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1. 发明授权

US08527058B2 Methods and systems of automatically detecting an impedance of one or more electrodes in a cochlear implant system 有权
标题翻译：在耳蜗植入系统中自动检测一个或多个电极的阻抗的方法和系统
公开(公告)号：US08527058B2
公开(公告)日：2013-09-03
申请号：US13571679
申请日：2012-08-10
申请人： Abhijit Kulkarni , Lakshmi N. Mishra , Leonid M. Litvak , Mark B. Downing , Aniket Saoji , Patrick T. Wong
发明人： Abhijit Kulkarni , Lakshmi N. Mishra , Leonid M. Litvak , Mark B. Downing , Aniket Saoji , Patrick T. Wong
IPC分类号： A61N1/36 , A61N1/18
CPC分类号： A61N1/36036 , A61N2001/083
摘要： An exemplary method includes a sound processing unit 1) directing an implantable cochlear stimulator coupled to a plurality of electrodes to generate an electrical stimulation current in accordance with one or more stimulation parameters, 2) automatically detecting an impedance of at least one of the electrodes, and 3) directing, in accordance with the detected impedance, the implantable cochlear stimulator to adjust a pulse width of the electrical stimulation current to maintain constant a total electric charge level of the electrical stimulation current.
摘要翻译：一种示例性方法包括声音处理单元1）引导耦合到多个电极的可植入耳蜗刺激器以根据一个或多个刺激参数产生电刺激电流，2）自动检测至少一个电极的阻抗，以及3）根据检测到的阻抗指示可植入的耳蜗刺激器，以调整电刺激电流的脉冲宽度以保持电刺激电流的总电荷水平的恒定。

2. 发明申请

US20120303096A1 METHODS AND SYSTEMS OF AUTOMATICALLY DETECTING AN IMPEDANCE OF ONE OR MORE ELECTRODES IN A COCHLEAR IMPLANT SYSTEM 有权
标题翻译：自动检测一个或多个电极在COCHLEAR植入系统中的阻抗的方法和系统
公开(公告)号：US20120303096A1
公开(公告)日：2012-11-29
申请号：US13571679
申请日：2012-08-10
申请人： Abhijit Kulkarni , Lakshmi N. Mishra , Leonid M. Litvak , Mark B. Downing , Aniket Saoji , Patrick T. Wong
发明人： Abhijit Kulkarni , Lakshmi N. Mishra , Leonid M. Litvak , Mark B. Downing , Aniket Saoji , Patrick T. Wong
IPC分类号： A61F11/04 , H04R25/00
CPC分类号： A61N1/36036 , A61N2001/083
摘要： An exemplary method includes a sound processing unit 1) directing an implantable cochlear stimulator coupled to a plurality of electrodes to generate an electrical stimulation current in accordance with one or more stimulation parameters, 2) automatically detecting an impedance of at least one of the electrodes, and 3) directing, in accordance with the detected impedance, the implantable cochlear stimulator to adjust a pulse width of the electrical stimulation current to maintain constant a total electric charge level of the electrical stimulation current.
摘要翻译：一种示例性方法包括声音处理单元1）引导耦合到多个电极的可植入耳蜗刺激器以根据一个或多个刺激参数产生电刺激电流，2）自动检测至少一个电极的阻抗，以及3）根据检测到的阻抗指示可植入的耳蜗刺激器，以调整电刺激电流的脉冲宽度以保持电刺激电流的总电荷水平的恒定。

