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1. 发明授权

US09788739B2 Management of cardiac data transmissions 有权
公开(公告)号：US09788739B2
公开(公告)日：2017-10-17
申请号：US13872449
申请日：2013-04-29
申请人： ANGEL MEDICAL SYSTEMS, INC.
发明人： Michael Sasha John , David R. Fischell
IPC分类号： A61B5/0402 , A61B5/04 , A61B5/00 , A61B5/02 , G06F19/00 , A61N1/08
CPC分类号： A61B5/04 , A61B5/0031 , A61B5/02028 , A61B5/7264 , A61B2560/0295 , A61N1/08 , G06F19/00 , G06F19/3418 , Y10S128/903
摘要： A medical alarm communications system comprises a pager like device to be kept near a patient. The pager like device communicates medical alerts regarding the patient to a remote central station, which can provide therapeutic and/or diagnostic assistance by communicating to the pager like device. When the pager like device determines that an alert should be sent to the central station, it attempts to establish communication with the central station according to a primary communication protocol. If this attempt is unsuccessful according to some predetermined criteria (e.g. too much time has elapsed before communication is established), then the pager like device generates a message to the patient indicative of the failure, and The attempts to establish communication with the central station according to a secondary communication protocol.

2. 发明授权

US09468383B2 System for detecting cardiac ischemia and irregular heart rhythms 有权
标题翻译：检测心脏缺血和不规则心律的系统
公开(公告)号：US09468383B2
公开(公告)日：2016-10-18
申请号：US14749873
申请日：2015-06-25
申请人： ANGEL MEDICAL SYSTEMS, INC.
发明人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell
IPC分类号： A61B5/0452 , A61B5/0245 , A61B5/0468 , A61B5/00 , A61B5/04 , A61B5/042 , A61B5/0456 , A61B5/0472
CPC分类号： A61B5/02455 , A61B5/0031 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/746 , A61B5/7465 , A61B2560/0209
摘要： A system for detecting acute ischemia includes at least two sensors configured for obtaining electrical signals from a patient's heart, analog-to-digital converter circuitry for digitizing the signal to produce data segments, and a processor configured to analyze data segments to determine if they represent an abnormal heart rhythm. Certain types of abnormal rhythm segments are also checked for acute ischemia. If enough of the abnormal heart rhythm segments manifest acute ischemia, a first type of alarm event is generated. If persistent abnormal heart rhythm segments do not manifest acute ischemia, a second type of alarm event is generated.
摘要翻译：用于检测急性缺血的系统包括至少两个被配置用于从患者心脏获得电信号的传感器，用于数字化信号以产生数据段的模数转换器电路，以及配置成分析数据段以确定它们是否表示心律异常还检查某些类型的异常节律段是否为急性缺血。如果足够的异常心律节段显示急性缺血，则产生第一种类型的报警事件。如果持续不正常的心律节段不表现为急性缺血，则产生第二种类型的报警事件。

3. 发明授权

US09415228B1 System for ischemia detection based on adjustable paced beat analysis timing 有权
标题翻译：基于可调节节拍分析时序的缺血检测系统
公开(公告)号：US09415228B1
公开(公告)日：2016-08-16
申请号：US14853107
申请日：2015-09-14
申请人： ANGEL MEDICAL SYSTEMS, INC.
发明人： David R. Fischell , Michael Sasha John , Bruce Hopenfeld
IPC分类号： A61N1/37 , A61N1/02
CPC分类号： A61N1/3702 , A61B5/0452 , A61B5/0472 , A61B5/4836 , A61B5/7282 , A61N1/025 , A61N1/362 , A61N1/368 , A61N1/3684
摘要： A device for detecting cardiac ischemia is disclosed. The device includes a processor that is configured to distinguish between ventricularly paced beats and supraventricular beats. The processor applies different ischemia tests to the two different beat types, and generates alert when it detects ischemia. The processor collects and counts the ST segment deviation values for ventricularly paced beats for a pre-set time period. The processor then determines if the number of ventricularly paced beats is insufficient to perform ischemia detection. If so, then the processor collects ST deviation values for additional paced beats. When the processor determines that a sufficient number of ventricularly paced beats have been acquired, it identifies ischemic beats by the application of ischemia detection criteria to the ST deviation values of the collected ventricularly paced beats.
摘要翻译：公开了一种用于检测心脏缺血的装置。该装置包括被配置为区分心室起搏节拍和室上搏动的处理器。处理器对两种不同的节拍类型应用不同的缺血试验，并在检测到缺血时产生警报。处理器在预设时间段内收集并计算心室起搏节拍的ST段偏差值。然后处理器确定心室起搏节拍的数量是否不足以进行缺血检测。如果是这样，那么处理器收集ST偏差值，以获得额外的节奏。当处理器确定已经获得足够数量的心室起搏节拍时，其通过将局部缺血检测标准应用于所收集的心室起搏节拍的ST偏差值来识别缺血搏动。

