号。 多通道架构可以用于测试器布置，并且优选地在IC测试器中使用。 所描述的多通道架构允许为独立于其他通道的每个通道提供时钟信号，例如。 以在一个通道中施加连续的时钟信号，而其它通道中的时钟信号可能被改变，例如， 以便接收新的时序边缘作为测试DUT的参考。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
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