3. 发明授权

US08265766B1 Methods and systems of automatically detecting an impedance of one or more electrodes in a cochlear implant system 有权
标题翻译：在耳蜗植入系统中自动检测一个或多个电极的阻抗的方法和系统
公开(公告)号：US08265766B1
公开(公告)日：2012-09-11
申请号：US12342859
申请日：2008-12-23
申请人： Abhijit Kulkarni , Lakshmi N. Mishra , Leonid M. Litvak , Mark B. Downing , Aniket Saoji , Patrick T. Wong
发明人： Abhijit Kulkarni , Lakshmi N. Mishra , Leonid M. Litvak , Mark B. Downing , Aniket Saoji , Patrick T. Wong
IPC分类号： A61N1/36 , A61N1/18
CPC分类号： A61N1/36036 , A61N2001/083
摘要： Methods and systems for automatically detecting an impedance of one or more electrodes in a cochlear implant system include providing an implantable cochlear stimulator coupled to one or more electrodes, generating an electrical stimulation current with the implantable cochlear stimulator in accordance with stimulation parameters, automatically detecting an impedance of at least one of the electrodes in accordance with a predefined schedule, and performing a predefined action in accordance with the detected impedance.
摘要翻译：用于自动检测耳蜗植入系统中的一个或多个电极的阻抗的方法和系统包括提供耦合到一个或多个电极的可植入耳蜗刺激器，根据刺激参数与可植入耳蜗刺激器产生电刺激电流，自动检测至少一个电极的阻抗，并根据检测到的阻抗执行预定义的动作。

4. 发明授权

US09320898B2 Systems and methods for facilitating apical electrode stimulation by an electro-acoustic stimulation system 有权
标题翻译：通过电声刺激系统促进顶端电极刺激的系统和方法
公开(公告)号：US09320898B2
公开(公告)日：2016-04-26
申请号：US14375123
申请日：2012-01-31
申请人： Mark B. Downing , Leonid M. Litvak
发明人： Mark B. Downing , Leonid M. Litvak
IPC分类号： A61N1/36 , A61N1/05 , A61N1/372 , H04R25/02
CPC分类号： A61N1/36032 , A61N1/0541 , A61N1/36036 , A61N1/37247 , H04R25/02 , H04R25/606 , H04R2225/67
摘要： An exemplary electro-acoustic stimulation (EAS) device includes 1) a detection facility configured to detect audio content presented to a patient and included in an acoustic stimulation frequency range, 2) an acoustic stimulation management facility configured to direct a loud-speaker to apply acoustic stimulation representative of the audio content included in the acoustic stimulation frequency range to the patient, and 3) an electrical stimulation management facility configured to direct a cochlear implant implanted within the patient to apply sub-threshold electrical stimulation to the patient by way of one or more electrodes disposed within an apical region of a cochlea of the patient together with the application of the acoustic stimulation. Corresponding systems and methods are also disclosed.
摘要翻译：示例性电声刺激（EAS）装置包括：1）检测设备，被配置为检测呈现给患者并包括在声刺激频率范围内的音频内容; 2）声音刺激管理设备，被配置为引导扬声器应用声学刺激代表包括在患者的声学刺激频率范围内的音频内容，以及3）电刺激管理设备，其被配置为引导植入在患者体内的人工耳蜗植入物以通过一个方式向患者施加亚阈值电刺激或多个设置在患者的耳蜗的顶端区域内的电极以及声刺激的应用。还公开了相应的系统和方法。

5. 发明申请

US20150012053A1 SYSTEMS AND METHODS FOR FACILITATING APICAL ELECTRODE STIMULATION BY AN ELECTRO-ACOUSTIC STIMULATION SYSTEM 有权
标题翻译：通过电声刺激系统促进生物电刺激的系统和方法
公开(公告)号：US20150012053A1
公开(公告)日：2015-01-08
申请号：US14375123
申请日：2012-01-31
申请人： Mark B. Downing , Leonid M. Litvak
发明人： Mark B. Downing , Leonid M. Litvak
IPC分类号： A61N1/36 , H04R25/02 , A61N1/372
CPC分类号： A61N1/36032 , A61N1/0541 , A61N1/36036 , A61N1/37247 , H04R25/02 , H04R25/606 , H04R2225/67
摘要： An exemplary electro-acoustic stimulation (EAS) device includes 1) a detection facility configured to detect audio content presented to a patient and included in an acoustic stimulation frequency range, 2) an acoustic stimulation management facility configured to direct a loud-speaker to apply acoustic stimulation representative of the audio content included in the acoustic stimulation frequency range to the patient, and 3) an electrical stimulation management facility configured to direct a cochlear implant implanted within the patient to apply sub-threshold electrical stimulation to the patient by way of one or more electrodes disposed within an apical region of a cochlea of the patient together with the application of the acoustic stimulation. Corresponding systems and methods are also disclosed.
摘要翻译：示例性电声刺激（EAS）装置包括：1）检测设备，被配置为检测呈现给患者并包括在声刺激频率范围内的音频内容; 2）声音刺激管理设备，被配置为引导扬声器应用声学刺激代表包括在患者的声学刺激频率范围内的音频内容，以及3）电刺激管理设备，其被配置为引导植入在患者体内的人工耳蜗植入物以通过一个方式向患者施加亚阈值电刺激或多个设置在患者的耳蜗的顶端区域内的电极以及声刺激的应用。还公开了相应的系统和方法。