4. 发明授权

US09174057B1 Cardiac event detection based on selective pacing for establishing a paced heart signal parameter baseline 有权
标题翻译：基于选择性起搏的心脏事件检测建立起搏心跳信号参数基线
公开(公告)号：US09174057B1
公开(公告)日：2015-11-03
申请号：US14531249
申请日：2014-11-03
申请人： ANGEL MEDICAL SYSTEMS, INC.
发明人： David R. Fischell , Michael Sasha John , Bruce Hopenfeld
IPC分类号： A61N1/00 , A61N1/37 , A61N1/362 , A61B5/0452
CPC分类号： A61N1/3702 , A61B5/0452 , A61B5/0472 , A61B5/4836 , A61B5/7282 , A61N1/025 , A61N1/362 , A61N1/368 , A61N1/3684
摘要： A device for detecting cardiac ischemia is disclosed. The device includes a processor that is configured to distinguish between two different heart beats types such as ventricularly paced beats and supraventricular beats. The processor collects separate reference data for a first one of the beat types indicative of the normal values of a cardiac feature. The processor performs an ischemia test to beats of the first type by first checking whether valid reference data exists for that beat type. If so, the ischemia test is based on this reference data. If no valid reference data exists for the firs beat type, the processor applies an ischemia test that is not based on reference data for the first beat type.
摘要翻译：公开了一种用于检测心脏缺血的装置。该装置包括处理器，其被配置为区分两种不同的心跳类型，例如心室起搏节拍和室上搏动。处理器针对指示心脏特征的正常值的节拍类型中的第一个收集单独的参考数据。处理器通过首先检查是否存在针对该节拍类型的有效参考数据来执行第一类型的缺血测试。如果是这样，缺血试验基于该参考数据。如果没有针对第一拍子类型的有效参考数据，则处理器应用不基于第一拍子类型的参考数据的缺血测试。

5. 发明授权

US08457725B1 Alarm testing and backup for implanted medical devices with vibration alerts 有权
标题翻译：具有振动警报的植入式医疗设备的报警测试和备份
公开(公告)号：US08457725B1
公开(公告)日：2013-06-04
申请号：US13633275
申请日：2012-10-02
申请人： David R. Fischell , Angel Medical Systems, Inc.
发明人： David R. Fischell , Michael Sasha John , Jonathan Harwood
IPC分类号： A61B5/04
CPC分类号： A61B5/0402 , A61B5/6846 , A61B2560/0271 , A61B2560/0276 , A61B2562/0219 , A61N1/37258 , G16H40/67
摘要： An implanted device which includes a vibrator having a drive motor and a drive circuit. An accelerometer is connected to the vibrator and senses alarm test data related to the displacement of the vibrator. A power source provides electricity to the implanted device and a processor is configured for bi-directional wireless communication. The processor is configured for receiving a command from an external device for performance of an alarm test and the processor analyzes the alarm test data for generating test results.
摘要翻译：一种植入装置，其包括具有驱动电动机和驱动电路的振动器。加速度传感器连接到振动器，并感测与振动器位移相关的报警测试数据。电源为植入装置提供电力，并且处理器被配置用于双向无线通信。处理器被配置为从外部设备接收命令以执行报警测试，并且处理器分析报警测试数据以产生测试结果。

6. 发明授权

US11426089B1 Advanced cardiovascular monitoring system with normal, elevated, and high heartrate thresholds 有权
公开(公告)号：US11426089B1
公开(公告)日：2022-08-30
申请号：US17304679
申请日：2021-06-24
申请人： ANGEL MEDICAL SYSTEMS, INC.
发明人： David R. Fischell , Michael Sasha John , David Keenan , Steve Johnson , Gregg Turi
IPC分类号： A61B5/00 , A61B5/024 , A61B5/352 , A61B5/358 , A61B5/355 , A61B5/29
摘要： A device for detecting acute coronary syndrome (ACS) events, arrythmias, heart rate abnormalities, medication problems such as non-compliance or ineffective amount or type of medication, and demand/supply related cardiac ischemia is disclosed. The device may have both implanted and external components and can communicate with other user devices such as smartphones and smartwatches for monitoring and alerting in response to detected medically relevant events or states of a patient. The processor is configured to provide event detection based upon various criteria including what is found to be statistically abnormal for a patient or what has been defined by a doctor to be abnormal. A patient's cardiovascular condition can be tracked over time using histogram, trend, and summary information related to heart rate and/or cardiac features such as those measured from the S-T segment of heartbeats. Heartbeats that are elevated but which are below what is defined as high, are used to provide medically relevant detections.

