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    • 1. 发明申请
    • SYSTEMS FOR AND METHODS OF TRANSCRANIAL DIRECT CURRENT ELECTRICAL STIMULATION
    • 交叉直接电流刺激的系统和方法
    • US20130204315A1
    • 2013-08-08
    • US13567716
    • 2012-08-06
    • AMORN WONGSARNPIGOONJoseph W. Boggs, IIStuart F. RubinJonathan L. Sakai
    • AMORN WONGSARNPIGOONJoseph W. Boggs, IIStuart F. RubinJonathan L. Sakai
    • A61N1/36
    • A61N1/36025A61N1/0456A61N1/0484A61N1/36021A61N1/361
    • A system according to the present invention provides a portable, non-invasive device adapted to deliver electrical stimulation to a brain, such as to treat tinnitus. Such system is preferably a head-worn system configured to provide transcranial direct current electrical stimulation (tDCS) to a patient, where a therapy based at least partially thereon may be self-administered by the patient. tDCS is a non-invasive method of brain stimulation to treat tinnitus, or other neurological indications, that may provide significant relief. Methods according to the present invention include preferably brief sessions of anodal tDCS to assist in determining adequate electrode location and stimulus intensity by producing transient decreases in tinnitus intensity. Methods may also or alternatively include a number of sessions of cathodal tDCS at a confirmed electrode location and stimulus intensity to provide sustained tinnitus relief. Methods may also or alternatively include a number of maintenance sessions to prolong the sustained relief.
    • 根据本发明的系统提供了一种便于携带的非侵入性装置,其适于向大脑递送电刺激,例如治疗耳鸣。 这种系统优选地是头戴式系统,其被配置为向患者提供经颅直流电刺激(tDCS),其中至少部分地在其上的治疗可以由患者自行施用。 tDCS是一种非侵入性的脑刺激方法来治疗可能提供显着缓解的耳鸣或其他神经系统症状。 根据本发明的方法优选包括阳极tDCS的简短会话,以通过产生耳鸣强度的瞬时降低来帮助确定足够的电极位置和刺激强度。 方法还可以或者可选地包括在确认的电极位置处的阴极tDCS的多次会话和刺激强度以提供持续的耳鸣缓解。 方法还可以或者可选地包括多个维护会话以延长持续的缓解。
    • 10. 发明授权
    • Systems and methods for the treatment of pain through neural fiber stimulation
    • 通过神经纤维刺激治疗疼痛的系统和方法
    • US08788047B2
    • 2014-07-22
    • US13309107
    • 2011-12-01
    • Maria E. BennettJoseph W. Boggs, IIWarren M. GrillJohn Chae
    • Maria E. BennettJoseph W. Boggs, IIWarren M. GrillJohn Chae
    • A61N1/34A61N1/36
    • A61N1/36071A61N1/0551A61N1/36017A61N1/36021A61N1/36057
    • Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
    • 本发明的实施方案提供了通过激活选择性神经纤维来治疗疼痛的系统和方法。 神经纤维可以包含一个或多个传入神经纤维和/或一个或多个传出神经纤维。 如果传入纤维被单独或与传出纤维组合刺激,则施用治疗有效量的电刺激以以接近自然传入活性的方式激活传入途径。 传入纤维可能与肌肉锭,高尔基体腱器官,肌肉锭子的次要受体,关节受体,触觉受体和其他类型的机械感受器和/或本体感受器的主要受体相关联。 如果传出纤维被单独或与传入纤维组合刺激,则施加治疗有效量的电刺激以激活内部和/或外部肌肉纤维,这导致与其相关联的传入纤维的间接活化。