6. 发明授权

US09474546B1 Pre-curved electrode array insertion tools 有权
标题翻译：预弯曲电极阵列插入工具
公开(公告)号：US09474546B1
公开(公告)日：2016-10-25
申请号：US12425868
申请日：2009-04-17
申请人： William G. Orinski , Steve J. Blomquist , Mark B. Downing
发明人： William G. Orinski , Steve J. Blomquist , Mark B. Downing
IPC分类号： A61N1/05 , A61B17/34 , A61B17/00 , A61N1/36
CPC分类号： A61B17/3468 , A61B2017/00477 , A61B2017/00787 , A61N1/0541 , A61N1/36036
摘要： Exemplary insertion tools for facilitating insertion of an electrode array into a bodily orifice include a stylet assembly having a stylet configured to be inserted into a lumen of the electrode array, a slide assembly configured to at least partially house the stylet assembly, and a handle assembly configured to engage at least a portion of the slide assembly. The slide assembly may be configured to selectively disengage from the handle assembly. The stylet assembly may be configured to selectively disengage from the slide assembly while the stylet is still inserted into the lumen of the electrode array. Corresponding systems and methods are also described.
摘要翻译：用于便于将电极阵列插入身体孔口的示例性插入工具包括具有被设置成插入到电极阵列的内腔中的探针的探针组件，构造成至少部分地容纳探针组件的滑动组件和手柄组件被配置为接合所述滑动组件的至少一部分。滑动组件可以构造成选择性地与手柄组件脱离接合。探针组件可被配置为当探针仍插入到电极阵列的内腔中时选择性地从滑动组件脱离。还描述了相应的系统和方法。

7. 发明申请

US20140358174A1 Intraneural Implant 审中-公开
标题翻译：神经内植入
公开(公告)号：US20140358174A1
公开(公告)日：2014-12-04
申请号：US14372380
申请日：2012-01-25
申请人： Chuladatta Thenuwara , Mark B. Downing
发明人： Chuladatta Thenuwara , Mark B. Downing
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61B2017/320044 , A61N1/0551 , A61N1/0558 , A61N1/3605
摘要： An intraneural implant comprises a lead comprising a number of electrode wires, a number of electrodes communicatively coupled to the electrode wires, the electrodes forming an electrode array, and an overmold surrounding the electrode wires and at least a portion of the electrodes, and a blunt dissector tip coupled to the lead to penetrate nerve tissues as the electrode array is implanted. An intraneural implant system comprises a flexible lead. The flexible lead comprises a lead body, an electrode array communicatively coupled to the lead body, a blunt dissector tip to penetrate a nerve bundle as the electrode array is implanted into the nerve bundle, and an implantation tool coupled to the electrode array to implant the electrode array into the nerve bundle.
摘要翻译：神经内植入物包括引线，其包括多个电极引线，多个电极通信地耦合到电极线，形成电极阵列的电极以及围绕电极线和至少一部分电极的包覆模制，以及钝器剥离器尖端耦合到引线，以便在植入电极阵列时穿透神经组织。内膜植入系统包括柔性引线。柔性引线包括引线本体，与引线主体通信地连接的电极阵列，当电极阵列被植入神经束时穿过神经束的钝性解剖器尖端以及与该电极阵列相连接的植入工具电极阵列进入神经束。