7. 发明授权

US09005130B2 Histogram based generation of cardiac state detection thresholds 有权
标题翻译：基于直方图的心脏状态检测阈值生成
公开(公告)号：US09005130B2
公开(公告)日：2015-04-14
申请号：US14101499
申请日：2013-12-10
申请人： Angel Medical Systems, Inc.
发明人： David R. Fischell , Robert E. Fischell , Jonathan Harwood , Steven R. Johnson
IPC分类号： A61B5/0452 , A61B5/0472 , A61B5/00 , A61N1/02 , A61N1/372 , A61B5/024 , A61B5/0245 , A61B5/04 , A61B5/042 , A61B5/0432 , A61B5/044
CPC分类号： A61B5/0472 , A61B5/0006 , A61B5/0031 , A61B5/02405 , A61B5/02455 , A61B5/04012 , A61B5/042 , A61B5/0432 , A61B5/044 , A61B5/0452 , A61B5/413 , A61B5/686 , A61B5/746 , A61N1/025 , A61N1/37211 , A61N1/37247
摘要： A method for tracking cardiac conditions is disclosed. An electrical signal from a patient's heart is sensed. A heart signal parameter value and an associated heart rate value are computed from the electrical signal. Based on the heart rate value, one of a plurality of histograms stored in a histogram memory is updated with the heart signal parameter value. After a data collection time period has elapsed, a statistical value of the heart signal parameter is computed from the selected histogram. A detection threshold for abnormal values of the heart signal parameter is then computed based on the statistical value.
摘要翻译：公开了一种跟踪心脏病症的方法。感测到来自患者心脏的电信号。从电信号计算心脏信号参数值和相关心率值。基于心率值，存储在直方图存储器中的多个直方图之一用心脏信号参数值更新。在数据收集时间段过去之后，根据选择的直方图计算心脏信号参数的统计值。然后根据统计值计算心脏信号参数异常值的检测阈值。

8. 发明授权

US11357439B1 Advanced cardiovascular monitoring system with personalized st-segment thresholds 有权
公开(公告)号：US11357439B1
公开(公告)日：2022-06-14
申请号：US17304675
申请日：2021-06-24
申请人： ANGEL MEDICAL SYSTEMS, INC.
发明人： David R. Fischell , Michael Sasha John , David Keenan , Steve Johnson , Gregg Turi
IPC分类号： A61B5/00 , A61B5/358 , A61B5/366 , A61B5/36 , A61B5/283 , A61B5/352
摘要： A device for detecting acute coronary syndrome (ACS) events, arrythmias, heart rate abnormalities, medication problems such as non-compliance or ineffective amount or type of medication, and demand/supply related cardiac ischemia is disclosed. The device may have both implanted and external components and can communicate with other user devices such as smartphones and smartwatches for monitoring and alerting in response to detected medically relevant events or states of a patient. The processor is configured to provide event detection based upon various criteria including what is found to be statistically abnormal for a patient or what has been defined by a doctor to be abnormal. A patient's cardiovascular condition can be tracked over time using histogram, trend, and summary information related to heart rate and/or cardiac features such as those measured from the S-T segment of heartbeats. Heartbeats that are elevated but which are below what is defined as high, are used to provide medically relevant detections.

9. 发明授权

US08965494B2 Means and method for the detection of cardiac events 有权
公开(公告)号：US08965494B2
公开(公告)日：2015-02-24
申请号：US14054982
申请日：2013-10-16
申请人： Angel Medical Systems, Inc.
发明人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson
IPC分类号： A61B5/00 , A61B5/0472 , A61B5/0452 , A61N1/37 , A61N1/372 , A61B5/0245 , A61B5/04 , A61B5/042 , A61B5/0432 , A61N1/375
CPC分类号： A61B5/0464 , A61B5/0006 , A61B5/0031 , A61B5/02455 , A61B5/04012 , A61B5/042 , A61B5/0432 , A61B5/0452 , A61B5/0456 , A61B5/046 , A61B5/0472 , A61B5/686 , A61B5/746 , A61B5/7465 , A61N1/3702 , A61N1/37258 , A61N1/3756 , G16H40/67
摘要： Disclosed is a system for the detection of cardiac events that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using different algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and/or an external alarm system (external alarm means) which are activated after the ST segment of the electrogram exceeds a preset threshold.

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