8. 发明授权

US09561361B2 Atraumatic electrode lead 有权
标题翻译：无创电极引线
公开(公告)号：US09561361B2
公开(公告)日：2017-02-07
申请号：US14345596
申请日：2011-10-07
申请人： Chuladatta Thenuwara , Rosa Gallego , Lidia Vasquez , Mark B. Downing
发明人： Chuladatta Thenuwara , Rosa Gallego , Lidia Vasquez , Mark B. Downing
IPC分类号： A61N1/05 , A61N1/36 , H04R25/00 , H04R31/00
CPC分类号： A61N1/0541 , A61N1/36036 , H04R25/00 , H04R31/006 , H04R2225/67 , H04R2231/003 , Y10T29/49213 , Y10T29/4922
摘要： A cochlear implant includes a processor, an array of electrodes disposed along a flexible body and a lead body connecting the processor to the array of electrodes. The lead body includes a first tube having a first outside diameter, a second tube having a second outside diameter smaller than the first diameter, a portion of the second tube being disposed within the first tube, and wires passing through the first tube and the second tube, the wires comprising a helically coiled portion. A method for forming a lead body is also provided.
摘要翻译：耳蜗植入物包括处理器，沿着柔性体设置的电极阵列和将处理器连接到电极阵列的引线体。引线体包括具有第一外径的第一管，具有小于第一直径的第二外径的第二管，第二管的一部分设置在第一管内，以及穿过第一管和第二管的第二管管，包括螺旋卷曲部分的线。还提供了一种用于形成引线体的方法。

9. 发明授权

US09415207B2 Mid-scalar electrode array 有权
标题翻译：中标电极阵列
公开(公告)号：US09415207B2
公开(公告)日：2016-08-16
申请号：US14116089
申请日：2011-05-11
申请人： Chuladatta Thenuwara , Rosa Gallegos , Lidia Vasquez , Mark B. Downing
发明人： Chuladatta Thenuwara , Rosa Gallegos , Lidia Vasquez , Mark B. Downing
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/0541 , A61N1/36036 , Y10T29/49224
摘要： In one example, a cochlear lead includes a flexible body, an array of electrodes in the flexible body, and a plurality of wires passing along the array of electrodes. The plurality of wires includes a flexural geometry between each pair of adjacent electrodes and a substantially straight geometry over the electrodes. A method for forming an electrode array with a reduced apical cross section is also provided.
摘要翻译：在一个示例中，耳蜗引线包括柔性体，柔性体中的电极阵列，以及沿着电极阵列通过的多根线。多根电线包括每对相邻电极之间的弯曲几何形状以及在电极上的基本上直的几何形状。还提供了一种形成具有减小的顶端横截面的电极阵列的方法。

10. 发明授权

US09352149B2 Retention of a magnet in a cochlear implant 有权
标题翻译：在耳蜗植入物中保留磁体
公开(公告)号：US09352149B2
公开(公告)日：2016-05-31
申请号：US14344200
申请日：2011-09-22
申请人： Chuladatta Thenuwara , Mark B. Downing
发明人： Chuladatta Thenuwara , Mark B. Downing
IPC分类号： A61N1/00 , A61N1/08 , A61N1/375 , A61N1/36 , A61N1/372 , B29C45/14 , B29K83/00 , B29L31/00
CPC分类号： A61N1/08 , A61N1/36036 , A61N1/37229 , A61N1/375 , B29C45/14819 , B29K2083/005 , B29K2995/0008 , B29L2031/753
摘要： A system for retaining a magnet in a cochlear implant, comprising a retainer embedded within an encapsulant of the cochlear implant, and a magnet case engaged with the retainer. A retainer for retaining a magnet within a cochlear implant comprising a number of first fasteners that couple with a number of corresponding second fasteners of a magnet case hermetically sealing the magnet, and a number of supports embedded within an encapsulant of the cochlear implant.
摘要翻译：一种用于将磁体保持在耳蜗植入物中的系统，包括嵌入在所述耳蜗植入物的密封剂内的保持器和与所述保持器接合的磁体盒。用于将磁体保持在耳蜗植入物内的保持器，其包括多个第一紧固件，所述第一紧固件与密封所述磁体的磁体壳体的多个对应的第二紧固件耦合，以及嵌入在所述耳蜗植入物的密封剂内的多个支撑件。

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